Best Large Grants for Nonprofit Organizations in Wisconsin

Biogen Corporate Sponsorships provide funding to support congresses, events, and initiatives in exchange for tangible benefits such as marketing opportunities and recognition. Applications are reviewed on a rolling basis, and requests must be submitted 50 days in advance. Biogen considers various disease areas for sponsorship, including Alzheimer’s and Multiple Sclerosis. Approval depends on funding availability, alignment with interests, and event details, ensuring transparency for all potential sponsors.

The Clif Family Foundation Open Call invites 501(c)(3) organizations to apply for grants supporting general operating costs or specific projects. With a focus on regenerative farming, food worker health, climate justice, and food access, the foundation aims to empower grassroots initiatives. Grants range from $5,000 to $50,000, with applications reviewed twice a year. Deadlines are March 1 and August 1, and announcements occur about four months post-deadline.

The Fred C. & Katherine B. Andersen Foundation Grant focuses on enhancing the quality of life in the St. Croix Valley of Minnesota and Wisconsin. It supports 501(c)(3) nonprofit organizations with priorities in healthcare, education, housing, human services, civic initiatives, and environmental education. While capital requests may be considered, the foundation primarily funds operational and programmatic needs. Organizations outside the geographic area may be considered if they align with the foundation's funding priorities.

About the DNR

Preserving and enhancing the natural resources of Wisconsin

In keeping with our mission, the DNR is dedicated to working with Wisconsinites while preserving and enhancing the natural resources of Wisconsin. In partnership with individuals and organizations, DNR staff manage fish, wildlife, forests, parks, air and water resources while promoting a healthy, sustainable environment and a full range of outdoor opportunities.

Aquatic Invasive Species Control – Large or Small-Scale Population Management

(See page 31 of attatched PDF)

When an established population of aquatic invasive species is having adverse effects on a waterbody or wetland, funding is available for control activities. Managing aquatic invasive species can be challenging, but adaptive and integrated pest management can help. Participation in the large- or small-scale control program requires an approved recommendation in an aquatic plant or aquatic invasive species management plan. Eligible projects will implement one or more of the resulting recommendations. Public access required, unless controlling a prohibited species.

DNR cost share: Grants may cover up to 75% of total project costs.

The AIS Population Management Grant includes Small-Scale Population Management Projects and Large-Scale Population Management Projects.

Small-Scale Population Management Projects

Small-Scale Population Management projects will maintain a low abundance of one or more aquatic invasive species populations or further reduce their size. Projects should implement management activities with the goal of continued suppression of the target species where the actions are unlikely to affect the entire lake, stream reach or wetland. Projects should be designed to result in long-term, multi-season suppression of one or more established populations of the target species.

The WDNR Surface Water Grants support organizations in managing surface water through various stages, from planning to implementation. Eligible applicants, including lake associations and conservation organizations, can access funding for education, planning, and management projects aimed at improving water quality and combating invasive species. Key deadlines include May 1 for eligibility inquiries, September 15 for pre-applications, and November 15 for full proposals. These grants reflect the DNR's commitment to sustainable resource management in Wisconsin.

About the DNR

Preserving and enhancing the natural resources of Wisconsin

In keeping with our mission, the DNR is dedicated to working with Wisconsinites while preserving and enhancing the natural resources of Wisconsin. In partnership with individuals and organizations, DNR staff manage fish, wildlife, forests, parks, air and water resources while promoting a healthy, sustainable environment and a full range of outdoor opportunities.

Aquatic Invasive Species Control – Large or Small-Scale Population Management

(See page 31 of attatched PDF)

When an established population of aquatic invasive species is having adverse effects on a waterbody or wetland, funding is available for control activities. Managing aquatic invasive species can be challenging, but adaptive and integrated pest management can help. Participation in the large- or small-scale control program requires an approved recommendation in an aquatic plant or aquatic invasive species management plan. Eligible projects will implement one or more of the resulting recommendations. Public access required, unless controlling a prohibited species.

DNR cost share: Grants may cover up to 75% of total project costs.

The AIS Population Management Grant includes Small-Scale Population Management Projects and Large-Scale Population Management Projects.

Large-Scale Population Management Projects

Large-Scale Population Management projects will result in long-term, multi-season suppression of one or more established populations of aquatic invasive species. Projects are large in scale, affecting a substantial portion of a lake, stream reach, or wetland.

