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Best Des Moines Grants for Nonprofits in Iowa

Looking for grants for 501(c)(3) nonprofit organizations working in Des Moines, Iowa? Find the perfect grant for your nonprofit on Instrumentl.

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$5K

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9,274 Results based on applied filters

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $600,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a funding opportunity for Exploratory Clinical Trials Grants. This program aims to support innovative clinical trials that enhance the understanding and treatment of arthritis and other musculoskeletal and skin conditions. Research proposals should focus on early-stage trials, including first-in-human studies, dose-finding, and biomarker evaluation. The initiative encourages the translation of promising laboratory findings into effective clinical practices, ultimately improving patient outcomes.
Musculoskeletal Diseases Skin Diseases & Dermatology Arthritis

Historical Resource Development Program (HRDP) - Emergency Grant

State Historical Society of Iowa
Association/Society
Iowa
Up to US $15,000

State Historical Society of Iowa

The State Historical Society of Iowa is the official historical repository of the State of Iowa, providing grants, education, and outreach about Iowa’s history.

The society preserves and provides access to Iowa’s historical resources through programs, exhibitions and projects while advocating for Iowa’s past and serving as a connector to the future.

Historical Resource Development Program

The program provides grant funding to help preserve, conserve, interpret, enhance, and educate the public about Iowa’s historical assets. The Historical Resource Development Program provides funding for documentary collections, historic preservation and museums. 

Emergency Historical Resource Development Program

Emergency HRDP applications will be accepted each year on July 1. Funds are limited and awarded on a first-come, first-served basis.

The differences between the regular grant application process and the emergency application process are as follows:

  • Please contact the grants manager by email or phone to see if funds are available.
  • Attach a cover letter that explains the threat to the resource.
  • The threat to the resource cannot be due to delinquency on the part of the current owner.
  • If new ownership is the reason for the emergency, the new owner must have taken ownership within the previous 12 months.
  • The maximum grant request is $15,000.
  • Funds become available at the beginning of each fiscal year, July 1st. There isn’t a specific deadline. Submit the application as soon as it is ready, as long as it is not prior to July 1st if you are requesting funds from the next fiscal year.
  • Grants are awarded on a first-come, first-served basis until all emergency funds for each grant category are expended.
  • A staff grants steering committee reviews the applications. Allow up to 30 days for review.
  • Eligible properties in the historic preservation category will have an opinion of eligibility for listing on the National Register of Historic Places from the State Historic Preservation Office.
Historical Records & Archives Historic Preservation Museums & Cultural Institutions

Angel Post Deployment Test Program

United Negro College Fund Inc
Private
United States
US $5,000 - US $10,000

Angel Post Deployment Test Program

Through a collaborative partnership with UNCF, XYZ Corporation has established a scholarship program to help STEM students get on the fast track to a rewarding career. In addition to direct financial support, Intel-sponsored scholarships offer the benefits of exposure to potential job opportunities, networking with fellow scholars, insight to other Intel scholarships, research, training opportunities, and access to Intel mentors offering support on technical, non-technical, cultural, and dissertation-related needs.

Workforce Preparation & Job Readiness Career / College Preparation

Storytelling Review Grant

Communication Foundation (CF)
Association/Society
Countries
€2,500

Let’s accelerate meaningful change!

Our mission is clear: to accelerate meaningful change through effective communication. We work through four core activities: capacity building, storytelling, services and grant support for NGOs. 

We believe in storytelling that inspires action, builds trust and promotes constructive narratives. 

CF strengthens organisations by building the skills and confidence needed to communicate effectively. 

Why a Communication Foundation?

Many NGOs and UN organisations operate with limited budgets and few staff trained in professional communication. Added to this, shifting politics and growing conservatism create new challenges for their work. To remain resilient and amplify their impact, organisations must strengthen their identity and invest in communication. 

When approached strategically, communication can shift from being a perceived obligation to a powerful opportunity. With the right focus, even limited budgets and capacity can be maximised to create and deliver clear, effective strategies unlocking advocacy, fundraising, and public trust, and ultimately driving meaningful, lasting change where it is most needed.

