Best Grant County Grants for Nonprofits in South Dakota

American Headache Society

The American Headache Society (AHS) is a professional society of healthcare providers dedicated to the study and treatment of headache and face pain. The Mission of the AHS is to improve the lives of people impacted by migraine and other headache disorders. AHS advocates for those impacted by headache and the headache field, to meet our core objectives. AHS provides educational courses, scientific meetings, a journal, research support, career development opportunities, Special Interest Groups, advocacy training, and a professional community. The AHS strives to meet its objectives while fostering an inclusive sense of belonging and community.

Headache & Migraine Competitive Grant Program

The Headache & Migraine Competitive Grant Program stands at the forefront of advancing headache medicine by funding groundbreaking quality improvement initiatives. This highly competitive grant program, offered through the collaboration between the American Headache Society and Pfizer, supports projects that have the potential to reshape the field by creating widely applicable tools and driving measurable improvements in patient care. 

Adult Population  RFP (Quality Improvement Solutions for the Diagnosis and Management of Migraine and Headache Disorder)

Seeking projects that drive meaningful impact in headache care through advancements in safety, clinical effectiveness, timely diagnosis, and equitable, patient-centered treatment. Submissions should feature bold, practical solutions in primary care and non-headache specialty settings, supporting adult populations with scalable, real-world innovations. 

The OVW Fiscal Year 2026 Training and Services to End Violence and Abuse Against Individuals with Disabilities and Deaf People Program aims to empower states, local and Tribal governments, and nonprofit organizations to provide crucial training and resources. This initiative focuses on addressing domestic violence, stalking, sexual assault, and caregiver abuse against individuals with disabilities and Deaf individuals, enhancing direct services and support for these vulnerable populations.

The BJA FY 2026 Smart Reentry Demonstration Program aims to support state, local, and tribal governments in implementing effective reentry strategies for individuals transitioning from correctional facilities back to their communities. This program encourages comprehensive interventions designed to reduce recidivism by addressing various reentry needs, as outlined in the Second Chance Act. Applications are due by October 1, 2026, at 8:59 PM ET, and are submitted through JustGrants.

The BJA FY 2026 Harold Rogers Prescription Drug Monitoring Program aims to enhance the capabilities of agencies in collecting and analyzing prescription data for controlled substances. By establishing a centralized database, this initiative will aid in the prevention of drug diversion and abuse, particularly of opioids. The program emphasizes the integration of data with health information exchanges and electronic health records, fostering local decision-making while addressing the needs of tribal and rural areas to combat substance abuse effectively.

The BJA FY26 Body-Worn Camera Policy and Implementation Program aims to assist law enforcement agencies in acquiring body-worn cameras and establishing comprehensive BWC programs. This initiative addresses the increasing demand for reliable video evidence in criminal cases, enhancing documentation and prosecutorial outcomes. By utilizing BWCs, agencies can deter assaults on officers and protect them against false accusations, ultimately improving community trust and accountability in law enforcement practices.

The BJA FY 2026 Investigating and Prosecuting Sexual Assaults in Confinement Facilities Program aims to enhance state, local, and tribal capacities to investigate and prosecute sexual assault incidents within confinement facilities. This funding opportunity is designed for law enforcement and prosecutorial agencies to effectively address and reduce sexual assault occurrences while improving prosecution success rates. Applications are due by September 30, 2026, at 8:59 PM ET.

The BJA FY 2026 Intellectual Property Enforcement Program aims to bolster public health, safety, and the economy by combating counterfeit goods and product piracy. This funding opportunity supports the formation or enhancement of law enforcement intellectual property enforcement task forces. It assists various jurisdictions in tackling intellectual property theft and related crimes, while also aiding in the investigation and prosecution of such offenses, thereby addressing the associated violent crime.

The National Institutes of Health (NIH) is seeking to enhance the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) through the establishment of a Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC). This initiative aims to improve emergency care outcomes by supporting trials that focus on effective treatments for non-stroke neurological and cardiovascular emergencies. Although applications are not currently being solicited, this notice allows potential applicants to prepare collaborative proposals.

The National Institute on Aging (NIA) is inviting applications for the Alzheimer's Drug-Development Program (U01 Clinical Trial Optional). This initiative seeks to support pre-clinical and early-stage clinical development of innovative drug candidates aimed at preventing Alzheimer's disease or treating its symptoms. The program encourages collaboration among researchers and aims to enhance the therapeutic pipeline for AD through targeted approaches. This notice allows potential applicants time to prepare robust projects.

