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Best Custer County Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in Custer County, South Dakota? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$3.26B

Total funding

$5K

Median grant

9,000+ grants
$3.26B total
$5K median

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9,006 Results based on applied filters

Engineering (ENG): Electrical, Communications, and Computing Systems (ECCS) (363613)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Science Foundation (NSF) Directorate for Engineering (ENG) fosters groundbreaking research in electrical, communications, and computing systems through programs like Electronic, Photonic, Magnetic, and Quantum Devices (EPMQD) and Circuits and Systems for Communications and Sensing (CSCS). These initiatives emphasize innovative foundational research, particularly in power and energy systems, while being open to transformative ideas without immediate commercial outcomes. Funding availability will shape the portfolios of ECCS awards.
Electrical Engineering Computer Science & Engineering Engineering

MPS Mathematical Sciences Research Programs (MPS MathSci)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The MPS Mathematical Sciences Research Programs (MPS MathSci) by the NSF supports diverse research initiatives in theoretical and applied mathematical sciences. Key areas include Algebra, Applied Mathematics, Combinatorics, and Mathematical Biology. The program encourages groundbreaking foundational research with flexible budgets and durations. Proposals do not need to promise immediate outcomes, allowing researchers to explore innovative concepts without the pressure of commercial viability.
Mathematics Science Physics

Core Research in Biological Sciences (BIO Core)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NSF Core Research in Biological Sciences (BIO Core) program supports innovative research that enhances our understanding of biological systems, from molecular to biome scales. This funding opportunity encourages interdisciplinary proposals and can fund both single and multi-investigator projects. The awards will vary in scope and duration, accommodating exploratory projects and long-term commitments, depending on available funding and alignment with the program's objectives.
Science Biology Molecular Biology

Fiscal Year (FY) 2026 Funding Opportunity for Indian Tribes and Intertribal Consortia for Nonpoint Source Management Grants Under Clean Water Act Section 319

United States Environmental Protection Agency (EPA)
Federal Government
United States
Up to US $175,000
The FY 2026 funding opportunity aims to support Indian Tribes and intertribal consortia in implementing approved Nonpoint Source management programs under the Clean Water Act Section 319. This initiative, funded by the EPA, focuses on addressing NPS pollution through best management practices as outlined in Tribal NPS Management Program Plans, ensuring the protection of water resources and promoting sustainability in Tribal lands.
Sanitation & Clean Drinking Water Native American Services Indigenous Services

MPS Physics Research Programs (MPS Physics)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The MPS Physics Research Programs, funded by the National Science Foundation (NSF), support transformative research in various fields of physics. This includes experimental and theoretical work in atomic and molecular physics, particle physics, gravitational physics, and more. The NSF aims to promote ambitious projects without the need for immediate commercialization, focusing instead on foundational advancements that push the boundaries of our understanding of the universe.
Physics Astronomy & Astrophysics Geophysics

Engineering (ENG): Civil, Mechanical and Manufacturing Innovation (CMMI)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Science Foundation (NSF) is offering funding through the Engineering (ENG) program, focusing on foundational research in civil, mechanical, and manufacturing innovation. Key areas include advanced manufacturing systems, civil infrastructure, and intelligent dynamic systems. The NSF ENG encourages innovative and transformative proposals that may not require immediate commercial outcomes. Award sizes and durations will vary based on budget availability, aiming to support long-term research advancements.
Engineering Manufacturing Engineering Mechanical Engineering

MPS Astronomical Sciences Research Programs (MPS Astro)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The MPS Astronomical Sciences Research Programs, funded by the National Science Foundation, support innovative research in astronomical sciences. These initiatives aim to enhance our understanding of the universe through core research, technological advancements, and instrumentation. Topics include solar storm prediction, the discovery of exoplanets, and the study of black holes. Proposals should reflect ambitious, transformative ideas that may not require immediate practical outcomes, fostering long-term scientific exploration.
Astronomy & Astrophysics Astrobiology

