Best Capacity Building Grants for Nonprofits in Illinois

Childhood Cancer Research

The grant purpose is to fund one awardee or a research project conducted by Illinois researchers on childhood cancer. The grant award must be used to research childhood cancers or expand current childhood cancer research that must be completed by June 30, 2027. Topics may include, but are not limited to, epidemiology, etiology, pathology, social or economic impacts, in-home care, and psychosocial issues. This is a one-year grant award.

The Fence Authority Scholarship offers a $1,000 award to students pursuing a bachelor’s degree in fields that enhance community beautification, such as architecture, civil engineering, and environmental sciences. Applicants must be U.S. citizens, enrolled full-time, and involved in community service. This scholarship aims to empower students to contribute positively to society while furthering their education in impactful disciplines.

The American Electric Power Foundation provides grants to 501(c)(3) organizations focused on educational improvement, particularly in STEM fields, and basic human services such as hunger and housing. Organizations must operate within AEP's service territory or have a broader beneficial purpose. The Foundation also supports social justice initiatives and environmental protection efforts. Eligible applicants must affirm compliance with anti-discrimination policies and demonstrate commitment to diversity and inclusion.

The Legal Assistance for Nonprofits program by the Chicago Lawyers Committee provides essential legal services to nonprofits and small businesses aiming to reduce systemic inequalities in wealth and access to economic opportunities. This initiative offers support specifically to organizations that advance race equity and serve underserved communities, ultimately helping to close the racial wealth gap through education, legal support, and advocacy for economic development.

Lutheran School Mini Grants

The Foundation continues to encourage congregations to reach out to their surrounding communities through organized, effective social service outreach ministry efforts. We also recognize congregations are looking for innovative ways, outside the traditional social service outreach model, to build relationships and engage their communities.

We look to accomplish this in two ways:

• Supporting congregations as they work to engage and serve their neighbors and community through planning and program implementation grants.
• Strengthening the ability of congregations to engage in community engagement efforts through coaching assistance, mentoring, and training (through Send Me St. Louis).Examples of Possible Ministry Projects

Congregation Community Engagement is defined for this Funding Focus Area as activities, services, or efforts designed to reach out to others on a local level (St. Louis metropolitan region). Examples include both serving the immediate needs of people and efforts to engage and build relationships with the community. The focus is on bringing the care of Jesus Christ into the lives of hurting people in the community, rather than serving the congregation’s own members. This funding focus area is not meant to support “Word and Sacrament” activities.

• Health care/mental health services
• Fitness/healthy living programs
• English as a second language
• After-school mentoring/tutoring
• Social activities for seniors
• Community revitalization
• Recreation activities
• Home repair/beautification
• Partnerships with local schools/other institutions
• Social enterprise/business that benefits the community and/or creates space for relationships
• One-time events (run by the congregation) to meet a need in the community

Idea Exploration

Congregations should know what they want to do and have an idea of how to get started. If you are not at this point, coaching services to assist your congregation are offered through Lutheran Foundation’s relationship with Send Me St. Louis. Services include coaching and guidance on:

• mapping the congregation’s and community’s assets, 
• researching opportunities for social service outreach ministry, and/or
• planning for a social service outreach ministry.

There are no grant deadlines for the Congregation Mini Grants. Application can be made at any time of the year.

The JFNY Grant for Arts & Cultural Exchange supports U.S. non-profit organizations aiming to enhance understanding of Japanese arts and culture. Eligible projects include performances, workshops, and exhibitions, with priority given to those with additional funding and in areas with limited access to cultural events. Applications must be submitted at least one month prior for online projects and three months for others. The grant covers expenses like travel, publicity, and artist fees, and is reimbursed upon project completion.

The Youth Homelessness System Improvement Illinois Prevention Pilot aims to amplify the voices of youth and young adults (ages 18-24) in state governance while addressing youth homelessness. This initiative focuses on enhancing discharge planning, establishing partnerships with community organizations, improving assessment systems, and ensuring equitable responses to youth homelessness. By prioritizing youth leadership and collaboration, the program seeks to create sustainable solutions for at-risk youth, particularly those facing unique challenges such as being pregnant, parenting, or identifying as LGBTQIA.

