Best Grants for Nonprofit Healthcare Programs in Alabama

Alabama Rural Health Transformation Program: Maternal and Fetal Health Initiative

Program Overview

The Centers for Medicare and Medicaid Services (CMS) Rural Health Transformation (RHT) Program was authorized by Public Law 119-21 on July 4, 2025. The RHT Program is a $50 billion federal initiative planned to establish funding to strengthen rural hospitals and modernize the healthcare ecosystem for all 50 states. The RHT Program is designed to transform the rural healthcare ecosystem along five strategic axes: supporting rural health innovations, improving provider sustainability, developing the local healthcare workforce, expanding care delivery models, and testing technology-based solutions.

The Alabama Rural Health Transformation Program (ARHTP) is Alabama’s broader statewide framework for advancing the goals of the Rural Health Transformation (RHT) Program through coordinated, statedesigned strategies, initiatives, and investments intended to improve rural healthcare access, strengthen quality and delivery systems, support innovation, and promote long-term sustainability and accountability in rural communities. ARHTP is focused on transformational, practical approaches that strengthen provider networks, improve access to appropriate services closer to home, and support more resilient models of rural healthcare delivery across Alabama.

The Alabama Department of Economic and Community Affairs (ADECA), on behalf of the ARHTP, invites eligible applicants to apply for funding under the Maternal and Fetal Health Initiative. The purpose of this initiative is to improve maternal and fetal health outcomes in rural Alabama by addressing gaps in access to care and strengthening the capacity of healthcare systems to provide maternal and fetal health services. This includes connecting rural healthcare facilities to regional maternal and fetal referral hubs and expanding access to specialized imaging services and telerobotic ultrasound devices necessary to ensure healthcare facilities have the capacity, connectivity, and resources required to provide appropriate maternal and fetal care services. This NOFO establishes the application requirements, review framework, and award parameters for competitive funding designed to accomplish the purpose of the initiative as set forth above.

The Maternal and Fetal Health Initiative is intended to support practical, scalable strategies that strengthen maternal healthcare delivery systems across rural Alabama. Consistent with the State’s ARHTP framework, this initiative supports projects involving the establishment and enhancement of regional maternal and fetal referral hubs, the acquisition and deployment of telerobotic ultrasound equipment, and equipment upgrades and minor building renovations or alterations necessary to provide appropriate services under the defined strategy categories described below.

Projects funded under this NOFO must serve rural Alabama, align with at least one of the defined Maternal and Fetal Health Initiative strategy categories listed below, and clearly demonstrate how the proposed project advances one or more of the initiative goals identified in this section. Applicants do not need to be physically located in a rural area to apply; however, each proposal must clearly demonstrate that the project is specifically designed to provide a direct benefit to rural Alabama communities, expectant mothers, infants, healthcare providers, or facilities participating in regional referral networks.

Nonprofit organizations in Alabama providing health care access, basic needs, mental health services, or veterans programs can apply for operating grants up to US $25,000 from the Daniel Foundation of Alabama. Eligible 501(c)(3)s must be Alabama-based, under $5 million in revenue, with at least one paid employee and a qualifying 990 filing.

Nonprofit 501(c)(3) organizations and eligible governmental units providing healthcare access, basic human needs, or community betterment services in Alabama can apply for the Frankenmuth Insurance Foundation Charitable Grant. Funding supports programs such as health and wellness initiatives, affordable housing, food assistance, and related community services in states where Frankenmuth Insurance operates, including Alabama.

Cities and municipalities in Alabama with populations near or above 6,000 residents can apply for National League of Cities’ free Federal Grant Navigation Program to pursue ARPA and IIJA funding for local needs. Local governments working on health care access and delivery, housing, workforce, transportation, technology, education, and economic development may benefit.

Holle Family Foundation provides Alabama 501(c)(3) nonprofits with reimbursable grants for physical needs like equipment, transportation, repairs, and renovations that support vulnerable children, people with special needs, and those facing hunger or homelessness. Nonprofits improving health care access and related services in central Alabama counties may be especially competitive under its societal needs focus.

