Best Large Grants for Nonprofit Organizations in Alabama

The James B and Lois R Archer Charitable Foundation offers Large Grants for requests exceeding $10,000. Focused on fostering positive change, the foundation supports initiatives in Arts and Culture, Civic Engagement, Education, Health, and Human Services. Eligibility includes 501(c)(3) organizations, while restrictions apply to consecutive grant cycles and non-qualifying purposes such as endowments and fundraising events. Organizations are encouraged to apply for various projects to enhance community well-being.

Our Story

Established over 50 years ago, our founders redefined local philanthropy, fostering connections around a shared sense of place and purpose. As Virginia's largest community foundation, we bring people together to pool resources, co-create solutions and align actions for impactful change in the Richmond region.

Scholarships are offered to students living in the Richmond region and other Virginia locations. Each scholarship was established by a generous individual, family, or organization with a desire to assist high school students, recent high school graduates, and adult learners to continue their education. 

Rappahannock Industrial Academy Alumni Association Scholarship

Rappahannock Industrial Academy Alumni Association Scholarship Fund was established in 2004 by the Academy’s alumni to provide educational scholarships to qualifying African American students residing in one of the following counties: Essex, King and Queen and Middlesex. Students may attend public or private school.

Recipients will be encouraged to use this educational opportunity to enrich the lives of others in their home community. The Rappahannock Industrial Academy opened its doors on January 1, 1902 to provide secondary education for African American residents in the area. The Alumni Association has for many years awarded scholarships to students from Essex, Middlesex, and King and Queen Counties. 

The National Institute on Deafness and Other Communication Disorders (NIDCD) and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) are seeking innovative research applications for non-invasive imaging technologies to study the human olfactory system. This initiative emphasizes the need for advanced multimodal imaging techniques to enhance diagnostic capabilities for olfactory disorders, addressing challenges posed by the system's unique anatomical features. Collaboration among experts is encouraged to foster impactful research developments.

The Lois Lenski Covey Foundation offers the Bookmobile Grant to promote literacy among underserved children. Grants range from $500 to $3,000 specifically for purchasing books for youth from preschool to grade 8. Eligible organizations include 501(c)(3) nonprofits and public libraries that operate lending bookmobiles. The Foundation aims to ensure access to quality literature, fostering a love of reading in disadvantaged communities while addressing their limited book budgets.

The BUILD Grant Program, managed by the USDOT, focuses on enhancing surface transportation infrastructure with substantial local impact. It supports a variety of project sponsors, including state and local governments, in pursuing complex multi-modal initiatives that are often challenging to fund through traditional grants. Established under the American Recovery and Reinvestment Act of 2009, this program reflects a commitment to sustainable and equitable infrastructure development.

Batten Disease Support, Research, and Advocacy (BDSRA) Foundation

BDSRA is dedicated to funding research for treatments and cures, providing family support services, advancing education, raising awareness, and advocating for legislative action. Founded in 1987, by parents seeking to build a network for those diagnosed with Batten disease, BDSRA is now the largest support and research organization dedicated to Batten disease in North America. BDSRA believes that to effectively unravel the mysteries of Batten disease, the worlds of medical science, research, and families must work together toward a common goal: discover treatments and cures while assuring a better quality of life for those living with the disease.

Batten Family Help Grant

The BDSRA Foundation is committed to supporting families of all CLN types in all aspects of their fight against Batten, including the financial challenges they face. BDSRA understands that families in our community caring for people with Batten disease are often faced with financial challenges that further interfere with their well-being.

We offer grants to help cover the costs associated with battling Batten disease, such as emergency travel, loss of employment, hospital bills, and other challenges our families might face.

The AABE National & Regional Scholarship, awarded by the American Association of Blacks in Energy, supports students pursuing careers in the energy sector. Annually, over $350,000 is distributed through multiple scholarships, including six regional awards of $3,000 and one national award of $5,000, renewable for up to four years. Applicants must maintain a GPA of 3.0 and demonstrate commitment to energy-related fields, promoting diversity and equity in education.

Grand Rapids Community Foundation

Connecting people, passion and resources

The Community Foundation is a nonprofit organization that connects people, passion and resources. With our partners, the Community Foundation uses the tools of philanthropy to find solutions to pressing issues. We provide grants to support the work of nonprofits, scholarships to local students and other forms of support to communities working to eliminate barriers to opportunity, prosperity and belonging.

