Creag Foundation Innovation Grants in South Carolina
South Carolina 501(c)(3) nonprofits with innovative human services or health-related programs can seek support to address social problems in new ways. Focused on innovation, Creag Foundation invites organizations with at least one year of 501(c)(3) status to inquire about funding that could strengthen or expand creative approaches to health care and related community services.
Creag Foundation
Hathaway Family Foundation Support for Greenville Healthcare
Nonprofit 501(c)(3) organizations providing healthcare, especially mental and behavioral health services, to those most in need in Greenville County, South Carolina can seek program funding. Hathaway Family Foundation also supports related food access, shelter, and conservation efforts that benefit vulnerable residents in upstate communities.
Hathaway Family Foundation Inc
South Carolina Department of Agriculture Grants for South Carolina Senior Nutrition
South Carolina nonprofits and public agencies providing senior nutrition and food distribution services can receive USDA commodity foods through the South Carolina Commodity Supplemental Food Program, improving low-income seniors’ diets. South Carolina Department of Agriculture administers CSFP statewide, with local agencies handling eligibility, food distribution, nutrition education, and referrals to other health and welfare programs.
South Carolina Department of Agriculture
Yawkey Foundation Grants for South Carolina Health
Focused on capital projects, Yawkey Foundation invites South Carolina 501(c)(3) nonprofits providing direct health care, human services, education, youth athletics, arts, or conservation programs to seek major facilities funding. Eligible organizations in Georgetown County can request up to US $5,000,000 to develop or improve physical spaces that enhance high-quality services.
Yawkey Foundation
South Carolina Community Health Funding via Perdue Foundation
Applications due Aug 1, 2026
South Carolina 501(c)(3) nonprofits working on health, social services, hunger, poverty, education, agriculture, environment, or public safety can access funding via Franklin P. and Arthur W. Perdue Foundation. Grants up to US $1,000 support community-benefit programs, with priority for areas near Perdue facilities and projects endorsed by a Perdue associate.
Franklin P. and Arthur W. Perdue Foundation
South Carolina Systems Change Funding via Sisters of Charity Foundation
Letter of inquiry due Aug 4, 2026
Nonprofit organizations in South Carolina working on systems change for economic mobility or housing security can apply for Sisters of Charity Foundation’s Systems Change Grants, with awards of US $15,000 - US $20,000. Funding can support general operations, programs, or capacity-building, and health care systems change grants are available by invitation only.
Sisters of Charity Foundation of South Carolina
Blue Cross Foundation Support for South Carolina Health
Letter of inquiry due Aug 7, 2026
South Carolina nonprofits, government agencies, and tax-exempt educational or research institutions working on health access and outcomes can seek funding for projects serving economically vulnerable residents. South Carolina health organizations can access funding through Blue Cross and Blue Shield of South Carolina Foundation to improve oral health, mental health, community health education, primary care, and related health care services.
Blue Cross and Blue Shield of South Carolina Foundation
Philip L Van Every Foundation Healthcare Grants in South Carolina
Full proposal due Aug 10, 2026
South Carolina 501(c)(3) health and rehabilitation nonprofits can access funding through the Philip L Van Every Foundation for special projects and capital needs. Grants of US $10,000 - US $50,000 support healthcare, rehabilitation, prevention, wellness, substance abuse services, and related human and community service programs benefiting residents of North and South Carolina.
Philip L Van Every Foundation
Yawkey Foundation Arts and Culture Grants
Pre proposal due Sep 18, 2026
501(c)(3) nonprofits serving children and families through arts and culture programs in South Carolina can apply for Yawkey Foundation’s Program and Small Capital Grants, with awards up to US $100,000 for discrete, timebound projects or equipment. Organizations in Georgetown County may be eligible if they align with the foundation’s arts and culture priorities.
Yawkey Foundation
Yawkey Foundation Grants for South Carolina Health
Pre proposal due Sep 18, 2026
Health-focused 501(c)(3) nonprofits providing direct care, improving access, or addressing health disparities in South Carolina may be eligible for Yawkey Foundation Program and Small Capital Grants up to Up to US $100,000. Focused on health care access, children’s mental health, and social determinants, these competitive grants support discrete, timebound program needs, small projects, or equipment purchases in Georgetown County.
