Best Large Grants for Nonprofit Organizations in Wisconsin

The Bruce Krier Charitable Foundation Inc. offers Education Program Grants focused on enhancing educational opportunities in Sheboygan and Ozaukee Counties, Wisconsin. The foundation provides matching grants, scholarships, and support to local educational institutions, including St. Marcus Lutheran School and Marquette University. Eligible applicants must be 501(c)(3) organizations, and grants are aimed at projects that improve educational access and quality for children. The foundation prioritizes funding that completes projects over those that initiate new ones.

The National Cancer Institute (NCI) invites applications for transformative research in cancer biology and oncology through nanotechnology. This funding opportunity aims to address significant challenges by exploring the interactions of nanomaterials with biological systems. Projects should focus on utilizing nanoparticles and devices for targeted cancer therapies and enhancing diagnostic capabilities. Successful proposals will contribute to the foundational knowledge necessary for future nanotechnology-based interventions in cancer treatment.

The Asian Cultural Council (ACC) offers Organization Grants to arts and culture organizations in Asia and the U.S., promoting cultural exchange through travel and collaborative activities. These grants support immersive experiences, research, and access to artistic communities, fostering international dialogue and relationship-building. Organizations must be nonprofit or educational institutions, legally registered in eligible regions, and demonstrate a minimum of five years of relevant programming. ACC provides additional support to enhance project feasibility.

Scholarships are available to graduating high school seniors. Applications are accepted from mid-November until mid-March. Scholarship award recipients will be announced at the high school awards ceremony. 

Beatrice Reynolds Memorial Scholarship

Established by the late Ira T. Reynolds in memory of his late wife to assist a Susquehanna Community School District graduate who will major in education or teacher training. Scholarship is provided in four equal installments as long as the recipient remains a student in good standing.

The Radiation Exposure Screening and Education Program aims to support organizations in their efforts to screen and educate individuals who have been exposed to radiation from uranium mining and U.S. nuclear weapons testing. This initiative emphasizes the importance of awareness and education in mitigating health risks associated with radiation exposure, ensuring affected communities receive the necessary resources and support for health management.

The Chan Zuckerberg Initiative is calling for transformative research proposals through the Advancing Technologies for Spatiotemporal Omics in Live Tissue program. This initiative seeks to combine innovative engineering with biological research to explore the complex molecular dynamics of health and disease. By fostering collaboration among scientists and AI experts, this funding aims to unlock new high-precision interventions, significantly advancing our understanding and management of health issues.

The Smart Growth Grants program, managed by the National Association of Realtors, aims to enhance community development through educational initiatives aligned with Smart Growth Principles. Available in three levels, the grants support REALTOR Associations in promoting sustainable land use, community planning, and stakeholder engagement. Maximum awards range from $3,000 to $15,000, depending on the grant level. Note that the program is currently not accepting applications for 2025 and will reopen in January 2026.

The ACI Foundation's Tribute to the Founders Fellowship supports graduate students in construction, design, education, or materials. Awardees receive a $10,000 educational stipend, recognition in Concrete International magazine, and travel expenses to two ACI conventions. This fellowship aims to foster the next generation of concrete industry leaders through education and mentorship, while also encouraging personal development and career readiness through a structured internship program.

The J.M. Heberlig/B.J. Helterbran Scholarship Fund, established by dedicated educators, supports Pennsylvania residents pursuing degrees in Art Education or Recreation & Parks. This scholarship aims to alleviate the financial burden on students entering their second, third, or fourth year at a 4-year institution. With a focus on academic achievement, a minimum GPA of 2.8 overall and 3.0 in the major is required, alongside a demonstrated commitment to education and community service.

The Ralph J. Torraco Scholarship for Computer Science Studies, awarded by the UNICO Foundation, offers four scholarships of $1,000 each to full-time students pursuing a degree in Computer Science at accredited U.S. colleges. Eligible applicants must reside in specific states or have a UNICO sponsor, be U.S. citizens aged 18 or older, and continue their studies in the 2026-2027 academic year. Preference is given to those demonstrating financial need.