Nonprofit and faith-based 501(c)(3) organizations in Alabama can use this funding for health, human services, and energy assistance programs serving low-income residents. Grants from Alabama Power Foundation help Alabama healthcare access, wellness, and social service programs with projects open to the general public, offering up to US $500 per year per organization.

Nonprofit organizations in Alabama working on health care access, mental health, or education programs for adolescents, post-secondary students, or adult learners can apply for US $10,000 - US $75,000 in continuation or expansion funding. L B Research and Education Foundation supports U.S.-based 501(c)(3)s with $500,000–$10 million budgets, emphasizing underserved populations and evidence-informed approaches.

Nonprofit 501(c)(3) public charities running health and wellness, basic needs, or life-skills programs in Alabama can apply for support from Davison Bruce Foundation. The foundation funds disadvantaged and crisis-affected populations through health care access, wellness services, economic assistance, education, and Christian ministry, and may benefit nonprofit healthcare programs serving vulnerable communities.

Nonprofit 501(c)(3) organizations in Alabama can seek funding to expand health, wellness, and broader community programs that serve local residents. Grants from Cleveland Cliffs Foundation help healthcare and human service providers improve access to care, promote healthy lifestyles, and strengthen vibrant communities in areas where the company operates.

Nonprofit 501(c)(3) organizations in Alabama working in health care access and delivery can seek funding for capital projects or special initiatives that expand or strengthen services. Grants from James M Cox Foundation support health, early childhood education, conservation, and family empowerment in U.S. communities where Cox Enterprises operates, with applications reviewed three times annually.

First- and second-year medical students conducting health-related research in Alabama can receive US $7,000 for clinical, laboratory, epidemiology, health services, leadership, or professionalism projects through the Carolyn L. Kuckein Student Research Fellowship. Alabama healthcare-focused nonprofits hosting or mentoring eligible students may benefit from this Alpha Omega Alpha opportunity.

The NIHCM Foundation's Local Media Award honors outstanding local journalism that enhances understanding of health care issues in the U.S. It aims to recognize reports that improve health care affordability, accessibility, and quality. A $15,000 prize is awarded to the winner. Eligible entries must be published in 2025 and focus on local markets, offering insights relevant to health plans and policymakers. This award encourages innovative reporting that addresses the complexities of the health care system.

The NIHCM Foundation Investigative and General Reporting Award honors outstanding reporting that enhances understanding of U.S. health care affordability and quality. A $20,000 prize is awarded to the winner, with entries evaluated for quality, originality, and impact. Eligible submissions include stories published in 2025 from national outlets, focusing on insightful reporting that informs health care policymakers and consumers about rising costs and access solutions.

The NIHCM Foundation's Trade Journalism Award honors outstanding reporting aimed at specialty audiences, focusing on enhancing the affordability, accessibility, and quality of healthcare in the U.S. A $15,000 prize will be awarded to the winner. Entries, which can be individual stories or series published in 2025, must provide valuable insights relevant to health plans, policymakers, and stakeholders, addressing the critical issues of rising healthcare costs and access.

Wegmans Family Foundation Inc focuses on cultivating healthy communities through support for hunger relief, health initiatives, education, and youth programs. They prioritize collaborations with local nonprofits to enhance community well-being, offering assistance in key areas like economic mobility and youth engagement. Despite their wide-ranging support, they have specific ineligibility criteria, such as not accommodating personal requests or solicitation on their property, aiming to direct resources effectively where they are needed most.

The Will Rogers Motion Picture Pioneers Assistance Fund offers crucial financial support and counseling for individuals in the theatrical exhibition and distribution sectors facing health-related challenges. This fund assists with medical expenses, housing emergencies, and essential services like vocational rehabilitation and equipment aid. Eligible applicants must have a minimum of three years in exhibition or five years in distribution. The fund aims to provide a safety net for those impacted by illness, injury, or significant life changes.

Bristol Myers Squibb Foundation Inc supports independent medical education to enhance healthcare professional competence and improve patient health outcomes. Their mission is to be a global leader in innovative medical education, focusing on evidence-based activities that address critical gaps in knowledge. By fostering excellence in healthcare, they aim to ensure measurable improvements in performance and patient outcomes across various disease areas.

