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Best Des Moines Grants for Nonprofits in Iowa

Looking for grants for 501(c)(3) nonprofit organizations working in Des Moines, Iowa? Find the perfect grant for your nonprofit on Instrumentl.

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$2.57B

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$5K

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9,000+ grants
$2.57B total
$5K median

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9,115 Results based on applied filters

AHCJ Sunshine Award

Association of Health Care Journalists (AHCJ)
Association/Society
United States
Unspecified amount

About

Building a community of journalists committed to better health care reporting.

We believe accurate, contextual and balanced health care reporting is more important than ever.

People depend on health care stories to make life-altering decisions every day.

Awards, Grants, & Fellowships

Ambitious freelancers who want to tackle an in-depth reporting project often find that the fee from a potential publisher doesn’t come close to covering their costs and time. Grants and fellowships can fill that gap, but freelancers have to know about them in order to apply. In this section, the Freelance Center is compiling a list of non-AHCJ grants, fellowships and awards (for when the hard work is done).

Sunshine Award

Presented by AHCJ’s Right-to-Know Committee

AHCJ’s Right-to-Know Committee established the Sunshine Award at Health Journalism 2026 as a way to elevate the work of journalists like STAT’s Bob Herman who fight for government transparency. We plan to continue this tradition annually from now on. Award winners receive free registration and a one-night hotel stay for our annual conference, a free year of AHCJ membership, a trophy and a certificate.

Journalism Epidemiology & Public Health Health Policy & Advocacy +2 more

Visual Arts & Education Grant

Helen Frankenthaler Foundation Inc
Private
United States
US $5,000 - US $100,000

Helen Frankenthaler Foundation Inc

The Helen Frankenthaler Foundation supports the artist’s legacy through a variety of initiatives, including exhibitions, loans of artworks, research and publications, conservation, grants, educational programs for the public and the scholarly community, and the publishing of a catalogue raisonné. It is dedicated to promoting greater public interest in and understanding of the visual arts.

Established and endowed by the artist during her lifetime (1928-2011), the Foundation became active in 2013, on the closing of Frankenthaler’s estate. As the principal beneficiary of Frankenthaler’s estate, the Foundation maintains an extensive collection of her work in a variety of mediums, as well as her collection of works by other artists and original papers and materials pertaining to her life and work.

Visual Arts & Education Grant

The Helen Frankenthaler Foundation supports public engagement with the visual arts through philanthropic, educational, curatorial, and research initiatives. It has expanded its grantmaking to sustain museums and visual arts institutions, supporting exhibitions, scholarship, and education across the field. The Foundation’s grantmaking priorities are currently organized across three areas:

  • Climate Action and Sustainability
  • Cultural Resilience
  • Visual Arts & Education
    • Project-based support for exhibitions, publications, public programs, and academic initiatives that advance the presentation, study, and interpretation of the visual arts.
    • The Foundation supports discrete, institutionally grounded projects that advance the presentation, study, and understanding of the visual arts. Competitive proposals typically include:
      • Exhibitions, publications, and public programs focused on modern and contemporary art
      • Projects that expand access to collections, archives, and curatorial research
      • Academic and institutional initiatives in art history, studio practice, visual studies, museum and curatorial studies, conservation, and related areas of scholarship and teaching—particularly those involving university museums, galleries, and special collections
      • Conferences, programs, or initiatives led by professional organizations whose missions address the visual arts
      • Exhibitions and scholarly or public programs related to the 2028 centennial of Helen Frankenthaler
      • Projects must be clearly defined in scope, duration, and outcomes, and supported by appropriate institutional capacity. Requests for Visual Arts & Education funds should not be framed as general operating support. 
Education Visual Arts

Cultural Resilience Grant

Helen Frankenthaler Foundation Inc
Private
United States
US $5,000 - US $100,000

Helen Frankenthaler Foundation Inc

The Helen Frankenthaler Foundation supports the artist’s legacy through a variety of initiatives, including exhibitions, loans of artworks, research and publications, conservation, grants, educational programs for the public and the scholarly community, and the publishing of a catalogue raisonné. It is dedicated to promoting greater public interest in and understanding of the visual arts.

Established and endowed by the artist during her lifetime (1928-2011), the Foundation became active in 2013, on the closing of Frankenthaler’s estate. As the principal beneficiary of Frankenthaler’s estate, the Foundation maintains an extensive collection of her work in a variety of mediums, as well as her collection of works by other artists and original papers and materials pertaining to her life and work.

