Best Des Moines Grants for Nonprofits in Iowa

The Elevance Health Foundation's Food as Medicine Grant aims to enhance access to nutritious foods and improve health outcomes for individuals facing diet-related conditions. This initiative invites qualified nonprofits to submit proposals focused on scalable solutions that address food insecurity and promote health equity. The foundation prioritizes programs that demonstrate measurable outcomes and support whole-person health, particularly for populations at high social risk. Grants will be awarded for a term of 1-3 years, with funding based on program needs.

Bob's Discount Furniture Charitable Foundation supports non-profit organizations with resources rather than individual sponsorships. They require requests to be submitted on the letterhead of a qualified 501(c)(3) organization. This ensures that assistance reaches those in need through established channels. Interested parties should provide specific details regarding their requests to facilitate the application process. With a commitment to fairness, Bob's Cares aims to effectively support community initiatives across the country.

The CATCH Grant, offered by USA Football, provides essential support to organizations facing critical challenges such as natural disasters or theft. This program aims to enhance the athlete experience by assisting with unexpected hardships affecting operations. Eligible organizations enrolled with USA Football can apply for varying award amounts based on their specific circumstances. For more information, refer to the FAQs available on the USA Football website.

The Transformative Organizing Grants, funded by the Arch Community Fund, aim to bolster grassroots movements advocating for systemic change. These grants, ranging from $15,000 to $25,000, prioritize organizations with 501(c)(3) status and an annual budget under $1 million. The focus is on empowering community leadership through anti-capitalist solutions, promoting intersectionality, and addressing immediate needs while fostering long-term structural change. Eligible groups are encouraged to apply for support in their transformative organizing efforts.

The Strengthening Families and Communities Grant by Telligen Community Initiative focuses on enhancing the resilience of youth and families through community-based funding. This initiative is transitioning to two-year funding periods, with applications due in March and October for different states. The grant aims to address social determinants of health, providing targeted support based on extensive applicant feedback. The program emphasizes a narrowed applicant pool to ensure more consistent funding for impactful projects.

The National Center for Construction Safety and Health Research and Translation (U54) aims to enhance worker safety in the construction industry through innovative research and intervention strategies. By fostering partnerships and focusing on evidence-based solutions, the Center will address critical safety and health challenges faced by construction workers. The initiative aligns with NIOSH's strategic objectives, promoting collaboration among academic institutions and organizations to improve health outcomes and reduce the occupational health burden in this vital sector.

The Music Man Foundation invites eligible organizations to apply for Advocacy and Research Grants aimed at supporting systemic change in the arts sector. Organizations must demonstrate their impact on music-related systems, showcase their priorities in the field, and outline their achievements. Grants will assist with research, advocacy training, and cross-sector initiatives to enhance community vitality and promote sustainable solutions, reflecting the Foundation's commitment to fostering positive arts engagement.

The National Meredith Willson Awards provide multi-year operating support to organizations using music for systemic change. The Music Man Foundation will award grants of $50,000 to $500,000 to 5-10 selected organizations in 2026, focusing on their impact through music. Eligible organizations must have 501(c)(3) status, a history of music programming, and a commitment to systemic change. Applications will be evaluated on leadership, organizational capacity, and alignment with grant criteria.

The NDEP STEM Open NFO invites innovative proposals for research and implementation of effective STEM education and outreach programs. This continuously open announcement from the Department of Defense encourages submissions that align with key initiatives, including support for community colleges and strategic partnerships. As funding becomes available, amendments detailing specific topics and submission guidelines will be released. Applicants must submit white papers to express interest in full applications for potential funding consideration.

The National Book Fund (NBF) offers grants to support adult education and literacy programs across the U.S. by providing New Readers Press materials. Grants typically range from $500 to $2,000, with applications considered for higher amounts if justified. Eligible applicants must have a defined project and use materials directly with learners. Priority is given to nonprofit organizations providing free literacy instruction. Note that individuals and lending libraries are not eligible for funding.

The Growing Research Access for Nationally Transformative Equity and Diversity program, funded by the National Science Foundation, aims to enhance the research enterprise by addressing structural barriers and promoting inclusivity. By focusing on administrative support and innovative strategies, the initiative seeks to empower diverse organizations to participate in research. Proposals should target institution-wide impacts and scalable models that strengthen human capital and research practices, fostering a more equitable and competitive research landscape.

The It Gets Better Project is offering 50 grants of up to $10,000 each to public and charter schools across the U.S. to enhance inclusivity for LGBTQ+ youth. Schools can propose projects such as enhancing library resources, artistic installations, or establishing support groups. The initiative aims to empower LGBTQ+ students and foster a supportive environment, ensuring that every school can participate in uplifting their communities and promoting equality.

The FY 2025 EDA Public Works and Economic Adjustment Assistance Programs aim to enhance economic growth and resilience in distressed communities. EDA invites ongoing applications for funding, focusing on innovative approaches that leverage regional strengths. The updated NOFO emphasizes timely reviews and outlines submission procedures for core programs under the Public Works and Economic Development Act. Grantees are encouraged to develop unique initiatives that foster lasting economic prosperity.

