Best Large Grants for Nonprofit Organizations in Wyoming

The TMCity Foundation Grant supports innovative research in neurocognitive healthcare, with funding ranging from $25,000 to $250,000. This grant aims to address critical challenges in mental health by fostering cutting-edge research and transformative technologies. Applicants, preferably 501(c)(3) organizations, can submit letters of inquiry on a rolling basis, with a focus on projects based in Southern California and the Greater Boston area. The Foundation is committed to catalyzing advancements in understanding the brain and delivering effective treatments.

The Community Charter Network Scholarship, provided by the Central Indiana Community Foundation, assists students from Fall Creek Academy or University Heights Preparatory Academy in covering post-secondary educational expenses. This scholarship aims to support those who demonstrate financial need and excel academically. Eligible applicants include former students of these institutions or residents within the IPS district. Awards vary based on available funds and may cover tuition, fees, and other educational costs.

The T32 Training Program for Institutions That Promote Diversity aims to increase the involvement of individuals from underrepresented backgrounds in research related to cardiovascular, pulmonary, hematologic, and sleep disorders. This initiative seeks to support institutions dedicated to serving health disparity populations, ensuring they develop robust training programs. While trainees cannot lead independent clinical trials, they can gain valuable experience under the guidance of mentors, ultimately contributing to improved health outcomes for underserved communities.

The Susie Kubié Symphonic Music Scholarship, established in 2017, provides financial support to talented young musicians from the Albuquerque Youth Symphony Program (AYSP). Each year, up to $4,000 is awarded to new or renewing scholars pursuing a music degree. Applicants are required to submit a personal essay, letters of reference, and a video performance. This scholarship not only aids students in their educational pursuits but also honors Susie Kubié's legacy of dedication to music education.

The Bernice Ash Memorial Award honors the legacy of a retail music visionary by providing a $5,000 grant to mid-career professionals employed by NAMM member companies. This award aims to support emerging leaders in the music industry through professional development opportunities and a one-year mentorship with NAMM Young Professionals. Eligible applicants must have at least five years of experience and agree to use the funds for professional training, enhancing their leadership skills and career growth.

Our Mission and Vision

The Wright Foundation for Sustainability and Innovation exists to foster innovative sustainability initiatives that make a positive impact on our planet. We want to find solutions to the complex challenges facing our world today.

Our vision is to facilitate positive action toward sustainable and innovative solutions in agricultural and environmental sectors that reduce carbon footprints and minimize risk for our communities.

Grant Programs

Wright Foundation for Sustainability and Innovation administers projects directly funded by donors that help reduce carbon footprints through carbon positive practices and emission offsetting. The foundation holds open application periods for projects in the contiguous United States, Puerto Rico and Canada that focus on reducing environmental risk through regenerative agricultural practices, habitat restoration and using natural energy sources to make our communities more sustainable.

Reducing Carbon Footprints

The foundation supports projects that work to reduce carbon footprints through the following initiatives:

• Habitat Reclamation: Restoration of habitats creates spaces for native flora and fauna and microorganisms to survive. Natural landscapes are integral to functioning ecosystems and increasing biodiversity, not to mention creating habitats for pollinator species like bees and butterflies that we so desperately need for agricultural success.

• Regenerative Agriculture: Regenerative agricultural practices have a far-reaching impact on the industry and our lives. We aim to reduce carbon emissions by fostering projects that innovate row crop sustainability and dairy, beef, pork and poultry operations to create practices that are sustainable for years to come.

• Renewable Energy: We care about carbon positive practices that harness renewable resources like solar, wind and biomass for improved efficiencies and overall reduction in use. Organic matter often sourced from agricultural production, garbage and tree pruning can be converted to energy in various ways, recycling it back into the agricultural operation that created it or fueling our communities.

• Soil: Soil sequestering practices have wide-reaching benefits like restoring and building organic matter in the soil and increasing biodiversity. It boosts water infiltration and retention and reduces erosion. Through practices like no till, applying organic matter like manure and biochar, and planting cover crops, we improve soil health as well as take CO2 out of the atmosphere.

• Tree Planting: Planting trees is a simple act that makes a huge impact in our urban, suburban and rural communities. They provide shade, release oxygen and improve air quality, improve soil quality and biodiversity, all of which contributes to offsetting carbon emissions. 

• Water: We want to find ways to protect and restore the integrity of our water resources. We aim to fund projects focused on practices that create efficiencies and reduce the agricultural production impact on water quality and benefit our communities by conserving one of our most important natural resources. 

