Best Large Grants for Nonprofit Organizations in Alabama

The ENF Community Investments Program offers Gratitude Grants between $3,000 and $5,000 to Elks Lodges that have met the GER’s per-member-giving goal. These grants empower Lodges to enhance community service and foster local engagement, supporting initiatives that promote health, education, and welfare. The program exemplifies the Elks' commitment to charity and community improvement, showcasing their dedication to building stronger neighborhoods and helping those in need.

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At Women Founders Grant we are catalyzing a no BS movement for women to truly attain Financial Agency.

Women Founders Grant

If you have a dream, we want to support it. We are here to level the playing field and give you the guidance you need to turn that dream into a reality.

Our Grants

• $5,000 Grants on a rolling basis.
• No strings attached.
• This is our biggest differentiator. We know first hand how the folks who have the funds make you jump through unnecessary hoops. No hoops here.
• An Entrepreneur Business Yoda to mentor and coach you.
• GTM support to help you grow and get paying customers.
• On demand resources that guide you through your entrepreneur journey.

• Simply answer two questions on the application page.
• At the heart of our grants, there's no limit to your business dream. From pioneering scientists to artisan bakers, we encourage diverse passions and pursuits.
• So what truly matters is you—the woman or women driving the business forward. We value authenticity over corporate jargon; past winners have simply shared their stories - real passion and vision can’t be faked - so let your’s shine.
• We seek not only business acumen but also the fiery passion that fuels your entrepreneurial journey.

The Mitchell Patrick Mielnik Scholarship, established by the Community Foundation of Middle Tennessee, honors the legacy of Mitchell Mielnik, a passionate hockey player who exemplified integrity. This scholarship supports scholastic hockey players demonstrating excellence in athletics and academics. By fostering Mitchell's spirit of generosity, the foundation aims to empower young athletes to excel in their personal and professional lives, ensuring a positive impact on the community for years to come.

The NRF Foundation Rising Stars Scholarship aims to inspire high school students to explore diverse career paths in the retail industry. By encouraging early participation in the NRF Foundation Student Program, the scholarship allows nominated freshmen and sophomores to gain invaluable insights. Eligible students, nominated by university members, receive a $1,000 travel stipend for the program held in New York City from January 8-11, 2026, fostering their academic and professional growth.

Gabby's Dream Scholarship honors the memory of Gabriella Garven, who tragically passed away but chose to be an organ donor, saving five lives. This scholarship aims to support Muskingum County high school seniors pursuing higher education. Applicants must maintain a GPA of 3.5 or higher and demonstrate involvement in extracurricular activities. By providing financial assistance, this scholarship helps students achieve their dreams, reflecting Gabby's spirit of kindness and generosity, and empowering them to make a positive impact in their communities.

The Kerdyk Family Trust Music Scholarship, administered by the Coral Gables Community Foundation, honors students with a passion for music. Established in memory of Commissioner William H. Kerdyk, Sr., this annual scholarship is awarded to graduating seniors who demonstrate musical interest and academic success. Key eligibility factors include residing in Coral Gables and planning to pursue music studies in college. The scholarship supports students aiming for a career in music, fostering future talent in the arts.

The Lady Suzanna P. Tweed Scholarship, administered by the Coral Gables Community Foundation, honors Lady Tweed's legacy of supporting education and volunteerism. Aimed at students from Coral Gables Senior High, it requires excellence in academics and community involvement. Awards are based on financial need and can be one-year or renewable. Over $2.9 million in scholarships have been granted in the past decade, helping deserving students further their education at various institutions.

The Preventing Violence Affecting Young Lives (PREVAYL 2.0) initiative aims to provide multiyear funding for state and local health departments to implement violence prevention strategies for adolescents and young adults. Key focuses include enhancing data-driven decision-making, building capacity for evidence-based strategies, integrating youth mental health support, fostering multisector collaborations, and prioritizing the prevention of various forms of violence, ensuring comprehensive support for youth development.

The Kubota Hometown Proud Grant is a community initiative that will award ten $50,000 grants in 2025, comprising $25,000 in cash and $25,000 in equipment vouchers. Nonprofit organizations are encouraged to apply for projects that enhance their communities, with applications opening April 3 and closing May 9, 2025. Winners will be announced on September 1, 2025, supporting impactful local initiatives across Kubota's operating districts.