Expeditions in Computing (Expeditions)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NSF Expeditions in Computing program aims to foster transformative research in computer and information science. By funding projects up to $15 million over seven years, it encourages multidisciplinary teams to tackle ambitious research agendas that redefine the future of computing. The program supports innovative areas such as new architectures for intelligence, advanced robotics, and next-generation communication, emphasizing the importance of collaboration across various fields to achieve groundbreaking advancements.
Data Science & Digital Information Systems Cyberinfrastructure

Literary Arts Project Grants

South Arts, Inc.
Private
United States
Up to US $5,000

Literary Arts Project Grants

As part of its Literary Arts Initiative, South Arts is pleased to announce Literary Arts Project Grants supporting literary arts organizations and small presses that focus on contemporary literary arts.

These grants advance South Arts’ commitment to amplifying the literary traditions and artistic practices of the American South by directly supporting the development, production, and public engagement of high-quality literary projects.

Literary Arts Project Grants support projects in poetry, fiction, creative or literary nonfiction, young readers’ literature, and drama (scriptwriting). Projects must demonstrate artistic excellence, editorial rigor, and meaningful public or community impact.

Award Amount

South Arts will award up to $5,000 per project to eligible literary arts organizations and small presses.

Writing & Literature Poetry Documentaries

The Hendrix-Murphy Book Award

Hendrix-Murphy Foundation
Association/Society
United States
Unspecified amount

Hendrix-Murphy Foundation

Enhancing literature & language at Hendrix College since 1978.

In homage to Bertie Wilson Murphy’s passion for the study and appreciation of literature and language, the Hendrix-Murphy Foundation at Hendrix College was founded in 1978 with an endowment by her son, Charles H. Murphy, Jr., former CEO of Murphy Oil Corporation. Mrs. Murphy was a 1905 graduate of Galloway Women’s College in Searcy, Ark., which merged with Hendrix College in Conway in the 1930s. Charles H. Murphy, Jr., was a member of the Hendrix Board of Trustees and served as chair. 

The Foundation's programs are overseen by a Board of Directors that is headed by the president of the College and includes Murphy family members, the provost, and representatives from the Hendrix Board of Trustees.

The Hendrix-Murphy Book Award

Hendrix is proud to offer the Hendrix-Murphy Book Award to an outstanding high school junior who demonstrates distinguished scholarship or leadership in literary studies (English, creative writing, foreign languages, or drama).

Hendrix-Murphy Book Award recipients will receive a copy of Poems to Read: A New Favorite Poems Anthology, edited by Robert Pinsky and Maggie Dietz.

Students may be nominated by their English, languages, creative writing, or drama teacher or guidance counselor by using the required form.

Writing & Literature Linguistics Language Education +1 more

1890 Institution Teaching, Research, and Extension Capacity Building Grants Program (363796)

USDA: National Institute of Food and Agriculture (NIFA)
Federal Government
United States
US $50,000 - US $750,000
The 1890 Institution Teaching, Research, and Extension Capacity Building Grants Program aims to enhance the capabilities of eligible institutions by fostering collaboration with federal and non-federal entities. This initiative supports the White House's commitment to promote excellence at Historically Black Colleges and Universities (HBCUs). By strengthening institutional teaching, research, and extension capacities, the program helps ensure that HBCUs can effectively contribute to innovative solutions in education and community development.
Education - Higher Education Agriculture Workforce Preparation & Job Readiness +1 more

Cancer Prevention and Control Programs for State, Territorial, and Tribal Organizations (363814)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The Cancer Prevention and Control Programs aim to enhance cancer outcomes by funding partnerships among national, state, territorial, and tribal organizations. These initiatives focus on evidence-based strategies for cancer surveillance, prevention, and control, specifically targeting breast and cervical cancer screening for underserved populations. Through collaboration, the program seeks to improve clinical services and cancer survivorship, ultimately striving towards the vision of 'All People Free of Cancer' by leveraging resources and community involvement.
Cancer / Oncology Epidemiology & Public Health Health Care Access & Delivery +2 more

