Best Large Grants for Nonprofit Organizations in Wyoming

The Early Head Start Expansion and Child Care Partnership Grants aim to enhance early childhood services for low-income families across GA, NC, and VA. With approximately $7.7 million in federal funding, this initiative will provide comprehensive support to pregnant women, infants, and toddlers, fostering family stability and community prosperity. The program reflects the Administration for Children and Families' commitment to improving economic and social well-being through accessible, high-quality early education services.

The Holland Scholarship, established in honor of Merle Holland Leis Frenzel, aims to support aspiring music students from Saginaw County. Funded by her friends and former students, this scholarship encourages recipients to pursue their musical dreams while honoring the support of her parents, Norton and Virginia Holland. Eligible applicants must maintain a minimum 3.0 GPA, be seniors at Saginaw County public high schools, and be involved in music programs. Awards typically range from $500 to $4,000.

The Great Lakes Bay Pride Scholarship, offered by the Saginaw Community Foundation, supports Michigan residents dedicated to promoting respect and acceptance across diverse backgrounds. This scholarship is open to high school seniors and college students pursuing undergraduate or Career and Technical Education (CTE) programs, with awards ranging from $500 to $4,000. Eligible applicants must maintain a minimum GPA of 2.5 and demonstrate commitment through volunteer work in the LGBTQ+ community.

Literary Arts Project Grants

As part of its Literary Arts Initiative, South Arts is pleased to announce Literary Arts Project Grants supporting literary arts organizations and small presses that focus on contemporary literary arts.

These grants advance South Arts’ commitment to amplifying the literary traditions and artistic practices of the American South by directly supporting the development, production, and public engagement of high-quality literary projects.

Literary Arts Project Grants support projects in poetry, fiction, creative or literary nonfiction, young readers’ literature, and drama (scriptwriting). Projects must demonstrate artistic excellence, editorial rigor, and meaningful public or community impact.

Award Amount

South Arts will award up to $5,000 per project to eligible literary arts organizations and small presses.

Interface Health Foundation

Interface Health Foundation is a non-profit, 501c3 tax-exempt organization driven by a collective vision of positive change. In healthcare industry policy, understanding the intricate dynamics of funding and its impact on public access, quality, and cost remains paramount. IHF is dedicated to advancing analysis and research into the crossroads of healthcare industry policy, structural frameworks and affordability.

At IHF, our mission is clear: to empower and support student-led research endeavors that shed light on critical healthcare policy and structural issues affecting the public. Through our initiatives, we seek to foster a deeper understanding of the complex dynamics shaping the healthcare landscape.

Interface Health Foundation: Research Grant

Healthcare administrative grant award opportunities are highly competitive and allow candidates to stand out as they enter the job market. Through this IHF grant award, you will get the opportunity to pull together research and content on topics that aren't fully studied or publicized. Depending on the grant topic, some grantees will also have access to a preceptor who is an executive leader in the healthcare field. The preceptor will serve as a valuable resource to the grantee during the development of the research paper and beyond.

An example of a research topic is the impact of legislated acute care nurse staffing levels on the following: nursing professional job satisfaction, the patient experience, and the standard nursing quality indicators as part of nursing Magnet status accreditation.

Building a global community of creative problem solvers, effective collaborators, and empathetic individuals through theatre

Our Mission and Goals

The Educational Theatre Foundation (ETF) is the philanthropic arm of the Educational Theatre Association (EdTA).

ETF advances the field of educational theatre by broadening representation and increasing access for all. ETF’s programs aim to support students, educators and the field at large by realizing three strategic goals:

• Subsidizing new, emerging, and underserved student theatre programs;
• Creating paths for theatre educators to develop new skills; and
• Commissioning research to showcase the value of a theatre education.

Grants for Educators & Theatre Programs

A core piece of the Educational Theatre Foundation’s work is supporting theatre educators and theatre programs directly. We do this through a series of production and educator grants available to both members of EdTA as well as non-members.

For EdTA Members

Production Grants are offered in collaboration with the rights holders for specific plays and musicals or for initiative-based productions that build community.

Production Grants

Show-specific financial assistance for educational theatre programs

The Wilder Estate: The Long Christmas Dinner Festival Grant

In 1931, Thornton Wilder wrote The Long Christmas Dinner, a moving, funny, and ingeniously theatrical one-act play created specifically for student theater groups. In just 40 minutes, a single holiday meal becomes a 90-year journey through four generations of a family, exploring time, tradition, family, and the stories we tell about our lives.

In 2026, the Wilder Estate is launching The Long Christmas Dinner Festival, a national holiday celebration bringing schools, cultural organizations, and audiences together around this remarkable play.

Building a global community of creative problem solvers, effective collaborators, and empathetic individuals through theatre

Our Mission and Goals

The Educational Theatre Foundation (ETF) is the philanthropic arm of the Educational Theatre Association (EdTA).

