Best Large Grants for Nonprofit Organizations in Arkansas

The African American Cultural Heritage Action Fund Grants support the preservation of historic sites that reflect African American cultural heritage. Grants ranging from $50,000 to $150,000 assist projects in areas like Capital Projects, Organizational Capacity Building, Project Planning, and Programming. Eligible applicants include public agencies, accredited colleges, and nonprofits. The program emphasizes themes such as activism, innovation, and historically significant sites, aiming to foster a deeper understanding and appreciation of African American history.

The AFAR Grants for Junior Faculty and Glenn Foundation for Medical Research offer up to $160,000 for one- to two-year research projects focusing on the biology of aging. Aimed at early career faculty, these grants support innovative studies not limited to age-related diseases but rather the fundamental mechanisms of aging. Approximately 10 grants will be awarded in 2026, with funding starting July 1. Applicants must be independent investigators within 10 years of their postdoctoral training.

The Edward E. Ford Foundation offers Traditional Grants to independent schools in the U.S. for projects that enhance educational opportunities. With over $118 million granted since its inception, the Foundation emphasizes the importance of matching funds, requiring a dollar-for-dollar commitment from schools. Eligible institutions must serve grades 9-12, be NAIS members, and have a qualified Head of School. Applications are considered during the June and November Agendas, supporting diverse educational initiatives.

The EEFF Educational Leadership Grant, initiated in 2008 by the Edward E. Ford Foundation, supports innovative proposals from independent schools that aim to impact educational practices nationally. Schools can apply without prior invitations, and grants are awarded based on proposal quality. Eligibility includes serving grades 9-12, having a diverse mission, and a head of school in their third year. The program encourages original thinking and partnerships beyond the school community, aiming for significant, replicable change.

The BJA FY 2026 John R. Justice Formula Grant Program offers loan repayment assistance to local and state prosecutors and public defenders who commit to three years of service. Administered by state agencies, this program aims to alleviate the financial burden on legal professionals dedicated to public service. Applications are due by November 10, 2026, providing a crucial opportunity for eligible beneficiaries to secure support for their educational loans.

Napa Valley Community Foundation

We work side-by-side with local donors and nonprofits to tackle the most important challenges our Valley faces.

Our Board and staff are completely dedicated to the people and causes of Napa Valley and represent communities from American Canyon to Calistoga. They share skills, perspectives and the collaborative spirit that define our Napa Valley diversity.

Daisy Cavalli Scholarship Fund

The Daisy Cavalli Scholarship Fund benefits graduating seniors who attend a Napa Valley Unified School District high school and will be enrolling in a trade school, community college, or four-year college/university. Recipients will receive funding for each year that they are enrolled as a full-time student.

Consideration is given to first generation college students (i.e. neither parent has obtained a Bachelor’s Degree).

Napa Valley Community Foundation

We work side-by-side with local donors and nonprofits to tackle the most important challenges our Valley faces.

Our Board and staff are completely dedicated to the people and causes of Napa Valley and represent communities from American Canyon to Calistoga. They share skills, perspectives and the collaborative spirit that define our Napa Valley diversity.

Edward W. Solomon Scholarship

The Edward W. Solomon Scholarship is offered by CalRTA Napa Valley and administered by Napa Valley Community Foundation. It is awarded in memory of Dr. Edward W. Solomon. The Solomon Scholarship is given to support current Napa County teachers/educators who are continuing their education. Previous recipients of the scholarship are eligible to reapply.

In addition, applicants must demonstrate the potential for academic success by having been accepted in an upcoming college or university upper division or graduate level education program or course. Community college courses are acceptable only for current teachers who want/need to supplement their credential authorizations, and if the community college course is acceptable to the CTC Credentialing Office.

Napa Valley Community Foundation

We work side-by-side with local donors and nonprofits to tackle the most important challenges our Valley faces.

Our Board and staff are completely dedicated to the people and causes of Napa Valley and represent communities from American Canyon to Calistoga. They share skills, perspectives and the collaborative spirit that define our Napa Valley diversity.

George & Gwendolyn Goodin Endowment Fund

The George and Gwendolyn Goodin Endowment Fund provides one-year college and university scholarships to Napa County residents who are military veterans, or Napa County residents who are dependents of military veterans who were wounded or died while in active service. The number of scholarships awarded and the amount of each scholarship will be determined by the Fund’s Scholarship Selection Committee.

Clinical Research Training Scholarship in Autoimmune Neurology

This award recognizes the vital importance of rigorous clinical and translational research and aims to inspire and support early-career investigators pursuing clinical studies in autoimmune neurology — specifically immune-mediated diseases of the nervous system other than multiple sclerosis.

