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Best Large Grants for Nonprofit Organizations in District of Columbia

Find the perfect Large Grants for Nonprofit Organizations in District of Columbia on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in District of Columbia in the United States.

9,000+

Available grants

$2.61B

Total funding

$5K

Median grant

9,000+ grants
$2.61B total
$5K median

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9,308 Results based on applied filters

DGF Bridge Grants

Dramatists Guild Foundation
Private
United States
US $500
The DGF Bridge Grants provide essential financial support of $500 to professional dramatists facing hardships. This one-time award helps cover non-emergency daily expenses such as housing, utilities, and healthcare. Eligible applicants must be U.S.-based dramatists with limited financial resources and have not previously received a DGF Bridge Grant. By nurturing today's creators, DGF ensures the continuation of impactful storytelling in the theater community.
Theater Basic Human Needs Mental Health & Psychiatric Diseases +1 more

RADM (ret.) Jeffrey A. & Linda J. Cook Scholarship

United Negro College Fund Inc
Private
United States
Up to US $4,250

Our Impact

UNCF was founded in 1944 to help more African American students attend and graduate from college.

Since then, we've helped to more than double the number of minorities attending college.

For Students

UNCF is more than just scholarships. We’re the nation’s leading minority education organization and our goal is to help you get to and through college.

Our support takes many different forms. From merit scholarships to financial assistance, on-campus assistance to professional development, emergency financial aid to community support, UNCF is committed to getting more students like you to and through college.

2026-2027 The RADM (ret.) Jeffrey A. & Linda J. Cook Scholarship

The RADM (ret.) Jeffrey A. & Linda J. Cook Scholarship is a need-based, recurring scholarship for active-duty, retired U.S. military veterans, or their dependents who are enrolled full time and pursuing undergraduate STEM degrees at an accredited HBCU. Recipients will receive a renewable award of up to $4,250 to support them in obtaining their undergraduate degree.

This scholarship is in honor of CPO Arthur A. Cook and Capt. Delbert E. Colwell, the fathers of the Grantors who served honorably during WWII.

Education - Higher Education Military & Veterans Services Educational Access & Equity +2 more

Louis Stokes Alliances for Minority Participation (LSAMP) Bridge to Doctorate Scholars Program

Montana State University
State/Local Government
United States
US $88,000
The Louis Stokes Alliances for Minority Participation (LSAMP) Bridge to Doctorate Scholars Program, funded by the National Science Foundation, aims to recruit and retain minority graduate students in STEM fields. This program offers significant benefits, including a $32,000 annual stipend and $12,000 educational allowance for two years, fostering a supportive community through monthly dinners for Indigenous graduate students. Eligible applicants must be U.S. citizens, identify as American Indian or Alaska Native, and have participated in an LSAMP program.
Education - Higher Education Academic Success & Enrichment Academic Scholarship Programs +3 more

Leonard Litz Foundation-TransPLUS Resource Grants

Leonard Litz Foundation
Private
United States
Unspecified amount
The Leonard Litz LGBTQ+ Foundation, via its TransPLUS Resource Center, supports transgender, gender-nonconforming, non-binary, and intersex individuals. By providing grants and resources, the Foundation aims to address urgent needs in healthcare, housing, and legal services while fostering community connections. They build peer-support networks, publish updates, and support initiatives to empower TGNCNBI individuals and their allies, ensuring that marginalized voices are heard and uplifted.
Sexuality & LGBTQIA+ Rights LGBTQIA+ Services Intersex & Transgender Rights

Native Forward Direct Scholarship

Native Forward Scholars Fund
Association/Society
United States
Unspecified amount
The Native Forward Direct Scholarship supports American Indian and Alaska Native students by providing mid-year funding opportunities to alleviate educational costs. With over 50 years of experience, Native Forward has empowered more than 22,000 students from diverse backgrounds. This scholarship recognizes the limited access these students face in higher education and aims to enhance their academic journeys while fostering community engagement and mentorship through a strong alumni network.
Education - Higher Education Academic Success & Enrichment Native American Services +2 more

