Best Unrestricted Grants for Nonprofits in Virgin Islands

The OVC FY 2026 Services for Victims of Human Trafficking aims to enhance victim service programs across the United States. This initiative supports victims by providing critical services to address their diverse needs, including mental health support and assistance with legal challenges. By funding comprehensive programs, the Office for Victims of Crime seeks to combat human trafficking effectively and promote recovery for affected individuals, ensuring their rights and well-being are prioritized.

The Feasibility Clinical Trials of Mind and Body Interventions (R34) program seeks to support trials focused on complementary health approaches for conditions identified as high-priority by NCCIH. This funding opportunity aims to gather essential data necessary for planning future clinical efficacy studies. Applicants must demonstrate the feasibility of interventions and their potential impact on public health. Contacting NCCIH scientific contacts before submission is encouraged, and a Plan for Enhancing Diverse Perspectives is required.

The NIH Director's New Innovator Award supports creative early-stage investigators pursuing innovative research with transformative potential for science relevant to the NIH mission. Applications are encouraged across all NIH-related fields, enhancing support for emerging talent. This award is part of the NIH Common Fund's High-Risk, High-Reward Research Program, which aims to cultivate groundbreaking research and foster the next generation of scientists.

The National Institute of Environmental Health Sciences (NIEHS) is launching a funding opportunity for research hubs focused on the health impacts of extreme weather. This initiative encourages multidisciplinary teams to engage with community partners on issues such as wildfire smoke and extreme heat. Emphasizing collaboration, the program aims to develop scalable solutions and measurable public health outcomes, leveraging resources and expertise across institutions to address climate-related health challenges effectively.

The National Endowment for the Humanities invites K-12 teachers and higher education faculty to apply for the Landmarks of American History and Culture and Summer Institutes program. This initiative aims to enhance humanities education through professional development opportunities, fostering a deeper understanding of historical and cultural landmarks. Participants will engage in enriching experiences designed to improve teaching practices and student learning outcomes in the humanities.

The FY 2027 Service Area Competition (SAC) funding aims to enhance healthcare access in underserved communities across the U.S. by providing grants for comprehensive primary and preventive health services. This initiative addresses essential health needs through competitive funding opportunities, ensuring that health centers can effectively serve their designated areas. Additional service areas may be announced as needed if current centers are unable to continue their operations, thus maintaining service continuity.

The NIOSH National Center of Excellence for the Prevention of Childhood Agricultural Injury (U54) aims to enhance the safety and well-being of youth in the agriculture sector. This initiative will conduct vital research, improve data collection, and implement effective interventions to mitigate risks faced by young workers. By collaborating with various stakeholders, the center seeks to translate scientific findings into practical solutions that promote healthier working environments for children in agriculture, forestry, and fishing industries.

The NIH Research Software Engineer (RSE) Award aims to provide salary support for outstanding Research Software Engineers who play a vital role in creating and sharing biomedical, behavioral, or health-related software and tools. This opportunity encourages RSEs to enhance the development of algorithms and support training for prospective users. Applications are due by 5:00 PM local time, with optional Letters of Intent recommended 30 days prior to the proposal deadline.

The Lewis-Houghton Civics and Democracy Initiative, under the Teaching with Primary Sources program, aims to empower organizations in the U.S. and its territories to create innovative projects that leverage digitized primary sources from the Library of Congress. This initiative, named after Reps. Lewis and Houghton, promotes education in civics, democracy, and history, fostering critical thinking and literacy among students. Grants will be awarded based on the proposal's alignment with these educational goals, enhancing community engagement.

The Rural Health Value Program aims to fund one recipient to provide essential analysis and technical assistance for rural stakeholders. This initiative helps them navigate the value-based care landscape in rural healthcare settings. By supporting rural providers, the program seeks to enhance their participation and success in innovative payment and delivery models that emphasize quality care and value-driven strategies. This funding opportunity ultimately aims to strengthen rural healthcare systems.

The Veterans Legacy Grants Program (VLGP) offers funding up to $400,000 to eligible entities for cemetery research related to Veterans’ interred in national, State, or Tribal cemeteries. It aims to create educational materials promoting community engagement and understanding of Veterans' histories. Administered by the Department of Veterans Affairs, the program provides resources for educational institutions to enhance public knowledge and appreciation of Veterans’ contributions and legacies.

PetSmart Charities' Adoption Prep Grants aim to support organizations that facilitate the adoption of homeless pets through in-store programs. Eligible partners must demonstrate a commitment to increasing adoptions, with grants reaching up to $75,000 in the U.S. and $40,000 in Canada. The funding can be utilized for vaccinations, spay/neuter services, staffing, and volunteer support. This initiative focuses on building sustainable adoption programs that break down barriers to pet adoption.

The Gerber Foundation offers grants for pediatric research focusing on environmental hazards that affect infants and young children. The foundation seeks projects that provide innovative solutions to health and nutritional challenges faced by this vulnerable population. Grant applications are encouraged from organizations recognized as tax-exempt under Internal Revenue Code 501(c)(3), with an emphasis on research that produces new information to improve practices in infant care and development.