The scope of this award encompasses research on autoimmune neurologic disorders, including neural antibody-associated diseases of the nervous system, autoimmune encephalitis, immune-mediated epilepsy, autoimmune movement disorders, inflammatory myelopathies, NMOSD, MOGAD, paraneoplastic neurological syndromes, neurological complications of cancer immunotherapies, and inborn errors of immunity/autoinflammatory syndromes affecting the nervous system.

This award will consist of a commitment of $65,000 per year for two years, plus a $10,000 per year stipend to support education and research-related costs for a total of $150,000. Supplementation of the award with other grants is permissible, but to be eligible to apply for this award, the other grant source(s) cannot exceed $75,000 annually.

The Hillman Emergent Innovation Grant supports innovative, nursing-driven solutions aimed at enhancing health equity for marginalized groups, including BIPOC, LGBTQ+ individuals, and others facing healthcare barriers. This program encourages transformative proposals that challenge traditional care strategies, demonstrate best-in-class potential, and showcase scalability. Eligible applicants include nonprofit organizations, government entities, and faith-based organizations that adhere to inclusive practices. Priority is given to proposals fostering community engagement and measurable outcomes.

Stark Community Foundation

Since 1963, Stark Community Foundation has been helping individuals, families, businesses and nonprofits like you support the causes you care about.

In addition to personalized donor services, we manage a competitive grantmaking program and award grants to address local needs. Today, the Foundation stewards over 1,000 charitable funds totaling $485 million in assets and has granted more than $300 million to nonprofits in our community and beyond.

Scholarships

Stark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.

The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties.

The Jack O. Weimer, Jr. Scholarship Fund

The Jack O. Weimer, Jr. Scholarship Fund assists current or former residents of Stark County enrolled or accepted in a graduate program in a business-related field. Preference will be given to individuals demonstrating financial need. Personal interview may be required.

This scholarship is renewable.

The AAD Young Investigator Awards recognize promising dermatology researchers in the U.S. and Canada, offering a $6,000 prize and plaque for outstanding research in either basic/translational or clinical tracks. Eligible applicants must have a DO, MD, or PhD, and their research should be completed and submitted for publication. The application window is open from June 1 to September 1, encouraging diversity within research topics and applicants.

Stark Community Foundation

Since 1963, Stark Community Foundation has been helping individuals, families, businesses and nonprofits like you support the causes you care about.

In addition to personalized donor services, we manage a competitive grantmaking program and award grants to address local needs. Today, the Foundation stewards over 1,000 charitable funds totaling $485 million in assets and has granted more than $300 million to nonprofits in our community and beyond.

Scholarships

Stark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.

The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties.

The John Onaitis Memorial Scholarship Fund

The John Onaitis Memorial Scholarship Fund awards scholarships to Stark County vocational student graduates pursuing post-secondary education from a college, university, trade or apprenticeship program.

This scholarship is renewable.

The Allen Foundation Grant supports initiatives that enhance human nutrition through research, education, and training. It prioritizes projects that develop nutritional programs, including mandatory nutrition courses in medical schools and sustainable food systems. Eligible applicants must be U.S.-based non-profits or governmental entities with a focus on nutrition education and research. The foundation encourages proposals that include matching funds and has specific criteria for academic research and budgetary self-sufficiency.

The SPARK-EHS initiative aims to broaden the reach of NIEHS training by launching innovative environmental health programs for predoctoral trainees at institutions without recent NIEHS T32 funding. This initiative focuses on research regarding the impact of the environment on biological systems and seeks to translate findings into practical health solutions. Eligible institutions will receive support for developing and implementing these targeted training programs, fostering advancements in environmental health research.

Stark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.

The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties. In 2025, more than $1,000,000 was awarded to local students to help them achieve their educational dreams.

The Clark H. and Louise A. Criss Charitable Fund

The Clark H. and Louise A. Criss Charitable Fund was established to assist Stark County, OH high school graduates attending a two or four year university, college, or technical school. 

Amount:

• Varies. Minimum $500.

Renewable:

• Yes

Hemophilia Fellowship

This competitive grant program seeks to support an institution-based fellowship that emphasizes shared decision making (SDM), patient education, and multidisciplinary team-based care. The intent is to strengthen the hemophilia care through equitable education, and patient-centered shared decision making in a rapidly evolving treatment landscape.

Geographic Scope

• United States 

Funding Range and Project Length

• Grant funding is available to support a one year fellowship up to $100.000 USD. 

