Best Large Grants for Nonprofit Organizations in District of Columbia

Mission

The Fish Family Foundation of Maine is a faith based charitable organization located in Bangor, Maine. Founded in 2007, our mission is to provide resources for many initiatives including, but not limited to, missions, education scholarships, ministries, medical research, and employment creation. The Fish Family Foundation of Maine is primarily funded by the family. However, contributions from like minded individuals and organizations is appreciated. The Fish Family Foundation of Maine has a balanced strategy of making funds available for immediate needs, while also investing to build a perpetual earning endowment ensuring the Foundation's successful future.

Missions:

We support needs of missionary organizations including sponsorships for young people who wish to attend youth group sponsored mission trips. We ordinarily make one time contributions but on occasion have made up to a three year commitment. 

Education/Scholarships:

The Foundation makes scholarships available to Colleges, Universities, and other Schools for student enrollment and expenses. We also consider new construction, existing renovation, equipment, and support material contributions.

Independent Churches and Ministries:

We accept a wide variety of requests, including, but not limited to: materials, equipment, new construction, renovations, programs, and services. 

Medical Research:

We support medical research opportunities close to our hearts and organizations that our family and friends have experienced. 

Job Creation:

We Support organizations that fund entrepreneurs in impoverished areas to start small businesses providing services and employment to the community.

Requests are considered by the trustees the first week of each month. Foundation payments are made by paper check in US dollars and are reported to the appropriate tax agencies. While we certainly wish that we could contribute to all the applications that meet our funding criteria, there are times when when available funding is limited and we are not able to contribute to some very worthy causes. If we are not in a position to help in the timeline requested, we will keep the information on file for possible consideration in the future. 

Patagonia supports environmental organisations with bold, direct-action agendas and a commitment to long-term change.

We support innovative work that addresses the root causes of the environmental crisis and seeks to protect both the environment and affected communities. We focus on places where we’ve built connections through outdoor recreation and through our network of retail stores, nationally and internationally.

We believe local battles to protect a specific stand of forest, a stretch of river, an indigenous wild species or a community from a polluting refinery build public support and confront larger, more complex issues like climate change, biodiversity loss and environmental justice.

We encourage work that brings underrepresented communities to the forefront of the environmental movement and defends communities whose health and livelihoods are threatened by environmental exploitation.

We support multipronged campaigns that push for greater environmental protections and force the government to abide by its own laws.

We fund work that:

• builds an equitable, inclusive and diverse environmental movement
• confronts systemic bias, discrimination and injustice in environmental policy or outdoor spaces
• is action-oriented
• focuses on root causes
• has a clear strategy
• identifies specific goals and objectives that can be effectively measured to evaluate success
• builds public involvement and civic engagement

Patagonia believes that the most direct path to real change is through building grassroots momentum.

Our funding focuses on organisations that have or can create a strong base of support. Because we’re a privately held company, we have the freedom to fund risk-taking, off-the-beaten-track groups, and that’s where we believe our small grants are most effective.

The Zonta Club of Greater Sandusky High School STEM Scholarship Fund provides financial support to female high school seniors from Erie, Huron, or Ottawa County, Ohio, who plan to pursue a degree in STEM or medical fields at accredited institutions. Established by the Zonta Club, this scholarship aims to empower young women to contribute positively to their communities by facilitating access to higher education opportunities. Since its inception, it has fostered academic growth and leadership among recipients.

The Greenpoint Foundation Grant aims to enhance community life by supporting organizations that focus on agriculture, food security, education, and community enhancement. Established in 2022, the Foundation accepts grant applications year-round for both general operating budgets and specific projects. Priority is given to 501(c)(3) organizations and local government entities, while faith-based programs are considered on a case-by-case basis. Grant recipients must submit impact reports to ensure continued support.

The Council of Independent Colleges

Founded in 1956, the Council of Independent Colleges (CIC) is an association of nonprofit independent colleges and universities, state-based councils, and higher education affiliates that works to support college and university leadership, advance institutional excellence, and enhance public understanding of independent higher education’s contributions to society.

CIC is the major national organization that focuses on providing services to leaders of independent colleges and universities and state-based councils. CIC offers conferences, seminars, publications, and other programs and services that help institutions improve educational quality, administrative and financial performance, student outcomes, and institutional visibility.

