Best Large Grants for Nonprofit Organizations in Wyoming

What does this program do?

It provides loans and grants to Microenterprise Development Organizations (MDOs) to:

• To help microenterprises startup and growth through a Rural Microloan Revolving Fund.
• Provide training and technical assistance to microloan borrowers and micro entrepreneurs.

Microenterprise Development Organizations must demonstrate experience in managing a Revolving Loan Fund, or:

• Certify that it or its employees have received education and training from a qualified microenterprise development training entity so that the applicant has the capacity to manage such a revolving loan fund.
• Demonstrate that it is actively and successfully participating as an intermediary lender in good standing under the U.S. Small Business Administration (SBA) Microloan Program or other similar loan programs as determined by the Administrator.

 What kind of funding is available?

• Grants are available to provide technical assistance to rural micro-entrepreneurs or microenterprises, up to $205,000 annually.
  • Funding at the requested level is not guaranteed, and at least 15 percent matching funds are required.

• Loans of $50,000 to $500,000 may be used for establishing a Rural Microloan Revolving Fund managed by the Microenterprise Development Organization.
  • Total aggregate debt is capped at $2.5 million.

What are the loan terms?

• Maximum term is 20 years.
• Two-year payment deferral.
• Must establish a loan loss reserve fund.

What terms are required on loans to ultimate recipients?

• Up to $50,000.
• Fixed interest rate.
• Limited to 75 percent of project cost.

How may the funds be used?

Microlenders may make microloans for qualified business activities and expenses including, but not limited to:

• Working capital.
• Debt refinancing.
• Purchasing equipment and supplies.
• Improving real estate.

ConocoPhillips Charitable Investments focus on Water and Biodiversity Stewardship, promoting conservation and restoration of ecosystems. The initiative emphasizes collaboration with communities and organizations to enhance biodiversity, improve water availability, and foster innovative conservation practices. Proposals are evaluated based on their alignment with long-term conservation goals, community engagement, and innovative approaches. Eligible organizations must be recognized as tax-exempt charities or government subdivisions, while ineligible entities include those advancing political causes or engaging in discriminatory practices.

The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.

The Hearst Foundation: Culture Grant aims to support outstanding nonprofits that enhance cultural engagement and artistic talent in the U.S. With a focus on programs that reach young people, the grant prioritizes organizations that create lasting impacts in the arts and sciences. The Foundation allocates 25% of its funding to cultural initiatives, favoring established organizations with a history of significant results. Eligible nonprofits must encourage inclusivity and sustainability in their programs.

Mission Statement

The Wyoming Department of Agriculture is dedicated to the promotion and enhancement of Wyoming's agriculture, natural resources and contribution to Wyoming quality of life.

The Wyoming Department of Agriculture assists the citizens of Wyoming to live safe and healthy lives, promote and preserve our agricultural community, be responsible stewards of our natural resources, and achieve integrity in the marketplace.

Emergency Insect Management Grant

The Emergency Insect Management Program was enacted by the Wyoming Legislature in 2003 to create an account, and program oversight, to assist with emergency management of insect pests and insect vectors.

Insect vectors may include blood-feeding arthropods, mosquitoes, biting flies or other such insects that harbor or transmit pathogens harmful to humans, livestock, agriculture, livestock or natural resources. Insect pests may include grasshoppers, Mormon crickets, or other cyclic or outbreak insect species, in addition to incipient populations of invasive insects including fire ants and Africanized honeybees.

Approved programs shall receive not more than 50% of the total program cost. In special circumstances, programs for the control of outbreak insects may receive up to 75% of the program costs.

This funding is to provide supplemental help to manage emergency outbreaks of insect pests and insect vectors of diseases for the protection of human health and safety, animal health including livestock and wildlife, agriculture and natural resources.

The WaterSMART Enhancing Water Resources Projects program invites eligible entities to secure funding for initiatives that enhance water resource management across various sectors, including conservation, infrastructure improvement, and watershed restoration. Priority is given to projects that collaboratively address community needs and yield significant environmental benefits. This funding opportunity aligns with federal priorities aimed at optimizing resource use and improving grant oversight, as outlined in recent executive orders.

