Best Large Grants for Nonprofit Organizations in Tennessee

The NIH is inviting applications for interventions aimed at enhancing cancer screening and preventive services in underserved populations. This initiative focuses on addressing barriers to healthcare access and promoting timely follow-up on abnormal findings. Collaborations with community partners are encouraged to foster effective outreach. The program particularly seeks to engage patients, clinicians, and healthcare settings in improving health equity and outcomes in cancer prevention.

The NIDCD Early Career Research (ECR) Award (R21) supports new scientists establishing independent research careers in areas related to hearing, balance, smell, taste, voice, speech, or language. This grant encourages innovative projects such as secondary data analysis, small research initiatives, and technology development, aiming to generate preliminary data for future R01 applications. All applications must be submitted by 5:00 PM local time of the applicant organization.

The Puffin Foundation's Annual Artist Grant Program focuses on supporting artists and organizations that are often marginalized. In even years, proposals are accepted in fine arts, music, and photography. With a maximum grant size of $3,500, it aims to empower individuals and groups with limited resources to flourish creatively. This initiative reflects the Foundation's commitment to ensuring diverse artistic expressions thrive in society. Applicants must be U.S. citizens or residents, and only one proposal is permitted per year.

The Ryan Myers Memorial Scholarship Fund, established by the Community Foundation of Washington County, MD, supports graduating seniors from various educational backgrounds in Washington County. This scholarship honors Ryan Myers' legacy, encouraging students pursuing higher education, trade schools, or apprenticeships. Ideal candidates reflect Ryan's positive spirit and aspirations, aiming to make a meaningful impact in their communities while achieving their academic and career goals.

The Grants for Coordination of Tribal Temporary Assistance for Needy Families (TANF) and Child Welfare Services aim to support tribal families at risk of abuse or neglect. This funding encourages innovative projects that enhance case management, supportive services, and prevention strategies. Eligible applicants include federally recognized tribal governments and organizations. ACF prioritizes sustainable systems changes, enabling lasting improvements in the coordination of TANF and child welfare programs to better serve vulnerable tribal families.

The Polly W. Roesch Vocal Music Scholarship, established by the Community Foundation for the Land of Lincoln, supports graduating seniors from Sangamon County pursuing degrees in vocal music and performing arts. This scholarship reflects the foundation's commitment to enhancing educational opportunities in the region. Eligible candidates include high school seniors and college students who are direct descendants of U.S. Service Members residing in specific Illinois counties. This initiative aims to foster talent in the arts and provide financial assistance to deserving students.

The Great Lakes Bay Pride Scholarship, offered by the Saginaw Community Foundation, supports Michigan residents dedicated to promoting respect and acceptance across diverse backgrounds. This scholarship is open to high school seniors and college students pursuing undergraduate or Career and Technical Education (CTE) programs, with awards ranging from $500 to $4,000. Eligible applicants must maintain a minimum GPA of 2.5 and demonstrate commitment through volunteer work in the LGBTQ+ community.

The BUILD Grant Program, managed by the USDOT, focuses on enhancing surface transportation infrastructure with substantial local impact. It supports a variety of project sponsors, including state and local governments, in pursuing complex multi-modal initiatives that are often challenging to fund through traditional grants. Established under the American Recovery and Reinvestment Act of 2009, this program reflects a commitment to sustainable and equitable infrastructure development.

The Holland Scholarship, established in honor of Merle Holland Leis Frenzel, aims to support aspiring music students from Saginaw County. Funded by her friends and former students, this scholarship encourages recipients to pursue their musical dreams while honoring the support of her parents, Norton and Virginia Holland. Eligible applicants must maintain a minimum 3.0 GPA, be seniors at Saginaw County public high schools, and be involved in music programs. Awards typically range from $500 to $4,000.

The Sex Worker Giving Circle Grant, launched by the Third Wave Fund, prioritizes funding for grassroots movements led by individuals directly impacted by gender oppression, especially within the sex work community. With a commitment to gender justice, the grant supports organizations that operate with a participatory approach to grantmaking, enabling them to address systemic inequalities. In recent years, the fund has distributed significant resources to empower and sustain these vital movements across the United States.

The Graduate Education Fund offers the South Australia Defence, Space & Cyber Scholarship for scholars from the USA and South Australia. This scholarship supports PhD and Post-Doctoral research in Defence, Space, and Cyber Security, ensuring candidates have affiliations with educational institutions. Awarded funds, up to US $40,000, can cover tuition, travel, and living expenses. Applications are due in March for USA to Australia and September for Australia to USA, promoting collaboration in research between the two nations.