Native Forward CPA Examination Funding

Native Forward Scholars Fund
Association/Society
United States
Unspecified amount
The Native Forward CPA Examination Funding provides crucial financial assistance to American Indians and Alaska Natives for covering the costs associated with the CPA examination. This initiative empowers students and professionals to pursue CPA licensure by assisting with application, registration, and exam fees. Eligible applicants can receive support for one section of the exam at a time, ensuring access to essential resources for advancing their careers and contributing positively to their communities.
Education - Higher Education Academic Success & Enrichment Native American Services +2 more

Native Forward Community Impact Research Funding

Native Forward Scholars Fund
Association/Society
United States
Unspecified amount
The Native Forward Community Impact Research Funding supports doctoral candidates conducting research that addresses issues affecting Indian Country. This initiative provides essential financial assistance for data collection, analysis, and research travel, ensuring that Native perspectives are included in academic discourse. By fostering the next generation of Native leaders, this funding aims to empower scholars and enhance community impact through education and advocacy, ultimately preserving and enriching Native cultures.
Education - Higher Education Academic Success & Enrichment Native American Services +2 more

Ben & Rose Schwabenbauer Educational Scholarship

Cattaraugus Region Community Foundation
Private
United States
Unspecified amount

Ben & Rose Schwabenbauer Educational Scholarship

Established by Ben and Rose Schwabenbauer, former long-time teachers in the Olean City School District, this fund awards scholarships for graduating seniors from Olean High School, Otto-Eldred High School, Portville Central School or Bradford Area High School who will be attending a 4-year college with a preference for students majoring in education, particularly elementary education; criminal justice or a law enforcement-related field; or healthcare-related fields of study. 

Education - Higher Education Crime & Justice Police & Law Enforcement +2 more

Alkermes Pathways Research Awards

Alkermes
Corporate
United States
Up to US $100,000
The Alkermes Pathways Research Awards program aims to foster research in neuroscience, specifically targeting schizophrenia and bipolar disorder. With grants up to $100,000, it supports early-career investigators exploring critical areas, including sleep and circadian disturbances related to these conditions. This initiative addresses the urgent need for innovative solutions in mental health research, empowering the next generation of scientists to make impactful contributions in understanding and treating these complex disorders.
Schizophrenia Mental Health & Psychiatric Diseases Sleep

Clark and Ruby Baker Foundation Grant

Clark and Ruby Baker Foundation
Private
United States
Unspecified amount
The Clark and Ruby Baker Foundation Grant aims to support charitable organizations that align with the philanthropic mission of the Baker family, focusing on Methodist-affiliated educational institutions, aid for disadvantaged children, and assistance for the sick in Georgia. The Foundation considers funding for construction projects of educational and medical facilities, ensuring that grants are awarded to meet specific community needs and promote long-term benefits.
Education - Higher Education Christianity Senior Services +3 more

Princess Grace Awards

Princess Grace Foundation
Private
United States
US $15,000
The Princess Grace Awards support early career artists in theater, dance, and film with unrestricted cash grants of $15,000. Open to U.S.-based artists, the awards recognize both creative generators and performance-based creatives. Nominations are required from non-profit organizations or previous award winners, ensuring a robust evaluation of artistic merit. With a focus on nurturing talent, the Princess Grace Foundation honors the legacy of Princess Grace of Monaco by fostering the next generation of artists.
Theater Dance Film +1 more

Stephany June Bryan: Bold Spirit of Achievement Scholarship

Hogg Foundation for Mental Health
State/Local Government
United States
US $5,000

Hogg Foundation for Mental Health

The Hogg Foundation for Mental Health was established in 1940 at The University of Texas at Austin by the children of Texas Governor James Hogg. For over a quarter of a century, the Hogg Foundation was guided by the passion and insight of the Governor’s daughter, Miss Ima Hogg, who actively promoted the foundation and encouraged its staff to pursue a bold, new vision. Today the Hogg Foundation is based at The University of Texas at Austin Steve Hicks School of Social Work and is funded through an endowment created by gifts from the Hogg family and managed by The University of Texas/Texas A&M Investment Management Company.

