Best Large Grants for Nonprofit Organizations in Connecticut

The SHAPE America Hall of Fame Award recognizes individuals who have made significant contributions to health and physical education, ensuring these fields remain central to educational programs. This prestigious award honors dedicated professionals, including educators and leaders, who have demonstrated exemplary commitment and leadership in promoting physical activity, health education, and related disciplines. Through their efforts, they enhance the quality of education and the well-being of students across the nation.

Mesothelioma Applied Research Foundation Inc

The Mesothelioma Applied Research Foundation is the only nonprofit charity organization dedicated to ending mesothelioma, and the suffering caused by this cancer, by:

• funding research to improve treatment options;
• providing treatment support and education for patients and their families;
• and advocating for federal funding of research.

The mission of the Mesothelioma Applied Research Foundation spans across four distinct areas: through research, education, support, and advocacy the Foundation seeks to eradicate the vicious effects of mesothelioma. Led by the Board of Directors, our team works collaboratively to develop and administer our programs, and to fundraise to pay for those programs (the Foundation is funded by private individual and corporate contributions only — it does not receive any government funding).

Patient Travel Grant Program

A mesothelioma diagnosis and treatment often require the patient and their family to incur numerous expenses as part of their treatment. Travel to treatment, alone, can cause a significant financial burden on the patient, which might even cause the patient to not seek treatment away from home, even it’s their best option. To ensure that all patients have the ability to seek specialized help and treatments, the Mesothelioma Applied Research Foundation administers its Travel Grant Program.

The Meso Foundation’s Patient Travel Grant Program, founded by Mary and Bob Cosentino, provides travel grants to patients and one caregiver traveling for an initial consult and/or for clinical trial treatments.

• The type of eligible travel must fall into at least one of these two categories:
  • One trip for one initial consultation with a mesothelioma specialist.
  • Multiple trips to participate in an interventional clinical trial (found on clinicaltrials.gov).

The Marian and Wayne Sinsel Scholarship, established by Marian Sinsel to honor her late husband Wayne, provides financial support to hearing impaired residents of Appalachian Ohio or Fairfield County. This scholarship aims to assist candidates who are 22 years or younger and plan to pursue education at a post-secondary institution in the U.S. with a minimum award of $1,000, ensuring it does not displace existing state or federal funding.

The Great Lakes Bay Pride Scholarship, offered by the Saginaw Community Foundation, supports Michigan residents dedicated to promoting respect and acceptance across diverse backgrounds. This scholarship is open to high school seniors and college students pursuing undergraduate or Career and Technical Education (CTE) programs, with awards ranging from $500 to $4,000. Eligible applicants must maintain a minimum GPA of 2.5 and demonstrate commitment through volunteer work in the LGBTQ+ community.

The Joan M. Wismer Foundation, established in 2001, honors the legacy of Joan Marilynn Wismer, who was dedicated to charitable work and community service. The foundation focuses on improving lives through education, youth development, safety, humanitarian services, and medical research. It primarily supports IRS-recognized 501(c)(3) organizations, schools, and churches, while emphasizing the importance of sustainable funding and effective financial management in its grant-making process.

The Jane Tschappat Nursing Advancement Scholarship, established by The Columbus Foundation, aims to support nurses pursuing advanced education in Ohio. Initiated in 1943, it honors Jane Tschappat, a dedicated nurse and public health leader. Eligible candidates must be enrolled in accredited programs, hold a valid RN license, and demonstrate financial need. The scholarship offers a minimum award of $1,000, empowering nurses to navigate the evolving healthcare landscape and enhance their professional qualifications.

The TTF Advertising for the Environment Grant, established by the Temper of The Times Foundation in 1997, aims to enhance awareness of wildland conservation through marketing initiatives. This grant is exclusively available to 501(c)(3) nonprofit organizations and funds various advertising campaigns to protect native ecosystems. Priority is given to projects that demonstrate measurable impacts on conservation, rather than those focused solely on education.

The Huether/Gillan Scholarship, established by the Niskayuna Community Foundation, supports community-minded students from Niskayuna or its school district. This need-based scholarship aims to assist those pursuing higher education while emphasizing academic achievement and community service. Mr. Huether initiated this scholarship in honor of his parents, promoting values of dignity, diversity, impact, inclusion, innovation, and integrity. Interested applicants should contact Mr. Vince Bianchi for further details.

The Holland Scholarship, established in honor of Merle Holland Leis Frenzel, aims to support aspiring music students from Saginaw County. Funded by her friends and former students, this scholarship encourages recipients to pursue their musical dreams while honoring the support of her parents, Norton and Virginia Holland. Eligible applicants must maintain a minimum 3.0 GPA, be seniors at Saginaw County public high schools, and be involved in music programs. Awards typically range from $500 to $4,000.