NIH Director's New Innovator Award (DP2 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $475,000
The NIH Director's New Innovator Award supports creative early-stage investigators pursuing innovative research with transformative potential for science relevant to the NIH mission. Applications are encouraged across all NIH-related fields, enhancing support for emerging talent. This award is part of the NIH Common Fund's High-Risk, High-Reward Research Program, which aims to cultivate groundbreaking research and foster the next generation of scientists.
Health & Medicine Medical Education & Professional Training Emerging Technology Development

Residential Treatment for Pregnant and Postpartum Women

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Residential Treatment for Pregnant and Postpartum Women program aims to deliver essential services to women facing substance use disorders. By offering comprehensive residential treatment options, the program supports both recovery and the well-being of mothers and their children. Funded by the Substance Abuse and Mental Health Services Administration, this initiative addresses the unique challenges of pregnant and postpartum women, ensuring they receive the care necessary for a successful recovery journey.
Addiction & Substance Use Disorders Drug Use Disorder Women's Health +2 more

Providers Clinical Support System – Universities

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Providers Clinical Support System – Universities program aims to equip graduate-level health professional students with the necessary skills to understand, identify, intervene, and treat patients with substance use disorders. By focusing on practical training and comprehensive education, this initiative prepares future practitioners to effectively address the challenges associated with substance misuse, ensuring they are well-prepared upon obtaining their licenses.
Education - Higher Education Workforce Preparation & Job Readiness Addiction & Substance Use Disorders +1 more

NIH Director's Pioneer Award (DP1 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $700,000
The NIH Director's Pioneer Award (DP1) encourages innovative research by funding exceptional scientists. This award is designed for groundbreaking projects that diverge from the investigator's current work and address significant scientific challenges relevant to the NIH mission. Applications are invited across all NIH-relevant fields, promoting high-risk, high-reward research that could transform our understanding of critical scientific areas.
Science Health & Medicine Emerging Technology Development

NIH Director's Early Independence Award (DP5 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $350,000
The NIH Director's Early Independence Award empowers exceptional early-career researchers to embark on independent research careers immediately after their doctoral degree or post-graduate clinical training. This initiative accelerates the transition to independence, promoting innovative research across various fields aligned with the NIH mission. As part of the NIH Common Fund's High-Risk, High-Reward Research Program, it encourages groundbreaking studies that could significantly advance health-related knowledge.
Science Health & Medicine Medical Education & Professional Training +1 more

NIH Director's Transformative Research Award (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Director's Transformative Research Award encourages innovative research that challenges conventional ideas. This award supports bold scientists and teams aiming to create groundbreaking technologies and new clinical approaches, ultimately transforming scientific paradigms. As part of the NIH Common Fund's High-Risk, High-Reward Research Program, it seeks to fund high-impact projects that have the potential to significantly advance science and technology.
Science Health & Medicine Emerging Technology Development

Emergency Department Alternatives to Opioids Program

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Emergency Department Alternatives to Opioids Program aims to implement practices that offer alternatives to opioid treatments in hospitals. This initiative focuses on reducing the harmful consequences of opioid use for pain management, promoting safer treatment options, and minimizing the risk of opioid misuse and overdose. Specifically, it targets healthcare organizations to enhance their pain care strategies, ultimately contributing to better patient safety and health outcomes.
Addiction & Substance Use Disorders Health Care Access & Delivery Preventative Healthcare

GLS Campus Suicide Prevention (363809)

Substance Abuse and Mental Health Services Adminis
Federal Government
United States
Unspecified amount
The GLS Campus Suicide Prevention program aims to enhance behavioral health services for college students, addressing critical issues such as suicide, depression, and substance use disorders. By fostering a culture of help-seeking and reducing stigma, this initiative ensures that at-risk students receive timely intervention and support. The program represents a vital investment in the mental well-being of students, promoting a healthier campus environment through evidence-based strategies and comprehensive public health approaches.
Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders Health Care Access & Delivery +1 more

State Pilot Program for Treatment for Pregnant and Postpartum Women (363808)