The Teiger Foundation Programming Grant supports innovative visual arts projects led by curators at smaller non-profit organizations with budgets under $3.5 million. Grants of up to $150,000 are available for three years, funding development, realization, and documentation of exhibitions and related programs. The foundation emphasizes community engagement, racial justice, and artistic experimentation while encouraging collaboration with other cultural institutions. Note: The next Call for Proposals opens in Fall 2026.

The Teiger Foundation's Hosting Grant provides up to $75,000 for US-based curators or artistic directors to present contemporary visual art exhibitions that originated in different contexts. This grant encourages resource-sharing and collective learning, allowing institutions to expand their programming sustainably. It prioritizes projects affiliated with established non-profits, fostering community-building and positive change in the field of visual art while addressing issues of racial justice and climate crisis.

The Teiger Foundation's Curatorial Research and Development Grant offers support for innovative curatorial practices within the contemporary visual arts sector. Designed to address gaps in funding, this grant provides up to $50,000 for curatorial research projects, including travel and collaborative investigations. It emphasizes the importance of experimentation and creativity while aligning with values of racial justice and environmental sustainability. The next Call for Proposals will open in Fall 2026, with funding opportunities available to U.S.-based curators.

The National Urban Indian Health Program aims to enhance behavioral health services for Urban Indian communities by fostering awareness, advocacy, and collaboration across the nation. By providing technical assistance and training to Urban Indian Organizations, the program seeks to improve access to culturally relevant behavioral health care for American Indian and Alaska Native populations residing in urban areas, ultimately leading to better health outcomes and community support.

The Higher Education Challenge Grants Program, managed by the USDA's National Institute of Food and Agriculture, aims to enhance institutional capacities in food and agricultural sciences education. This initiative focuses on improving curriculum, faculty, and student recruitment for master's and doctoral programs, particularly in veterinary medicine. By strengthening these educational frameworks, the program seeks to ensure the availability of skilled professionals in critical agricultural sectors.

The Institute of Education Sciences (IES) offers a grant to support state education agencies in utilizing longitudinal data systems to inform policies and programs for learners with disabilities. This initiative aims to enhance evidence-based decision-making at both state and local levels, ensuring better educational outcomes for at-risk students. The grant encourages collaboration and effective use of data to promote informed policymaking in special education.

The NIH Common Fund Data Ecosystem aims to enhance the reusability of biomedical data through collaboration between Common Fund programs and external data resources. This funding opportunity encourages projects that connect various biomedical data ecosystems, including the HEAL Data Ecosystem and the BRAIN Initiative. By fostering partnerships, the initiative seeks to improve the accessibility and interoperability of valuable datasets, ultimately advancing research efforts. Note that clinical trials are excluded from this funding opportunity.

Museums Empowered (2027) is a professional development initiative by the Institute of Museum and Library Services aimed at enhancing museum staff capabilities. It focuses on three vital areas: digital technology, evaluation, and organizational management. By supporting training and learning opportunities, the program seeks to empower museum professionals to effectively utilize digital tools, improve evaluation methods, and strengthen organizational resilience, ultimately fostering growth within museums of all types.

The R21 Clinical Trial Not Allowed funding opportunity invites innovative research to develop and enhance research models and biological materials vital for studying human health and diseases. It emphasizes the need for new approach methodologies (NAMs) to improve the identification of confounding factors in biomedical research. Projects should have broad applicability across multiple NIH Institutes, focusing on various body systems and disease categories, ensuring relevance to a wide range of health issues.

The Disaster Distress Helpline (DDH) offers 24/7 crisis counseling to individuals in the U.S. and its territories facing emotional distress from disasters. Managed by SAMHSA, the helpline aims to enhance and strengthen access to crucial support services year-round, ensuring that those affected by natural or human-caused disasters receive the help they need to mitigate behavioral health impacts.

The National Institute on Deafness and Other Communication Disorders (NIDCD) and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) are seeking innovative research applications for non-invasive imaging technologies to study the human olfactory system. This initiative emphasizes the need for advanced multimodal imaging techniques to enhance diagnostic capabilities for olfactory disorders, addressing challenges posed by the system's unique anatomical features. Collaboration among experts is encouraged to foster impactful research developments.

The AAUW Community Action Grants provide up to $75,000 to support nonprofits and educational institutions that empower girls in grades K–12 to succeed in STEM fields. By fostering hands-on learning, mentorship, and family involvement, these grants aim to build confidence and skills among girls, especially those from underrepresented communities. AAUW believes that immersive STEM environments and relatable role models can inspire lasting interest and help close the gender gap in leadership and careers.

The CTIA Wireless Foundation's Catalyst Grant Program aims to empower social entrepreneurs leveraging 5G technology to tackle critical challenges in American communities. With over $200,000 in unrestricted grants available, the program supports innovative projects that utilize 5G connectivity for social good. As 5G transforms communication and interaction, the Catalyst Grant seeks visionary leaders who can harness this potential to inspire meaningful change and enhance community engagement.

The American Cancer Society (ACS) and the American Society for Radiation Oncology (ASTRO) co-fund the Clinician Scientist Development Grant (CSDG), aimed at advancing the research careers of clinician scientists in radiation oncology. Eligible applicants are full-time faculty members at U.S. institutions with a doctoral degree and an active clinical license. The grant supports research for 3 to 5 years, providing $135,000 annually for direct costs, plus allowable indirect costs, while encouraging diversity in applications.