Cultural Resilience Grant

The Helen Frankenthaler Foundation supports public engagement with the visual arts through philanthropic, educational, curatorial, and research initiatives. It has expanded its grantmaking to sustain museums and visual arts institutions, supporting exhibitions, scholarship, and education across the field. The Foundation’s grantmaking priorities are currently organized across three areas:

  • Climate Action and Sustainability
  • Visual Arts & Education
  • Cultural Resilience
    • Unrestricted support to sustain institutional capacity and core programming across the visual arts field. 
    • The Foundation provides unrestricted support to organizations whose core work is centered in the visual arts. These grants are intended to sustain exhibitions, programs, and institutional activities; support staffing, operations, and organizational capacity; and to maintain continuity during periods of reduced public funding and broader pressures affecting the arts and culture sector.
      • Cultural Resilience support is not project-based and does not require a defined initiative. 
Visual Arts Museums & Cultural Institutions

Engineering (ENG): Electrical, Communications, and Computing Systems (ECCS) (363613)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Science Foundation (NSF) Directorate for Engineering (ENG) fosters groundbreaking research in electrical, communications, and computing systems through programs like Electronic, Photonic, Magnetic, and Quantum Devices (EPMQD) and Circuits and Systems for Communications and Sensing (CSCS). These initiatives emphasize innovative foundational research, particularly in power and energy systems, while being open to transformative ideas without immediate commercial outcomes. Funding availability will shape the portfolios of ECCS awards.
Electrical Engineering Computer Science & Engineering Engineering

MPS Mathematical Sciences Research Programs (MPS MathSci)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The MPS Mathematical Sciences Research Programs (MPS MathSci) by the NSF supports diverse research initiatives in theoretical and applied mathematical sciences. Key areas include Algebra, Applied Mathematics, Combinatorics, and Mathematical Biology. The program encourages groundbreaking foundational research with flexible budgets and durations. Proposals do not need to promise immediate outcomes, allowing researchers to explore innovative concepts without the pressure of commercial viability.
Mathematics Science Physics

Core Research in Biological Sciences (BIO Core)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NSF Core Research in Biological Sciences (BIO Core) program supports innovative research that enhances our understanding of biological systems, from molecular to biome scales. This funding opportunity encourages interdisciplinary proposals and can fund both single and multi-investigator projects. The awards will vary in scope and duration, accommodating exploratory projects and long-term commitments, depending on available funding and alignment with the program's objectives.
Science Biology Molecular Biology

Fiscal Year (FY) 2026 Funding Opportunity for Indian Tribes and Intertribal Consortia for Nonpoint Source Management Grants Under Clean Water Act Section 319

United States Environmental Protection Agency (EPA)
Federal Government
United States
Up to US $175,000
The FY 2026 funding opportunity aims to support Indian Tribes and intertribal consortia in implementing approved Nonpoint Source management programs under the Clean Water Act Section 319. This initiative, funded by the EPA, focuses on addressing NPS pollution through best management practices as outlined in Tribal NPS Management Program Plans, ensuring the protection of water resources and promoting sustainability in Tribal lands.
Sanitation & Clean Drinking Water Native American Services Indigenous Services

MPS Physics Research Programs (MPS Physics)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The MPS Physics Research Programs, funded by the National Science Foundation (NSF), support transformative research in various fields of physics. This includes experimental and theoretical work in atomic and molecular physics, particle physics, gravitational physics, and more. The NSF aims to promote ambitious projects without the need for immediate commercialization, focusing instead on foundational advancements that push the boundaries of our understanding of the universe.
Physics Astronomy & Astrophysics Geophysics

Engineering (ENG): Civil, Mechanical and Manufacturing Innovation (CMMI)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Science Foundation (NSF) is offering funding through the Engineering (ENG) program, focusing on foundational research in civil, mechanical, and manufacturing innovation. Key areas include advanced manufacturing systems, civil infrastructure, and intelligent dynamic systems. The NSF ENG encourages innovative and transformative proposals that may not require immediate commercial outcomes. Award sizes and durations will vary based on budget availability, aiming to support long-term research advancements.
Engineering Manufacturing Engineering Mechanical Engineering

MPS Astronomical Sciences Research Programs (MPS Astro)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The MPS Astronomical Sciences Research Programs, funded by the National Science Foundation, support innovative research in astronomical sciences. These initiatives aim to enhance our understanding of the universe through core research, technological advancements, and instrumentation. Topics include solar storm prediction, the discovery of exoplanets, and the study of black holes. Proposals should reflect ambitious, transformative ideas that may not require immediate practical outcomes, fostering long-term scientific exploration.
Astronomy & Astrophysics Astrobiology