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The State Pilot Program for Treatment for Pregnant and Postpartum Women aims to enhance the state's capacity to deliver integrated and evidence-based services for substance use disorders and maternal mental health. The initiative focuses on supporting pregnant and postpartum women and their families, ensuring they receive comprehensive care tailored to their unique needs. Funded by the Substance Abuse and Mental Health Services Administration, this program is a vital step toward improving health outcomes for vulnerable populations.
Mental Health & Psychiatric Diseases Family Services Addiction & Substance Use Disorders +2 more

Assisted Outpatient Treatment (363811)

US HHS: Substance Abuse and Mental Health Services Administration (SAMHSA)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Assisted Outpatient Treatment (AOT) program aims to support adults with serious mental illness (SMI) by facilitating community-based treatment. Funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), the initiative encourages collaboration with civil courts and community partners. Recipients will implement AOT to ensure that eligible individuals receive necessary support, thereby enhancing their mental health outcomes and promoting recovery.
Community Services Disability Care & Services Mental Health & Psychiatric Diseases +2 more

Building Communities of Recovery (363810)

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Building Communities of Recovery program aims to enhance access to long-term recovery support for individuals facing substance use disorders and co-occurring mental health issues. By empowering organizations to mobilize community resources, this initiative fosters a collaborative environment that promotes sustained recovery. Funded by the Substance Abuse and Mental Health Services Administration, the program emphasizes the importance of community connections in the recovery process, ensuring that individuals receive the support they need to thrive.
Community Services Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders +1 more

Diversity Leadership Fellowship

American Psychiatric Association Foundation
Private
United States
Unspecified amount

American Psychiatric Association Foundation

There is no health without mental health. The APA Foundation is working in your community to provide the support and resources we all need to prioritize mental wellbeing where you live, learn, work, worship, and play.

Backed by the medical expertise of the APA and industry-leading strategic partners, we administer community-changing programs, public education campaigns, grants, and awards aimed at increasing mental health literacy, connecting individuals to needed care, and shifting attitudes toward mental health.

Our Mission is to promote the mental health and well-being of individuals and communities. Our Vision is a mentally healthy nation for all – where we live, learn, work, worship, and play.

Diversity Leadership Fellowship

The Diversity Leadership Fellowship identifies and motivates minority psychiatry residents or those interested in minority and vulnerable populations to become well equipped to teach, administer, and provide culturally competent, evidence based mental health and substance abuse services to diverse minority groups and at-risk populations. These populations include—but are not limited to—American Indians/Native Alaskans, Asian Americans/Native Hawaiians/Native Pacific Islanders, Blacks/African Americans, Hispanics/Latinos, LGBTQ, and religious minorities. Program Benefits:

  • Sponsorship to attend a minimum of four APA meetings:
    • Two APA Annual Meetings
    • Two Fellowship Forums
  • Develop leadership skills in the field of psychiatry and advance understanding of the life experiences of racial ethnic minority communities
  • Gain an understanding of APA/APAF Governance through observation and service on an APA Council, Committee, or APAF initiative
  • Have the opportunity to sit on the APAF Board of Directors as a non-voting member (one Diversity Leadership fellow allowed)
  • Cultivate a professional network with psychiatrists interested in minority mental health and services through exclusive events and engagements with APA leaders. Establish relationships and peer-mentorship with a diverse group of resident fellows with similar career interests and goals
Medical Education & Professional Training Mental Health & Psychiatric Diseases Diversity, Equity & Inclusion

EdTA Membership Grant

Educational Theatre Foundation (EdTA)
Association/Society
United States
Unspecified amount

Building a global community of creative problem solvers, effective collaborators, and empathetic individuals through theatre

Our Mission and Goals

The Educational Theatre Foundation (ETF) is the philanthropic arm of the Educational Theatre Association (EdTA).

ETF advances the field of educational theatre by broadening representation and increasing access for all. ETF’s programs aim to support students, educators and the field at large by realizing three strategic goals:

  • Subsidizing new, emerging, and underserved student theatre programs;
  • Creating paths for theatre educators to develop new skills; and
  • Commissioning research to showcase the value of a theatre education.