NetVUE Vocation across the Academy Grants

​One major purpose of an undergraduate education in the liberal arts is to help students shape a philosophy of life. At the same time, undergraduates today are increasingly preoccupied with postgraduate employment. The purpose of this grant program is to help colleges and universities develop more effective ways to strengthen the link between these two purposes of undergraduate education. It is designed to support institutions in their efforts to expand vocational exploration and discernment programs across the curriculum and co-curricular programs, with the following goals:

• to help students develop more effective links between developing a philosophy of life and preparing for a career;
• to include more faculty and students in the work of vocational exploration and discernment; and, in some cases,
• to build connections with community partners, such as local businesses, nonprofits, and other community organizations.

The Harry Sudakoff Foundation Grant supports qualified charities in Sarasota, Florida, focusing on arts, community, education for youth, environment, human services, and science. Established by builder Harry Sudakoff, the foundation prioritizes organizations with a history of support. Grants are restricted to 501(c)(3) entities, excluding individuals and certain funding types like endowments and operating expenses. A commitment to impactful contributions is central to the foundation's mission.

Syndax Pharmaceuticals, Inc.

At Syndax, we are determined to realize a future in which people with cancer live longer and better than ever before. We believe that it takes a community to build a great medicine, and that is why we are working to set the new standard for developing medicines in the field of oncology – one that revolves around collaboration, shared learning, and excellence.

Syndax’s mission is to obtain regulatory approval and commercialize drugs that extend and improve the lives of cancer patients by drawing on the newest scientific research and advances, collaborating with determined problem solvers, and identifying value in overlooked aspects of science.

Educational Funding

At Syndax, we are committed to the goal of supporting objective, balanced and scientifically rigorous education that furthers improvements in science, medicine, and patient care. We accomplish this goal, in part, by providing grants for independent medical education (IME) programs. These can include live, online, and/or enduring programs that educate healthcare providers (HCPs), patients, or caregivers. Programs that are funded via Syndax medical education grants must be primarily dedicated, in both effort and time, to medical, health or scientific topics that are objective, balanced, unbiased, and scientifically rigorous. Medical education grants must never be made with the intent to directly or indirectly reward, influence or encourage the recipient to prescribe, purchase, sell or arrange for any Syndax product.

Danny Did Foundation

The Danny Did Foundation is a not-for-profit corporation organized in the state of Illinois and recognized by the Internal Revenue Service as a 501©(3) tax-exempt organization. 

Founded by Chicagoans Mike and Mariann Stanton in January 2010 after the death of their four-year-old son Danny, the Danny Did Foundation works toward its mission to prevent deaths caused by seizures with these main goals in mind: advancing public awareness of Sudden Unexpected Death in Epilepsy (SUDEP), enhancing SUDEP education and disclosure between medical professionals and families afflicted by seizures, and the mainstreaming of seizure detection and prediction devices that may assist in preventing seizure-related deaths.

Danny Did Foundation Hardship Grant

The Danny Did Foundation (“Foundation”) strives to assist individuals and families living with seizures. With an approved Request for Funding, the Foundation will provide monetary funding to the Grantee so they may gain access to a particular device or technology (“Device”) that the Grantee, in collaboration with the Grantee’s medical providers and professionals, independently deem appropriate. This money shall be defined as “Funds” and the spending of any Funds shall be at the sole discretion of the Grantee. The Foundation does not direct, limit, participate, or manage the decision-making or purchase of any specific Device.

While no Device has been proven to prevent epilepsy-related mortality (including SUDEP), the Danny Did Foundation is devoted to seeking out resources that may assist families living with epilepsy.

Hardship Grant: I am unable to make a purchase for the epilepsy related resource I seek therefore I am requesting a hardship grant. If I am approved for funding, I agree to provide a receipt for the resource I purchase to the Danny Did Foundation within 14 days of receiving the grant check, or I will return the funds to the Danny Did Foundation. 

Danny Did Foundation

The Danny Did Foundation is a not-for-profit corporation organized in the state of Illinois and recognized by the Internal Revenue Service as a 501©(3) tax-exempt organization. 

Founded by Chicagoans Mike and Mariann Stanton in January 2010 after the death of their four-year-old son Danny, the Danny Did Foundation works toward its mission to prevent deaths caused by seizures with these main goals in mind: advancing public awareness of Sudden Unexpected Death in Epilepsy (SUDEP), enhancing SUDEP education and disclosure between medical professionals and families afflicted by seizures, and the mainstreaming of seizure detection and prediction devices that may assist in preventing seizure-related deaths.