ETF advances the field of educational theatre by broadening representation and increasing access for all. ETF’s programs aim to support students, educators and the field at large by realizing three strategic goals:

• Subsidizing new, emerging, and underserved student theatre programs;
• Creating paths for theatre educators to develop new skills; and
• Commissioning research to showcase the value of a theatre education.

Grants for Educators & Theatre Programs

A core piece of the Educational Theatre Foundation’s work is supporting theatre educators and theatre programs directly. We do this through a series of production and educator grants available to both members of EdTA as well as non-members.

For EdTA Members

Production Grants are offered in collaboration with the rights holders for specific plays and musicals or for initiative-based productions that build community.

Production Grants

Show-specific financial assistance for educational theatre programs

Music Theatre International: Heart of Rock and Roll "The Power of Love" Grant

Heart of Rock and Roll features a book by Jonathan Abrams and music and lyrics by Huey Lewis and his pop-rock band, Huey Lewis and the News, with new orchestrations of their music by Brian Usifer.

Selected schools will host intergenerational community events or outreach programs of their own design — because just as Huey Lewis’s music has always brought people together, school theatre has the power to do the same.

The Scott R. MacKenzie Foundation offers grants to support innovative genetic research aimed at advancing cures for diseases like cancer, diabetes, lung, and heart diseases. Only U.S.-based tax-exempt organizations with over five years of operation can apply. The Foundation emphasizes collaboration among research entities to enhance genome sequencing and disease detection. By funding these initiatives, they aim to foster awareness and progress in genetic research for future generations.

The Rockefeller Family Fund's Climate Grant focuses on reducing fossil fuel production to combat climate change. It supports initiatives that hold polluters accountable and fosters citizen engagement for climate action. The fund prioritizes programs that seek to limit oil and gas production, enforce climate damages in court, and promote sustainable energy solutions. By addressing the fossil fuel industry's resistance, the grant aims to create meaningful progress towards climate goals and ensure that those responsible for climate disruption contribute to adaptation efforts.

The Cooperative Development Fund Grant supports cooperative development, research, and technical assistance for cooperatives focused on seniors, international development, and affordable housing. Grants, typically ranging from $20,000 to $30,000, are awarded once a year, with a two-stage application process: a concept paper followed by a full proposal for selected applicants. Up to two grants are awarded annually, with decisions announced shortly after the Advisory Board meeting in January.

The RRF Foundation for Aging offers research grants aimed at improving the well-being of older adults and their caregivers. Established in 1950, the foundation has awarded over $239 million to support innovative projects nationwide. Grants are targeted at nonprofit organizations proposing research with immediate implications for adults aged 60 and older, with a focus on practical knowledge and dissemination to impact policy and practice.

Agnes McCarthy Caregiver Foundation

The Agnes McCarthy Caregiver Foundation is a 501(c)(3) not-for-profit charity that provides hope and relief to caregivers who care for a loved one with mental health conditions.

Caregiver Grant

Family caregiving has become a public health issue that receives inadequate recognition in our country. While it can be rewarding to care for our loved ones, it often comes with significant physical, emotional and financial costs to the caregiver. On average, caregivers spend over 25% of their own income to support their loved one and provide 32 hours a week in unpaid care.

AMCF currently offers a $500 financial relief grant to assist family members with unexpected expenses due to their caregiving role. If you are a family caregiver to someone living with a mood or psychiatric condition like depression, anxiety, PTSD, bipolar, schizophrenia, or other mental health/co-occurring conditions, you are not alone, and we welcome you to apply for a caregiver grant today.

Additional Information

• To ensure our limited funds reach families with the greatest need, grants may require documentation confirming a diagnosed serious mental illness (SMI).  

• The $500 grant is limited to one award per household within a 12-month period.

• Applications are generally reviewed by our Board of Directors, with decisions made within 30 days of receipt.

The OJJDP FY 2026 Strategies to Support Children Exposed to Violence program aims to implement effective violence reduction strategies targeting juvenile offenders. This initiative focuses on enhancing community capabilities to assist children affected by violence in various environments, including homes and schools. By strengthening local responses to child victimization, the program seeks to diminish the incidence of violence and alleviate the long-term adverse effects that such exposure can have on children's well-being.

The OVC FY 2026 grant aims to improve outcomes for child and youth victims of human trafficking by integrating policies at state and Tribal levels. This funding opportunity focuses on developing strategic plans to address the challenges faced by minor victims, enhance coordination among systems like child welfare and juvenile justice, and ensure effective identification and prosecution of traffickers. By fostering multidisciplinary approaches, the program seeks to provide comprehensive support and services to these vulnerable populations.