Tree Canopy Improvement Grant

Funding for projects in tree canopy improvement efforts:

• Increasing tree species diversity
• Planting in urban and suburban areas and green spaces

The Presbyterian Church (U.S.A.) offers financial support through undergraduate scholarships for up to 100 eligible college students each year. Applicants must be members of PC(USA) pursuing their first associates or bachelor's degree at an accredited institution in the U.S. during the 2025-2026 academic year. This initiative aims to assist students in overcoming financial barriers to education while fostering a commitment to service within their communities.

The Dr. Carol J. Chrisman Nursing Scholarship, offered by the Ashland County Community Foundation, supports registered nurses and nursing students from Ashland County pursuing advanced degrees at Ashland University. This scholarship honors Dr. Chrisman's legacy in nursing and community health, encouraging local nurses to further their education. Eligible applicants include full-time nursing students and those employed in public health within the area, with prior recipients allowed to reapply once.

The HEAL initiative aims to translate addiction research into practice to combat the opioid crisis and overdose events. It focuses on identifying barriers to reducing substance use and developing scalable, evidence-based interventions. Emphasizing recovery, prevention, and the integration of mental health, the initiative encourages collaboration among experts in various fields. Although applications are not currently solicited, potential applicants are urged to prepare for future opportunities to apply innovative solutions to enhance addiction treatment and prevention efforts.

Mr. Holland’s Opus Foundation

Who knew that a movie made 30 years ago would become the catalyst for the creation of a namesake non-profit, changing the lives of hundreds of thousands of kids by giving them access to learn and play music in school – keeping music education alive and strong across the country?

Mr. Holland’s Opus Foundation was inspired by the acclaimed motion picture Mr. Holland’s Opus, the story of the profound effect a dedicated music teacher had on generations of students. Michael Kamen, who wrote the score for the film, started the foundation in 1996 as his commitment to the future of music education.

The Foundation donates high-quality musical instruments to deserving, under-funded music programs, and provides an array of support services to school districts. By increasing the school’s inventory of quality, playable instruments, music teachers are given the tools they need to deliver a quality music education to students who want to learn. In collaboration with committed school districts, the Foundation’s investments are strategically placed as part of a K–12 district-wide plan to achieve positive and lasting results. Generations of students will benefit.

Instrument Grants

Mr. Holland’s Opus Foundation donates musical instruments to schools nationwide with a focus on increasing student access to music education programs in low-income communities.

Mr. Holland’s Opus Foundation grants consist of musical instruments and equipment only; no cash grants are provided. Our team handles sourcing, ordering, and delivering the instruments. As part of the application process, we work with the teacher to assess the program’s needs to determine the appropriate instruments and equipment. Note that only student model instruments are provided, and the brand is at the Foundation’s discretion.

The Dementia CAReS Grants aim to enhance the lives of American Indian and Alaska Native communities affected by dementia. By providing funding, training, and support, this initiative focuses on developing actionable strategies within Tribal and Urban Indian settings. Key activities include establishing a network of dementia champions and promoting local best practices. The goal is to empower communities to improve dementia care and outcomes through collaborative efforts and innovative approaches.

The AWWA Scholarship Program, specifically the Veolia Water Technologies & Solutions Vernon D. Lucy III Scholarship, offers a $5000 award to undergraduate students pursuing careers in the water sector. Established by the American Water Works Association, this scholarship honors the mentorship of Vernon D. Lucy III and aims to support the next generation of water industry professionals. Eligible candidates must demonstrate interest in water-related fields, underscoring AWWA's commitment to fostering future leaders.

The Downing-Nix Trust Grant provides funding for organizations engaged in research on muscular dystrophy, maintaining treatment wards in Atlanta hospitals, offering veterinary medicine scholarships, and supporting shelters for small animals. Organizations must qualify as 501(c)(3) charities. Applications are accepted year-round, but submissions by April 15 are required for annual meeting reviews. Priority may be given to hospitals and veterinary schools within Atlanta, GA.

The Hearst Foundation's Health Grant aims to support nonprofits that enhance healthcare access for underserved populations in the U.S. Focused on improving skills and increasing healthcare practitioners, the grant also emphasizes public health and medical research. With a history of funding significant projects, the foundation prioritizes programs that address the complex needs of low-income, rural, and elderly communities. This commitment ensures a sustainable impact on national health outcomes while supporting innovative healthcare delivery systems.

The National Institute on Drug Abuse (NIDA) is launching a specialized entrepreneurship program aimed at life science researchers in the field of substance use disorders (SUD). This initiative will equip researchers with essential skills to transform their innovative ideas into viable products, focusing on aspects such as market evaluation, customer discovery, and intellectual property. The course will be delivered in a hybrid format to engage US-based SUD researchers effectively, fostering collaboration and advancing the field.