Storytelling Review – Master your mission’s story

Your story defines how people understand your organisation, its values and its impact. A Storytelling Review helps clarify and strengthen your narrative so it consistently reflects who you are, what you stand for and why your work matters.

CF’s Storytelling Review is a structured review of how your organisation communicates its story across channels and formats. We assess narrative structure, key messages, tone of voice, audience focus and coherence to understand whether your storytelling supports your mission and strategic positioning.

How it helps you

Dry data often fails to inspire action. This review helps you to find the "heart" of your work and communicate it in a way that sticks.

  • Identification of missed opportunities for emotional engagement in your current content;
  • Recommendations for moving from "organisational" talk to "human" stories;
  • Advice on ethical storytelling that empowers beneficiaries rather than just portraying need;
  • Guidance on structuring narratives for different platforms (web, social, reports).

What We Do

  • A clear assessment of narrative strengths and gaps;
  • Identification of inconsistencies and overlaps;
  • Guidance on narrative frameworks and messaging;
  • Provide actionable recommendations to master your story.

Why it matters

NGOs operate in complex and competitive environments, where clarity and credibility are essential. Strong storytelling:

  • Builds trust and emotional connection with stakeholders;
  • Clarifies your organisation’s identity and purpose;
  • Strengthens recognition across programmes and campaigns;
  • Supports consistent communication across teams and platforms.

Over time, stories can get fragmented or can lose their meaning. 

Different projects may tell different versions of your mission, diluting impact. 

A Storytelling Review restores focus and alignment within your communication.

Nonprofit Growth & Development

Washington Goes Purple Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington Goes Purple Scholarship

This scholarship is open to students that reside in Washington County, MD, are continuing their education, and have been affected by substance use.

Addiction & Substance Use Disorders Student Retention & Drop-Out Prevention

Washington County Hospital School of Nursing Alumni Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington County Hospital School of Nursing Alumni Scholarship

Founded by alumni of Washington County Hospital’s School of Nursing, this fund serves to provide scholarships to deserving students who are continuing their education in Nursing.

Education - Higher Education Nursing

Washington County Arts Council, Inc. Foundation Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington County Arts Council, Inc. Foundation Scholarship Fund

The Washington County Arts Council, Inc. welcomes all applicants interested in pursuing a 2- or 4-year degree, or a certificate program, from an accredited educational institution with an emphasis on the arts. All students, including those individuals who have pursued a non-traditional education path, will be considered for this scholarship.

Education - Higher Education Art Education

Washington County 4-H Livestock/Market Sale Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington County 4-H Livestock/Market Sale Scholarship

Established to support post-secondary scholarships to participants in Washington County 4-H Livestock and Market Sale programs.

Education - Higher Education Livestock & Ranching Agricultural Economics +1 more

Washington County 4-H Dairy Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington County 4-H Dairy Scholarship

Established to support post-secondary scholarships to participants in Washington County 4-H dairy programs.

Education - Higher Education Livestock & Ranching Agricultural Economics +1 more

The Tim Moffatt Career Advancement Award

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

The Tim Moffatt Career Advancement Award

This scholarship will be awarded to deserving students who are graduating from a WCPS high school, or are a non-traditional learner with equivalent education, who have been accepted into a trade school/program/apprenticeship, or who have enlisted in the military. 

Education - Higher Education Vocational & Trade Education

Pi-Squared Scholarship

Greater Houston Community Foundation
Private
United States
Unspecified amount

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Pi-Squared Scholarship

Benefiting graduating seniors of Spring ISD (Texas), Klein ISD (Texas), and Houston ISD (Texas).

Education - Higher Education Career / College Preparation

Roger and Barbara Powell Scholarship for Nursing

Greater Houston Community Foundation
Private
United States
Unspecified amount

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Roger and Barbara Powell Scholarship for Nursing

Benefiting rural Texas residents pursuing nursing degrees.

Education - Higher Education Nursing

Silver Eagle Distributors Houston Scholarship

Greater Houston Community Foundation
Private
United States
Unspecified amount

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Silver Eagle Distributors Houston Scholarship

Benefiting dependents of Silver Eagle Distributors Houston employees.

Education - Higher Education Career / College Preparation

Tradition of Excellence Scholarship

Greater Houston Community Foundation
Private
United States
Unspecified amount

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Tradition of Excellence Scholarship

Benefiting dependents of current Perry Homes employees.