Expeditions in Computing (Expeditions)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NSF Expeditions in Computing program aims to foster transformative research in computer and information science. By funding projects up to $15 million over seven years, it encourages multidisciplinary teams to tackle ambitious research agendas that redefine the future of computing. The program supports innovative areas such as new architectures for intelligence, advanced robotics, and next-generation communication, emphasizing the importance of collaboration across various fields to achieve groundbreaking advancements.
Data Science & Digital Information Systems Cyberinfrastructure

EMERGING FRONTIERS IN RESEARCH AND INNOVATION (EFRI-2026/27): Wave-Based Computing ( EFRI-WBC)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
US $100,000 - US $2,000,000
The Emerging Frontiers in Research and Innovation (EFRI) program by the NSF aims to support transformative research in wave-based computing, fostering significant advancements in foundational engineering knowledge. With funding opportunities including EAGER awards and four-year grants up to $2 million, EFRI-WBC encourages interdisciplinary collaboration and innovative approaches to address strategic technology priorities. Proposals should articulate their potential long-term impacts on national science and technology missions, promoting a new era in computing methodologies.
Engineering

MPS Chemistry Research Programs (MPS Chem)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NSF MPS Chemistry Research Programs support groundbreaking research in chemical sciences, encompassing areas such as chemical catalysis, measurement, imaging, and theory. This initiative encourages innovative proposals that can lead to transformative advancements, without the necessity of immediate commercial applications. Researchers interested in exploring foundational concepts that could shape the future of chemistry are invited to submit their ideas for funding.
Chemistry Biochemistry Geochemistry & Biogeochemistry +1 more

Engineering (ENG): Chemical, Bioengineering, Energy, and Transport Systems (CBET)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Science Foundation's Engineering Directorate (NSF ENG) promotes groundbreaking research in chemical, bioengineering, energy, and transport systems. Key programs include Chemical Process Systems, Engineering Biological and Biomedical Systems, Energy, Water, and Resource Engineering, and Transport Phenomena. NSF ENG seeks innovative, transformative proposals that push the boundaries of foundational research, regardless of immediate commercial applications, and emphasizes diverse funding opportunities based on availability.
Bioengineering Environmental Engineering

1890 Institution Teaching, Research, and Extension Capacity Building Grants Program (363796)

USDA: National Institute of Food and Agriculture (NIFA)
Federal Government
United States
US $50,000 - US $750,000
The 1890 Institution Teaching, Research, and Extension Capacity Building Grants Program aims to enhance the capabilities of eligible institutions by fostering collaboration with federal and non-federal entities. This initiative supports the White House's commitment to promote excellence at Historically Black Colleges and Universities (HBCUs). By strengthening institutional teaching, research, and extension capacities, the program helps ensure that HBCUs can effectively contribute to innovative solutions in education and community development.
Education - Higher Education Agriculture Workforce Preparation & Job Readiness +1 more

Cancer Prevention and Control Programs for State, Territorial, and Tribal Organizations (363814)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The Cancer Prevention and Control Programs aim to enhance cancer outcomes by funding partnerships among national, state, territorial, and tribal organizations. These initiatives focus on evidence-based strategies for cancer surveillance, prevention, and control, specifically targeting breast and cervical cancer screening for underserved populations. Through collaboration, the program seeks to improve clinical services and cancer survivorship, ultimately striving towards the vision of 'All People Free of Cancer' by leveraging resources and community involvement.
Cancer / Oncology Epidemiology & Public Health Health Care Access & Delivery +2 more

NIH Director's New Innovator Award (DP2 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $475,000
The NIH Director's New Innovator Award supports creative early-stage investigators pursuing innovative research with transformative potential for science relevant to the NIH mission. Applications are encouraged across all NIH-related fields, enhancing support for emerging talent. This award is part of the NIH Common Fund's High-Risk, High-Reward Research Program, which aims to cultivate groundbreaking research and foster the next generation of scientists.
Health & Medicine Medical Education & Professional Training Emerging Technology Development

Residential Treatment for Pregnant and Postpartum Women

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Residential Treatment for Pregnant and Postpartum Women program aims to deliver essential services to women facing substance use disorders. By offering comprehensive residential treatment options, the program supports both recovery and the well-being of mothers and their children. Funded by the Substance Abuse and Mental Health Services Administration, this initiative addresses the unique challenges of pregnant and postpartum women, ensuring they receive the care necessary for a successful recovery journey.
Addiction & Substance Use Disorders Drug Use Disorder Women's Health +2 more

