Best Large Grants for Nonprofit Organizations in Virginia

The James B and Lois R Archer Charitable Foundation offers Large Grants for requests exceeding $10,000. Focused on fostering positive change, the foundation supports initiatives in Arts and Culture, Civic Engagement, Education, Health, and Human Services. Eligibility includes 501(c)(3) organizations, while restrictions apply to consecutive grant cycles and non-qualifying purposes such as endowments and fundraising events. Organizations are encouraged to apply for various projects to enhance community well-being.

The James B and Lois R Archer Charitable Foundation offers Smaller Grants of $10,000 or less to support initiatives in Arts and Culture, Civic Engagement, Education, Health, and Human Services. Organizations must have 501(c)(3) status and comply with eligibility criteria, including a one-year waiting period for reapplications. The foundation aims to have a significant impact on communities, especially in West Texas, while avoiding funding for specific exclusions such as endowments and fundraising events.

The Scott R. MacKenzie Foundation offers grants to support innovative genetic research aimed at advancing cures for diseases like cancer, diabetes, lung, and heart diseases. Only U.S.-based tax-exempt organizations with over five years of operation can apply. The Foundation emphasizes collaboration among research entities to enhance genome sequencing and disease detection. By funding these initiatives, they aim to foster awareness and progress in genetic research for future generations.

The Duff McDuff Green, Jr. Fund supports nonprofit organizations in Planning District 16, focusing on recreation, youth development, and cultural preservation. Grants are available for projects promoting outdoor activities, improving youth quality of life, and conserving local historical artifacts. Eligible applicants are tax-exempt nonprofits. The fund aims to foster community engagement while addressing pressing local needs. Funding requests over $7,500 are considered for impactful initiatives that align with these priorities, enhancing the region's cultural and recreational landscape.

The Robert J. Keown Trust, established in 1934, provides financial assistance to needy Christians through grants to charitable organizations. Managed by Wells Fargo Bank N.A., the trust focuses on supporting organizations that benefit residents of Los Angeles County. Eligible organizations must be 501(c)(3) exempt. Preference is given to requests aiding needy Christians and elderly women. The trust awards an average of four grants per year, fostering community support and outreach.

The Clark Memorial Fund Grant provides essential healthcare assistance to needy and indigent residents of Halifax County, Virginia. Established in memory of Elise Thomson Clark, the fund aims to defray hospitalization costs and support medical services for those in need. With an average grant size ranging from $3,000 to $5,000 and approximately 10 grants awarded annually, the fund emphasizes its commitment to improving health outcomes in the community. Applications are welcomed year-round.

The Undergraduate Development Program Student Travel Award offers undergraduate science majors a unique opportunity to attend the Society of Toxicology Annual Meeting from March 21–23, 2026. The program aims to inspire students pursuing research careers in toxicology and related biomedical sciences. Participants will engage with professionals, attend sessions, and explore various educational and career paths. SOT emphasizes inclusiveness, encouraging diverse perspectives to enhance innovation in the field.

The Joan M. Wismer Foundation, established in 2001, honors the legacy of Joan Marilynn Wismer, who was dedicated to charitable work and community service. The foundation focuses on improving lives through education, youth development, safety, humanitarian services, and medical research. It primarily supports IRS-recognized 501(c)(3) organizations, schools, and churches, while emphasizing the importance of sustainable funding and effective financial management in its grant-making process.

The Melanoma Research Alliance is offering the Exchange Patient Forum Scholarship for 2026, aimed at melanoma patients, survivors, and caregivers. This scholarship includes travel support for attending a one-day forum in Washington, DC, designed to empower participants with the latest research and treatment insights. The event fosters connections within the melanoma community, featuring networking opportunities and collaboration with leading experts, ensuring participants leave with valuable knowledge and support.

The Blue Mountain Community Foundation Common Scholarship supports current high school seniors and graduates from Walla Walla, Columbia, Garfield, or Umatilla County who have been residents for at least three consecutive years. It also includes adults residing in these counties and those working in the wine industry or pursuing degrees at the University of Idaho or WSU. This scholarship simplifies the application process by allowing students to apply once for multiple scholarships.

Fund the Dream Scholarship

The Fund the Dream Scholarship Fund was established in 2022 by the Hispanic Alliance, GA. The purpose of this scholarship is to ‘Build the Dream, One Graduate at a Time.’ Minority students from first-generation/low-income backgrounds face systemic roadblocks while navigating the college admissions process. Graduating seniors coming from low-income families are seven times more likely to drop out than those from families with higher income. In addition, 74% of Latino students enrolled in colleges and universities in the U.S. cut their education short due to the financial pressures of supporting their families. To help mitigate the educational opportunity gap and student debt crisis, the Hispanic Alliance Georgia Fund the Dream Scholarship will support one student who has huge aspirations for their life and is willing to work through anything to achieve them. This scholarship is funded by proceeds from the annual Latino Fest in Gainesville, Georgia and is part of our commitment to making academic and scholarship support more accessible for all students.