Education - Higher Education Career / College Preparation

Strong Family Scholarship

Greater Houston Community Foundation
Private
United States
Unspecified amount

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Strong Family Scholarship

Benefiting graduating high school seniors from charter schools in Houston, TX.

Education - Higher Education Career / College Preparation

Taka Domingo HLP Vocational Scholarship

HLP Hamakua Community Foundation
Association/Society
United States
US $2,000

Taka Domingo HLP Vocational Scholarship

The HLP Hamakua Community Foundation is a non-profit organization that was formed to benefit the people of Hamakua. Taka Domingo was one of the original board members when HLP was established after the closure of sugar. He was an electrician and County Councilman representing the Hamakua District. The Taka Domingo HLP Vocational Scholarship was established after his death in August 2016. 

Individual award amount: $2,000. 

Possible trades include: welding, tourism, fire science, electrical, early childhood education, agriculture, auto body, auto mechanics, diesel mechanics, carpentry, culinary and others not listed.

Vocational & Trade Education

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

Pfizer, Inc.
Corporate
Brazil, China +7 more
Up to US $50,000

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

There remains a scientific gap in understanding of the role of anti-TFPImediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Funding

  • Individual projects requesting up to $50,000 USD will be considered. Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.
  • Maximum project length is 1 year.
Rare Diseases Hematological Systems

Iowa Training and Technical Assistance Competitive Grants

Iowa Department of Justice – Office of the Attorney General, Victim Assistance Section
State/Local Government
Iowa
Unspecified amount

Office of the Attorney General

The attorney general is the State of Iowa's chief legal officer. The attorney general has general charge, supervision and direction of the state's legal business. The Office of the Attorney General provides legal advice and representation to most of the state's major departments, boards, commissions, authorities, officials and institutions. The office further represents the State of Iowa in state administrative law and Iowa District Court matters, the Iowa Court of Appeals, the Iowa Supreme Court, lower federal courts and the U.S. Supreme Court.

Training and Technical Assistance Competitive Grants

The Victim Assistance Section of the Iowa Department of Justice (“Department”) seeks applications from qualified nonprofit organizations, community-based organizations, and governmental organizations to provide trauma-informed and victim-centered training and technical assistance in Iowa. 

Purpose

The purpose of this Notice of Funding Opportunity (NOFO) is to distribute state and federal funding to eligible applicants who will support victim services organizations, agencies within the criminal justice system and other organizations with training and technical assistance to promote healing, stability, and justice for those directly impacted by violent crimes, their families, and their communities

Project Period

The first year in the grant cycle is the competitive grant year. The following two grant years are continuing (non-competitive) grant years, subject to funding availability and program performance. 

Crime & Justice Crime Victim Services Police & Law Enforcement

Art Project Grants for Organizations - Creative Abundance Special Round

Iowa Economic Development Authority
State/Local Government
Iowa
US $15,000

About Us

Your centralized resource for business and community development information and programs from the Iowa Economic Development Authority and the Iowa Finance Authority.

Art Project Grant for Organizations Program Guidelines - Creative Abundance Special Round

The Art Project Grant for Organizations program is administered by the Iowa Arts Council, which exists within the Iowa Economic Development Authority (the IEDA). Through the program, the IEDA provides financial incentives to nonprofit and tax-exempt organizations; schools; local, county, state and federal governmental agencies; and tribal councils to support a wide variety of arts-related activities.

The program is funded through an appropriation by the Iowa Legislature to the IEDA and a grant by the National Endowment for the Arts, a federal agency. Applicants must comply with federal requirements, including but not limited to 2 CFR Part 200.