The Hogg Foundation is inspired by Ima Hogg’s vision for a Texas that supports and promotes mental health, resilience, and well-being. Miss Ima was ahead of her time in believing that mental health was just as important as physical health. She believed all people should have access to community-based resources to support mental well-being and live fulfilling lives, and she championed supports in everyday environments like schools, workplaces, places of worship, and homes.

Stephany June Bryan: Bold Spirit of Achievement Scholarship

The Hogg Foundation for Mental Health is offering ten $5,000 scholarships in honor of Stephany June Bryan to individuals facing personal and financial barriers to achieving their educational or career goals due to the impact of living with a mental health challenge and/or supporting a loved one with a mental health challenge.

You do not need to be enrolled in a program at the time you submit your application. However, you will need to provide enrollment verification and/or a certificate of completion when/if it is awarded.

Mental Health & Psychiatric Diseases Education - Higher Education Vocational & Trade Education +2 more

Indian Housing Block Grant Competitive Program (IHBG-COMP) for FY 2026

US HUD: Office of Public and Indian Housing (PIH)
Federal Government
United States
US $500,000 - US $7,500,000
The Indian Housing Block Grant Competitive Program (IHBG-COMP) for FY 2026 offers competitive grants to eligible recipients under NAHASDA. This program aims to support affordable housing initiatives benefiting low-income Tribal families, enhancing their living conditions and community well-being. Funded by the US HUD's Office of Public and Indian Housing, the IHBG-COMP encourages the development of sustainable housing solutions within Native American communities.
Minority Services Equitable & Affordable Housing Native American Services

American Fundraising Foundation Inc Request Support

American Fundraising Foundation Inc
Private
United States
Unspecified amount

Mission

To empower worthy nonprofits by providing critically needed, unrestricted funding that helps them fulfill their missions with confidence and sustainability.

How We Serve Nonprofits

AmFund partners with nearly 800 organizations annually—supporting causes related to health, education, the arts, human services, animal welfare, and more. We’re known for our:

  • Signature silent and live auctions featuring once-in-a-lifetime travel experiences.
  • National reach with personalized service at events in all 50 states.
  • Comprehensive marketing toolkits, onsite staff support, and beautifully displayed materials
  • No-cost platform development for virtual and hybrid fundraising
  • In-house travel specialists who provide custom planning, extensions, insurance, and 24/7 emergency support.
  • Ongoing educational resources, grants, and consulting support for nonprofit development.

Request Support

Our model is built on relationship, trust, and results. Every trip sold, every service provided, and every donor interaction is designed to maximize your fundraising impact—without adding burden to your team.

Health Care Access & Delivery Health Disparities & Social Determinants of Health Educational Access & Equity +3 more

St. Ignace Area Community Foundation: CTE Technical Scholarship

St. Ignace Area Community Foundation
Association/Society
United States
Unspecified amount

St. Ignace Area Community Foundation: CTE Technical Scholarship

The St. Ignace Community Fund annually awards scholarships assisting students with higher education, technical training, vocational training or retraining based largely on acknowledgement of student responsibility, community service, and civic involvement. These Scholarships are made possible through the generosity of donors to the various accounts within the St. Ignace Area Community Fund. Some accounts specifically are awarded to recognize higher education in the areas of special education, vocational/technical careers, teaching, law enforcement, and health care.

Vocational & Trade Education Nursing Special Needs Education +2 more

ANCA-Assoc Vasculitis and Granulomatosis with Polyangiitis Fund

Healthwell Foundation
Private
United States
Up to US $6,000
The ANCA-Assoc Vasculitis and Granulomatosis with Polyangiitis Fund, established by the HealthWell Foundation, aims to reduce financial barriers for underinsured patients suffering from this rare and serious condition. The fund assists with copays, premiums, and out-of-pocket expenses related to treatment, ensuring that affected individuals have access to necessary medications. With over $1.2 billion in grants awarded since 2004, the foundation has helped over 1.1 million patients access critical healthcare services.
Health Care Access & Delivery Rare Diseases Heart Disease