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is set to renew a Notice of Funding Opportunity (NOFO) focused on advancing translational research in maternal and pediatric pharmacology. This initiative aims to enhance precision medicine by developing innovative tools and therapeutics for pregnant and lactating women, infants, and children. The goal is to improve the safety and efficacy of medications while ensuring effective patient-provider communications. Applications are not currently being solicited.

About Wyoming Community FoundationSince 1989, the Wyoming Community Foundation (WYCF) has connected people who care with causes that matter to build a better Wyoming. With over 500 funds and $270 million in assets, we support local nonprofits and make grants in every county. WYCF has granted more than $150 million to charitable causes and works with donors to support the communities and organizations they care about most. Katie Parton Memorial Dance FundThe Katie Parton Memorial Dance Fund grant provides tuition and other financial assistance such as support for costumes, shoes, special equipment, travel stipends, or any other expenses related to dance that might be incurred by someone with Down syndrome or other cognitive or physical disabilities. Organizations qualify if they serve the following counties: Albany, Converse, Natrona, Sweetwater.Priority 1: Any person of any age who has Down syndrome

Priority 2: Any person of any age with a cognitive or physical disability

Priority 3: Any person 18 or under, regardless of ability, needing financial assistance for classesOrganizations do not need to be a 501(c)(3) to receive this grant funding, but the grant funds must be used for the stated grant purpose (covering the tuition, fees, supplies, and travel for individuals).

The Patient-Centered Outcomes Research Institute (PCORI) will announce funding for patient-centered comparative clinical effectiveness research (CER) studies focusing on rare diseases. This initiative encourages collaboration and aims to fill critical research gaps affecting approximately 30 million Americans with rare diseases. Applications can request up to $12 million over five years, including coverage for patient care costs. This funding opportunity is set to open on August 12, 2025, with a focus on addressing pressing patient-centered CER questions.

Pediatric Dermatology Research Alliance Inc 

PHACE syndrome is a neurocutaneous syndrome characterized by large segmental infantile hemangiomas of the face and scalp in association with congenital anomalies that may affect the posterior fossa of the brain, cerebral and cervical arteries, heart, and/or eyes. LUMBAR syndrome is the lower-body counterpart of PHACE, characterized by large segmental infantile hemangiomas of the lumbosacral, buttock or pelvic regions associated with urogenital, spinal, bony, anorectal, and/or renal abnormalities. Those affected experience a wide range of comorbidities with significant psychosocial impact. We invite proposals for clinical research that improves diagnostic approaches, enhances quality of life, and addresses key aspects of disease burden and management.

Applications may be submitted by either a single investigator or multiple investigators at multiple institutions. A total of $40,000 is available and may be awarded as one large-scale project or as multiple smaller awards, depending on the number and quality of applications received. Equal consideration will be given to projects in either of the two award formats with decisions to be based upon merit and available funds.

Focus

Research should focus on PHACE and/or LUMBAR syndromes. Priority will be given to investigators who have not previously served as the senior investigator on an R01 NIH grant or equivalent, and to studies that include multidisciplinary teams with active roles for early-career investigators. Proposals that meaningfully integrate patient perspectives are strongly encouraged.

Important Details

• Up to $40,000 will be funded to support one large-scale project for up to two years, or as multiple awards for smaller-scale projects

Society of Hospital Medicine (SHM)

The Society of Hospital Medicine (SHM) is dedicated to promoting high-value care and achieving optimal outcomes for acutely ill patients. As part of this mission, SHM seeks to address inequities in acute patient care and contribute to a greater dialogue on this important issue. As the home for hospitalists, SHM activates and engages our community to

• Advocate for our specialty, our members, and the diverse patients we serve.
• Promote high-value care and optimal outcomes for acutely ill patients.
• Meet the evolving educational needs of a dynamic specialty.
• Cultivate an inclusive community for hospitalists and support career growth and wellbeing.
• Advance the research and innovation of healthcare delivery, quality, safety, and experience across the care continuum.

Society of Hospital Medicine: Junior Investigator Award

SHM’s Junior Investigator Award was created to recognize junior/early-stage investigators. Junior/early-stage investigators are defined as faculty in the first 7 years of furthest postgraduate training. Applicants must be a hospitalist and a clinician investigator or non-clinicians (i.e., a PhD) researching Hospital Medicine relevant topics. Nominations from mentors and self-nominations are both welcome. Applicants may request feedback about their applications after adjudication of the winner. The winner will present the Junior Investigator Award commendation talk (30 minutes) during SHM Converge.

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Grants & Fellowships

Fellowships

The Mensa Foundation Fellowship program empowers exceptional individuals committed to advancing the application of intelligence in their respective fields.