Our Mission is to build and manage our community’s permanent endowment and lead the community to strengthen the lives of its people.

We envision a magnetic and interconnected West Michigan community.

Integrity, Excellence, Inclusion, Sustainability and Bold Aspirations

Give and Receive Openly, Build Trust with Each Other, Create Brave and Safe Space, Embrace Vulnerability, Accountability

Our North Star

For West Michigan to grow and prosper, we must make sure that everyone can apply their talents and creativity to fuel our future. It is only by connecting across perspectives and overcoming inequities that we can build and sustain an inclusive economy and thriving community.

Opportunities for students

Apply for scholarships to support your ambitions

Each year Grand Rapids Community Foundation supports hundreds of students on their college or career training journeys. We are excited to remove barriers to academic success so that students like you can pursue what you're passionate about.

Scholarship Fund Details

Support for West Michigan Students

Attending college or trade school increases opportunity and opens doors to careers. Donor partners who establish a scholarship fund give students a boost on their path to higher education. Students who complete the general scholarship application are considered for these scholarships.

Open to full time students who are residents of Kent County and graduates of a GRPS high school studying healthcare with a minimum 3.0 GPA. Preference for Challenge Scholar students through 2032.

Grand Rapids Community Foundation

Connecting people, passion and resources

The Community Foundation is a nonprofit organization that connects people, passion and resources. With our partners, the Community Foundation uses the tools of philanthropy to find solutions to pressing issues. We provide grants to support the work of nonprofits, scholarships to local students and other forms of support to communities working to eliminate barriers to opportunity, prosperity and belonging.

Our Mission is to build and manage our community’s permanent endowment and lead the community to strengthen the lives of its people.

We envision a magnetic and interconnected West Michigan community.

Integrity, Excellence, Inclusion, Sustainability and Bold Aspirations

Give and Receive Openly, Build Trust with Each Other, Create Brave and Safe Space, Embrace Vulnerability, Accountability

Our North Star

For West Michigan to grow and prosper, we must make sure that everyone can apply their talents and creativity to fuel our future. It is only by connecting across perspectives and overcoming inequities that we can build and sustain an inclusive economy and thriving community.

Opportunities for students

Apply for scholarships to support your ambitions

Each year Grand Rapids Community Foundation supports hundreds of students on their college or career training journeys. We are excited to remove barriers to academic success so that students like you can pursue what you're passionate about.

Scholarship Fund Details

Support for West Michigan Students

Attending college or trade school increases opportunity and opens doors to careers. Donor partners who establish a scholarship fund give students a boost on their path to higher education. Students who complete the general scholarship application are considered for these scholarships.

Open to full time, third-year or higher undergraduate students who are 2+ year residents of Kent County enrolled in a STEM major.

Literary Arts Project Grants

As part of its Literary Arts Initiative, South Arts is pleased to announce Literary Arts Project Grants supporting literary arts organizations and small presses that focus on contemporary literary arts.

These grants advance South Arts’ commitment to amplifying the literary traditions and artistic practices of the American South by directly supporting the development, production, and public engagement of high-quality literary projects.

Literary Arts Project Grants support projects in poetry, fiction, creative or literary nonfiction, young readers’ literature, and drama (scriptwriting). Projects must demonstrate artistic excellence, editorial rigor, and meaningful public or community impact.

Award Amount

South Arts will award up to $5,000 per project to eligible literary arts organizations and small presses.

The Clinical Research Training Scholarship in Parkinson's Disease, funded by the Parkinson's Foundation and the American Brain Foundation, supports young investigators in clinical studies related to Parkinson's disease. Offering $65,000 annually for two years, plus an additional $10,000 for education and research costs, this award aims to foster rigorous clinical research. Eligible applicants must have an MD, PhD, or equivalent degree and be AAN members, focusing on patient-oriented research with human subjects.

The Fund for Wild Nature Grant empowers small non-profit organizations in Canada and the U.S. that prioritize the preservation of native species and ecosystems. With a biocentric approach, this grant supports innovative initiatives combating environmental degradation. Organizations must be tax-exempt and can only submit one proposal annually. Grants do not exceed $3,000, ensuring funding is directed to impactful projects addressing ecological issues often overlooked. Join the Fund in investing in the future of wild nature!