The Role of the Innate Immune System in the Pathogenesis of Type 1 Diabetes

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is advancing Type 1 diabetes research by exploring the innate immune system's role in disease onset. This initiative aims to identify genetic and environmental factors contributing to Type 1 diabetes through multidisciplinary teams. By employing innovative methodologies, the program seeks to determine how immune responses affect pancreatic tissues, potentially leading to early detection and prevention strategies for at-risk individuals.
Genetics & Genomics Diabetes Immune System Diseases

NAFC Patient Care Fund

National Association of Free and Charitable Clinics Inc
Private
United States
US $20,000

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Patient Care Fund

The NAFC Patient Care Fund supports direct patient services that expand immediate access to care. This funding is designed to help NAFC members meet urgent patient needs by supporting clinical supplies, expanded services, contracted providers, transportation assistance, medication access, and other direct care resources.

Patient Care & Services Health Care Access & Delivery Health Facilities & Clinics +1 more

Mercer Vu Farms/ Ron and Judy Hissong Scholarship for Agriculture Fund

The Foundation for Enhancing Communities
Private
United States
Up to US $5,000
The Mercer Vu Farms/Ron and Judy Hissong Scholarship for Agriculture Fund honors Ron Hissong, a dedicated dairy farmer. Established by his family, this scholarship supports students from the Tuscarora School District pursuing education in agriculture or related fields, ensuring they can continue Ron's legacy of community contribution. Applicants must demonstrate financial need and a commitment to agriculture, making this opportunity vital for aspiring agricultural professionals.
Education - Higher Education Academic Scholarship Programs Agricultural Education +2 more

John D. Dixon and Louise A. Dixon Memorial Scholarship Fund

The Foundation for Enhancing Communities
Private
United States
Up to US $2,500
The John D. Dixon and Louise A. Dixon Memorial Scholarship Fund honors the legacy of its namesakes by supporting graduating seniors from Cedar Cliff and Northern York High Schools. This scholarship aims to assist students with a minimum GPA of 2.5 who demonstrate financial need and a commitment to volunteerism or extracurricular activities. It is a one-time award intended to help students pursue higher education at colleges or technical schools.
Education - Higher Education Academic Scholarship Programs Educational Access & Equity +2 more

ECMC Foundation: Grants & Investments

ECMC Foundation
Private
Puerto Rico, United States
Unspecified amount
The ECMC Foundation focuses on eliminating equity gaps in postsecondary education by 2040 through strategic grantmaking and investments. They support organizations aiming to remove barriers to completion, build institutional capacity, and transform the postsecondary ecosystem. Eligible entities include nonprofit organizations, government entities, and postsecondary institutions. However, funding is not available for personal scholarships, political activities, or projects outside the U.S. that do not align with the Foundation's mission of diversity and inclusion.
College Success / Persistence Career / College Preparation Education - Higher Education +1 more

Native Hawaiian Health Care Improvement Act Program

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
United States
US $2,530,712 - US $10,000,000
The Native Hawaiian Health Care Improvement Act Program provides funding to enhance the health status of Native Hawaiians through comprehensive health care services. This initiative supports one administrative award to Papa Ola Lokahi and five awards to certified Native Hawaiian Health Care Systems. The program aims to ensure tailored health promotion and disease prevention services within island communities, addressing specific regional health needs from fiscal years 2027 to 2031.
Epidemiology & Public Health Health Care Access & Delivery Wellness & Healthy Living +2 more

Stanford Childern's Health Center for IBD and Celiac Disease - Intramural Seed Grants Research Program

Stanford Health Care
Private
United States
Up to US $200,000
The Stanford Children's Health Center for IBD and Celiac Disease offers Intramural Seed Grants to promote innovative research in pediatric diseases. This program supports high-risk, high-reward projects, encouraging multi-PI collaborations across disciplines. Awards of up to $100,000 per year for two years are available, aimed at generating preliminary data for future funding applications. Eligible applicants include Stanford faculty holding specific university positions. Proposals should focus on advancing understanding of pediatric IBD and celiac disease through various research approaches.
Digestive System Health & Diseases Maternal And Perinatal Health Children’s Health & Pediatrics

