Best Unrestricted Grants for Nonprofits in Tennessee

Communities Foundation of Oklahoma

The Communities Foundation of Oklahoma stems from the vision of Tom McCasland Jr., and Gene Rainbolt. Two decades ago, these gentlemen formed a shared vision to create a single philanthropic organization to serve the charitable needs to rural communities across the great state of Oklahoma. Today, CFO has grown to assist hundreds of efforts in more than 45 counties.

At the Communities Foundation of Oklahoma, we believe in the power of connecting individuals, nonprofits, businesses, and communities. Because when passionate people are paired with purposes they care about most, the communities in Oklahoma will prosper. We aim to strategically distribute charitable funds, maximize our donors’ impact, and strengthen their communities through stewardship and commitment to sustainable change.

2027 Cherokee Nation Nursing Scholarship

The purpose of this scholarship is to provide financial assistance to Cherokee Nation students pursuing college degrees in nursing no matter the residence of the student. You must currently be enrolled in a bachelor's or master's program (no prerequisites). Payback period required upon program completion, in the Cherokee Nation Reservation. This application is for members of the Cherokee Nation ONLY.

The Ben J. Lipps Research Fellowship Program supports nephrology fellows in conducting original research on kidney biology and disease. Each fellow receives $50,000 annually for up to two years, with a limit of two applications per sponsor per cycle. Candidates must hold an MD, DO, PhD, or equivalent and commit to 75% research time. The program encourages applications from underrepresented minorities in medicine, fostering diversity in nephrology research.

The High-End Instrumentation (HEI) Grant Program, offered by the NIH, invites applications for purchasing or upgrading high-end, specialized instruments, with a minimum award of $750,001 and a maximum of $2,000,000. This program supports NIH investigators aiming to enhance their research capabilities through advanced technologies such as mass spectrometers and electron microscopes. Applications must be submitted by 5:00 pm local time of the applicant organization.

This grant aims to enhance cooperation and regulatory standards among animal food safety programs by funding national feed associations. It promotes inter-agency collaboration, strengthens state regulatory frameworks, and supports the Animal Feed Regulatory Program Standards (AFRPS). By leveraging resources and aligning with federal and state initiatives, the program seeks to improve animal food safety and ensure comprehensive surveillance and protection.

The NIH is seeking innovative computational approaches to enhance the curation of biomedical research assets at scale. This initiative aims to accelerate access to secure datasets and computational models, facilitating transformative discoveries in biomedical science. Key deadlines for applications range from January 2025 to January 2027, covering standard, renewal, and AIDS-related grants. Applicants are encouraged to submit Letters of Intent 30 days prior to application deadlines to ensure a streamlined review process.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is announcing a Notice of Funding Opportunity (NOFO) for Diabetes Research Centers (DRCs). These centers aim to foster collaboration among diabetes researchers, enhance preclinical and clinical research, and provide access to specialized resources. Emphasis is on innovative scientific themes and collaborative projects in areas such as Immunology and Artificial Intelligence. Although applications are not currently solicited, potential applicants are encouraged to prepare for future submissions.

Community Foundation of Henderson County

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Our Mission is to help people who care make lasting contributions to causes that matter. The Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

Bryce A. Malsbary (BAM) Scholarship

The purpose of the Fund is to provide a scholarship for a person seeking higher education at an accredited institution, including but not limited to: vocational, technical, trade, college, or university levels of education. Assistance is for a resident of Henderson County or Polk County, North Carolina, leading to a degree. Candidate must show financial need, GPA 3.0 or higher, and have community service, work, or school activities. Student must be a legal resident of North Carolina.

The Alzheimer’s Association Research Grant For All (AARGA) Program supports early-career investigators in their first seven years as independent researchers. This grant aims to fund projects that develop preliminary data and test new hypotheses in Alzheimer’s and related dementia research. Areas of interest include disease mechanisms, biomarker development, and health equity. Applications are welcome from both U.S. and international researchers, fostering innovation and collaboration in the fight against dementia.

The Nugent McGrew Scholarship, provided by the Central Kentucky Community Foundation, aims to support graduating seniors from Grayson or Hardin County who demonstrate financial need and a commitment to their education. Applicants must maintain a minimum GPA of 2.5 and plan to attend a two or four-year academic or technical school. This scholarship serves as a vital resource to help students achieve their educational goals and contribute positively to their communities.

The Patricia Goodman Memorial Scholarship, offered by the Central Kentucky Community Foundation, supports graduating high school seniors in the CKCF service area, prioritizing Hardin County residents. Applicants must maintain a minimum GPA of 2.75 and intend to pursue a career in nursing or a related medical field. This scholarship aims to empower future healthcare professionals while enriching community life through educational opportunities.