Projects that address multiple populations across a region should employ a strategic approach to managing multiple populations, prioritizing control actions in a way that ensures wise spending of grant funds. For example, a regional wetland control project might focus on populations that threaten high-functioning natural wetlands or focus on small, more easily controlled populations. For Phragmites-focused projects seeking AIS planning and control grant funds, please see the Phragmites Statewide Management Strategy for more specific guidance.

The Conservation Partners Grant Program, funded by the National Fish and Wildlife Foundation, supports private landowners in implementing regenerative agriculture and conservation practices. By awarding competitive grants, the program facilitates technical assistance for developing management plans and best practices, enabling landowners to maximize the ecological benefits of their lands. This initiative is crucial for enhancing fish and wildlife habitats, addressing pressing conservation issues, and promoting sustainable land stewardship across the United States.

The Ordinance Development Projects grant, offered by the Wisconsin Department of Natural Resources, supports the creation of local regulations aimed at benefiting surface water. Eligible activities include ordinance text development, legal work, compliance training, and outreach efforts. Applicants must submit a pre-application by September 15 and a full proposal by November 15, along with a letter of support from the implementing government unit, promoting sustainable management of Wisconsin's natural resources.

The Environmental Justice Thriving Communities Grantmaking Program, led by The Minneapolis Foundation, supports community-based nonprofits in the Great Lakes region. With a focus on underserved communities, grants will total $40 million over three years, aiming to enhance environmental health, education, and resilience. The program prioritizes applications from federally recognized tribes and organizations with limited budgets, fostering inclusive community engagement and sustainable development. Eligible projects include environmental assessments, public health initiatives, and job training.

The Eau Claire Community Foundation (ECCF) offers the ECCF Community Grant focusing on various areas including arts, education, environment, and social services. This grant aims to support programs that enhance community life, provide educational opportunities, and address essential needs for residents. Organizations located in the Eau Claire area or those demonstrating significant impact are encouraged to apply. The foundation prioritizes innovative proposals that foster collaboration and effectively respond to local needs.

The Soil and Water Stewardship Scholarship, sponsored by the Community Foundation of Northern Illinois, provides financial support to students pursuing careers in natural resources. Applicants must reside in specific Illinois counties and plan to enroll in a full-time program related to fields such as ecology, hydrology, and conservation. Academic performance is a key consideration in the selection process. For more details, contact the Winnebago County Soil & Water Conservation District.

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Healthcare Services Expansion Fund

The NAFC Healthcare Services Expansion Fund supports the launch or expansion of clinical programs and new service areas that increase access to care for underserved patients. This funding is designed to help NAFC members introduce new services or grow existing programs that address unmet community health needs and improve access to comprehensive, patient-centered care.

The OECD Conference Sponsorship aims to enhance scientific knowledge and provide essential information to influence policy decisions on sustainable resource use in food, agriculture, forestry, and fisheries. It supports international events that showcase innovative research and developments, inviting applications from scientists in these fields. The event sponsorship encourages collaboration among policymakers, industry, and academia, ensuring that research insights are effectively communicated and utilized in decision-making processes.

The RNRF Planning and Small Grants program provides funding up to $50,000 to support projects that enhance collaboration among community partners in addressing critical environmental issues. Eligible applicants must be 501c3 organizations in the U.S. and demonstrate multidisciplinary cooperation. Projects should align with RNRF's mission and focus areas, including air quality, biodiversity, and renewable energy. The initiative aims to create sustainable and impactful outcomes by bridging research and practical implementation.

The RNRF Implementation/Collaboration Grants support innovative projects that enhance collaboration among stakeholders to address critical challenges in environmental, social, and economic systems. Offering up to $200,000 for initiatives lasting 12 months or more, these grants aim to implement evidence-based practices and facilitate multidisciplinary teamwork. Eligible applicants must be from 501c3 organizations in the U.S., ensuring alignment with RNRF's mission and focus areas, fostering sustainable and impactful outcomes.

RBC Foundation – USA aims to enhance community quality of life by supporting non-profit organizations that promote diversity and positive change. In 2023, it awarded over $2.8 million in grants, prioritizing youth programs for ages 15-29, arts access for diverse populations, and mental well-being initiatives. The foundation encourages sustainable projects that foster economic independence, providing critical support for education, mental health, and cultural enrichment, thereby making a significant impact across various communities.