Yawkey Foundation
USDA Rural Development Grants for South Carolina Facilities
Applications due Sep 30, 2026
Public bodies, community-based nonprofits, and Federally Recognized Tribes in South Carolina rural areas can apply for USDA Rural Development’s Community Facilities funding to develop essential community facilities. Support can cover purchasing, constructing, or improving facilities and equipment for health care, public safety, community services, education, utilities, and local food systems in eligible small communities.
USDA: Rural Development (RD)
South Carolina Community Health Funding via Sisters of Charity Foundation
Applications due Oct 5, 2026
Nonprofits and community groups hosting outreach, events, trainings, or workshops that support health care access, housing security, or economic mobility for people experiencing poverty in South Carolina can seek up to US $1,500 in one-time funding. Sisters of Charity Foundation of South Carolina prioritizes grassroots efforts, especially in persistent poverty counties and communities of color.
Sisters of Charity Foundation of South Carolina
Community Foundation Health Grants in South Carolina
Applications due Dec 31, 2026
Nonprofit organizations addressing changing healthcare needs in the CSRA region of South Carolina and Georgia can apply for competitive grants up to US $15,000. Focused on improving health outcomes, Community Foundation for the Central Savannah River Area supports health service education, uninsured medical care, and hospice or homelessness around health care for partners in good standing.
Community Foundation for the Central Savannah River Area
Yawkey Foundation Athletics Grants in South Carolina
Letter of inquiry due Jan 23, 2027
Nonprofit 501(c)(3) organizations providing youth baseball or softball programs and small capital projects in South Carolina can apply for Yawkey Foundation support, with awards up to US $100,000. Grants fund discrete, timebound program needs, projects, or equipment for direct services, with eligibility in Georgetown County within the foundation’s geographic priorities.
Yawkey Foundation
US $250,000 - US $1,000,000
Strategic Growth Funding for Nonprofits from Yawkey Foundation
Letter of inquiry due Jan 23, 2027
Health care and human services nonprofits in South Carolina’s Georgetown County can seek US $250,000 - US $1,000,000 to implement board-approved strategic growth plans. Yawkey Foundation’s Strategic Investment Grants support regional expansion, collaborations, and mergers for organizations delivering direct services in its health care and related priority areas.
Yawkey Foundation
Spartanburg County Foundation Support for Health
Letter of inquiry due Mar 17, 2027
Grants from Spartanburg County Foundation help South Carolina health-focused nonprofits and other 501(c)(3) entities improve quality of life, educational achievement, and economic mobility for Spartanburg County residents. Organizations may receive up to US $35,000 for programs such as physical and mental health services, wellness activities, and related supports that strengthen community well-being.
Spartanburg County Foundation
South Carolina Conservation Funding via Yawkey Foundation
Letter of inquiry due Mar 20, 2027
Nonprofit 501(c)(3) organizations focused on conservation and wildlife projects in South Carolina can seek up to US $100,000 for discrete, timebound program or small capital needs. With a mission to invest in impactful nonprofits, Yawkey Foundation prioritizes direct services in Georgetown County and supports equipment or project-based needs rather than ongoing staff costs.
Yawkey Foundation
Educational Access Funding from Yawkey Foundation
Letter of inquiry due Mar 20, 2027
Nonprofit 501(c)(3) organizations providing higher education access and success programs for underserved young adults may receive up to US $100,000 for discrete, timebound program or small capital needs. Focused on educational access and equity, Yawkey Foundation invites organizations serving Eastern Massachusetts and Georgetown County, South Carolina to apply through its competitive Program and Small Capital Grants.
Yawkey Foundation
Chick Fil A Foundation Grants for Youth
Applications due May 1, 2027
South Carolina health-focused nonprofits serving youth and families can access funding through Chick Fil A Foundation’s True Inspiration Awards, with grants from US $30,000 - US $350,000. U.S. 501(c)(3) organizations working on youth development, food insecurity, housing, or environmental stewardship programs that impact health and well-being may be eligible.