Grants for Educators & Theatre Programs

A core piece of the Educational Theatre Foundation’s work is supporting theatre educators and theatre programs directly. We do this through a series of production and educator grants available to both members of EdTA as well as non-members.

EdTA Membership Grant

Theatre matters.

It belongs in our classrooms and communities – now more than ever. Yet the role of the theatre educator has become increasingly complex, and financial support is often uncertain or even eliminated.

To help meet this moment, the Educational Theatre Foundation is proud to introduce the EdTA Membership Grant.

Theater Teacher Development & Training

Pink Gravel Fund

Emporia Community Foundation
Private
United States
Up to US $500

About the Emporia Community Foundation

Our Mission

To connect caring people with causes that build stronger communities within the Emporia area which includes Chase, Coffey, Greenwood, Lyon, Morris, Osage and Wabaunsee counties.

Pink Gravel Fund

The purpose of the Pink Gravel Fund is to provide funds to qualified individuals to cover expenses related to the treatment and recovery of breast cancer. 

Breast Cancer Health Care Access & Delivery

BBDF Research Grant

Beyond Batten Disease Foundation (BBDF )
Association/Society
Countries
US $5,000 - US $2,000,000

About the Foundation

Our Mission

Beyond Batten Disease Foundation was established to eradicate juvenile Batten disease by raising awareness and funds to accelerate research for a treatment or cure.

About Funding

BBDF is dedicated to collaboratively developing, funding, and managing fundamental, preclinical, IND-enabling, translational and clinical research to improve the lives of children and young adults with CLN3 disease. Since 2008, BBDF has been the largest funder of juvenile Batten (CLN3) disease research, ranging from basic discovery research to translation into therapies. To inform our research initiatives, BBDF gathers information from one-on-one meetings, broad group discussions, scientific peer-reviewed publications, conference proceedings, drug pipelines, and tailored merit reviews into the foundation’s decision-making processes. Input comes from across the Research and Development spectrum including academia, biotechnology, the pharmaceutical sector, and clinicians, caregivers, and patients.

Our research funding decisions are based on these research objectives:

1) Supporting basic research to discover new mechanisms of disease, targets, and treatments

2) Supporting projects which facilitate execution of clinical trials such as expanding patient registries

3) Identifying biomarkers and other innovative clinical endpoints

4) Supporting projects that de-risks pharmaceutical investments in Batten disease

Foundation-Directed Research

The largest portion of the foundation’s portfolio is directed research. The foundation fills gaps in juvenile Batten disease research by funding high-impact projects and breakthrough technologies that will lead to disease mitigation and cure.

BBDF’s Principal Scientist regularly interacts with leaders in research and development across the entire therapeutic pipeline for Batten, as well as for adult forms of neurodegeneration (e.g., Alzheimer’s and Parkinson’s disease), and other related rare genetic diseases. To supplement this dialogue, BBDF creates specialty boards and steering committees to lead the development of its projects. A specialty board typically comprises ~200 years of combined experience specific to the proposed activity.

Investor-Initiated Research (Applying for a research grant)

In addition to directed research, BBDF accepts and awards research proposals. Because great ideas do not follow a schedule, we do this on a rolling submission basis. All budgets are carefully reviewed along with the proposed body of work. Applicants may be asked to revise their budgets and/or allow BBDF to share a summary of the proposal with other funders for the purpose of gathering additional support. Sometimes, the foundation will offer the applicant additional funding to incorporate additional expertise or methods into his or her plan.

Rare Diseases Children’s Health & Pediatrics

Custer County Grants for Nonprofits Highlights

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Read more about each grant below or start your 14-day free trial to see all Custer County grants recommended for your specific programs in South Dakota.

Grant Insights : Grant Funding Trends in South Dakota

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Custer County Grants for Nonprofits year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Custer County Grants for Nonprofits given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Custer County Grants for Nonprofits changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538