The NIH is inviting applications for interventions aimed at enhancing cancer screening and preventive services in underserved populations. This initiative focuses on addressing barriers to healthcare access and promoting timely follow-up on abnormal findings. Collaborations with community partners are encouraged to foster effective outreach. The program particularly seeks to engage patients, clinicians, and healthcare settings in improving health equity and outcomes in cancer prevention.

The Edwin & Lanier File Ratcliff Memorial Scholarship, administered by the Beckley Area Foundation, supports students from southern West Virginia pursuing higher education. Established to alleviate college expenses, the scholarship targets deserving individuals committed to their academic goals. The Beckley Area Foundation, founded in 1985, connects donors and community partners to enhance local initiatives, focusing on education, health, and community development. This scholarship embodies the foundation's mission to inspire charitable giving and strengthen regional communities.

The OREF/ASES Rockwood Clinical Shoulder Research Grant aims to foster innovative clinical research in shoulder care. By offering seed funding to new investigators, this grant supports promising projects that demonstrate clinical relevance and practical application. Successful completion will position principal investigators to pursue larger NIH or DOD funding opportunities, further advancing shoulder research. This initiative underscores the commitment to nurturing talent and excellence within the field.

The NIDCD Early Career Research (ECR) Award (R21) supports new scientists establishing independent research careers in areas related to hearing, balance, smell, taste, voice, speech, or language. This grant encourages innovative projects such as secondary data analysis, small research initiatives, and technology development, aiming to generate preliminary data for future R01 applications. All applications must be submitted by 5:00 PM local time of the applicant organization.

About Alex’s Lemonade Stand Foundation

Alex's Lemonade Stand Foundation (ALSF) emerged from the front yard lemonade stand of 4- year-old Alexandra “Alex” Scott, who was fighting cancer and wanted to raise money to find cures for all children with cancer. Her spirit and determination inspired others to support her cause, and when she passed away at the age of 8, she had raised $1 million. Since then, the Foundation bearing her name has evolved into a national fundraising movement. Today, ALSF is one of the leading funders of pediatric cancer research in the U.S. and Canada, funding research projects and providing programs to families affected by childhood cancer. ALSF is one of the only childhood cancer research organizations that has been given the NCI peer-reviewed funder designation for rigorous selection of research grants. The mission of ALSF is to change the lives of children with cancer through funding impactful research, raising awareness, supporting families, and empowering everyone to help cure childhood cancer.

Bio-Therapeutic Impact Award

The Bio-Therapeutic Impact Award accelerates the development of clinical trials for promising biologic approaches to treating childhood cancer. These approaches include, but are not limited to, immunotherapy, gene therapy and small molecules. The award, intended for investigators who are initiating clinical trials, totals the maximum of $1.8 million awarded over three years.

About Us

The American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) is an Academy of over 1,100 health professionals dedicated to advancing the health and well-being of all individuals with cerebral palsy and other childhood-onset disabilities. AACPDM is like no other professional society! The “teamwork” mindset of our members solidifies a worldwide network that provides the most effective outcomes for patients. We are pediatricians, neurologists, surgeons, rehabilitators, therapists, nurses, special educators, engineers, and scientists.

AACPDM Mentored Research Grant 

A key part of the AACPDM mission is to foster innovative research as well as its dissemination and implementation. One way the Academy promotes research is through the annual Research Grant Program.

AACPDM Research Grants provide support to bring together investigators from diverse geographical locations to obtain pilot data, statistical consultation and develop a multi-center research study plan.

AACPDM is excited to accept research grant applications that align with the Academy's mission to support a collaborative multidisciplinary community that provides robust scientific education, fosters innovative research, and advocates for equitable access to evidence-based care.

Research grant funding supports high-quality clinical research projects/programs. The award may be used to fund planning for a project or to complete a small research project.

The IEN-WMAN Mini-Grant Program provides crucial financial support to Indigenous communities and grassroots organizations impacted by mining in the U.S. and Canada. With over $200,000 distributed annually in $4,000 grants, the program aims to address mining-related environmental and health issues. Priority is given to proposals that demonstrate a direct impact on affected communities, particularly Indigenous-led initiatives, ensuring that financial assistance is directed where it is most needed.

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 300 funds and approximately $80 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Halfacre Excellence in Music Scholarship

Use the chart below to see which scholarships are the best fit for you! You must complete the Legacy Universal Application to apply.