Chick Fil A Foundation Inc
US $100,000 - US $150,000
South Carolina Childhood Trauma Funding via Amerihealth Caritas Foundation
Letter of inquiry due May 13, 2027
South Carolina health and family service nonprofits addressing adverse childhood experiences (ACEs) and related trauma can access funding through Amerihealth Caritas Foundation, with awards of US $100,000 - US $150,000 for one-year, project-specific work. Eligible 501(c)(3)s must serve Medicaid-enrolled communities with comprehensive, community-led programs focused on healing behaviors, health care access, and empowering families.
Amerihealth Caritas Foundation
South Carolina Housing Funding via Enterprise Community Partners
Applications due May 16, 2027
South Carolina housing and community development organizations with proven affordable housing innovations can access funding via Enterprise Community Partners through the National Housing Innovation Grant competition. Eligible nonprofits, mission-oriented for-profits, and housing entities nationwide may apply for US $2,000,000 to scale solutions in design and construction, finance, or service delivery that expand affordable rental and ownership options.
Enterprise Community Partners Inc
Delta Dental Oral Health Grants in South Carolina
Letter of inquiry due May 22, 2027
Health-focused 501(c)(3) nonprofits, government entities, and academic institutions in South Carolina can seek funding for oral health education, prevention, treatment, capacity building, and equipment. Grants from Delta Dental of South Carolina help expand access to affordable, high-quality dental care, especially for children, indigent, rural, and other underserved populations, with awards from US $5,000 - US $100,000.
Delta Dental of South Carolina
Oral Health Funding from Delta Dental
Letter of inquiry due May 22, 2027
Nonprofit 501(c)(3)s, government agencies, and academic institutions improving oral health can seek US $5,000 - US $100,000 for programs, operations, equipment, or capacity building in South Carolina and Missouri. Delta Dental of MIssouri prioritizes projects expanding access to affordable dental care, especially in rural or provider-shortage areas and those with dollar-for-dollar matching funds.
Delta Dental of MIssouri
US $100,000 - US $10,000,000
Digital Health Funding from South Carolina DHHS
Applications due Jun 1, 2027
Eligible organizations in South Carolina can apply for the Rural Health Transformation Program: Connections to Care Initiative, awarding US $100,000 - US $10,000,000 to modernize and expand digital health infrastructure. Funding supports implementation or enhancement of electronic health records and remote patient monitoring within the state’s rural healthcare ecosystem.
South Carolina Department of Health and Human Services
US $50,000 - US $2,000,000
South Carolina Department Grants for Rural Health
Applications due Jun 1, 2027
Rural South Carolina health providers and community organizations can seek funding to expand mobile crisis response and community-based care sites. Focused on rural health care and mental health services, the South Carolina Department of Health and Human Services invites proposals supporting face-to-face care delivery through mobile units, crisis teams, and local wellness sites, with awards from US $50,000 - US $2,000,000.
South Carolina Department of Health and Human Services
Yawkey Foundation Support for South Carolina Human Services
Letter of inquiry due Jun 19, 2027
Nonprofit 501(c)(3) organizations providing direct human services or basic needs support in South Carolina, particularly Georgetown County, can seek up to US $100,000 for timebound program or small capital needs. Grants from Yawkey Foundation help cover discrete projects or equipment that advance core missions serving vulnerable and underserved people.
Yawkey Foundation
Frances P. Bunnelle Foundation Community Grants
Letter of inquiry due Jul 18, 2027
Eligible 501(c)(3) public charities, houses of worship, government entities, and fiscally sponsored projects in South Carolina’s Georgetown County can apply for Frances P. Bunnelle Foundation’s Grants for the Common Good, awarding US $2,500 - US $15,000 for general operating or special projects. Health care access, basic needs, poverty, literacy, environment, and economic vitality programs may be supported.
Frances P. Bunnelle Foundation