The Siletz Tribal Charitable Contribution Fund, established by the Confederated Tribes of Siletz Indians, has distributed over $16.3 million in grants since 1999. It supports charitable organizations and local governments in eleven Oregon counties, as well as Native American initiatives across the U.S. The fund prioritizes education, health, public safety, addiction prevention, housing, arts, and environmental preservation, ensuring the Tribe's commitment to community support and cultural heritage.

The Jerome J. and Dorothy H. Holz Family Foundation Grant supports non-profit organizations in Milwaukee and Waukesha Counties. Established in 1996, it prioritizes initiatives focused on education for youth, food and housing security for families, cultural and scientific institutions, and civic support for Hales Corners, Wisconsin. Grants are limited to organizations exempt from federal taxation and do not fund individuals, religious activities, or political organizations.

The AmeriCorps State Competitive Program Grant in Wisconsin empowers organizations to engage AmeriCorps members in addressing critical community needs through service and volunteering. It focuses on enhancing community resilience by funding direct service and capacity-building activities. Priority is given to organizations serving marginalized populations and those focused on youth mental health, veterans' support, environmental stewardship, and reducing community polarization. This initiative fosters civic engagement and strengthens local communities across Wisconsin.

The Big Ten Academic Alliance Smithsonian Fellowship offers unique research opportunities for graduate students from member universities. Eligible candidates can conduct research at the Smithsonian in diverse fields such as anthropology, ecology, and history of science. The fellowship provides a stipend of $45,000 per year, with additional research allowances, and supports both U.S. and international students. This initiative fosters collaboration among leading academic institutions to advance knowledge and innovation.

The ALDI Community Gift Card Program provides financial support ranging from $100 to $1,000 to eligible nonprofits and schools that focus on after-school and out-of-school youth programs, as well as food banks. This initiative aims to empower organizations dedicated to child development and combating food insecurity. By applying, you can gain access to essential resources to further your mission and make a positive impact in your community.

The FY26 Defense Established Program to Stimulate Competitive Research (DEPSCoR) aims to enhance research capabilities in eligible states by increasing the number of university researchers and institutions conducting relevant science and engineering research. Sponsored by the Department of Defense, this program will fund multiyear awards to promote research aligned with national security needs. Applications require a multi-stage submission process, emphasizing early registration and timely proposal submissions.

The Dr. Harry J. Heeb Foundation Grant supports underprivileged and abused children, providing medical attention for related disabilities in the fields of eye, ear, nose, and throat health. It also funds education and training for healthcare providers and nurses. Operating primarily in Florida and Wisconsin, the foundation seeks to improve the lives of those in need through both direct support and research. Grants typically range from $2,500 to $20,000.

Sanofi Philanthropic Donations support non-profit organizations aligned with Health Equity, STEM Education Equity, and Local Communities. Applications are accepted year-round, with a review process of 8 to 16 weeks. The initiative focuses on improving healthcare access, fostering innovation, and addressing social determinants of health. Sanofi emphasizes collaboration and sustainable solutions, advocating for equal opportunities in health and education, and nurturing future talent to tackle medical challenges.

The PNC Foundation aims to enhance the lives of individuals in local communities through partnerships with nonprofit organizations. Their focus includes promoting educational opportunities, particularly for early childhood education, and supporting economic development initiatives. Grants are available for organizations that benefit low- to moderate-income families and enhance community growth. The foundation prioritizes programs that foster sustainability and diversity, ensuring a lasting impact on the communities they serve.

The Froedtert West Bend Hospital Healthy Community Fund aims to enhance community health in Washington County by supporting programs that address priority health needs and social determinants. This fund prioritizes non-profit organizations focused on underserved populations, fostering collaborative efforts that improve health outcomes. Qualifying projects include health education, job training, and community safety initiatives. The fund excludes individual benefit requests and political campaigns, ensuring resources are directed toward community-wide health improvements.

The Pentair Foundation, a corporate philanthropy initiative, focuses on creating sustainable communities through water solutions and STEM education. With over $80 million in contributions since 1998, the foundation emphasizes ecological resilience, water quality improvement, and youth engagement in science and technology. They prioritize grantmaking in specific U.S. states and international regions, fostering vibrant communities and encouraging employee volunteerism. Initiatives are invitation-only, ensuring a targeted approach to impactful philanthropy.