Best Large Grants for Nonprofit Organizations in Wyoming

Agricultural producers, non-industrial private forest landowners, Indian Tribes, and water management entities in Wyoming can apply for Natural Resources Conservation Service of Wyoming’s Environmental Quality Incentives Program to fund conservation practices on working lands. Support covers technical and financial assistance to improve soil health, water and air quality, wildlife habitat, and climate resilience on eligible farm, ranch, and forest lands.

Nonprofit 501(c)(3) and 509(a) organizations can seek McGraw Foundation grants of US $2,000 - US $10,000 for education, human services, conservation, health, and cultural programs, including operating, project, or occasional capital support. With a mission to strengthen communities, McGraw Foundation provides U.S. nonprofits, including those in Wyoming, with flexible annual funding across these fields.

Nonprofit 501(c)(3) organizations in Wyoming can seek approximately US $75,000 to support programs or capital projects in areas like youth development, K–12 education, homelessness services, aging, disabilities, and addiction recovery. Grants from Daniels Fund help large, high-performing nonprofits strengthen community impact through program support, general operating funds, or capital campaigns.

Graduate students pursuing research in drinking water quality, environmental science, or public health can access funding through the American Water Works Association’s Dr. Philip C. Singer Scholarship, which awards US $3,000 for impactful water-industry research. Wyoming-based students or those serving Wyoming communities may be eligible if their work addresses current challenges in the water sector.

Wyoming agricultural producers and nonindustrial private forest landowners seeking to enhance conservation on working lands can access funding through USDA Natural Resources Conservation Service of Wyoming. Support includes technical and financial assistance for soil health, water quality, wildlife habitat, and climate-resilient practices across entire operations, with special statewide funding pools for beginning and socially disadvantaged producers.

Nonprofit organizations hosting community events or seeking general operating support in Wyoming and other FNBO service areas can apply for flexible community sponsorship funding. Focused on community impact, First National Bank of Omaha supports efforts in affordable housing, small business development, education and workforce, environmental sustainability, arts and culture, community health, and local cohesion.

Focused on capital projects, First National Bank of Omaha invites Wyoming nonprofit organizations to seek major donations for facilities, construction, renovation, or other large-scale initiatives. Funding supports projects advancing areas like affordable housing, community health, education and workforce development, entrepreneurship, environmental stability, and access to arts and culture in FNBO’s service communities.

Nonprofit 501(c)(3) organizations working on economic advancement, affordable housing, or community arts and culture in Wyoming can seek funding to strengthen local communities. With a mission to create equitable, lasting change, US Bancorp Foundation provides collaborative grants that prioritize organizations in designated U.S. Bank communities and those advancing diversity, equity, and inclusion.

Nonprofit organizations serving women and children with self-sufficiency, humanitarian aid, or child welfare programs in Wyoming can apply for The Father's Table Foundation’s competitive grants, with awards up to US $750,000. Funding may support efforts like homelessness services, education, food security, health care, anti-trafficking, microfinance, and disaster relief projects that expand or deepen impact.

Undergraduate-focused higher education institutions in Wyoming conducting biomedical and health-related research can apply for NIH Academic Research Enhancement Awards, with awards up to US $375,000 for small-scale projects that engage undergraduates. Eligible institutions must grant baccalaureate science degrees and have limited prior NIH funding; nonprofit colleges and universities may be especially suited.

Undergraduate, master’s, and PhD students conducting vertebrate research in regions including Wyoming can apply for the Society for Northwestern Vertebrate Biology’s scholarships, with awards up to US $1,500 for research costs. Funding may cover travel, equipment, supplies, and some educational expenses for degree-seeking students who are or become SNVB members.

Early-career research scientists at low- or middle-income country academic or research institutions conducting clinical trials in areas like cancer, cardiovascular disease, mental health, or other listed conditions may be eligible for the Emerging Global Leader Award. Focused on global health research careers, the National Institutes of Health offers approximately US $140,000 to support intensive mentored development, including applicants from Wyoming-based LMIC institutions.

Nonprofit and community organizations in Wyoming planning AmeriCorps service programs can seek funding up to Up to US $27,000 to address local needs through member-driven projects. Focused on community service and volunteerism, Serve Wyoming invites concept papers outlining proposed activities, community needs addressed, and the number of AmeriCorps members requested as a qualifying first step.

Early-career research scientists at academic or research institutions in eligible low- or middle-income countries, including Wyoming-linked LMIC collaborators, can seek approximately US $140,000 to support mentored health research and protected career development time. US Dept. of Health & Human Services: National Institutes of Health (NIH) supports diverse clinical and public health fields through the Fogarty Emerging Global Leader Award.