Providers Clinical Support System – Universities

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Providers Clinical Support System – Universities program aims to equip graduate-level health professional students with the necessary skills to understand, identify, intervene, and treat patients with substance use disorders. By focusing on practical training and comprehensive education, this initiative prepares future practitioners to effectively address the challenges associated with substance misuse, ensuring they are well-prepared upon obtaining their licenses.
Education - Higher Education Workforce Preparation & Job Readiness Addiction & Substance Use Disorders +1 more

NIH Director's Pioneer Award (DP1 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $700,000
The NIH Director's Pioneer Award (DP1) encourages innovative research by funding exceptional scientists. This award is designed for groundbreaking projects that diverge from the investigator's current work and address significant scientific challenges relevant to the NIH mission. Applications are invited across all NIH-relevant fields, promoting high-risk, high-reward research that could transform our understanding of critical scientific areas.
Science Health & Medicine Emerging Technology Development

NIH Director's Early Independence Award (DP5 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $350,000
The NIH Director's Early Independence Award empowers exceptional early-career researchers to embark on independent research careers immediately after their doctoral degree or post-graduate clinical training. This initiative accelerates the transition to independence, promoting innovative research across various fields aligned with the NIH mission. As part of the NIH Common Fund's High-Risk, High-Reward Research Program, it encourages groundbreaking studies that could significantly advance health-related knowledge.
Science Health & Medicine Medical Education & Professional Training +1 more

NIH Director's Transformative Research Award (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Director's Transformative Research Award encourages innovative research that challenges conventional ideas. This award supports bold scientists and teams aiming to create groundbreaking technologies and new clinical approaches, ultimately transforming scientific paradigms. As part of the NIH Common Fund's High-Risk, High-Reward Research Program, it seeks to fund high-impact projects that have the potential to significantly advance science and technology.
Science Health & Medicine Emerging Technology Development

Emergency Department Alternatives to Opioids Program

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Emergency Department Alternatives to Opioids Program aims to implement practices that offer alternatives to opioid treatments in hospitals. This initiative focuses on reducing the harmful consequences of opioid use for pain management, promoting safer treatment options, and minimizing the risk of opioid misuse and overdose. Specifically, it targets healthcare organizations to enhance their pain care strategies, ultimately contributing to better patient safety and health outcomes.
Addiction & Substance Use Disorders Health Care Access & Delivery Preventative Healthcare

GLS Campus Suicide Prevention (363809)

Substance Abuse and Mental Health Services Adminis
Federal Government
United States
Unspecified amount
The GLS Campus Suicide Prevention program aims to enhance behavioral health services for college students, addressing critical issues such as suicide, depression, and substance use disorders. By fostering a culture of help-seeking and reducing stigma, this initiative ensures that at-risk students receive timely intervention and support. The program represents a vital investment in the mental well-being of students, promoting a healthier campus environment through evidence-based strategies and comprehensive public health approaches.
Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders Health Care Access & Delivery +1 more

State Pilot Program for Treatment for Pregnant and Postpartum Women (363808)

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The State Pilot Program for Treatment for Pregnant and Postpartum Women aims to enhance the state's capacity to deliver integrated and evidence-based services for substance use disorders and maternal mental health. The initiative focuses on supporting pregnant and postpartum women and their families, ensuring they receive comprehensive care tailored to their unique needs. Funded by the Substance Abuse and Mental Health Services Administration, this program is a vital step toward improving health outcomes for vulnerable populations.
Mental Health & Psychiatric Diseases Family Services Addiction & Substance Use Disorders +2 more

Assisted Outpatient Treatment (363811)

US HHS: Substance Abuse and Mental Health Services Administration (SAMHSA)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Assisted Outpatient Treatment (AOT) program aims to support adults with serious mental illness (SMI) by facilitating community-based treatment. Funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), the initiative encourages collaboration with civil courts and community partners. Recipients will implement AOT to ensure that eligible individuals receive necessary support, thereby enhancing their mental health outcomes and promoting recovery.
Community Services Disability Care & Services Mental Health & Psychiatric Diseases +2 more

Building Communities of Recovery (363810)

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Building Communities of Recovery program aims to enhance access to long-term recovery support for individuals facing substance use disorders and co-occurring mental health issues. By empowering organizations to mobilize community resources, this initiative fosters a collaborative environment that promotes sustained recovery. Funded by the Substance Abuse and Mental Health Services Administration, the program emphasizes the importance of community connections in the recovery process, ensuring that individuals receive the support they need to thrive.
Community Services Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders +1 more

Des Moines Grants for Nonprofits Highlights

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Last updated: October 5, 2026. Next update: November 1, 2026.

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