Healthcare Assistance Grant

The MS Focus Healthcare Assistance Grant assists uninsured individuals with the cost of visiting their MS specialist as well as dental assistance. The grant, which can pay for one visit and one follow-up, is designed to assist those already diagnosed with MS who may need a visit to their treating physician to renew a prescription or handle other important needs. 

Applicants give MS Focus staff authorization to negotiate costs directly with the provider, and the fee is paid directly to the doctor. 

The Pulmonary Hypertension Fund, supported by the Patient Advocate Foundation, offers financial assistance for patients dealing with pulmonary hypertension. This fund covers essential healthcare costs, including medication copays and health insurance premiums. Patients must meet specific eligibility criteria, such as having a confirmed diagnosis and appropriate health insurance. Since 1996, the foundation has empowered millions to navigate healthcare challenges, ensuring they receive the care they need without financial burden.

The AAFP Family Medicine Chapter Alliance Grant Awards support the philanthropic efforts of AAFP Constituent Chapters and Chapter Foundations. Since 2006, these grants have been designed to fund activities that align with specific priority areas including education, outreach, and public health initiatives. Eligible applicants include AAFP Chapters and Foundations, focusing on projects that promote community health and wellness.

The R01 grant program aims to address disparities in liver diseases and liver cancer in the United States. It supports multi-level intervention research targeting populations with significant health disparities. With deadlines spanning from February 2024 to June 2027, this initiative encourages innovative approaches to improve health outcomes in underserved communities, ultimately enhancing public health and reducing inequities in healthcare access and treatment.

The AAFP Foundation offers Family Medicine Chapter Engagement Grants to support the philanthropic initiatives of its constituent chapters. Each chapter or chapter foundation can receive $750 to highlight programs focused on Student/Resident education, Member Outreach, or Public Health. This initiative not only showcases the impactful work being done at the chapter level but also aids in fundraising efforts, fostering stronger community connections and improving health outcomes.

The Care Camps Grant supports children with cancer by funding medically supervised oncology camps that provide joy, hope, and healing through outdoor experiences. With the mission to foster a sense of community and shared healing, Care Camps Foundation aims to serve every child and family affected by pediatric cancer in the US and Canada. By collaborating with donors and volunteers, the foundation ensures that each contribution maximizes benefits for the families in need.

The NIH Research Evaluation and Commercialization Hubs (REACH) program aims to facilitate the translation of biomedical discoveries into marketable products to enhance patient care. By funding five new academic entrepreneurship hubs, NIH will provide essential resources such as funding, mentorship, and expertise in product development. These hubs will address high-priority technologies and foster public-private partnerships, ultimately supporting the goals of federal research initiatives and addressing local health needs in underserved areas.

The TTF Advertising for the Environment Grant, established by the Temper of The Times Foundation in 1997, aims to enhance awareness of wildland conservation through marketing initiatives. This grant is exclusively available to 501(c)(3) nonprofit organizations and funds various advertising campaigns to protect native ecosystems. Priority is given to projects that demonstrate measurable impacts on conservation, rather than those focused solely on education.

This funding opportunity aims to enhance health outcomes by addressing healthcare disparities related to non-communicable and chronic diseases in Latin America and among U.S. Hispanic populations. It encourages innovative, interdisciplinary research teams to develop and implement clinical and community-based interventions. Key partnerships with institutions in Latin America are essential for collaboration. Deadlines for applications range from February 2024 to June 2026, with specific dates for standard, renewal, and AIDS-related grant submissions.

The Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance research on asthma and related allergic diseases. This initiative fosters multi-center, multidisciplinary research to explore disease mechanisms and treatment responses. By promoting clinical trials and observational studies, the AADCRC seeks to advance understanding and improve interventions for conditions such as asthma and food allergies, ultimately benefiting public health.

The Woman's National Farm and Garden Association (WNF&GA) Scholarship supports graduate students pursuing careers in conservation and natural resource management. This annual scholarship aims to continue the legacy of conservationists dedicated to protecting our planet's resources. Eligible candidates must demonstrate a strong commitment to environmental stewardship through their academic and community involvement. However, WNF&GA members and their immediate families are excluded from eligibility. The scholarship is a vital resource for future leaders in conservation.

The NIH Countermeasures Against Chemical Threats (CounterACT) initiative invites applications for basic research on chemical agents affecting the nervous system. This program aims to explore the toxicity mechanisms of chemical warfare agents, industrial chemicals, and pesticides. Researchers are encouraged to generate data that could reveal new therapeutic targets and manifestations of toxic exposures, contributing to public health safety against potential chemical threats.