The Digital Wish Donation Program, initiated by Mobile Beacon, aims to provide affordable high-speed Internet access to K-12 schools, colleges, and libraries. For just $10 a month, participating institutions can receive donated mobile hotspots and discounted tablets, enabling them to enhance digital literacy and connectivity among underserved students. This initiative not only breaks down barriers to access but also fosters educational equality, ensuring that all learners have the tools they need to succeed in the digital age.

The All of Us Research Program seeks to advance its mission by enabling access to biospecimens stored in the All of Us supported Biobank for researchers to conduct assays to evaluate associations between biomarkers and chronic diseases and add data to the All of Us resource for broad use by researchers. Biomarker analysis includes, but is not limited to, biomarker discovery; biomarker validation; novel disease stratification; and multiomics integration for disease risk, diagnosis, and prognosis, in support of advancing precision medicine. The All of Us Research Program is a historic effort to enroll 1 million participants who share data to accelerate research and medical breakthroughs, and enable individualized prevention, treatment, and care. Researchers use data from the program to learn more about how individual differences in lifestyle, environment, and genetics can influence health and disease.Grant authorities that allow the All of Us Research Program to forecast this opportunity are as follows: 42 USC 241 and 284.

The Presbyterian Committee on the Self-Development of People Grant supports partnerships with economically disadvantaged groups in the U.S. It aims to empower these communities to take control of their lives and address systemic issues of poverty and oppression. This initiative encourages sustainable change through community-led programs that advocate for justice, human dignity, and economic equity, fostering a transformative impact on their local environments.

The Greenwall Foundation invites nominations for the 2025 Bernard Lo, MD Award in Bioethics, a prestigious $25,000 prize recognizing outstanding contributions to bioethics. This award highlights exceptional mentorship in bioethics, celebrating individuals who support rising professionals across diverse sectors, including academia, government, and public health. Nominations can be made by mentees and colleagues, fostering an inclusive recognition of mentorship excellence. Renominations are encouraged, but self-nominations are not allowed.

The BJS FY 2026 National Incident-Based Reporting System Estimation Program aims to enhance statistical protocols for crime and arrest data collection in the U.S. This funding opportunity supports the ongoing development of the NIBRS Estimation System, focusing on improving data quality, timeliness, and estimation methodologies. By refining these processes, the program seeks to address public safety challenges and provide reliable national estimates, thereby ensuring effective law enforcement and crime prevention efforts.

The Greenwall Foundation invites proposals for its Bridging Bioethics Research & Policymaking Grants, aimed at integrating bioethics into policy without funding academic research. This initiative addresses ethical dilemmas arising from healthcare advancements, encouraging innovative project ideas at all governmental levels. Grants up to $50,000 will prioritize projects with smaller budgets and shorter timelines. Collaborations with diverse expertise beyond academia, including policymakers, are encouraged to effectively bridge research and policy.

The AOAP Swim Lesson Grant aims to enhance drowning prevention by providing financial support to aquatic facilities for swim lessons and life jackets. With a minimum allocation of $10,000 annually, the program seeks to offer at least 100 free lessons to low-income participants and distribute 500 life jackets each year. It encourages non-profit organizations to apply, ensuring a focus on education and safety in aquatic environments. This grant represents a significant step towards making swimming accessible and safe for all.

Stanislaus Community Foundation provides scholarship opportunities for students in order to help them achieve their educational and career goals. We believe that by investing in our students, we are investing in a brighter future for Stanislaus. 

Jessica Joelle Holt and Emmy Macfarlane Memorial Scholarship

Open to graduating seniors from Pitman, Turlock, and Denair High Schools pursuing a career in teaching.

Award Amount:

• $1,000

The Community Foundation of Chippewa County offers Community Needs Grants to support charitable organizations serving Chippewa County. These grants focus on various sectors, including arts, education, environment, and health. By pooling resources, the foundation aims to foster multigenerational giving, ensuring long-term support for community initiatives. This initiative empowers individuals to contribute to philanthropic efforts without needing significant wealth, reinforcing the spirit of generosity within the county.

The Burroughs Wellcome Fund's Career Awards at the Scientific Interface provide $560,000 over five years to support early-career researchers transitioning from physical and computational sciences to biological sciences. Launched in 1999, these awards aim to enhance academic research careers for U.S. and Canadian citizens, permanent residents, and temporary residents, fostering a diverse and innovative scientific workforce essential for advancing human health.