Stanford Medicine Children’s Health Center for IBD and Celiac Disease Postdoctoral and Early Career Support Award

Stanford Health Care
Private
United States
Up to US $200,000
The Stanford Medicine Children’s Health Center for IBD and Celiac Disease offers funding for postdoctoral fellows and instructors to conduct innovative research focused on pediatric IBD and celiac disease. This initiative aims to nurture future researchers and prepare them for independent funding opportunities. Eligible research includes basic, clinical, epidemiological, and health policy studies related to maternal and child health. Funding supports substantial salary and benefits, ensuring commitment to impactful research in this critical area.
Digestive System Health & Diseases Children’s Health & Pediatrics Maternal And Perinatal Health

Big 33 Academic Scholarship Fund

The Foundation for Enhancing Communities
Private
United States
Up to US $2,000
The Big 33 Academic Scholarship Fund, managed by The Foundation for Enhancing Communities, offers financial assistance to Pennsylvania high school seniors planning to pursue higher education. Eligible students must maintain a minimum GPA of 2.0 and demonstrate academic achievement, community service, and leadership. Since its inception in 1985, the fund has awarded over $3.9 million in scholarships, helping countless students achieve their academic goals and overcome obstacles.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs +2 more

Conservation Alliance Grants

Conservation Alliance
Private
United States
Up to US $50,000
The Conservation Alliance Grants program is currently under evaluation, leading to a pause in the member-directed grant cycle as the organization aligns its funding with its strategic plan launching in 2025. This initiative aims to harness the collective efforts of businesses and outdoor communities to protect North America's wild places through impactful and efficient grant-making. Future funding will focus on projects that enhance habitat, support Indigenous initiatives, and address climate change.
Land / Habitat Conservation Outdoor Recreation Climate Change Resilience & Equity

Limited Competition: Tribal Institutional Review Board Establishment and Enhancement (TIRBEE)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Unspecified amount
The TIRBEE funding opportunity supports federally-recognized Tribes and Tribal Entities in establishing or enhancing Institutional Review Boards. This initiative aims to strengthen the capacity for biomedical research involving human participants within these communities by improving review and oversight capabilities. Eligible organizations are invited to apply, with applications subject to NIH's standard peer-review process to ensure only the most meritorious proposals are considered.
Epidemiology & Public Health Native American Services Health Disparities & Social Determinants of Health +1 more

Large Grants for Nonprofit Organizations in District of Columbia Highlights

Looking for large grants for nonprofit organizations in District of Columbia?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in District of Columbia recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in District of Columbia

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ Large Grants for Nonprofit Organizations in District of Columbia grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ Large Grants for Nonprofit Organizations in District of Columbia over $25K in average grant size

100+ Large Grants for Nonprofit Organizations in District of Columbia over $50K in average grant size

55 Large Grants for Nonprofit Organizations in District of Columbia supporting general operating expenses

200+ Large Grants for Nonprofit Organizations in District of Columbia supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in District of Columbia?

Most grants are due in the first quarter.

Q1
28.0%
Q2
25.0%
Q3
25.7%
Q4
21.3%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in District of Columbia?

Grants are most commonly $50,000.

$250 $250 Min.
$50,000 $50 K Median
$326,838 $326.8 K Average
$19,910,496 $19.9 M Max.

Average Grant Size

What's the typical amount funded for District of Columbia?

Grants are most commonly $191,869.

$191,869

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in District of Columbia year over year?

In 2024, funders in District of Columbia awarded a total of 71,691 grants.

2022 71,046

2023 67,427

2024 71,691

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in District of Columbia given out in District of Columbia, the most popular focus areas that receive funding are Education, Human Services, and Community Improvement & Capacity Building.

1. Education

2. Human Services

3. Community Improvement & Capacity Building

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in District of Columbia changing over time?

Funding has increased by 27.77%.

2022 $11,110,524,503

2023 $10,735,067,064
-3.38%

2024 $13,715,894,150
27.77%

District of Columbia Counties That Receive the Most Funding

How does grant funding vary by county?

District Of Columbia receive the most funding.

County Total Grant Funding in 2024
District Of Columbia $12,786,708,728