Best Seed Grants for Nonprofits in American Samoa

The Clinical and Translational Science Award (CTSA) Program aims to enhance the translation of scientific research into effective health interventions by establishing a national network of academic medical centers. This program supports integrated research and training environments for clinical and translational science, promoting the development of innovative methods and technologies. The reissuance of the CTSA Notice of Funding Opportunity invites eligible organizations to apply, with peer-reviewed applications prioritized for funding.

The NIAID is dedicated to advancing research on medical countermeasures against chemical and radiation threats, focusing on innovative technologies to diagnose and treat exposure effects. The initiative promotes the development of models, biomarkers, and devices that enhance survival and reduce morbidity during public health emergencies. It supports preclinical efforts to address injuries from designated Chemicals of Concern, emphasizing the need for effective solutions in civilian mass casualty scenarios.

The B-INSPIRE program aims to foster behavioral interventions that enhance interest and preparedness for careers in biomedical research. It invites applications that propose innovative studies addressing motivation and persistence in research-oriented individuals. The initiative also encourages analyses of existing data to improve intervention methodologies. Successful projects should yield findings that support the implementation of diverse strategies across academic levels, ultimately enriching the biomedical research workforce.

The NIH Common Fund Data Ecosystem aims to enhance the reusability of biomedical data through collaboration between Common Fund programs and external data resources. This funding opportunity encourages projects that connect various biomedical data ecosystems, including the HEAL Data Ecosystem and the BRAIN Initiative. By fostering partnerships, the initiative seeks to improve the accessibility and interoperability of valuable datasets, ultimately advancing research efforts. Note that clinical trials are excluded from this funding opportunity.

The Development of Fiscal Year 2027 Commercial Vehicle Safety Plans aims to enhance national safety goals by reducing incidents involving commercial motor vehicles. This initiative, funded by the US Department of Transportation's FMCSA, provides crucial financial support to states and territories. Through the Motor Carrier Safety Assistance Program, the focus is on minimizing crashes, injuries, and fatalities associated with commercial vehicle operations, ensuring safer roads for all.

The Will Rogers Motion Picture Pioneers Assistance Fund offers crucial financial support and counseling for individuals in the theatrical exhibition and distribution sectors facing health-related challenges. This fund assists with medical expenses, housing emergencies, and essential services like vocational rehabilitation and equipment aid. Eligible applicants must have a minimum of three years in exhibition or five years in distribution. The fund aims to provide a safety net for those impacted by illness, injury, or significant life changes.

The AISES SPRK-ing Interest in Computer Science program engages Indigenous K-12 students through fun coding and robotics activities. By utilizing Sphero BOLT and Indi robots, students gain hands-on experience in STEM and computer science, fostering greater interest and competency in these fields. Participating schools receive essential materials and training, promoting a culturally relevant learning experience. Priority is given to middle schools, encouraging greater participation in STEM+CS education among Native students.

The Institute of Education Sciences (IES) offers a grant to support state education agencies in utilizing longitudinal data systems to inform policies and programs for learners with disabilities. This initiative aims to enhance evidence-based decision-making at both state and local levels, ensuring better educational outcomes for at-risk students. The grant encourages collaboration and effective use of data to promote informed policymaking in special education.

The NIH is set to release a funding opportunity for pragmatic and implementation trials aimed at evaluating the effectiveness of interventions in real-world healthcare settings. This initiative encourages collaborations across various health systems to assess the effectiveness and feasibility of interventions. By focusing on commonly encountered conditions in everyday clinical care, the trials aim to provide actionable insights for patients, clinicians, and policymakers. Interested investigators are encouraged to start developing their project proposals.

The ACS-Hach Professional Development Grant provides up to $2,500 to support high school chemistry teachers in the U.S. as they pursue professional development opportunities. This grant aims to enhance teaching and learning in chemistry by funding activities such as conferences, workshops, and educational resources. It is designed to improve educators' skills and boost student achievement, thereby fostering a better learning environment in chemistry classrooms.

The FY26 Peer Reviewed Medical Research Program's Platform Clinical Translation Award facilitates early-phase clinical trials for innovative healthcare technologies, catering to the needs of military Service Members, Veterans, and their Families. The program allows collaborations among multiple Principal Investigators and mandates an external advisory board with patient advocate involvement. Approximately $30M is allocated to fund two applications, each capped at $15M, over a maximum period of four years, with funding contingent on performance milestones.

The Lots of Compassion Grant, supported by KidsGardening and Mrs. Meyer’s Clean Day, aims to transform vacant urban lots into thriving community gardens. By providing $20,000 to each of the 10 selected grantees, the initiative focuses on empowering under-resourced communities, fostering social connections, and enhancing mental health. The grant prioritizes organizations that involve diverse participants and demonstrate significant community impact, ensuring that the gardens not only flourish but also cultivate kindness and compassion.

The Academic Career Excellence (ACE) Award (K32) supports early-stage postdoctoral scholars through rigorous research and career development over three years. Applicants must submit their proposals up to a year before or two years after starting their postdoctoral positions. This award emphasizes innovative research ideas and strategic planning for training and mentorship, aiming to cultivate independent investigators in research fields aligned with the missions of NIH Institutes and Centers.