The Pabst Steinmetz Foundation Grant supports innovative projects at the intersection of arts, education, and wellness. It aims to empower organizations that address critical community issues and foster sustainable models for change, particularly in Florida. The foundation encourages collaboration and seeks initiatives that create a ripple effect, enhancing community capacity and promoting impactful solutions. Eligible applicants are 501(c)(3) entities in the U.S. focusing on community betterment through creative approaches.

The Helen Duranleau-Brennan Theater Scholarship, offered by the Quad Cities Community Foundation, supports students pursuing theater studies. Eligible applicants must be graduates from specific Davenport high schools, maintain a 3.0 GPA, and be enrolled in a four-year program or graduate school for theater. This scholarship provides up to $1,000 annually, renewable for up to four years, encouraging students committed to theater-related disciplines and community service.

The Santa Fe Natural Tobacco Company Foundation provides financial support to non-profit organizations that promote American Indian self-sufficiency and culture. Grants are awarded quarterly, and applications must be submitted at least 30 days before meeting dates. Eligible organizations must be 501(c)(3) compliant, focusing on entrepreneurship, education, and cultural preservation. The Foundation, established in 1997, has funded various projects, ensuring that grant funds are utilized effectively for their intended purposes.

The Healthy Lifestyles in Youth program, funded by the Indian Health Service, aims to empower Tribes and Tribal Organizations to deliver essential public health services. This new cohort of NPHR awards supports initiatives that foster healthier lifestyles among youth in Indigenous communities, addressing critical health disparities and promoting well-being through culturally relevant programs and services.

The NLN Edmund J. Y. Pajarillo Health Informatics and Innovation Scholarship offers up to $5,000 annually to support graduate students in health informatics. This scholarship focuses on advancing nursing education through innovative data analysis and technology. Eligible applicants must be enrolled in accredited programs and have completed at least one year of study. Special consideration is given to nurses of color and those from marginalized communities transitioning to full-time teaching roles.

The Don E. & Charlotte Williams Scholarship, administered by the Quad Cities Community Foundation, offers financial support to students pursuing higher education, including community colleges and trade schools. Annually, it provides up to $3,500 for full-time students and $75 per semester hour for part-time students. This need-based scholarship is renewable for up to four years, contingent on maintaining a 2.0 GPA and fulfilling other criteria, prioritizing applicants who are descendants of former employees of the Don E. Williams Company.

The Rhoden Fellowship, supported by ESPN and administered by the United Negro College Fund, is a year-long program designed to empower students from historically Black colleges and universities (HBCUs). Participants will serve as correspondents, creating multimedia content for Andscape, covering major sports events, and producing a bi-weekly podcast. This opportunity not only fosters journalistic skills but also promotes engagement with the HBCU community, paving the way for future leaders in journalism.

The Liz Colantuono & Mark Sanz Endowment Scholarship, offered by the United Negro College Fund, provides need-based financial support to Native American students and adult refugees enrolled or accepted at accredited U.S. four-year institutions. With a focus on those facing financial challenges, this scholarship aims to empower students who demonstrate a commitment to education in STEM, education, accounting, or journalism, thereby fostering future leaders in these fields.

The Hilda M. Hill Memorial Vocational/Technical Scholarship, offered by the Four County Community Foundation, supports seniors and recent graduates from Capac, Almont, and Imlay City pursuing vocational or technical programs. Eligible students must have a minimum GPA of 1.50 and can receive up to two awards, with financial need considered. Award recipients will be celebrated at the Foundation's Scholarship Celebration in May, highlighting the Foundation's commitment to enhancing educational opportunities in the community.

American Brain Foundation

The American Brain Foundation funds research across the spectrum of the brain and nervous system, because it is our best hope for improving treatments, advancing prevention strategies, and discovering cures. Brain diseases, disorders, and injuries are interconnected. When we cure one, we will cure many.

Next Generation Research Grants

The American Brain Foundation’s Next Generation Research Grants (NGRGs) support early career investigators conducting high-quality research aimed at better understanding, treating, and curing brain diseases. These grants are offered in collaboration with disease-focused partner organizations and reflect ABF’s Cure One, Cure Many research philosophy: the belief that breakthroughs in one area of research accelerate progress across many others.