The NIHCM Foundation's Policy Research Award honors outstanding research published in peer-reviewed journals that significantly contributes to improving the affordability, accessibility, and quality of healthcare in the U.S. The winner will receive a $20,000 prize. Eligible entries must address healthcare affordability and be published in 2025, with a maximum of three submissions per author. This award aims to recognize innovative insights that can inform policymakers and stakeholders in the healthcare sector.

The Patient-Centered Outcomes Research Institute (PCORI) will announce funding for patient-centered comparative clinical effectiveness research (CER) studies focusing on rare diseases. This initiative encourages collaboration and aims to fill critical research gaps affecting approximately 30 million Americans with rare diseases. Applications can request up to $12 million over five years, including coverage for patient care costs. This funding opportunity is set to open on August 12, 2025, with a focus on addressing pressing patient-centered CER questions.

The Manning Family Foundation offers Health and Life Sciences Research Grants to support innovative research aimed at finding effective treatments and cures for diseases like diabetes and macular degeneration. Since 2003, they have funded 501(c)(3) nonprofits that contribute to these fields, emphasizing entrepreneurialism and impactful research. Applications are accepted on a rolling basis, with awards given three times a year, fostering advancements in health and community well-being.

The Brett Candela Lacrosse Scholarship, established by the family of Brett Candela, honors his passion for lacrosse and supports central Ohio players pursuing higher education. A standout athlete from Columbus, Brett was recognized for his leadership and competitiveness in lacrosse and basketball. This scholarship aims to invest in student-athletes who embody his values of dedication, teamwork, and perseverance, ensuring that the next generation of lacrosse players can achieve their educational goals while upholding Brett's legacy.

The Bloomberg Green Docs Contest invites filmmakers to create impactful short documentaries addressing climate change. Competing for a grand prize of $25,000, participants are encouraged to showcase urgent narratives about our climate future. The films should be under 10 minutes, including credits, and highlight both restoration efforts and the challenges posed by climate extremes. Winners will be revealed at the Bloomberg Green Docs Film Festival, making this a pivotal opportunity for storytellers passionate about environmental issues.

The Undergraduate Development Program Student Travel Award offers undergraduate science majors a unique opportunity to attend the Society of Toxicology Annual Meeting from March 21–23, 2026. The program aims to inspire students pursuing research careers in toxicology and related biomedical sciences. Participants will engage with professionals, attend sessions, and explore various educational and career paths. SOT emphasizes inclusiveness, encouraging diverse perspectives to enhance innovation in the field.

The John Wells Memorial Scholarship, established by the Muskingum County Community Foundation, honors the legacy of John Wells, a dedicated pitching coach. This one-time, non-renewable scholarship supports outstanding female softball players from a six-county area pursuing higher education. Candidates must demonstrate exceptional athletic involvement and commitment to academic success. The scholarship aims to provide financial assistance for tuition, room, and other educational expenses, continuing John's mission of empowering young athletes.

Samsung Solve For Tomorrow

The Samsung Solve for Tomorrow competition asks students to consider how science, technology, engineering, and math (STEM) can be used to create change in their communities. With the help of their teachers, students compete to win up to $100,000 in prizes for their school, plus the opportunity to work with Samsung employees to develop their innovations. 

Guidelines

Your teacher will apply on behalf of your team by answering these five questions, each in 1,000 characters or less.

• Describe the community challenge or issue you are planning to tackle.
• How will STEM be applied to address this challenge or issue?
• What is the anticipated impact to your local community?
• What activities will you put in place to achieve your goals?
• How will you define and measure success?

Your solution may go through many iterations as you test and refine the idea, but the problem you are solving should remain the same throughout the competition. .

Once your teacher submits your team’s application, the fun begins! Get to work building your solution, gathering data, and iterating as you go. 

Helpful Tips

• Choose a problem that you and your classmates are truly passionate about solving.
• Pick a topic that's manageable for your team and realistic to execute within the bounds of the competition. Feasibility is included in the judges’ scoring rubric.
• Consider the audience you are developing a solution for and get their input as you work.
• Leverage your local community. See if you can connect with your town government or other leaders in your area to get them invested in and excited about your project.
• Remember to back up any claims with facts and statistics.

Reasons to get involved

• Prizes for your school range from $1,000 all the way up to $100,000.
• Community recognition: Samsung Solve for Tomorrow participants and winners are frequently featured in the local news.
• Build crucial skills in areas like public speaking, critical thinking, and entrepreneurship.
• Collaborate with your peers on a project you feel passionate about.
• Help your community become a better place with your innovative thinking.
• Through the Solve for Tomorrow competition, educators can teach Problem-Based Learning (PBL) by challenging students to find solutions in their communities. 