Danny Did Foundation Reimbursement Grant

The Danny Did Foundation (“Foundation”) strives to assist individuals and families living with seizures. With an approved Request for Funding, the Foundation will provide monetary funding to the Grantee so they may gain access to a particular device or technology (“Device”) that the Grantee, in collaboration with the Grantee’s medical providers and professionals, independently deem appropriate. This money shall be defined as “Funds” and the spending of any Funds shall be at the sole discretion of the Grantee. The Foundation does not direct, limit, participate, or manage the decision-making or purchase of any specific Device.

While no Device has been proven to prevent epilepsy-related mortality (including SUDEP), the Danny Did Foundation is devoted to seeking out resources that may assist families living with epilepsy.

Reimbursement Grant: Danny Did will consider partial reimbursement for device purchases made in the last 30 days. I have already purchased the epilepsy device. I am seeking reimbursement and will provide receipt of purchase to the Danny Did Foundation to be considered for funding.

The Glick Education Award, offered by the Central Indiana Community Foundation, supports educational opportunities for dependents of Gene B. Glick Company employees. Eligible applicants include high school seniors and current post-secondary students. Selection criteria focus on academic achievement, leadership, community involvement, work experience, and financial need. Awards cover tuition, fees, and other educational expenses at accredited institutions. This initiative aims to foster educational attainment within the community, promoting access regardless of race or identity.

The Robert L. Johnson Memorial Research Grant, offered by the Midwest Aquatic Plant Management Society, supports graduate students in aquatic plant management with grants of up to $10,000. This initiative promotes research that advances the management of aquatic ecosystems and fosters educational opportunities. Recipients are required to present their findings at the annual conference, contributing to the society's mission of sustainable aquatic resource management and ecological preservation.

The BioMarin Medical Education Grant offers funding for educational activities aimed at enhancing the knowledge and skills of healthcare professionals. Eligible applicants include accredited providers, medical associations, and patient advocacy groups. The grant focuses on supporting initiatives related to rare diseases, ensuring timely access to treatments and education. Applications are accepted year-round, but a minimum of 60 days is required for review prior to events. This commitment underscores BioMarin's dedication to improving patient care and advancing medical knowledge.

The LEGO Foundation Fellowship

Advancing the science and practice of supporting children to thrive

The LEGO Foundation Fellowship is a global initiative supporting researchers working to deepen our understanding of how children thrive. Spanning disciplines from education and psychology to public health, data science, and humanitarian studies, the fellowship brings together early- and mid-career scholars whose work has the potential to generate evidence that matters for children’s lives.

Fellows receive three years of flexible support to pursue rigorous, practically relevant research, and join a cohort of peers working across the fellowship’s themes. In addition to funding research, the program fosters a community of scholars engaged in meaningful exchange with one another and with research, policy, and practice audiences.

The LEGO Foundation Fellowship is developed in partnership with the LEGO Foundation, and administered by SSRC as part of its commitment to supporting scholars whose work bridges research and real-world impact.

Research themes

The LEGO Foundation Fellowship welcomes research proposals that advance understanding of children’s thriving through one of the following three themes: the youngest children in crisis and conflict settings; inclusion and wellbeing of neurodivergent children; and children’s learning and development in an AI-enabled world. Applicants may explore the role of play where it is relevant to the research question. The consideration of play is optional and not a condition of eligibility.

Gropper Clement Legacy Scholarship

To provide financial support to graduates of Huron, James Valley Christian, Kadoka and Miller High Schools.

The Hypercholesterolemia Grant by the Patient Advocate Foundation offers financial assistance to individuals diagnosed with hypercholesterolemia, helping cover out-of-pocket healthcare costs such as medication copays and insurance premiums. This nonprofit aims to improve patient access to necessary care while supporting over 3.8 million patients since its inception. Eligible applicants must have health insurance and meet specific income requirements to receive assistance in managing their healthcare expenses effectively.

The Hyperkalemia Grant, provided by the Patient Advocate Foundation, offers crucial financial assistance to patients struggling with hyperkalemia. This grant covers out-of-pocket healthcare costs, including medication copays and health insurance premiums. Eligible applicants must have a confirmed diagnosis and meet specific income and residency requirements. Since its inception, the foundation has supported millions of patients, ensuring they can access the necessary treatment and resources for their health needs.