The AWWA Scholarships Program, led by the American Water Works Association, aims to support the future of the water industry by investing in students. The Mueller Water Products Continuing Education Scholarship awards $5,000 to an undergraduate student employed by a water utility, emphasizing the importance of practical experience in education. This scholarship not only aids financial needs but also encourages students to pursue careers in water supply, fostering growth in this vital sector.

The Building Hope: Future Forward Schools Prize & Fellowship Program aims to enhance career exploration for middle and high school students. This initiative, launched by Building Hope in partnership with American Student Assistance, recognizes schools that excel in career-connected learning. Awardees receive funding, mentorship, and resources to empower students from diverse backgrounds, ensuring they develop essential skills for future success. With $50,000 available for five schools, this program fosters innovation and prepares students for a changing economy.

Building the Future Workforce Challenge

Awarding $5 million and the opportunity to test bold, tech‑forward solutions that strengthen the advanced manufacturing and industry technician workforce—today and for the future.

About the Challenge

Caterpillar knows preparing the workforce for the future is urgent. Communities, employers, and industry need new ways to close advancing skill gaps. The Building the Future Workforce Challenge invites fresh perspectives from all sectors to rethink training. Up to five teams will be awarded $1 million each for sustainable, tech‑forward solutions that strengthen today’s—and tomorrow’s—advanced manufacturing and industry technician talent pipelines.

What types of solutions are you looking for?

The Building the Future Workforce Challenge aims to identify, test, and scale innovative, sustainable solutions that will address today’s and tomorrow’s advanced manufacturing and industry technician skill gaps. A core requirement of any solution is that it remains relevant amid evolving technology—ensuring that breakthrough innovation and human potential rise together.

Strong proposals for Building the Future Workforce Challenge will meet four criteria outlined in the scoring rubric, and proposed solutions must focus on one or more of the following solution categories for Building the Future Workforce Challenge:

The Dr. Alice M. Hudder- Richard T. Molder Post-Secondary Scholarship Fund, established by Richard Molder, supports Erie County high school seniors pursuing post-secondary education. In 2023, the Erie Community Foundation awarded over $800,000 in scholarships to deserving students. Two awards will be granted: one for students focusing on science, math, or business, and another for those studying art or music, emphasizing financial need and a strong work ethic.

The Southern NM Down Syndrome Families Scholarship Fund Endowment aims to provide financial support for individuals with Down syndrome pursuing post-secondary education or life skills training at accredited institutions. Managed by the Community Foundation of Southern New Mexico, this scholarship embodies the mission of improving quality of life and fostering educational opportunities for diverse communities. It encourages applicants from various backgrounds, including those with disabilities, to achieve their academic and personal goals.

The National Institute on Aging (NIA) is launching a Notice of Funding Opportunity (NOFO) to establish a national consortium focused on improving care for older adults with multiple chronic conditions. This initiative aims to evaluate the effectiveness of integrated primary care interventions through innovative electronic health record (EHR) platforms. By fostering collaborations among researchers and clinicians, the consortium will work to enhance patient outcomes and streamline population health management, paving the way for future advancements in aging care.

The Mexican Scholarship, established by the former Consulate of Mexico in Indianapolis, aims to support students of Mexican descent in pursuing higher education. Funded by the Central Indiana Community Foundation, this scholarship is open to Indiana residents enrolled in accredited colleges or vocational schools. Applicants must demonstrate financial need, maintain a GPA of 3.0 or higher, and preference is given to those of Mexican heritage. Award funds can be utilized for tuition, fees, and essential educational expenses.

Morgan Stanley Alliance for Children’s Mental Health Innovation Awards aim to fund innovative mental healthcare solutions for children in the U.S. This initiative invites U.S.-based 501(c)(3) charities with revenues under $5 million to submit projects. With up to $550,000 in grants, the program focuses on addressing critical mental health issues among youth, fostering equity in access to care, and supporting nonprofits led by young leaders. Awards include up to $100,000 for general and $50,000 for Next Gen projects.

The Avant Garde Award supports innovative research on HIV and substance use disorders, encouraging creative scientists to explore high-risk, high-reward approaches. While applications are not currently being accepted, this initiative by the National Institute on Drug Abuse (NIDA) aims to stimulate collaborations and impactful research. Early-stage investigators are particularly encouraged to consider this opportunity as they develop their proposals for future funding. The program uses the DP1 activity code, fostering transformative advancements in biomedical and behavioral science.