Scholarship eligibility requires students to attend an accredited 2 or 4 year public or private institution of higher learning. All scholarships are for full-time students, unless otherwise noted. Renewable awards are for 4 years of undergraduate study and cannot be used for post graduate coursework; all awards are paid directly to the school or may be used for book reimbursement.

DREAMS Grant Program

DREAMS For Duchenne

Launched in 2023, Entrada DREAMS is a competitive annual grant program designed to fund efforts within the Duchenne muscular dystrophy community to better identify, understand and reach those who are currently underrepresented and underserved.

DREAMS and Belonging

Entrada is building a company culture where everyone can belong, contribute and grow. In the same way, we are committed to working toward a healthcare system that is equitable and inclusive. Entrada DREAMS is part of our commitment to support Duchenne-focused non-profit organizations in their efforts to address disparities in healthcare and to better serve all people living with Duchenne.

DREAMS and Impact

DREAMS has funded transformative projects that bridge healthcare disparities and strengthen community connections. Keep reading to learn more about past recipients and their projects.

This year, two nonprofit organizations will each receive a $50,000 USD grant to fund projects that advance equity, accessibility and inclusion for individuals with Duchenne. Entrada will award one grant to a U.S.-based nonprofit and another to a nonprofit in the UK or EU.

The NHLBI is launching a Limited Competition Small Grant Program aimed at NHLBI career development award recipients. This program supports researchers transitioning to independence by providing small grants for expanding research objectives or initiating new studies based on their prior work. It encourages applicants to form collaborations and develop impactful projects, although applications are not currently being solicited. This initiative aims to facilitate the generation of essential preliminary data and publications, aiding recipients in their K-to-R transition.

The Byrd Prillerman High School Memorial Scholarship, managed by the Beckley Area Foundation, provides need-based support to Raleigh County students residing in the former Main Gulf area. Preference is given to descendants of past students or teachers of Byrd Prillerman School. This scholarship aims to empower local students in their pursuit of higher education, fostering community growth and educational achievement.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Robert L. & Marjory J. Nelson Memorial Scholarship Endowment Fund

This fund provides scholarships to students pursuing a career in the medical field of study with a preference to those students entering the field of nursing.

Marjory Nelson (1928-1998) received her bachelor of arts degree from Aurora University and her R.N. certification from the Copley Hospital School of Nursing.

She also undertook additional graduate studies at Northern Illinois University and the National College of Education.

She was employed by Copley Memorial Hospital and later served as a nurse for the East Aurora Schools.

This fund was created by Mrs. Nelson’s family and friends to provide recognition of her extraordinary dedication to the field of nursing.

Upon the passing of her husband Robert, the Nelson family added his name to the fund.

Robert Nelson (1924-2015) was a veteran of World War II. He served with the Navy in Europe and the Marines in the Pacific.

He worked in the field of education and was a retired principal in School District 44 in Lombard, Illinois.

Mr. and Mrs. Nelson were survived by two daughters and three grandchildren.

Created in 2004, the fund became an endowment in 2005.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Theodore Silseth Nelson Scholarship Endowment Fund

This fund provides scholarships to students returning to school after a lapse of several years since high school graduation. The awards are given to students pursuing a two or four-year degree in health care, with a preference for both financial need and students seeking a registered nurse certification. Theodore Nelson (1937-2017) was employed as a large commercial account underwriter in the insurance industry. He created this fund out of respect for the competency of those in the healthcare profession and to encourage those who wish to improve themselves by returning to school after being in the workforce. 

The D.K. Shroyer & Alma Davenport Shroyer Memorial Scholarship, managed by the Beckley Area Foundation, aims to support students from Raleigh County, WV, who have completed two semesters of college with a strong academic standing. This need-based scholarship provides opportunities for students pursuing higher education in accredited institutions. The foundation is dedicated to fostering charitable giving to enhance educational success and community growth across Southern West Virginia.

The Early Head Start Expansion and Child Care Partnership Grants aim to enhance early childhood services for low-income families across GA, NC, and VA. With approximately $7.7 million in federal funding, this initiative will provide comprehensive support to pregnant women, infants, and toddlers, fostering family stability and community prosperity. The program reflects the Administration for Children and Families' commitment to improving economic and social well-being through accessible, high-quality early education services.