About Us

We are one of over 900 community foundations in the US. We serve the 7 county Pee Dee region of South Carolina. Our mission is to improve the quality of life in our area of the state.

Who We Are

Eastern Carolina Community Foundation, founded in 2006, is the newest community foundation in South Carolina. We have a permanent endowment to meet the changing needs of the Pee Dee.

• We foster philanthropy.
• We build resources for nonprofits.
• We support our local communities.

FBi Construction Scholarship

FBi Construction created a scholarship fund at ECCF in 2017 to encourage students to enter the construction industry. This interest stems from a strong belief in education and a commitment to improve the quality of life where they do business. This scholarship funding will improve the talent pool which maintains FBi’s commitment to excellence.

About

Paul Newman was born and raised in Ohio by parents who owned a successful sporting goods store. He enlisted in the Navy and completed his military service as a radioman/gunner in the Pacific during World War II. Seeing his father’s business ethic during the Great Depression and experiencing the war fueled his desire to help others in need.

In 1958, Paul made his acting debut on Broadway in “Picnic,” where he also met his future wife, Joanne Woodward. Paul started a successful race car driving career inspired by training for the film Winning. He went on to win second place in the 24 Hours of Le Mans, the world’s oldest endurance race event. After years of acting and being recognized for his achievements on screen and stage, he received many accolades including an Oscar for Best Actor in The Color of Money.

Paul used his fame for good. He was dedicated to civil rights–attending the March on Washington in August 1963–women’s rights, and gay rights. He used his platform to advocate for equal pay for his female co-stars. He was a vocal political advocate committed to ending the nuclear arms race and determined to elect opponents of war and militarism. President Jimmy Carter appointed him to a United Nations General Assembly session on nuclear disarmament.

In 1982, Paul Newman and his friend Hotch founded a food company on a bit of a lark. They turned a profit selling salad dressing that first year, and did something truly radical when they decided to “give it all away” to good causes.

Paul established Newman’s Own Foundation to ensure the continuation of his philanthropic legacy after his passing. 40+ years since its founding, his first of its kind food company and its innovative business model are still going strong.

Garden Grants

Through Whole Foods Market’s Garden Grant program, schools turn outdoor spaces into powerful hands-on learning gardens that connect kids with food, spark their curiosity and support classroom curriculum.

The Diana and Leon Feffer Scholarship Fund, administered by the Community Foundation of Western Massachusetts, provides financial support to residents of Franklin, Hampden, and Hampshire Counties. Eligible students include undergraduates and graduates attending accredited institutions in the U.S. Students can receive up to $3,000, which may affect financial aid. Scholarships can cover tuition and other educational costs, and recipients should confirm tax implications with their colleges or tax advisors.

The Fisher Family Lost Acres Scholarship Fund, administered by the Community Foundation of Western Massachusetts, provides financial assistance to students pursuing agriculture, horticulture, or related majors. Eligible applicants include undergraduate and graduate students planning to enroll in accredited post-secondary institutions in the U.S. Scholarships can reach up to $3,000 and may affect other financial aid. Students are encouraged to check with college financial aid offices for guidance on potential implications.

The Farmers Market Grant Program by Compeer Financial supports farmers by enhancing their marketing and technology capabilities. Grants can be utilized for branding, website creation, and payment technologies, as well as essential equipment like scales and tents. This initiative aims to promote direct consumer engagement and strengthen local food systems, ensuring fresh produce accessibility while fostering economic growth in rural communities. Eligible applicants must be Compeer clients actively participating in verified farmers markets.

This grant aims to enhance safety and health in U.S. mining operations through research in automation, robotics, and intelligent systems. It addresses critical issues like emergency communication and self-escape reliability while supporting the development of field-ready solutions. By leveraging advanced technologies, the initiative seeks to improve miner safety and health, reduce hazardous exposures, and foster community engagement. Applicants must be U.S. academic institutions with accredited mining programs, linking project goals to documented health burdens.

Stanislaus Community Foundation provides scholarship opportunities for students in order to help them achieve their educational and career goals. We believe that by investing in our students, we are investing in a brighter future for Stanislaus. 

Bob Boggeri Farms Fund

Open to students planning to pursue a degree in Ag or Horticulture. Must be a FFA member and demonstrate financial need. Preference given to students from Hughson.

Award Amount:

• $1,000