West Pharmaceutical Services, Inc. offers the WPS Community Support Grants & Sponsorships, emphasizing a culture of giving and community involvement. The program supports 501(c)3 organizations that address healthcare challenges and focus on children, disabled individuals, and STEM education. Through financial support and volunteerism, West aims to foster healthier communities where its employees live and work, reinforcing its commitment to philanthropy and social responsibility.

The NIHCM Foundation's Policy Research Award honors outstanding research published in peer-reviewed journals that significantly contributes to improving the affordability, accessibility, and quality of healthcare in the U.S. The winner will receive a $20,000 prize. Eligible entries must address healthcare affordability and be published in 2025, with a maximum of three submissions per author. This award aims to recognize innovative insights that can inform policymakers and stakeholders in the healthcare sector.

The NIHCM Foundation's Television and Audio Journalism Award honors outstanding television and audio reporting that contributes to enhancing the affordability, accessibility, and quality of healthcare in the U.S. With a prize of $20,000, the award seeks entries that showcase creativity and originality while providing new insights relevant to health plans, policymakers, and consumers. Eligible entries include stories broadcasted in 2025, focusing on critical healthcare issues.

The Excellence in Medicine Awards, presented by the AMA Foundation, honor exemplary physicians and medical advocates committed to volunteerism, community engagement, and leadership. Since 2005, this prestigious program has celebrated over 100 honorees, recognizing their vital contributions to underserved populations. Awardees receive a $2,500 grant honorarium to support a nonprofit health organization of their choice, collectively awarding over $250,000 to enhance community health and promote equitable care across the nation.

At Genentech, we invest in bold ideas and innovative solutions that address systemic inequities in science and medicine to advance a more just healthcare system. We focus on efforts that diversify the scientific and medical workforce, advance health equity, and help our communities thrive. We also further advance excellence in medicine and healthcare through our grants for independent medical education. Including efforts to advance health equity, support patient needs, engage the scientific community, and provide co-pay assistance. 

There are multiple ways to apply for funding. Before you submit an application, we encourage you to explore the following materials to learn more about our opportunities for funding, eligibility requirements and considerations, and the process for submitting a proposal within our Funding Request System (gFRS).

The GoodRx Helps Community Catalyst Grants support community-led nonprofits dedicated to enhancing health and well-being for under-resourced groups. This funding aims to improve healthcare access, education, and essential services, addressing systemic barriers faced by these communities. Eligible organizations must demonstrate a commitment to community empowerment and possess a minimum annual operating budget of $250K. This initiative underscores the importance of fostering sustainable health improvements through targeted, inclusive support.

Mission

To empower worthy nonprofits by providing critically needed, unrestricted funding that helps them fulfill their missions with confidence and sustainability.

How We Serve Nonprofits

AmFund partners with nearly 800 organizations annually—supporting causes related to health, education, the arts, human services, animal welfare, and more. We’re known for our:

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Our model is built on relationship, trust, and results. Every trip sold, every service provided, and every donor interaction is designed to maximize your fundraising impact—without adding burden to your team.

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The Middle Run Foundation is a family-governed foundation based in Newark, Delaware. The Board of the foundation is chaired by Sarah Ives Gore, its founder, and includes her children, grandchildren, and non-family members who bring experience and expertise to our work.

About

Purpose:

The purpose of the foundation is to fund and support non-profit programs which focus on building healthy, self-sufficient families.

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The Middle Run Foundation makes grants up to $500,000 annually with individual grants ranging from $5,000 to $50,000.

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Response & Emergency Needs Fund

The NAFC Response & Emergency Needs Fund is designed to address urgent and unforeseen challenges that threaten operations or patient access to care within NAFC member organizations. These organizations often operate with limited reserves, making them especially vulnerable to unexpected repairs, equipment failures, workforce disruptions, or community emergencies. This fund provides rapid, flexible support to help stabilize operations and ensure continuity of care for uninsured and underserved patients.

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Healthcare Services Expansion Fund

The NAFC Healthcare Services Expansion Fund supports the launch or expansion of clinical programs and new service areas that increase access to care for underserved patients. This funding is designed to help NAFC members introduce new services or grow existing programs that address unmet community health needs and improve access to comprehensive, patient-centered care.