Disability Care & Services Arts / Culture Access & Participation Art Education +2 more

Fair Housing Initiatives Program - Education and Outreach Initiative (362880)

US HUD: Office of Fair Housing and Equal Opportunity (FHEO)
Federal Government
American Samoa, Guam +4 more
US $175,000 - US $2,500,000
The Fair Housing Initiatives Program (FHIP), established by Congress in 1988, aims to fund organizations to combat discriminatory housing practices. The Education and Outreach Initiative (EOI) educates stakeholders about their rights under fair housing laws. Key components include the National Media Campaign, which promotes fair housing awareness nationally, and local programs that support community-based outreach. HUD oversees the process, ensuring compliance and monitoring of funded initiatives to enhance fair housing practices.
Basic Human Needs Real Estate & Housing Equitable & Affordable Housing +1 more

George and Viola Hoffman Award

American Association of Geographers
Association/Society
United States
Up to US $500

An award from the George and Viola Hoffman Fund may be made annually for student research toward a master’s thesis or doctoral dissertation on a geographical subject in Eastern Europe. Eastern Europe includes the countries of East Central and Southeast Europe from Poland south to Romania, Bulgaria, and the successor states of the former Yugoslavia. Topics may be historical or contemporary, systematic or regional, limited to a small area or comparative.

Geography

F26AS00104 State ANS Management Plan 2026

US Department of the Interior: Fish and Wildlife Service (FWS)
Federal Government
United States
US $5,000 - US $150,000
The F26AS00104 State ANS Management Plan 2026 aims to combat aquatic nuisance species through pre-proposals followed by full applications. Managed by the US Department of the Interior's Fish and Wildlife Service, this initiative requires a 25% cost-share and limits administrative costs to 5%. Applications are due by October 14, 2026, though the funding opportunity closes on December 16, 2026. The plan is crucial for maintaining biodiversity and supporting a coordinated national approach to invasive species management.
Ichthyology (Fish) Limnology Fisheries +1 more

Child Protection Compact Annual Program Statement (362907)

US Department of State: Office to Monitor and Combat Trafficking in Persons
Federal Government
American Samoa, Guam +4 more
US $5,000,000 - US $10,000,000
The Child Protection Compact Annual Program Statement invites proposals aimed at combating child trafficking through collaborative efforts between the United States and other countries. This initiative focuses on enhancing the capacity to prosecute traffickers, providing care for victims, and implementing preventive measures. Organizations interested in applying must align with the objectives of the CPC to ensure comprehensive support and effective intervention against all forms of child trafficking.
Child Welfare Services Human Trafficking

TIP Office International Programs to Combat Human Trafficking Annual Program Statement (362906)

US Department of State: Office to Monitor and Combat Trafficking in Persons
Federal Government
American Samoa, Guam +4 more
US $1,000,000 - US $10,000,000
The TIP Office of the US Department of State invites applications for projects aimed at combating human trafficking, adhering to the Trafficking Victims Protection Act. This initiative prioritizes prosecuting traffickers, protecting victims, and preventing trafficking through strategies outlined in the National Security Strategy, executive orders, and the annual Trafficking in Persons Report, while aligning with America First Foreign Policy priorities.
Human Trafficking

Enrich Iowa: Direct State Aid Grant

State Library of Iowa
State/Local Government
Iowa
Unspecified amount

About the State Library

Mission:

The State Library of Iowa strengthens Iowa library services and information access for Iowans.

Enrich Iowa

About Enrich Iowa

The State Library annually administers funding appropriated by the Iowa Legislature to libraries in Iowa. Enrich Iowa consists of three programs to aid libraries in offering improved service to Iowans:

More About Direct State Aid

Direct State Aid funding is distributed to participating public libraries through a formula that calculates:

  • A base amount dependent on Tier Level met, as set by the Accreditation & Standards program.
  • The per capita amount based on the population of the city and level of compliance with quality measures.
  • Three percent of the amount of funding received by the library in the previous fiscal year for service to rural residents and contracting communities.
Library Services

DOW Combat Readiness – Medical Research Program Translational Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,450,000
The DOW Combat Readiness – Medical Research Program's FY26 Translational Research Award supports innovative research aimed at improving trauma care outcomes. This program emphasizes hypothesis-driven studies that can transition promising technologies into practical solutions for enhancing casualty survivability. Applicants must provide preliminary data and utilize validated animal models, with a focus on projects that meet a minimum technology readiness level of 4, ensuring a mature translational research effort.
Crisis Intervention Post-Traumatic Stress Disorder

Improved Drug Susceptibility Testing (DST) for Mycobacteria

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.
Infectious & Parasitic Diseases Tuberculosis Drug-Resistant Bacteria

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