The Animal and Veterinary Innovation Centers (U18) funding opportunity, led by the FDA, aims to foster collaborations with academic institutions to tackle critical veterinary health challenges. This includes addressing Highly Pathogenic Avian Influenza, promoting genomic advancements in agriculture, and developing veterinary solutions for minor species. Applications are invited to enhance animal health and public safety, with Letters of Intent due prior to the July 2024 deadline.

The CAFE Group 

We resource leaders, invest in their genius, and bring people together to reimagine what philanthropy can do.

Founded by Liz and Don Thompson, The CAFE Group is a national nonprofit transforming how change is resourced. 

With a focus on education equity, social capital, and philanthropic transformation, we pair catalytic funding, community-rooted leadership development, and cross-sector collaboration to strengthen the people and institutions shaping a more just future. Everything we do is grounded in relationship, because we believe the way resources move matters just as much as where they land.

The 1954 Project Luminary Award

The 1954 Project Luminary Award celebrates transformational education nonprofit leaders dedicated to serving Black students and communities through powerful investments in their organizations' ability to create lasting change.

The Luminary Experience

Each Luminary organization gets more than funding. Through The 1954 Project, leaders gain a community, a platform, and space to grow with tailored support over the course of the three year journey.​

• $1 Million, Unrestricted: Catalytic funding to expand what’s working.
• Leadership Coaching + Capacity Support: Guidance from peers and experts who are committed to helping you build a lasting, impactful organization.
• National Network: Luminaries join a powerful community of innovators, change-makers, and visionaries driving systemic progress to support students and communities across the U.S.

The 1954 Project’s Impact Areas

We focus on three interconnected areas critical to advancing equity:

• Innovation in Teaching and Learning: Create education models that center Black students through culturally affirming approaches that challenge traditional structures and transform how learning happens, ultimately serving all students. 
• Diversity in Education: Build pathways that increase and sustain Black educators and education leaders who transform where and how students learn.
• Pathways to Economic Mobility: Build pathways to wealth, ownership, and economic power for Black students, families, and communities through innovative educational programming.

Our Selection Criteria

We seek out extraordinary applicants who embody our values and vision across three categories:

Leader: We look for leaders whose influence and vision contribute to the collective well-being and advancement of the Black community. These leaders:

• Are Visionary: They demonstrate a strategic and pragmatic mindset, articulating a transformative vision for significant, positive change.
• Show Demonstrated Commitment: They embody steadfast dedication to your cause, inspiring and influencing others, and galvanizing community involvement.
• Are Adaptive: They assertively tackle challenges, turning setbacks into opportunities for innovation, while maintaining humility and thoughtfulness in problem-solving.

Organization: We look for organizations that drive significant change, anchored by a deep love for people and driven by the genius within communities of color. These organizations: 

• Have a Defined Problem: They clearly identify the issue they are addressing and explain in detail how your organization tackles root causes. 
• Take a Strategic Approach: They have clear, measurable, and achievable organizational goals with a well-defined strategy informed by thorough analysis. 
• Show Demonstrated Impact: They have a tested model that has produced positive results, incorporating continuous learning and iteration. 
• Have a Transformation Plan: They present a clear plan for using the $1M award to advance your organization's mission, vision, and long-term goals. 
• Embrace Collaboration: They use collaborate to build partnerships based on trust, love, and common goals. 

Radical Imagination: We seek leaders who challenge and redesign societal norms to build a just and equitable future. They demonstrate:

• Community-Rooted Leadership: They maintain and cultivate genuine community ties, integrating professional expertise and personal commitment to drive visionary, impactful strategies. 
• Long-Term Commitment: They are in it for the long haul, committing to sustained impact across generations and prioritizing long-lasting solutions over short-term gains. 
• Collectivism: They embody the philosophy of "I am because we are," actively engaging in collaborative networks and fostering community-reflective solutions. 

The Clinical Data, Safety and Statistical Centers (CDSSC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance clinical research through comprehensive support. This includes statistical analysis, protocol development, and oversight of safety monitoring in studies related to asthma, autoimmune diseases, and transplantation. By coordinating these efforts, the program seeks to facilitate impactful research outcomes and improve public health outcomes through informed data-driven decisions.

The NINDS Alzheimer’s Disease-Related Dementias (ADRD) K99/R00 program promotes diversity by supporting new independent investigators from underrepresented backgrounds in AD/ADRD research. This award facilitates a transition from mentored postdoctoral positions to independent faculty roles, providing essential NIH research support. Applicants must propose research that does not involve leading a clinical trial but may include participation in trials led by mentors. Key deadlines for applications span from October 2024 to June 2027.