When choosing a recipient, the selection committee will take into consideration factors such as the applicant’s academic achievement, financial need, immigration status, volunteering efforts, future educational goals, and responses to essay question. Special consideration will be given to students participating in the Latino Youth Leadership Academy. The 2026 scholarship will be a one-time award of $1,500.

The Innovation Grants to Nurture Initial Translational Efforts (IGNITE) program, supported by the National Institutes of Health, aims to fund pharmacodynamic and pharmacokinetic studies. These studies will assess the biological activity of therapeutic agents, including small molecules and biologics, for diseases prioritized by participating institutes. The initiative emphasizes the development of non-opioid analgesics with minimal addiction risks. Although applications are not currently solicited, this notice encourages potential applicants to prepare collaborative projects.

The Student Research Grant in Audiology, offered by the American Speech-Language-Hearing Foundation, supports doctoral students conducting research in clinical and rehabilitative audiology. Up to three grants of $2,000 each are available for eligible students enrolled in accredited programs in the U.S. This initiative honors the legacies of Ira Ventry and Brad Friedrich, who made significant contributions to the field of audiology. Interested candidates must submit proposals for research projects to be initiated in this vital area.

The Gloria Anderson Memorial Scholarship, administered by the Community Foundation of the Northern Alleghenies, honors a beloved music teacher and the founder of the Singing Dutchmen Men’s Chorus. This scholarship, amounting to approximately $1,000, is available to high school seniors pursuing degrees in music education or performance, particularly those from areas served by the Singing Dutchmen. It reflects the Foundation's commitment to supporting local students in their educational endeavors.

The Ruth E. Reed Nursing Scholarship, established by the Community Foundation of the Northern Alleghenies, honors the legacy of Ruth Reed, a dedicated nurse. This scholarship supports students from Elk, Warren, and Clearfield Counties pursuing nursing degrees, with a GPA requirement of 2.5 or higher. With an annual award of approximately $500, it encourages future generations to pursue careers in nursing while recognizing the importance of continued education in healthcare.

About Us

The Elk County Community Foundation was started in the late 1990’s by a group of business and civic leaders, with the support of the Stackpole-Hall Foundation, who recognized the need for creating a perpetual funding stream to support Elk County—now and in the future. The Foundation was incorporated in 2000 and a year later was classified as a 501(c)(3) nonprofit organization.

The Foundation provides donors with a simple but powerful and highly personal approach to achieving their philanthropic goals while enhancing the quality of life for the people of Elk County.

The Community Foundation makes it easy for individuals, businesses, and organizations to establish a scholarship fund. Your fund can be created in as little as one meeting, with a short fund agreement, and a single gift. Or your fund can be set up with an initial gift that is added to in the future. We manage all the administrative details of your fund for you.

By establishing a uniquely-named scholarship, you have the ability to designate eligibility requirements including education level, the field of study, geographic area, etc. Many scholarships are established to honor parents, a family member, or someone who influenced your life.

Most scholarship funds at the Foundation are permanent endowments, with the annual earnings used to provide the scholarships

Tyler Bender EMS Scholarship Fund

Tyler Bender recently graduated from the Center for Emergency Medicine, and he felt compelled to give back by starting this scholarship to encourage other individuals to consider the EMS field. There is a constant demand for well-trained and qualified EMS professionals. Tyler hopes that this scholarship fund will help attract individuals to the field and alleviate a shortage of EMS personnel.

Amount: $500 annually

The Henry D. and Ruth G. Swartz Family Fund Scholarship, established in 1996, supports high school seniors from North Ottawa County pursuing post-secondary education in engineering, computer science, pre-law, or medicine. Awarded competitively by the Grand Haven Area Community Foundation, applicants must demonstrate financial need and provide necessary documentation, including transcripts and recommendation letters. This scholarship honors the legacy of local residents Hank and Ruth Swartz, encouraging students to achieve their educational goals.

The American Academy of Audiology offers the Investigator Research Grant to promote essential research in audiology and balance health care. With a funding limit of $20,000 for one-year projects, the grant aims to support innovative research that enhances the evaluation and management of hearing and balance disorders. Eligible applicants must hold a doctoral degree in audiology or hearing science and be affiliated with a non-profit institution in the U.S. or Canada, fostering collaboration between academia and clinical practice.

The H. Wayne VanAgtmael Cosmetology Scholarship, established in 2005 by Wayne Van Agtmael's family, honors his legacy in the cosmetology field. This scholarship supports high school graduates from the Tri-Cities pursuing a cosmetology degree, focusing on financial need and academic achievement. Applicants must provide transcripts and additional required documents. The scholarship aims to empower students, particularly those who are the first in their families to succeed beyond high school, in their educational journeys.