The Air Force Office of Scientific Research (AFOSR) orchestrates the basic research program for the Air Force Research Laboratory, aligning with technical guidance and Air Force needs. It promotes collaboration among Air Force, universities, and industry, ensuring that research effectively transitions to support military capabilities. AFOSR's focus encompasses significant areas of research organized under two scientific departments, enhancing national defense and peacekeeping operations.

The CTIA Wireless Foundation's Catalyst Grant Program aims to empower social entrepreneurs leveraging 5G technology to tackle critical challenges in American communities. With over $200,000 in unrestricted grants available, the program supports innovative projects that utilize 5G connectivity for social good. As 5G transforms communication and interaction, the Catalyst Grant seeks visionary leaders who can harness this potential to inspire meaningful change and enhance community engagement.

The FY 2027 Service Area Competition (SAC) funding aims to enhance health services in underserved communities across the U.S. by providing grants for comprehensive preventive and primary health care. The initiative supports health centers in delivering essential services, ensuring that vulnerable populations receive the care they need. Service areas for competition are announced periodically, and additional areas may be added if existing centers are unable to continue their services.

The BJS FY 2026 State Justice Statistics Program enhances the capabilities of Statistical Analysis Centers (SACs) to collect and analyze data that supports strategic criminal justice planning. This initiative is vital for federal, state, and local agencies and organizations as they develop policies related to crime and justice. Applications are due by September 29, 2026, at 8:59 PM ET, emphasizing the program's importance in fostering informed decision-making in criminal justice.

The Limited Competition Small Grant Program for ORIP SERCA K01 Recipients provides funding to early-stage veterinary scientists to enhance their research capabilities and transition to independent investigator status. This initiative addresses challenges faced by these researchers, including reliance on funding from senior investigators. Grants support pilot studies, secondary data analysis, and development of research methodologies, aiming to foster independence within a two-year timeframe without funding clinical trials.

The FY 2027 Service Area Competition (SAC) aims to enhance health services in underserved communities across the U.S. by providing grants for comprehensive primary and preventive care. This initiative will support health centers in delivering high-quality services, addressing the needs of populations that face barriers to care. Each funding opportunity will specify service areas available for competition, ensuring effective resource allocation to improve community health outcomes.

The NIH Mentored Patient-Oriented Research Career Development Award (K23) aims to enhance the career development of clinical doctoral degree holders dedicated to patient-oriented research. It supports individuals in their commitment to focus their research efforts on improving patient outcomes. The award has multiple application deadlines, including June 12, 2024, and October 12, 2024, among others, catering to various grant types, including standard, renewal, and AIDS-related applications.

The FY 2027 Service Area Competition (SAC) aims to enhance health services in underserved communities across the U.S. and its territories. This funding opportunity supports comprehensive preventive and primary health care delivery. Each SAC announcement details service areas available for competition, with potential additional areas announced throughout the year. This initiative is crucial for ensuring continuous access to quality health care for vulnerable populations.

The Organizational Change in the Professional Formation of Engineers (ENGINEER:OC) initiative promotes innovative research and activities aimed at transforming engineering education and workforce development. Supported by the National Science Foundation (NSF), it seeks to enhance access to quality engineering programs across diverse institutions. Projects may involve implementing new curricular innovations or adapting existing models to different contexts, ultimately advancing the professional formation of engineers and fostering inclusive educational pathways.

The Professional Formation of Engineers (PFE) initiative aims to enhance the engineering workforce through integrated research and education. It focuses on developing ethical engineers who can adapt to a changing technical landscape. PFE supports diverse training contexts, including formal education, internships, and community experiences, ensuring clear pathways into the profession. This initiative fosters collaboration among engineers, technical workers, and communities, enhancing the skills needed for global competition and technological advancement.

The Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science (RC2 Clinical Trials Optional) aims to foster unique hub capabilities and research platforms to tackle critical gaps in clinical and translational science. Open to eligible organizations involved in the CTSA Program, this funding opportunity is crucial for laying groundwork for future advancements across CTSA Program Hubs. Applications are due by 5:00 PM local time, with Letters of Intent encouraged 30 days prior to the deadline.

The Medical Scientist Training Program (MSTP) aims to cultivate skilled clinician-scientist leaders to meet the nation's biomedical research demands. It supports domestic organizations in developing dual-degree training that integrates clinical and research education, leading to both a clinical degree (e.g., M.D., D.O.) and a Ph.D. Through comprehensive mentoring and career development, MSTP prepares trainees for impactful careers in health-related research, ensuring a robust pipeline of qualified scientists.

The Engineering Biological and Biomedical Systems (EBBS) program, funded by the National Science Foundation (NSF), aims to advance our understanding of biological systems and improve human health through innovative engineering solutions. It supports research that combines mechanistic insights with experimental techniques to develop novel biomedical technologies, enhance biomanufacturing processes, and explore therapeutic applications. Projects focusing on engineering principles for biological responses and rehabilitation are encouraged, while drug design and clinical trials are outside the program's scope.

The HDR Foundation Grant Cycle supports community organizations aligned with HDR's values, focusing on education, healthy communities, and environmental stewardship. This employee-funded initiative emphasizes the importance of employee engagement in grant proposals, requiring a clear scope of work and completion within a year. Eligible applicants include U.S.-based nonprofits, educational institutions, and tribal governments, while grants are not provided for faith-based organizations or individual support.