Details

Our current fellowship, the Gifted Education Fellowship, is designed to empower educators pursuing graduate studies in gifted education or closely related fields, enabling them to make a transformative impact in their classrooms and communities. The fellowship supports both doctoral and non-doctoral students, with awards and renewal terms tailored to each track.

The SMART Scholarship-for-Service Program, managed by the Department of War, aims to enhance the U.S. military's technical workforce by offering competitive scholarships for STEM degrees. With a funding cap of $1.3 billion over ten years, the program prepares scholars for critical roles in national defense, ensuring a pipeline of skilled professionals. Since its inception in 2005, over 8,000 scholarships have been awarded, fostering a strong connection between education and service in defense-related fields.

The Sidney R. Baer, Jr. Foundation offers Clinical Research Grants to support advancements in the treatment and understanding of schizophrenia and bipolar disorder. Focused on organizations with IRS tax-exempt status, these grants aim to enhance mental health services and research. By funding initiatives in cognitive and behavioral sciences, the foundation seeks to improve the lives of those affected by serious mental illness, ensuring they receive the support and resources necessary for a better quality of life.

About

Macchia Family Foundation

Aims to assist those who cannot assist them selves, or who have attempted to better their own lives and/or the lives of their families but have come up just a little short.

• Assisting children and people in need
• Supporting social, educational and philanthropic programs that better peoples lives
• Providing a helping hand to those who need it

The Career Guidance for Trainees Grant, offered by the Burroughs Wellcome Fund, aims to enhance the career development of early career administrators focused on PhD scientists. This grant supports a workshop that equips participants with research evaluation skills to create impactful career-focused interventions. Participants will receive a $15,000 grant to implement their projects, develop networks, and share findings at national meetings, fostering a diverse scientific workforce essential for research innovation and public service.

About the Emporia Community Foundation

Our Mission

To connect caring people with causes that build stronger communities within the Emporia area which includes Chase, Coffey, Greenwood, Lyon, Morris, Osage and Wabaunsee counties.

Team Schnak Strong Fund

The purpose of the Team Schnak Strong Fund is to provide funds to qualified individuals to cover expenses related to the treatment of childhood Type I Diabetes. Grant requests will be considered for children up to the age of 21. Full time students at Emporia State University or Flint Hills Technical College are eligible until the age of 24.

The Stout Foundation Grant supports organizations aligned with the values of its founder, Mr. Stout. Grants are awarded exclusively to entities with 501(c)(3) tax-exempt status and focus on charitable, educational, and scientific purposes. Preference is given to organizations with low overhead costs and those located in areas frequented by Foundation members. The Foundation aims to promote effective use of funds while remaining flexible in its grant-making approach.

Howard Hughes Medical Institute

More than 70 years ago, the Howard Hughes Medical Institute (HHMI) was founded with a mission to advance basic biomedical research and science education. Today, we invest in exceptional scientists at all career stages, catalyzing breakthroughs, new technologies, and the next generation of transformative clinical therapies. Our pathbreaking science takes place at more than 60 host institutions across the US, and at our Janelia Research Campus.

Cech Fellows Program

The Cech Fellows Program is a paid, nine-week summer research experience for rising college juniors and seniors designed to empower the next generation of scientific leaders through mentorship, hands-on research, and community. 

The Cech Fellows Program gives undergraduate students in the life sciences the opportunity to conduct hands-on research with leading scientists at HHMI laboratories across the US, from universities and research institutions to HHMI’s Janelia Research Campus outside of Washington, DC. Students are matched with HHMI scientists conducting fundamental research that advances our understanding of biology and health. 

This immersive program gives students the chance to contribute to real scientific discovery, receive professional mentorship, explore potential careers in biological and biomedical research, and connect with a community of like-minded peers.  

Gain Hands-On Experience in Research & Lab Work

The HHMI Cech Fellows Program is a 9-week, full-time, immersive research experience running from June 14, 2027 to August 12, 2027. Fellows: 

• conduct cutting-edge basic research in an HHMI lab for their own educational benefit  
• participate in professional development workshops   
• engage with a vibrant scientific community  
• build essential skills for future success in a scientific career   

Funding & Logistics 

As a Cech Fellow, students:  

• receive a $15,000 stipend if placed in an HHMI lab at a host institution, intended to cover travel, housing, meals, and incidentals. (Students are responsible for arranging their own housing.) 
• receive a $12,000 stipend if placed at HHMI’s Janelia Research Campus. (Students placed at Janelia have access to free, on-campus housing.)
• participate in an end-of-summer symposium at the Janelia Research Campus in Ashburn, VA, from August 10–12, 2027, at which they present their research and meet other Cech Fellows from across the country. Food, lodging, and travel to and from the symposium are provided by HHMI. 
• are matched with a local contact from their host lab who will provide suggestions for local housing options. Students are expected to travel to arrive at their host institutions by June 14, 2027.