The Western Division Scholarship Program offers up to $5,000 annually to support masters or doctoral students in fisheries science. Awards are based on academic excellence, potential contributions to the fisheries profession, and progress toward a graduate degree. Eligible applicants must be members of the American Fisheries Society and have completed at least one semester in a relevant graduate program within the Western Division's geographic boundaries.

The Wild Sheep Foundation (WSF) offers Grant-In-Aid (GIA) funding to support conservation and management programs for wild sheep populations across North America and Central Asia. Established in 1977, WSF prioritizes collaborative proposals that involve partners and matching funds. The organization has raised over $130 million for wild sheep conservation, emphasizing scientific management and public education about sustainable hunting practices. GIA funding decisions align with WSF's mission and identified priority goals.

Tenant and Housing Justice Grant

Social Justice Fund Northwest (SJF) is pleased to announce the 2026 Tenant & Housing Justice Grant, open to grassroots organizations in Idaho, Montana, Oregon, Washington, and/or Wyoming.

Grant Awards:

• Maximum one-year grant award of $25,000

Focus:

• Tenant and housing justice organizing in Idaho, Montana, Oregon, Washington, and Wyoming

Description

This grant seeks to support organizations working to undo and/or create alternative solutions to exploitative housing systems which were built and are sustained by capitalism, colonialism, classism, racism, xenophobia, and ableism. This grant will fund organizations that meet SJF’s community organizing framework and prioritize communities underrepresented in traditional grantmaking.

Tenant and Housing Justice community organizing work can include, but is not limited to:

• Collective power building among tenants to dismantle and push against the current oppressive housing systems and structures 
  • Examples: rental and utilities assistance, tenants’ rights training, eviction prevention and intervention, etc.
• Local and statewide tenant and housing systems/policy change 
• Tenant leadership development
• Creating collective, cooperative housing structures
• Re-entry organizing by and for folks who were recently incarcerated to provide housing and resources, influence and set policy, etc.
• Disability justice organizing focused on affordable, accessible, and supportive housing for disabled folks and elders
• Survivor-led organizing for people transitioning out of abusive situations

Catholic Extension's Enhancing Pastoral and Social Ministry Grants aim to empower the church to broaden its outreach and foster societal transformation through targeted pastoral and social initiatives. This program supports specific elements of the church's ministerial efforts, including funding for catechetical resources, marriage and family ministries, and social outreach for vulnerable populations. By investing in these areas, Catholic Extension seeks to enhance the church's role in communities, especially following disasters.

The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.

The Karen Colina Wilson Foundation Grant supports programs for children, youth, and women, enhancing their health and well-being through education, art, literature, and music. Established in 2006, the foundation aims to make a positive difference in their lives, particularly in Southern and Western Wayne County, Michigan. Grants typically range from $500 to $10,000, often as matching funds, fostering broader fundraising efforts by local nonprofit organizations.

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

The Laura Jane Musser Fund was established by the estate of Laura Jane Musser of Little Falls, Minnesota to continue the personal philanthropy, which she practiced in her lifetime.

Environmental Initiative Program

The Laura Jane Musser Fund assists public or not-for-profit entities to initiate or implement projects that enhance the ecological integrity of publicly owned open spaces, while encouraging compatible human activities. The Fund’s goal is to promote public use of open space that improves a community’s quality of life and public health, while also ensuring the protection of healthy, viable and sustainable ecosystems by protecting or restoring habitat for a diversity of plant and animal species.

Projects must..

• Focus on protecting/restoring a sustainable ecosystem that is a defined, public open space.
• Promote public access to and use of the defined open space.
• Involve active participation of local community members, with a particular appreciation for volunteer and youth engagement and stakeholder contributions.
• Contain measurable outcomes within the first 12-18 months.
• Include a plan for the long term financial and environmental sustainability of the proposed program.

Projects during any one grant period will be eligible for either:

• implementation grants or 
• planning grants

Environmental Initiative - Implementation Grant Program

Implementation grant applications must demonstrate clear evidence of local community active participation and support.

Projects will be eligible for either planning or implementation funds during any one grant period.