The Native American/Native Hawaiian Museum Services (NANH) program, funded by the Institute of Museum and Library Services (IMLS), aims to support Native American Tribes, Alaska Native Villages, and organizations serving Native Hawaiians. It focuses on preserving heritage and culture through educational services, workforce development, capacity building, community engagement, and effective collections stewardship. This initiative is crucial for sustaining the rich cultural heritage of Native communities.

The US Department of Health & Human Services, through the FDA, is funding clinical trials targeting rare neurodegenerative diseases. This initiative aims to enhance treatment options by evaluating the efficacy and safety of new products for both children and adults. By fostering innovative and collaborative trial designs, the FDA seeks to accelerate the approval of new therapies, ultimately benefiting patients with rare conditions and advancing drug development in this critical area.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Help with healthcare costs for Paroxysmal Nocturnal Hemoglobinuria (PNH)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Paroxysmal Nocturnal Hemoglobinuria (PNH), also known as Marchiafava– Micheli syndrome, is a rare disease that is characterized by impaired bone marrow function and destruction of red blood cells. PNH is a rare disease that affects the circulatory system.

The Periodic Paralysis Grant, offered by the Patient Advocate Foundation, assists individuals diagnosed with periodic paralysis in managing out-of-pocket healthcare costs. Eligible applicants must be in treatment or planning to begin treatment for this rare muscle disease. The fund covers various expenses, including medication copays and insurance premiums, ensuring that patients can afford essential care. With a mission to empower and support patients, this grant plays a crucial role in navigating healthcare challenges.

The AISES RISE Scholarship offers $2,000 annually to support Indigenous students pursuing careers in STEM, particularly in the casino gaming industry. This initiative, powered by Aristocrat Gaming, aims to empower Indigenous talent through exposure, resources, and programming. Eligible applicants must be full-time students and current AISES members, demonstrating a commitment to their education and community. The scholarship seeks to enhance diversity in STEM fields by providing critical financial support to deserving students.

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 300 funds and approximately $80 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Barbara Miller Meeker Art Scholarship

Use the chart below to see which scholarships are the best fit for you! You must complete the Legacy Universal Application to apply.

Scholarship eligibility requires students to attend an accredited 2 or 4 year public or private institution of higher learning. All scholarships are for full-time students, unless otherwise noted. Renewable awards are for 4 years of undergraduate study and cannot be used for post graduate coursework; all awards are paid directly to the school or may be used for book reimbursement.

About

Created by the community for the good of the community, the GLCCF is here to turn problems into opportunities through strategic grant making and initiatives created to address our region’s most pressing needs. We work with you to identify your charitable goals, and we ensure that they are carried out efficiently.

Work with us to make the kind of impact you want to see in your community. Let us take on the financial complexities and paperwork, while you focus on the important things like fostering good works throughout our community.

When you give to the Greater Lake City Community Foundation, you are making an investment that will benefit the community, now and in the future.

GLLCF Nursing Scholarship

To award annually a scholarship to a qualified applicant who intends to further his/her education toward a degree in nursing.

The Rural Communities Opioid Response Program - Evaluation aims to assess the effectiveness of behavioral health strategies in rural settings. By developing evaluation tools and resources, this initiative seeks to empower local communities in their health initiatives, ensuring that future programs are informed by comprehensive evaluations. Funded by the Health Resources and Services Administration, the program highlights the importance of tailored approaches to address opioid-related challenges in rural areas.

The National Cancer Institute (NCI) is seeking applications for studies that explore how bariatric surgery influences cancer risk, emphasizing the need for innovative research in this area. This funding opportunity encourages the participation of researchers who focus on the long-term impacts of bariatric surgery beyond weight loss and diabetes, addressing critical gaps in understanding the disease mechanisms involved. Key deadlines for application submissions span from February 2025 to October 2027.

The Native Forward CPA Examination Funding provides crucial financial assistance to American Indians and Alaska Natives for covering the costs associated with the CPA examination. This initiative empowers students and professionals to pursue CPA licensure by assisting with application, registration, and exam fees. Eligible applicants can receive support for one section of the exam at a time, ensuring access to essential resources for advancing their careers and contributing positively to their communities.

The TIRBEE funding opportunity supports federally-recognized Tribes and Tribal Entities in establishing or enhancing Institutional Review Boards. This initiative aims to strengthen the capacity for biomedical research involving human participants within these communities by improving review and oversight capabilities. Eligible organizations are invited to apply, with applications subject to NIH's standard peer-review process to ensure only the most meritorious proposals are considered.