The National Institutes of Health (NIH) is dedicated to advancing emergency care through the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN). This initiative seeks to establish clinical enrollment hubs that will enhance the network's ability to conduct trials aimed at improving outcomes for patients experiencing neurological and cardiovascular emergencies. Although applications are not currently being accepted, this notice encourages potential applicants to prepare collaborative and impactful proposals.

The Established Clinician Investigator Award to Support Mentoring (KS1) is designed to provide established clinician investigators with dedicated time for mentoring early-career clinician research scientists. This initiative by the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to enhance the quality of mentorship, fostering the development of future leaders in clinical research. It supports a sustained commitment to training and guidance, ensuring a robust pipeline of skilled professionals.

The Mentored Career Transition Award (KT1/R00) offers a biphasic funding opportunity for up to 5 years, supporting the transition of postdoctoral researchers to independent faculty positions. The first phase provides 1-2 years of mentored career development, while the second phase grants up to 3 years of independent research support, contingent upon satisfactory progress and faculty appointment. This grant aims to enhance the capacity of early-career researchers in achieving research-intensive roles.

The Mentored Clinician Research Scientist Career Development Award (KC1) from the NIH supports clinician research scientists for up to five years, providing dedicated time for intensive research career development. This award aims to guide candidates with clinical doctoral degrees towards achieving research independence by pairing them with experienced mentors who can help navigate their career paths.

The Mentored Research Scientist Career Development Award (KR1) offers crucial support for researchers aiming for independence. Funded by the US Dept. of Health & Human Services through the NIH, this award allows candidates to engage in intensive research training under a mentor's guidance for up to five years. It is designed for those with research doctoral degrees, facilitating their transition into independent research roles and enhancing their contributions to the scientific community.

The Rural Health Network Development Planning Program aims to enhance rural health care by fostering integrated health care networks. It focuses on collaboration among entities to bolster local capacity and improve care coordination in underserved areas. By achieving efficiencies and expanding access to essential services, the program seeks to strengthen the overall rural health system while promoting the use of health information technology and exploring innovative care delivery models.

The Rural Health Network Development Program aims to enhance health care access in rural areas by supporting integrated health care networks. It offers two funding tracts: the Network Advancement Tract for established networks to overcome operational barriers and the Network Development Tract for early-stage networks to plan and expand services. Both tracts focus on improving care coordination, health outcomes, and operational efficiency, thereby strengthening the rural health care system.

The Rural Maternity and Obstetrics Management Strategies Program (Rural MOMS) aims to enhance access to maternity and obstetrics care in rural areas through collaborative networks. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative focuses on innovative strategies to improve healthcare delivery for mothers and infants in underserved regions, ensuring that quality care is accessible where it is needed most.

The Radiation Exposure Screening and Education Program aims to support organizations in their efforts to screen and educate individuals who have been exposed to radiation from uranium mining and U.S. nuclear weapons testing. This initiative emphasizes the importance of awareness and education in mitigating health risks associated with radiation exposure, ensuring affected communities receive the necessary resources and support for health management.

About Lions Club International FoundationLions Clubs International Foundation (LCIF) provides grants that empower the service of our members. Since its inception in 1968, LCIF has awarded more than US$1.3 billion in grant funding.  Mission :Our mission is to empower Lions clubs, volunteers and partners to improve health and wellbeing, strengthen communities, and support those in need through humanitarian service and grants that impact lives globally, and encourage peace and international understanding. And we fulfill it every day, everywhere we serve.Lions Club International Hunger Grant ProgramHunger Grants focus on strengthening infrastructure and providing essential equipment for Lions’ hunger-relief efforts. These grants empower Lions to support vital initiatives such as school feeding programs, food banks and feeding centers, ensuring that those in need receive the nourishment they require. These grants support infrastructure and equipment acquisition for Lions’ projects focused on alleviating hunger.Grant Examples: 

• Construction or expansion of food banks, feeding centers and food storage facilities.
• Purchase of refrigerators and freezers to store perishable food items.
• Vehicles to transport, collect and deliver food.

Mary O' Neill Mini Grant

Dr. Barbara O’Neill, an AFCPE member and Past President of AFCPE, has made a restricted donation to AFCPE in honor of her late mother, Mary O’Neill, a financially capable woman. The donation will support an annual $5,000 mini-grant for development and implementation of an innovative, high-impact financial educational nonprofit project. 

Winner is notified by October 1 and announced at AFCPE Symposium.