The purpose of FVPSA is to assist States in supporting the establishment, maintenance, and expansion of programs and projects that: Help to prevent incidents of family violence, domestic violence, and dating violence; provide immediate shelter and supportive services and access to community-based programs for victims of family violence, domestic violence, or dating violence and their dependents; provide specialized services including trauma informed services to children exposed to family violence, domestic violence, or dating violence, underserved populations, and victims who are members of racial and ethnic minority populations. The FVPSA reauthorization of 2010 bill was signed into law December 20, 2010. The reauthorization bill enhances upon FVPSA efforts in improvements to the National Domestic Violence Hotline, initiatives in teen dating violence, and services to the nation's territories and program's helping children who witness violence and more.

The Rural Arts Initiative Grant Program, established by the Laura Jane Musser Fund, aims to support nonprofit arts organizations in rural communities. The program encourages access to the arts through scholarships, community engagement, and innovative activities. Priority is given to organizations located in areas with populations under 20,000, ensuring that artistic opportunities are available to both adults and children. Applications are accepted for one year of funding, with potential for up to three consecutive years.

The Environmental Initiative Grant Program by the Laura Jane Musser Fund aims to support public and nonprofit entities in enhancing the ecological integrity of open spaces. It promotes community involvement in planning and implementing projects that improve quality of life and public health while protecting ecosystems. Grants range from $8,000 for planning to $35,000 for implementation, targeting projects in specific states, fostering sustainability, and ensuring active local participation.

The Pinetop Assistance League (PAL) Grant provides crucial financial support to elderly blues musicians, ensuring their well-being during emergencies. This grant, part of the Pinetop Perkins Foundation's mission, offers assistance for medical expenses, home care, and essential living costs. Eligible applicants must be professional artists aged 50 or older with a household income below $35,000. By addressing these needs, PAL plays a vital role in preserving the legacy and care of blues musicians.

Asia-Pacific Network for Global Change Research

The Asia-Pacific region, home to over half the world's population, faces challenges due to its development goals, which strain natural resources, communities, and cultural heritage. These issues are exacerbated by adverse environmental changes. While research has shed light on these problems, it's clear that more challenges lie ahead. The Asia-Pacific Network for Global Change Research (APN) is well-positioned to generate new knowledge and solutions for these evolving global change and sustainability issues by supporting collaborative research and scientific capacity development activities, particularly those aimed at training the next generation of early career professionals.

APN 2025 Call for Proposals: CRRP 

Through the competitive Collaborative Regional Research Programme (CRRP), we promote regional research that has potential to improve our understanding of global change and its implications while contributing to a sound scientific basis for policymaking in areas affected by global change. Under this pillar, APN supports collaborative research that contributes to the evolving science-policy arena, including the UNFCCC Paris Agreement, IPCC, IPBES, post-2015 Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction and the UN Decade of Ocean Science as well as ongoing and new global change and sustainability research programmes.

Activities of interest under the CRRP Programme

APN promotes regional collaborative research that improves understanding of the physical, biological and human dimensions of change in the Earth system and advances actionable science that informs decision-making. APN accepts proposals that engage at least 3 member/approved countries in the region, and prioritise collaboratively designed, actionable research with non-academic stakeholders. Proposals must address one or more of the following activities:

• Collaborative research on global change and sustainability that particularly addresses GAPS, ANALYSIS, SYNTHESIS and ASSESSMENT work.
• Collaborative research that develops PATHWAYS and MECHANISMS to achieve sustainable development, and develop adaptation strategies.
• Collaborative PLACE-BASED INTEGRATIVE RESEARCH, particularly from developing countries.
• Collaborative research that is CO-DESIGNED to contribute to the Paris Agreeemnt, Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction, Post-2020 Global Biodiversity Framework, UN Decade of Ocean Science (2021-2030), and the accumulation of scientific knowledge at IPCC, IPBES, etc.

The Big Bets Fellowship: Economic Opportunity in the United States is a transformative 4-month program designed to empower emerging leaders to tackle economic challenges head-on. With a focus on innovative solutions for job creation, affordable housing, and equitable access to resources, the fellowship equips participants with essential skills and a supportive network. The initiative aims to drive systemic change and promote sustainable economic prosperity, addressing inequalities while fostering resilient communities across the nation.

The National Institutes of Health (NIH) is inviting applications for the Screening, Brief Intervention, and Referral to Treatment or Prevention (SBIRT/P) program. This funding opportunity aims to explore innovative methods for addressing alcohol, tobacco, and other drug use among adults facing health disparities. The initiative seeks research proposals that will implement and evaluate SBIRT/P strategies in collaboration with healthcare and community partners. This approach is crucial for enhancing public health and ensuring effective interventions.