The CoVantage Cares Foundation Grant supports non-profit organizations in Wisconsin, Michigan, and Illinois that address basic needs and enhance community quality of life. With over $4.2M in funding since its inception in 2015, the foundation prioritizes projects with lasting impact, collaboration, and alignment with its mission. It aims to assist those facing financial challenges while promoting financial literacy and community enhancement initiatives.

The Roy J. Carver Charitable Trust provides grants primarily to 501(c)(3) tax-exempt organizations in Iowa and parts of Illinois. Focused on enhancing educational opportunities, the Trust supports projects in elementary and secondary education, higher education, medical research, youth services, and recreation. By funding innovative initiatives, it aims to improve access to educational resources and foster scientific advancement, while also addressing the recreational needs of youth and supporting community development.

The Illinois Department of Transportation’s Bureau of Safety Programs and Engineering (BSPE) is actively working to meet the goal of zero fatalities on Illinois roadways. In order to make this goal a reality, BSPE offers grant opportunities for funding to state and local agencies and qualified organizations. Due to the size, population, and high traffic volume on Illinois roadways, BSPE partners with state and local agencies and qualified organizations to make this goal a reality.

28-0343-03 State Agency Traffic Records (TR) Program

I. INTRODUCTION

The Illinois Traffic Records Program is designed to improve statewide traffic data systems. The traffic records data systems include the collection, management, and analysis of traffic safety data. It is comprised of six (6) core data systems: crash; driver; vehicle; roadway; citation or adjudication; and EMS or injury surveillance. The six core data systems are commonly referred to as the NHTSA six-pack. Each of the six core data systems must ensure quality of data by measuring the timeliness, completion, accuracy, uniformity, integration, and accessibility of each data system.

II. PROJECT GOAL

Improve the Illinois core traffic data systems: crash; driver; vehicle; roadway; citation or adjudication; and EMS or injury surveillance.

III. GRANT PROPOSAL GUIDANCE

Project proposals submitted must address at least one (1) of the core data systems that make up an ideal traffic records system - crash, driver, vehicle, roadway, citation or adjudication, and EMS or injury surveillance.

Projects must also improve or enhance a miniminum of one (1) of the following in the data systems listed above - timeliness, accuracy, completeness, uniformity, integration, and/or accessibility..

Applicants must provide clear and convincing evidence that the requested project will meet these target objectives. In addition, the applicant must define specific, quantifiable performance measures and certify how these performance measures will be regularly monitored and reported.

The Illinois Works Pre-apprenticeship Program aims to expand opportunities in the construction industry for underrepresented populations, including women, veterans, and people of color. Administered by the Department of Commerce and Economic Opportunity, this program focuses on areas lacking pre-apprenticeship initiatives and encourages participation from historically underserved communities. With funding ranging from $150,000 to $550,000 and an anticipated 35 awards, it plays a vital role in promoting diversity and inclusion within the building trades.

The Norfolk Southern Trades on Track SkillPointe Scholarship offers $5,000 scholarships for students pursuing trades education related to the rail industry. Eligible candidates must be enrolled in a post-secondary institution and focused on railway-related trades. With over 1,000 scholarships funded and a mission to close the skills gap, this initiative empowers individuals towards high-demand careers without requiring a four-year degree, ultimately strengthening the workforce and economy.

The APS Training/Supervision Assistance Grant, offered by the Illinois Department of Commerce and Economic Opportunity (DCEO), aims to support Adult Protective Services through reimbursement for supervision and training. With staffing shortages impacting service delivery, this grant incentivizes hiring and retention by providing funds for caseworker training and supervision. Eligible applicants include county and city governments, nonprofit, and for-profit organizations, ensuring a broad base of support for vital protective services in Illinois.

About PCORI

PCORI funds patient-centered comparative clinical effectiveness research (CER).

Our Mission

PCORI helps people make informed healthcare decisions, and improves healthcare delivery and outcomes, by producing and promoting high-integrity, evidence-based information that comes from research guided by patients, caregivers, and the broader healthcare community.

Broad Pragmatic Studies PCORI Funding

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA), seeking to fund patient-centered comparative clinical effectiveness research (CER) projects. 

Research Initiative Highlights

CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.