Investigating the Benefit of Early Treatment with Ritlecitinib in Alopecia Areata: A Real-World Evidence Approach

Alopecia Areata (AA) is a chronic, immune-mediated condition causing nonscarring hair loss that affects about 2% of the global population and can lead to substantial psychosocial burden if disease is severe and untreated. The treatment landscape has recently evolved with the approval of ritlecitinib, a systemic therapy for severe AA in adults and adolescents aged 12 years and older, based on efficacy demonstrated in the ALLEGRO phase 2b/3 program.

Despite this advance, important questions remain regarding the optimal timing of therapy initiation. Emerging post-hoc analyses from the ALLEGRO program indicate that patients with shorter disease duration and lower baseline severity achieve higher response rates, suggesting that earlier intervention with ritlecitinib may lead to improved outcomes.

Geographic Scope

United States 

Funding Range and Project Length

Individual projects requesting up to $100,000 USD will be considered.

Maximum project length is 24 months.

The Donaghue Foundation's Another Look Grant focuses on enhancing health and well-being for older adults in long-term care facilities. It prioritizes research that utilizes existing datasets and includes stakeholders to inform project development. High-priority topics include improving palliative care, workforce innovations, and addressing disparities in care quality. This program is open to PhD investigators from tax-exempt institutions in the U.S., aiming to foster impactful health-related research that enhances care quality for seniors.

Summer Medical Internship Program (SMIP)

Fosters an interest in research by funding a summer research project conducted by a medical student.

The SIR Foundation Summer Medical Internship Program introduces medical students to interventional radiology research and medical device development. The goal of this program is to foster an interest in research by funding a summer research project conducted by a medical student.

Students applying for the program must show strong potential for a career in IR with proven academic success. Selected students will have an opportunity to intern with an interventional radiologist research mentor or corporate research and development mentor for 8 weeks during the summer.

SIR Foundation will provide a $6,000 stipend to help ease the financial burdens throughout their internship experience.

• Budget: Up to $6,000
• Grant Length: Eight weeks

The Alpha Omega Alpha/Pharos Poetry Award

To encourage students to write effective poetry. Winning poems are published in The Pharos.

The Award

Up to 5 poems will receive a $1,500 award. The winning entries will be published in The Pharos.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders 

There remains a scientific gap in understanding of the role of anti-TFP Imediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Geographic Scope

Brazil, China, Europe, Israel, Japan, Saudi Arabia, South Korea, Turkey, USA

Funding Range and Project Length

Individual projects requesting up to $50,000 USD will be considered.

Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.

Maximum project length is 1 year.

The DAR Historic Preservation Grants, offered by the National Society Daughters of the American Revolution, provide $250,000 annually to support projects that preserve historic resources and sites. Eligible applicants must secure additional funding and adhere to preservation guidelines. Projects must recognize DAR's contribution publicly and can include restoration, digitization, and conservation efforts. Preference is given to projects reflecting Colonial to Federal periods, fostering a deep appreciation for American history.

The North Central Soybean Research Grant Program (NCSRP) aims to enhance soybean production through collaborative research and outreach. By investing in innovative projects, it addresses key challenges in soybean yield, profitability, and environmental sustainability. The program encourages proposals that focus on genetic improvement, pest control, and production practices tailored for the North Central region. Funded projects are expected to deliver practical benefits to soybean farmers while fostering communication and collaboration among stakeholders in the industry.

The WASPC Traffic Safety Grants provide funding for law enforcement agencies to enhance traffic safety initiatives. Agencies can apply for specific traffic safety supplies, including lidar and radars, with maximum award amounts clearly outlined. Eligible applicants must demonstrate participation in statewide traffic initiatives, while ineligible requests include those for replacing existing equipment. This funding aims to prioritize traffic safety enforcement and improve community safety through targeted efforts.

The AR Forest Legacy Program aims to protect threatened forest areas from conversion to non-forest uses through the purchase of conservation easements or fee simple titles. This federal program, funded up to 75%, is available to states with significant forest land, including Arkansas since 2004. The program prioritizes projects that maintain environmental integrity and economic viability, supporting sustainable forest management while enhancing biodiversity and recreational opportunities.

The NIAID aims to enhance infectious disease research by supporting human microphysiologic systems (MPS) development. These in vitro platforms mimic human tissue functions, promoting drug and biological product development while reducing animal use. This initiative aligns with NIH’s commitment to innovative research practices and regulatory acceptance. By focusing on MPS in infectious disease contexts, NIAID seeks to streamline therapeutic advancements and establish robust human tissue models, addressing critical challenges in understanding and treating infections.