Community Foundation of Henderson County

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Our Mission is to help people who care make lasting contributions to causes that matter. The Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

Arthur and Lois Jean Stuenkel Scholarship

This scholarship provides financial support to a graduating senior seeking to further his or her education beyond high school. The recipient must be in the top 25% of his or her graduating class and demonstrate financial need. This scholarship is for a worthy student who has participated in sports or extracurricular activities. 

The scholarship is renewable.

The CLRA Research Grant Program, led by the Children’s Leukemia Research Association, focuses on funding innovative research aimed at uncovering the causes of leukemia and improving treatment options. Grants totaling $30,000 are awarded to U.S.-based researchers, with the intention of advancing scientific understanding and ultimately finding a cure. The program has made significant contributions to the high cure rates for childhood leukemia, showcasing the importance of continued research in this field.

About

What is FOXG1 Syndrome?

FOXG1 syndrome is a rare genetic neurodevelopmental disorder caused by a mutation in the FOXG1 gene. FOXG1 gene is one of the first and most important genes for early brain development and when impaired, causes developmental disabilities as well as medical complexities, including epilepsy.

Every child born with FOXG1 syndrome is unique as FOXG1 manifests as a spectrum where symptoms and severity vary between individuals. Our patient data shows characteristics of children with FOXG1 syndrome include: non-speaking, non-ambulatory, experience seizures, feeding problems, cortical vision impairment, movement disorders, and developmental delays. Less-severely-affected FOXG1 children often present with (ASD) Autism Spectrum Disorder as FOXG1 is an autism related gene. FOXG1 syndrome is found equally among both females and males and is geographically more prevalent where diagnostic testing is more advanced. 

Our Story & Mission

When our children were diagnosed with FOXG1 syndrome, we were told there was nothing we could do. No treatments, no concerted research underway, no roadmap. Just a devastating diagnosis for a disorder few had ever heard of.

But we refused to accept that. 

Research Assets & Grants

FOXG1 Scientific Research Project Grants

The FOXG1 Research Foundation is providing grants to scientists to deepen the understanding of the biology of FOXG1 with the goal of identifying innovative therapeutic strategies and finding a cure.

For the next few years, these are the strategic focus areas:

• Experiments designed to understand when, where, and levels of FOXG1 needed for normal brain development in mice
• Experiments designed to understand the biophysical properties of FOXG1 mutations
• Experiments designed to gain insights into the molecular and cell biological pathways regulated by FOXG1  

Retina Research Foundation

Across the nation, there were only a handful of voluntary groups with the will and the means to tackle retinal disdorders. Retina Research Foundation, established in 1969, was one of those organizations. By the 1980s, RRF had become a voice for retina research in an effort to reduce the incidence of retinal disease, which was fast becoming the leading cause of blindness in developing countries.

Undaunted, the Foundation steadily raised funds each year for vision scientists who were nationally recognized for their work in retina research. Government funding for eye research increased dramatically, and the field of retina research matured. As this body of knowledge grew, RRF programs were expanded to include major awards that recognize established retina scientists and contribute to their ongoing research. The Foundation also developed scientific exchange programs to disseminate knowledge of the dramatic advances that were being made in the laboratory.

RRF Pilot Study Grants

The mission of the Retina Research Foundation is to reduce retinal blindness worldwide by funding programs in research and education. As a public charity, RRF raises funds from the private sector and the investment of its endowment funds.

RRF is currently welcoming pilot study grant applications for the 2027 grant period. Each grant application must be signed by the principal investigator and either their Department Chair or Dean of Research.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention for patients with RUNX1 familial platelet disorder (RUNX1-FPD). This program supports interdisciplinary research teams investigating the mechanisms of leukemogenesis and innovative treatment strategies. With funding of up to $430,000 per year, LEAP encourages projects focused on both understanding clonal evolution and developing novel therapeutic approaches. The initiative seeks to bridge critical knowledge gaps and provide urgent interventions for high-risk populations.

The Fiscal Year 2026 Flood Mitigation Assistance program aims to enhance flood mitigation funding delivery, focusing on the needs of disaster survivors. This federal initiative, managed by FEMA, provides essential funds to states, territories, and local governments to mitigate flood risks and reduce repetitive damage to properties insured under the National Flood Insurance Program. The program supports various activities designed to lower the financial exposure of the NFIP while promoting community resilience against flooding.

About the Awards

The late Dr. James F. Fries, formerly professor emeritus of medicine at Stanford University, came up with the idea for the James and Sarah Fries Prize for Improving Health in a 1987 ascent of Nepal’s Makalu—one of the world’s highest peaks—when his party became trapped in a severe snowstorm and was ultimately unable to scale the mountain.