Special Areas of Emphasis

For Cycle 2 2026, PCORI is particularly interested in submissions that address the following Special Areas of Emphasis (SAE) within the BPS funding opportunity. The purpose of identifying these SAEs is to encourage submissions to these areas, rather than limiting submissions to these topics. Applicants addressing one of the below SAEs should identify the area that is best associated with their research approach:  

• Addressing Obesity
• Diabetes Prevention, Care and Treatment
• Management of Urogynecological and Pelvic Pain
• Pain Management for Individuals Living With Sickle Cell Disease

In PCORI-funded research, patients and other research partners are expected to meaningfully contribute their lived experience or professional expertise to ensure studies are patient-centered, relevant and useful for healthcare decision making. Applicants must address PCORI’s Foundational Expectations for Partnerships in Research — an evidence-based framework supported by tools and resources to guide effective engagement strategies. Applicants are also strongly encouraged to consider the inclusion of a broad range of patient-centered burdens and economic outcomes. 

Broad Pragmatic Studies PFA: Category 1, Category 2 and Category 3 Study Specifications

PCORI will commit up to $120 million in direct costs through this funding opportunity. This funding opportunity contains three categories for funding:

• Category 1: Category 1 will support research projects with direct costs up to and including $5 million.

• Category 2: Category 2 will support research projects with direct costs greater than $5 million and up to a maximum of $12 million. Applications for funding under Category 2 will be required to provide additional information in the Letter of Intent (LOI) and application to justify the size and scope of the proposed research projects and to explain how additional funds are necessary with respect to the scale, scope and complexity of personnel and material resources needed to address the research question.

• Category 3: Category 3 will support research projects with direct costs up to $12 million that utilize PCORnet® to conduct observational studies and/or pragmatic trials that are national in scale. Category 3 PCORnet Studies® must include two or more Clinical Research Networks and share study progress, performance metrics and best practices with the network to promote continuous learning and improvement. PCORnet Studies® will leverage the PCORnet Common Data Model® as appropriate. Additional details about Category 3 can be found on the PCORI website.  

Enterprise Community Partners

Enterprise Community Partners (Enterprise) is a national nonprofit that exists to make a good home possible for the millions of families without one. We support community development organizations on the ground, aggregate and invest capital for impact, advance housing policy at every level of government, and build and manage communities ourselves. Since 1982, we have invested $80.9 billion and created 1 million homes across all 50 states, the District of Columbia, Puerto Rico and the U.S. Virgin Islands – all to make home and community places of pride, power and belonging.

Midwest Asset Management University Program

Operating, maintaining, and preserving affordable housing is complex and requires a specialized set of skills and a deep organizational commitment to asset management. Today, affordable housing providers face a variety of economic, operational, and compliance challenges, including rising operating costs, rental arrears, staffing shortages, and an aging portfolio.

Enterprise is launching its first Asset Management University (AMU) Program in the Midwest (Illinois, Indiana, Wisconsin, Missouri, and/or Minnesota) in March 2026 to support mission-aligned, affordable housing providers in meeting these challenges in their efforts to provide housing stability to residents and preserve the long-term affordability of properties.

The Midwest AMU is a comprehensive, five-month training program that seeks to strengthen the asset and property management capabilities of participating housing providers, improving organizations’ capacity to oversee the financial, physical, and operational health of their housing portfolios.

Midwest Asset Management University Cohort 

Enterprise is excited to offer this application for participation in the Asset Management University (AMU) Cohort (the “Cohort”). Up to fifteen (15) eligible organizations will be selected for this Cohort and will receive access to online training offered by the Consortium of Housing and Asset Management (CHAM), peer learning opportunities, and post-training technical assistance.

The Illinois Department of Transportation’s Bureau of Safety Programs and Engineering (BSPE) is actively working to meet the goal of zero fatalities on Illinois roadways. In order to make this goal a reality, BSPE offers grant opportunities for funding to state and local agencies and qualified organizations. Due to the size, population, and high traffic volume on Illinois roadways, BSPE partners with state and local agencies and qualified organizations to make this goal a reality.

28-0343-02 State Agency Non-Enforcement Program (SANEP)

I. INTRODUCTION

To aid communities in reducing deaths and injuries on Illinois roads, the Illinois Department of Transportation’s (IDOT) Bureau of Safety Programs and Engineering (BSPE) established the State Agency Non-Enforcement Program (SANEP) grant program. This program is designed to: enable state agencies to increase public awareness and knowledge about highway safety issues; promote safe and healthy driving behavior among underage and adult individuals; provide law enforcement, prosecutorial, and judicial education and training; and/or increase the awareness of the consequences associated with a driving arrest and other sanctions.