Pediatric Dermatology Research Alliance Inc 

PHACE syndrome is a neurocutaneous syndrome characterized by large segmental infantile hemangiomas of the face and scalp in association with congenital anomalies that may affect the posterior fossa of the brain, cerebral and cervical arteries, heart, and/or eyes. LUMBAR syndrome is the lower-body counterpart of PHACE, characterized by large segmental infantile hemangiomas of the lumbosacral, buttock or pelvic regions associated with urogenital, spinal, bony, anorectal, and/or renal abnormalities. Those affected experience a wide range of comorbidities with significant psychosocial impact. We invite proposals for clinical research that improves diagnostic approaches, enhances quality of life, and addresses key aspects of disease burden and management.

Applications may be submitted by either a single investigator or multiple investigators at multiple institutions. A total of $40,000 is available and may be awarded as one large-scale project or as multiple smaller awards, depending on the number and quality of applications received. Equal consideration will be given to projects in either of the two award formats with decisions to be based upon merit and available funds.

Focus

Research should focus on PHACE and/or LUMBAR syndromes. Priority will be given to investigators who have not previously served as the senior investigator on an R01 NIH grant or equivalent, and to studies that include multidisciplinary teams with active roles for early-career investigators. Proposals that meaningfully integrate patient perspectives are strongly encouraged.

Important Details

• Up to $40,000 will be funded to support one large-scale project for up to two years, or as multiple awards for smaller-scale projects

The American Academy of Audiology offers the Investigator Research Grant to promote essential research in audiology and balance health care. With a funding limit of $20,000 for one-year projects, the grant aims to support innovative research that enhances the evaluation and management of hearing and balance disorders. Eligible applicants must hold a doctoral degree in audiology or hearing science and be affiliated with a non-profit institution in the U.S. or Canada, fostering collaboration between academia and clinical practice.

The Anne Gilbert Visual Arts Scholarship, offered by the Muskingum County Community Foundation, aims to support undergraduate college sophomores pursuing studies in fine arts, graphic design, art and design, or fashion design. Applicants must be residents of Muskingum County, have completed their freshman year, and maintain a GPA of 2.5 or higher. This scholarship encourages artistic development and community engagement, allowing students to further their education and creative pursuits.

The FY 2026 funding opportunity aims to support Indian Tribes and intertribal consortia in implementing approved Nonpoint Source management programs under the Clean Water Act Section 319. This initiative, funded by the EPA, focuses on addressing NPS pollution through best management practices as outlined in Tribal NPS Management Program Plans, ensuring the protection of water resources and promoting sustainability in Tribal lands.

The SHC Student Research Grant supports research utilizing herbarium resources across various taxa, including plants, fungi, lichens, and algae. Eligible projects may involve fieldwork, data collection, or meta-analysis of herbarium data, with an emphasis on enhancing herbarium collections. Three grants are awarded annually: two for $500 and one specifically for undergraduates for $250. Applicants must be student SHC members with projects likely to lead to publication.

The Lam Research Core Values Scholarship, offered by the East Bay Community Foundation, supports high school seniors from specific districts in California and Oregon. Recipients are awarded $10,000 over four years, promoting educational success. Eligible students must exemplify Lam's Core Values, maintain a GPA of 2.7 or higher, and plan to attend a college or technical school. This scholarship aims to empower diverse youth in their educational pursuits and foster community development.

The Robert Graves Art Scholarship honors a dedicated educator and artist, Robert Graves, who passionately supported young artists. Open to students from Chelan, Douglas, and Okanogan counties pursuing higher education in visual arts, this scholarship encourages creativity and artistic growth. Applicants must maintain a minimum GPA of 3.0 and submit original artwork. This initiative not only fosters individual talent but also contributes to the cultural enrichment of the community.

The Action, Implementation, and Mitigation (AIM) Grants, offered by COCO, support organizations in enhancing wildfire risk reduction efforts. Since 2018, COCO has assisted over 90 groups, focusing on community resilience and restoration of fire-adapted ecosystems. Eligible applicants include nonprofits and local governments, with funding ranging from $10,000 to $75,000. Projects should align with broader wildfire strategies and require a 100% cash or in-kind match, promoting inclusive and effective community mitigation approaches.

The VCRC-VF Fellowship Program, a collaboration between the Vasculitis Clinical Research Consortium and the Vasculitis Foundation, offers a two-year mentored training opportunity for physician-investigators dedicated to vasculitis research. This tailored fellowship allows candidates to gain clinical and translational research experience at VCRC-affiliated sites in North America, focusing on patient-oriented investigation. Applicants must hold an MD, demonstrate a commitment to vasculitis care, and ideally possess relevant subspecialty training.

The Remsberg-Trout Scholarship Fund supports local students pursuing STEM degrees. One scholarship assists a senior from Williamsport High School, while two additional scholarships are available for graduates from other Washington County public high schools. All applicants must be members of the National Honor Society. This initiative, part of the Community Foundation of Washington County, MD, aims to foster educational opportunities and enhance the community's future.