Following that experience, Dr. Fries returned to sea level and set about establishing a foundation to support a Nobel-like prize for health that now annually awards a $100,000 prize to an an outstanding leader judged by an expert panel to have done the greatest good for the greatest number of people in the field of health.

In 1992 the Elizabeth Fries Health Education Award was established in honor of Elizabeth Fries, daughter of James and Sarah Fries. The $50,000 prize is awarded annually to an individual judged to have made substantial contributions to their area of health education and health promotion. Sarah Fries remained active in the Fries Awards for Health program until her death in May 2017, and Jim Fries remained active in the awards until his death in November 2021.

The CDC Foundation is honored to partner with the James F. and Sarah T. Fries Foundation, which established and funds the award. As of 2016, the CDC Foundation manages and administers the Fries Awards for Health program, which include the James and Sarah Fries Prize for Improving Health and the Elizabeth Fries Health Education Award.

The Tennessee Department of Environment & Conservation offers competitive grants for municipalities to establish Household Hazardous Waste Collection Facilities (HHWCF). Eligible applicants include municipalities with populations over 100,000 and those meeting specific criteria under T.C.A. §68-211-828. Grants support the creation of permanent collection sites and temporary infrastructures. Eligible projects encompass safety equipment, signage, and operational reimbursements. Ineligible applicants include those with outstanding balances on previous grants. This initiative aligns with the state's solid waste management goals.

The Society of Toxicology offers the Supplemental Training for Education Program (STEP), which provides up to $1,000 to support graduate students in toxicology seeking additional training to address skill gaps. Eligible applicants must be PhD students who have completed coursework and passed comprehensive exams. The funding covers workshops or courses not available through their graduate program, enhancing career prospects in toxicology.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention strategies for patients with RUNX1 familial platelet disorder. This initiative, supported by the American Cancer Society, focuses on understanding the mechanisms behind leukemia development and fostering innovative research leading to effective treatment options. Grants of up to $215,000 per year for four years are available, emphasizing the urgent need for targeted therapies in high-risk populations.

The NCB - Botany Research Scholarship Program, offered by Northern California Botanists, targets undergraduate and graduate students pursuing research in botany and plant ecology. Scholarships of $1,500 support independent study, thesis, or dissertation projects within a specific geographic area of Northern California. Eligible applicants may reapply for funding for up to four years. This initiative aims to foster academic careers in botany and promote valuable ecological research.

Emand Hamad, M.D. Healthcare Career Scholarship

Provides scholarships to students planning on majoring in a healthcare major.

The Lipsky-Whittaker LGBTQ Scholarship, established by the SouthCoast Community Foundation, provides financial support to graduates from New Bedford area high schools who identify as LGBTQ+. Applicants must be under 24 years old and enrolled in or accepted to an accredited college. This scholarship aims to empower students committed to addressing LGBTQ+ issues in their communities, contributing to a more inclusive society.

Idaho Community Foundation

The Idaho Community Foundation distributes millions annually in grants and scholarships across the state. These awards are made possible by individuals, families, businesses, affiliates, giving circles, and everyday Idahoans who care for their community.Robert C. Weaver Memorial Scholarship FundEstablished by Neola Weaver in memory of her late husband, residents or former residents of Buhl are eligible for scholarship support as either traditional or nontraditional students. For part-time or full-time traditional or nontraditional students pursuing post high school vocational or academic training. 

The FY26 Reconstructive Transplant Research Program (RTRP) Investigator-Initiated Research Award supports innovative studies aimed at enhancing reconstructive transplant research and patient care. It emphasizes projects with military relevance, focusing on all research phases from basic to clinical. Essential components include rigorous study design, preliminary data, and the potential for significant short- and long-term impacts on patients and the reconstructive transplant field.

The Exhibitions Abroad Support Grant Program, initiated by the Japan Foundation in New York, offers financial aid to U.S. museums and art institutions organizing exhibitions that showcase Japanese art and culture internationally. This program supports a range of events, including biennials and triennials featuring Japanese artists. Eligible applicants are non-profit organizations from designated states, with a focus on promoting cultural exchange and understanding through art.

The NIMH Career Transition Award (K22) supports tenure-track intramural investigators at NIMH in their transition to independent research faculty positions. This program aims to foster innovative research in mental health, encouraging applicants with a strong record of research excellence. Key deadlines for applications vary, including those for standard and renewal submissions, emphasizing the importance of timely applications to secure funding and advance mental health research initiatives.