The Innovation Award by the American Lung Association offers $75,000 annually for up to two years, aimed at supporting promising investigators in lung disease research. With a legacy of over 120 years, the Association seeks to fund innovative projects that can significantly impact lung health. Eligible candidates must demonstrate prior excellence in their careers and have held a K or R type award within the last three to five years. This initiative fosters groundbreaking advancements in lung disease science.

The James W. Junior and Jane T. Brown Scholarship, established by Jane and James Brown in 2006, offers financial support to adult students over 21 in the Tri-Cities. This scholarship aims to ease the financial burdens faced by those returning to education. Applicants must demonstrate financial need and provide necessary documentation, including transcripts and a Student Aid Report. The program encourages recipients to assist others in their educational journeys, fostering a cycle of support in the community.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a graduating senior who has demonstrated the qualities of honesty, care, trustworthiness, and personal integrity, and who is active in sports and shows an interest in working with children or the elderly.

The Catalyst Award, offered by the American Lung Association, supports innovative research on lung disease and biology. This mentored grant provides $50,000 annually for up to two years, prioritizing novel projects with collaborative training plans. The American Lung Association aims to improve lung health and prevent diseases through research, education, and advocacy, focusing on defeating lung cancer and fostering a tobacco-free future.

The Michael Herman Scholarship, established by the Grand Haven Area Community Foundation, honors a talented young soccer player who passed away tragically at 15. This scholarship is awarded to graduating high school seniors from the Tri-Cities area who have played soccer and wish to continue participating in college-level soccer. Financial need is not a priority, and all eligible students are encouraged to apply for this opportunity to further their education while pursuing their passion for sports.

We administer a number of scholarships, which range from the traditional academic and athletic awards to corporate and special circumstances offerings. These scholarships are open to all residents of Marshall County, as long as other requirements are met.

Applying for a scholarship is free, so we invite you to spend some time finding opportunities for which you are a good fit.

Tony Ross Memorial Scholarship

The purpose of this fund is to provide one or more annual scholarships to graduating high school seniors who are residents or are attending schools in either Marshall County, Indiana or Starke County, Indiana who are pursuing a career in broadcasting.

This scholarship may be renewable to previous recipients.

Beckley Area Foundation

Beckley Area Foundation was established in January 1985 by ten community-minded citizens. It began with a gift of $1.1 million from the Dr. Thomas Walker Memorial Health Foundation as “seed” money for this Raleigh County project. BAF assets have grown to over $70 million with over 500 different funds managed by our three trustee banks. Today, Beckley Area Foundation is one of West Virginia’s largest community foundations.

Since its inception, BAF has distributed over $23 million to charities and other worthy projects in the fields of education, public recreation, health & human services, the arts, animal services and beautification.

Scholarships

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

Most of these scholarships must be awarded to students from our geographic area or at least preference given to such students. While the majority of scholarships benefit Raleigh County applicants there are others designated for Fayette, Summers, Webster, and Wyoming students. 

The File Girls Cystic Fibrosis Scholarship

Weighted for educational merit, personal achievement and financial need; West Virginia high school matriculating senior with a confirmed diagnosis of Cystic Fibrosis. Recipient will provide physician’s letter affirming a diagnosis of Cystic Fibrosis as part of the application process; The scholarship is to be awarded for post-secondary education through college, vocational or technical schools.

This scholarship is renewable.

TryMarine Grant

The Reservoir Fish Habitat Partnership (RFHP) is seeking candidate pilot sites for evaluating two water quality treatment technologies—TryMarine and Oase Water Technology—in small urban fishing lakes (1–3 acres).

Urban fishing lakes are important community resources, providing accessible angling opportunities and supporting local outdoor recreation. Many of these lakes experience nutrient‑driven water quality impairments such as algal blooms, low dissolved oxygen, and reduced water clarity. These issues degrade fish habitat and diminish angler satisfaction.

This pilot initiative aims to identify lakes where these technologies can be tested to determine their effectiveness, feasibility, and potential for broader application across the RFHP network.

Objectives

Water Quality & Habitat Objectives

• Reduce nutrient concentrations (total phosphorus, total nitrogen).
• Improve water clarity and reduce turbidity.
• Reduce harmful algal blooms (HABs).
• Increase dissolved oxygen stability to support sportfish populations.
• Improve habitat conditions for stocked and naturally occurring fish species.
• Reduce internal nutrient loading from sediments.

RFHP Program Objectives

• Demonstrate scalable tools for improving fish habitat in small urban lakes.
• Support community‑based fisheries enhancement.
• Provide case studies and data for future RFHP guidance.
• Strengthen partnerships among agencies, municipalities, NGOs, and angling groups.