The Richard King Mellon Foundation invites innovative proposals that align with their 2021-2030 Strategic Plan, aiming to invest over $1.2 billion to enhance opportunities in southwestern Pennsylvania. Their funding focuses on conservation, economic development, economic mobility, health and well-being, organizational effectiveness, and social-impact investments. The General Application offers flexibility without deadlines, allowing for a variety of support types, including project-specific and general operating funding, aimed at enriching community vitality and environmental stewardship.

The Felix E. Martin Jr. Foundation Community Leadership Fund provides essential support for leadership development in Muhlenberg County, KY. It aims to empower individuals and groups seeking innovative solutions to local challenges. Eligible applicants include those pursuing personal leadership growth or researching effective community strategies. The fund underscores inclusivity, welcoming diverse applicants without discrimination. This initiative fosters a vibrant community by equipping leaders with the resources needed to effect positive change.

The TFish Fund Grant aims to alleviate poverty in East Asia by empowering small but impactful NGOs to achieve sustainability and transparency. Founded in 2011, the Transparent Fish Fund partners with select organizations that focus on poverty alleviation. By providing financial aid, capacity building, and promoting accountability, the fund bridges the gap between Western donors and local NGOs, fostering a philanthropic spirit while addressing the complex social issues faced in the region.

This funding opportunity aims to support Early Stage Investigators (ESIs) in conducting preclinical HIV/AIDS research using Nonhuman Primate (NHP) models. Eligible applicants must have at least two years of postdoctoral experience and be within ten years of their terminal degree. The initiative aligns with the NIH Strategic Plan for HIV and HIV-Related Research, targeting the reduction of HIV incidence, development of therapies, and advancement in research areas related to HIV.

The Research Experiences for Undergraduates (REU) program, funded by the National Science Foundation (NSF), promotes active research participation among undergraduate students across various research areas. It supports two mechanisms: REU Sites, which engage multiple students in ongoing research, and REU Supplements, which enhance existing NSF-funded projects. Participants must be U.S. citizens, nationals, or permanent residents, and each REU opportunity has its unique application process.

Rails-to-Trails Conservancy (RTC) Trail Grants

RTC’s Trail Grants are building strong foundations in communities for equitable trail network development and activation—investing in transformative projects and programs that create more access to trails for more people across the country.  

Our grants support organizations at all levels—from local and national nonprofits to public agencies—with a focus on community-based leadership, engagement and long-term impact.  

Since 2008, RTC has provided over $3.7 million in grant funding to more than 280 organizations seeking to create, connect and maintain the nation’s trails, building vibrant trail networks that connect neighborhoods and regions, and make it possible for America to walk, bike and be active outside.

The Historical Resource Development Program Annual Grant supports the preservation, conservation, and education of Iowa's historical resources. Established by the Code of Iowa, it offers funding to nonprofit corporations, governmental units, and individuals, with a focus on projects that enhance economic and cultural development. While grants can reach $100,000, applicants are encouraged to request up to $50,000. Key priorities include projects involving trained professionals and documentary collections with significant historical value.

The Trail Accelerator Grants aim to enhance mountain bike trail communities by providing essential planning and design services. With funding between $10,000 to $30,000, these grants support local organizations in creating sustainable trail systems. The initiative encourages projects that increase access and promote community engagement, particularly focusing on diversity and inclusion. Applicants must demonstrate the capacity to match funds, ensuring collaborative efforts to improve trail networks and experiences for all riders.

The Mathematical Sciences Postdoctoral Research Fellowships (MSPRF) aim to support emerging leaders in mathematics and statistics. These fellowships enhance participants' research environments, ensuring significant scientific development. Awardees can choose between a Research Fellowship or a Research Instructorship, with funding available for research across various mathematical and statistical disciplines. Proposals are submitted directly to the NSF, and fellows must affiliate with eligible institutions or organizations.

The Mathematical Sciences Research Institutes, supported by the National Science Foundation, serve as critical national resources aimed at advancing research in mathematics and statistics. These institutes facilitate the discovery and dissemination of knowledge while enhancing connections with related fields. Their activities attract top mathematical minds to tackle pressing problems and engage a diverse array of U.S.-based researchers, ultimately bolstering the impact of mathematical sciences across various disciplines.

The Founders Project Fulfillment Grant, offered by the Children's Theatre Foundation of America (CTFA), is dedicated to supporting 501(c)(3) IRS-certified theatres with a strong commitment to artistic excellence for young audiences. Eligible organizations must have a minimum operating budget of $1,000,000 and a proven track record of diversity in leadership, making this grant a vital resource for fostering inclusive theatre experiences for children and families.

The Ash Grove Charitable Foundation Grant supports public charities with 501(c)(3) status, focusing on capital projects that enhance community life in states where Ash Grove operates. With a commitment to environmental sustainability, education, and human services, the Foundation prioritizes funding for renovation and construction projects. Grants typically reach up to $25,000, aiming to foster better living standards and support local initiatives that are vital for community growth and resilience.

Bell's Brewery Small Grassroots Grants support projects focusing on water stewardship across the Great Lakes watershed. With grant amounts ranging from $500 to $5,000, eligible organizations can apply for funding to improve ecosystem health, enhance public health through better water resource management, and promote resilience against climate-related water risks. This initiative highlights Bell's commitment to environmental stewardship and community support in all 50 states and DC.