2026 Veterans and Nature Grant

Supporting the health, well-being, and community connection of America's veterans

The National Environmental Education Foundation (NEEF) is pleased to announce grant funding supported by the American Medical Association (AMA) to expand access to nature-based experiences that support the health, well-being, and community connection of America's veterans. AMA has partnered with NEEF to bring an evidence-based health perspective to this effort, underscoring the growing body of research linking time in nature to improved physical and mental health outcomes.

Background

A Pew Research Center survey found that roughly one in four veterans say the transition back to civilian life was at least somewhat difficult. This is especially true for those who return home with stress or trauma. The National Alliance on Mental Illness estimates 11-20% of veterans are believed to experience post-traumatic stress disorder (PTSD) each year.

Nature offers profound restorative benefits for veterans navigating the challenges of post-service life. Time spent outdoors — whether hiking, fishing, camping, or simply sitting among trees — has been shown by numerous studies to reduce symptoms of PTSD, anxiety, and depression, conditions that affect veterans at disproportionately high rates.

Quieting hypervigilance, allowing space for reflection, fostering camaraderie, and reducing isolation are all mental and physical benefits that be found through outdoor recreation. Using America’s public lands to do so provides a powerful and accessible path forward.

Overview

Through the 2026 Veterans and Nature grant, NEEF aims to expand access to nature-based experiences that support veteran health, well-being, and community connection by

• Providing opportunities for outdoor activities on public land that improve the physical and mental health of veterans
• Increasing veterans’ understanding of the physical and mental health benefits of time in nature

The grant will provide up to $10,000 per grantee for projects on federal, state, local, or nonprofit public lands that address physical and mental health in veteran communities.

Examples of project types include outdoor activities, such as hiking, biking, climbing, or fishing; wellness activities, such as forest bathing or meditation; environmental education, such as community science; adaptive programming; and conservation volunteering. Projects are not limited to those listed here.

Oregon Department of Forestry

Vision: Complex and resilient forest ecosystems that endure and adapt.

Mission: To protect and promote resilient forests that benefit all Oregonians.

US Dept. of Transportation Grant - Safe Streets and Roads for All (SS4A) Grant Program

The purpose of this Notice of Funding Opportunity is to solicit applications for Safe Streets and Roads for All (SS4A) grants.

Funds for the fiscal year (FY) 2026 SS4A grant program are to be awarded on a competitive basis to support planning, infrastructural, behavioral, and operational initiatives to prevent death and serious injury on roads and streets involving all roadway users, including pedestrians; bicyclists; public transportation, personal conveyance, and micromobility users; motorists; and commercial vehicle operators.

The SS4A Grant Program includes: 1) Planning and Demonstration Grants; and 2) Implementation Grants.

Implementation Grants

Implementation Grants fund projects and strategies identified in an Action Plan that address roadway safety problems. Implementation Grants may also fund supplemental planning and demonstration activities, as well as project-level planning, design, and development activities for projects and strategies identified in an Action Plan (e.g., project-level 21 National Environmental Policy Act (NEPA) compliance, associated environmental review activities, permits and approvals, construction design, etc.). 

• Expected number of awards: 40 to 70

About Us

Who We Are

The National Federation of the Blind is the oldest and largest nationwide organization of blind Americans. Founded in 1940 and currently headquartered in Baltimore, the NFB consists of affiliates, chapters, and divisions in all fifty states, Washington, DC, and Puerto Rico.

What We Do

Through our network of blind members, we coordinate many programs, services, and resources to defend the rights of blind Americans, provide information and support to blind children and adults, and build a community that creates a future full of opportunities.

What We Believe

We are the only organization that believes in the full capacity of blind people and has the power to transform our dreams into reality. We believe in blind people because we are blind people—from our democratically elected leaders to our diverse nationwide membership.

Scholarship Program

Thanks to our generous partners, there are thirty $10,000 merit-based scholarships currently available. All scholarships are awarded on the basis of academic excellence, community service, and leadership. The finalists are announced every spring. They then attend our national convention in July when the winners of each individual scholarship are selected. 

The American Action Fund for Blind Children and Adults Scholarship

For more than 100 years the American Action Fund for Blind Children and Adults has strived to improve the lives of blind and Deafblind children and adults. Best known for annually producing and gifting Braille Calendars, sponsoring the free Braille books for blind children program, and administering the Braille Readers are Leaders contest, the American Action Fund leads in promoting Braille literacy. The American Action Fund is proud to award this scholarship to a deserving and talented blind person.