The J.W. Couch Foundation Grant focuses on supporting Wildlife Conservation nonprofit organizations that align with their mission of community betterment and environmental protection. The foundation seeks partnerships with organizations that promote animal wellbeing, early childhood education, teacher support, and outdoor activities. Eligible applicants must be registered 501(c)3 nonprofits or for-profit entities aligned with their charitable programs. This grant emphasizes collaboration and community engagement to create lasting impacts.

The FY26 Bureau of Land Management initiative focuses on enhancing access to cultural and paleontological resources. It aims to foster partnerships, promote education, and engage the public while preserving heritage sites. Key objectives include conducting research, stabilizing at-risk resources, training future professionals, and collaborating with Native American communities. This comprehensive approach aligns with the U.S. Department of the Interior's priorities, ensuring the protection and appreciation of America's rich cultural and natural history.

The Therapeutic Giving program by Johnson & Johnson focuses on funding initiatives that enhance patient access to treatment and advance health equity, particularly in immunology. Eligible nonprofit organizations can apply for support aimed at improving health outcomes through innovative programs. The initiative prioritizes measurable impacts over fundraising activities, emphasizing the importance of addressing healthcare disparities and promoting disease awareness efforts for diseases like rheumatoid arthritis and psoriasis.

The Tribal Wildlife Grants (TWG) program, offered by the US Department of the Interior's Fish and Wildlife Service, provides vital technical and financial assistance to federally recognized Tribes. This funding supports various conservation activities, including habitat protection, species monitoring, and wildlife management, helping to preserve both culturally significant species and ecosystems. TWG grants empower Tribes to implement their conservation priorities effectively and sustainably.

Arbor Rising Grant, established in 2010, is a NYC-based nonprofit providing unrestricted multi-year funding and capacity-building support to nonprofits focused on alleviating poverty. The grant process occurs every three years, with the next round in 2025 being invitation-only. Eligible organizations must demonstrate high potential and effective leadership, typically operating on a modest budget. Arbor Rising prioritizes applicants from the NYC metro area while expanding to cover the lower 48 US states.

About Regions

Regions Financial Corporation is a member of the S&P 500 Index and is one of the nation's largest full-service providers of consumer and commercial banking, wealth management and mortgage products and services. Regions serves customers across the South, Midwest and Texas.

Regions Foundation

Regions Foundation supports community investments that positively impact the communities served by Regions Bank. The Foundation engages in a grantmaking program focused on priorities including economic and community development; education and workforce readiness; and financial wellness. The Foundation is a nonprofit 501(c)(3) corporation funded primarily through contributions from Regions Bank.

Matching Gifts Program

Full-time associates and recent retirees (up to 5 years after retirement) of Regions and its affiliated companies can request a Regions Matching Gift to eligible organizations. The recipient organization must be a 501(c) or 170(c) organization located in the Regions footprint (except for accredited educational institutions, which may be located anywhere in the United States) and has a primary mission that clearly fits one of these categories:

• Economic and community development: Supporting economic prosperity through affordable housing, job creation, small-business development, homebuyer education and retention, neighborhood revitalization and stabilization, food security/hunger relief.
• Education and workforce readiness: Supporting career prosperity through student competency and skill building, college and career readiness, educational access and success, credential building and employment and educator training and resources.
• Financial wellness: Supporting financial prosperity through K-12 and college financial education, adult and workforce financial empowerment.
• Arts and culture: Organizations that promote visual or performing arts, historic or science museums, zoos, botanical gardens, libraries, parks or public radio and television.
• Service members and Veterans: Organizations that have a primary mission of supporting U.S. military service members and veterans.
• Individuals with disabilities: Organizations that have a primary mission of supporting individuals with disabilities.

Regions Matching Gifts for Recent Retirees

Retirees of Regions and its affiliated companies are eligible for the Matching Gift Program for up to 5 years after retirement (the gift date must be within the first 5 years of retirement). Regions will match donations of $25 or more, up to a total of $1,000 per year per retiree.

The Regions Community Affairs team will contact the organization on your behalf to verify the gift and review eligibility.