Nonprofit 501(c)(3) organizations in Wyoming seeking support for education-focused or youth-serving programs can apply for grants ranging from US $5,000 - US $20,000. John Ben Snow Memorial Trust also considers projects in arts and culture, community initiatives, environmental education, disabilities, and historic preservation, with a preference for new or enhanced programs and short-term, one-time support.

Wyoming nonprofits and government agencies improving wildlife habitat or natural resource values in Wyoming can access funding through Wyoming Wildlife and Natural Resource Trust. Eligible projects include terrestrial and aquatic habitat restoration, open space preservation, mitigation of development impacts, and conflict reduction between wildlife and livestock, with both small and large multi-year projects considered.

Nonprofit and other organizations hosting Wyoming health or science-related congresses, events, or initiatives can seek corporate sponsorship that provides tangible benefits like recognition or marketing opportunities. Grants from Biogen Foundation help support programs focused on neurology, Alzheimer’s, Parkinson’s, multiple sclerosis, ALS, stroke, and related disease areas, with requests reviewed on a rolling basis.

Nonprofit 501(c)(3) organizations in Wyoming working on regenerative agriculture, healthy food access, climate justice, or related environmental initiatives can apply for general operating support from the Clif Family Foundation. Grants range from US $5,000 - US $50,000, with priority for grassroots groups focused in the U.S. and its territories and operating on budgets under $8MM.

Nonprofit and conservation organizations providing technical assistance for regenerative agriculture and habitat conservation in Wyoming can apply for US $250,000 - US $750,000 to support private landowners. National Fish and Wildlife Foundation funding helps staff develop management plans, implement best practices, and enhance soil, water, and wildlife benefits through Farm Bill conservation programs.

The Community Ties Giving Program by Union Pacific Foundation offers local grants aimed at enhancing community well-being through diverse funding priorities. These include safety initiatives, workforce development, community vitality, and environmental sustainability. The program emphasizes supporting organizations that promote diversity, equity, and inclusion, aiming to create impactful projects that resonate with Union Pacific's heritage and mission. Eligible applicants must be nonprofit organizations serving Union Pacific communities and demonstrate a clear need and capacity to deliver effective programming.

The Soil and Water Stewardship Scholarship, sponsored by the Community Foundation of Northern Illinois, provides financial support to students pursuing careers in natural resources. Applicants must reside in specific Illinois counties and plan to enroll in a full-time program related to fields such as ecology, hydrology, and conservation. Academic performance is a key consideration in the selection process. For more details, contact the Winnebago County Soil & Water Conservation District.

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Healthcare Services Expansion Fund

The NAFC Healthcare Services Expansion Fund supports the launch or expansion of clinical programs and new service areas that increase access to care for underserved patients. This funding is designed to help NAFC members introduce new services or grow existing programs that address unmet community health needs and improve access to comprehensive, patient-centered care.

The OECD Conference Sponsorship aims to enhance scientific knowledge and provide essential information to influence policy decisions on sustainable resource use in food, agriculture, forestry, and fisheries. It supports international events that showcase innovative research and developments, inviting applications from scientists in these fields. The event sponsorship encourages collaboration among policymakers, industry, and academia, ensuring that research insights are effectively communicated and utilized in decision-making processes.

The RNRF Planning and Small Grants program provides funding up to $50,000 to support projects that enhance collaboration among community partners in addressing critical environmental issues. Eligible applicants must be 501c3 organizations in the U.S. and demonstrate multidisciplinary cooperation. Projects should align with RNRF's mission and focus areas, including air quality, biodiversity, and renewable energy. The initiative aims to create sustainable and impactful outcomes by bridging research and practical implementation.

The RNRF Implementation/Collaboration Grants support innovative projects that enhance collaboration among stakeholders to address critical challenges in environmental, social, and economic systems. Offering up to $200,000 for initiatives lasting 12 months or more, these grants aim to implement evidence-based practices and facilitate multidisciplinary teamwork. Eligible applicants must be from 501c3 organizations in the U.S., ensuring alignment with RNRF's mission and focus areas, fostering sustainable and impactful outcomes.

RBC Foundation – USA aims to enhance community quality of life by supporting non-profit organizations that promote diversity and positive change. In 2023, it awarded over $2.8 million in grants, prioritizing youth programs for ages 15-29, arts access for diverse populations, and mental well-being initiatives. The foundation encourages sustainable projects that foster economic independence, providing critical support for education, mental health, and cultural enrichment, thereby making a significant impact across various communities.

The Siletz Tribal Charitable Contribution Fund, established by the Confederated Tribes of Siletz Indians, has distributed over $16.3 million in grants since 1999. It supports charitable organizations and local governments in eleven Oregon counties, as well as Native American initiatives across the U.S. The fund prioritizes education, health, public safety, addiction prevention, housing, arts, and environmental preservation, ensuring the Tribe's commitment to community support and cultural heritage.