McKnight Clinical Translational Research Scholarship in Cognitive Aging and Age-Related Memory Loss

This award aims to support young investigators in clinical studies relevant to age-related cognitive decline and memory loss. The award also recognizes the importance of rigorous training in clinical research and encourages young investigators to seek opportunities to establish future careers in the area of human cognitive aging.

Please Note: The focus should NOT be on a neurodegenerative dementia (e.g., Alzheimer’s disease); however, proposals that focus on the combined study of cognitive aging and neurodegenerative cognitive changes may be considered.

For the purpose of this scholarship, research is defined as patient-oriented research conducted with human participants, or translational research specifically designed to develop treatments or enhance identification of age-related cognitive decline and memory changes. These may include epidemiologic or behavioral studies, clinical trials, studies of disease mechanisms, the development of new technologies, and health outcomes research. Disease-related studies not directly involving humans are also encouraged if the primary goal is the development of therapies, diagnostic tests, or tools to mitigate age-related cognitive decline and memory loss.

The MI Association of Professional Insurance Agents Scholarship, offered by the Four County Community Foundation, supports seniors and recent graduates in Michigan planning to pursue a major in Risk Management/Insurance. Award recipients will be honored at the Foundation's Scholarship Celebration in May and announced at local high school events. Up to four awards are available, and students must submit an essay for consideration, reinforcing the Foundation's commitment to education and community development.

The Catherine Pierce Scholarship, established by the United Negro College Fund, aims to support students pursuing degrees in the Arts and Art History. This scholarship reflects a commitment to fostering talent and leadership in creative fields. Eligible candidates must be enrolled full-time at an accredited U.S. institution and maintain a minimum GPA of 2.5. Through this initiative, UNCF continues its mission to empower minority students and promote diversity in higher education.

The James J. and Joan A. Gardner Family Foundation focuses on enriching lives and making a positive impact in local communities. They prioritize funding for tax-exempt organizations that enhance education, health care, and support the under-served. The Foundation seeks to partner with those who demonstrate accountability and effective resource management, aligning with their mission for community enrichment and leadership development.

The LUNGevity VA Research Scholar Award supports innovative lung cancer research within the Department of Veterans Affairs, with a focus on early detection and treatment methods relevant to veterans. The maximum award is $100,000, distributed over two years, contingent upon satisfactory progress. Applications are now open for the 2025 cycle, with funding aimed at improving outcomes and developing individualized treatment strategies, including targeted therapies and immunotherapies.

The Human Trafficking Youth Prevention Education (HTYPE) Demonstration Program aims to empower local education agencies (LEAs) by funding initiatives that equip school staff to identify and respond to human trafficking signs. Collaborating with nonprofit partners, LEAs will provide students with essential knowledge on avoiding victimization and recognizing trafficking indicators. This program fosters a safer school environment by establishing reporting procedures and safety plans in consultation with local law enforcement, ultimately enhancing awareness and prevention of human trafficking in educational settings.

The Altrusa Club of Wenatchee Scholarship supports female graduates of Wenatchee Valley College pursuing further education. Funded by the Community Foundation of NCW, this scholarship aims to empower women through financial assistance based on need and academic merit. Eligible recipients must maintain a minimum GPA of 2.0 and demonstrate commitment to their educational goals. This initiative reflects the club's dedication to promoting women's education and ensuring their successful transition to higher learning institutions.

The NIA Postdoctoral Fellowship Award aims to enhance diversity in the translational research workforce for Alzheimer's disease and related dementias (AD/ADRD). This fellowship supports postdoctoral candidates from diverse backgrounds, focusing on the development of translational research skills applicable to AD/ADRD. The program encourages candidates to engage in research experiences within clinical trials under mentorship, fostering a collaborative and interdisciplinary approach to tackling AD/ADRD challenges.

The NIA Predoctoral Fellowship Award aims to enhance diversity in the Alzheimer's disease research workforce. This program supports predoctoral candidates from diverse backgrounds, focusing on translational research skills applicable to Alzheimer's disease and related dementias. It encourages innovative research that can lead to new treatments and diagnostics, fostering a collaborative approach to disease management and care. By developing a diverse research workforce, the program seeks to improve outcomes in treatment, prevention, and early detection of AD/ADRD.