The Vineyard Family Foundation

The Vineyard Family Foundation is the product of decades of work across three generations and five states. Having enjoyed the benefits of our hard work and community patronage, the Vineyard family has chosen to provide to others what so many have graciously provided to us. 

What Sets Us Apart

The Vineyard family has always been committed to its communities. Whether supporting Boys & Girls Clubs, pediatric hospitals, the Ronald McDonald House, arts organizations, or youth recreation leagues, the family has taken a great interest in the care, health, and education of children and the families that nurture them. We take great pride in personally administering our Foundation’s charitable giving, resulting in fewer expenses and more funding for those organizations aligned with the Foundation’s purpose.

Grants

• Supporting Our Communities and Their Families
• Working Towards the Health, Education, and Overall Well-Being of Parents and Their Children

You are steps away from creating an opportunity to receive full or partial funding of your charitable organization. So that you use your time wisely, we offer the following advice for your efforts:

• As a family foundation, we are prohibited from funding individuals or any entity that is not an IRS-recognized Section 501(c)(3) tax-exempt entity or a Section 509(a)(1), (2), or (3) support organization. Thus, while we cannot award a scholarship to an individual, we can fund a 501(c)(3) charity that provides such scholarships.

• If you qualify as a Section 501(c)(3) tax-exempt organization or a support organization pursuant to Section 509(a)(1-3), we will need the IRS Determination Letter confirming as much, as well as a statement signed by your organization’s President or Chief Executive Officer verifying that your organization’s purposes, structure, and operations have not changed substantially since the date of the IRS’s Determination Letter.

• If you are a “supporting organization” under IRS Code section 509(a)(1-3), please provide a list of the public charities that you support. Please also advise whether you are a Type I, Type II, or Type III supporting organization. If you are a Type III supporting organization, please advise whether you are “functionally integrated” with your supported public charity and provide an explanation of that relationship.

Supported Charities

The Vineyard family has historically provided funding for family-related charities such as the Ronald McDonald House, the Boys & Girls Clubs of America, pediatric hospitals, autism-related organizations, and youth recreational leagues. The Foundation looks forward to continuing this support and extending itself to educational, research, and cultural experiences that focus on the needs of children and their parents.

The Air Force Basic Research Sciences Conference and Workshop Support program encourages proposals from U.S. institutions of higher education and nonprofit organizations for conferences and workshops that promote research and technology interchange. These events are vital for sharing recent findings and educational techniques in key scientific areas. The program specifically invites Historically Black Colleges and Universities, Minority-serving Institutions, and Tribal Colleges to participate, aiming to foster collaboration and knowledge exchange among researchers.

The ROSES 2025: D.4 program by NASA focuses on enhancing theoretical and computational astrophysics through collaborative networks. It aims to address grand challenges in Time Domain Multi-Messenger Astrophysics by integrating diverse expertise from various fields. Researchers from U.S. institutions are encouraged to propose innovative tools for modeling complex multi-messenger phenomena, fostering interdisciplinary collaboration across academic, national laboratory, and private sectors to prepare the next generation of scientists.

The IUSE: Innovation in Two-Year College STEM Education (ITYC) program, funded by the National Science Foundation (NSF), aims to enhance STEM education at two-year colleges. This initiative encourages innovative projects that promote student success in foundational STEM courses. Eligible institutions can request up to $500,000 for three years, with an extra $100,000 for those without NSF funding in the last five years, facilitating a total budget of $600,000 for impactful educational projects.

This grant provides essential support to the Tribal Radioactive Materials Transportation Committee, facilitating engagement with the U.S. Department of Energy. The focus is on planning for the transportation of commercial used nuclear fuel and high-level radioactive waste, ensuring that the concerns of federally-recognized Tribal governments are addressed. By fostering communication and collaboration, the initiative aims to mitigate potential impacts on Tribal areas from large-scale transportation activities.

This grant aims to enhance national immunization programs in the Eastern Mediterranean Region by focusing on capacity building, disease control, and outbreak response. It seeks to eliminate vaccine-preventable diseases, reduce morbidity and mortality, and improve access for under-immunized populations. The initiative will promote sustainability through evidence-based decision-making and program evaluation, aligning with CDC goals to address public health threats and improve overall immunization impact in the region.

This grant aims to enhance global polio eradication efforts through innovative modeling approaches. It focuses on developing effective strategies for cVDPV2 outbreak response and optimizing surveillance following global WPV eradication. The initiative also seeks to build a skilled public health workforce in statistical and mathematical modeling, assess economic impacts of response strategies, and foster capacity among students to address polio and other vaccine-preventable diseases.