II. PROJECT GOAL

The goal of SANEP is to develop and implement effective highway safety programs in Illinois using the strategies of prevention, education, training, outreach, and public awareness.

III. GRANT PROPOSAL GUIDANCE

The SANEP offers grant funds for state agencies to address highway safety issues. The program's main emphasis should be on the education, prevention, training, outreach, and public awareness of highway safety issues to reduce serious injuries and fatalities.

Program applicants must provide clear data supporting the need for the program. Applicants must demonstrate specific ways this program will improve the established problem and how the project will help BSPE meet the performance measures established in the 3HSP and, if necessary, the SHSP. All expenses must be justified and thoroughly explained in the budget narrative.

Asia-Pacific Network for Global Change Research

The Asia-Pacific region, home to over half the world's population, faces challenges due to its development goals, which strain natural resources, communities, and cultural heritage. These issues are exacerbated by adverse environmental changes. While research has shed light on these problems, it's clear that more challenges lie ahead. The Asia-Pacific Network for Global Change Research (APN) is well-positioned to generate new knowledge and solutions for these evolving global change and sustainability issues by supporting collaborative research and scientific capacity development activities, particularly those aimed at training the next generation of early career professionals.

APN 2025 Call for Proposals: CAPaBLE Programmes

CAPaBLE, our scientific capacity development programme, aims to enhance the capacity of scientists, policymakers and practitioners to assess global change issues, and explore options to resolve issues towards achieving sustainability. Through CAPaBLE, we support activities that enhance capacity at individual, organizational and systemic levels.

Activities of interest under the CAPaBLE Programme

APN supports CAPaBLE activities that enhance existing capacities of developing countries at three levels of individual-based capacity development; group, organisation, network-based capacity development; and societies, governance, and system level capacity development. APN accepts CAPaBLE proposals that engage 1 or more member/approved countries. Proposals must address one or more of the following activities:

SCIENTIFIC CAPACITY DEVELOPMENT ACTIVITIES that promote the following approaches related to one or more of the six thematic areas of APN:

• Utilising and strengthening existing capacity, 
• Creating opportunities to use/instil capacity, 
• Developing new capacity through innovative approaches.

AWARENESS-RAISING AND DISSEMINATION activities through policy- and decision-making communities, civil society, and/or the general public.

SCIENCE-POLICY interfacing in the context of the priority topics.

CAPACITY DEVELOPMENT PARTNERSHIP ACTIVITIES that contribute to the capacity development components of the evolving global change arena, including the UNFCCC Paris Agreement, IPCC, IPBES, post-2015 Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction, and the UN Decade of Ocean Science, and ongoing and new global change and sustainability research programmes.

Activities geared towards using SCIENCE COMMUNICATION to disseminate knowledge generated from projects, particularly to non-science audiences.

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality applications. 

Patient-centered CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences. 

The IL Emergency Watershed Protection (EWP) Program aids communities in recovering from natural disasters by providing both technical and financial assistance. It addresses threats to life and property from floods, fires, and windstorms without requiring a federal disaster declaration. Various recovery projects, led by eligible local sponsors, include debris removal, streambank protection, and establishing vegetative cover. The program is designed to be economically and environmentally sound, promoting sustainability in watershed management.

The Great American Cleanup Grants, offered by Keep America Beautiful, aim to enhance community beautification and environmental efforts across the U.S. This initiative encourages KAB affiliates to remove litter, plant greenery, and restore public spaces, contributing to the larger goal of cleaning up 25 billion pieces of litter by 2026. With cash grants available, this program fosters collaboration among communities, promoting sustainable practices and a cleaner, greener future for all.

Radio Flyer is committed to enhancing the lives of children through charitable giving and community support. Their philanthropic efforts focus on 501(c)(3) nonprofit organizations that promote outdoor play and well-being for children. Key initiatives include partnerships with national charities and local organizations, such as building playgrounds for underprivileged kids. Ineligible requests include those from individuals, political groups, and organizations outside the contiguous United States. This ensures that their contributions create lasting positive impacts.

The Climate Change Investment Initiative Grant Program, funded by the Exelon Foundation, aims to support innovative start-ups focused on climate change solutions within Exelon's service territories. With a commitment of $20 million over ten years, the program promotes not only environmental sustainability but also social equality and economic prosperity. Eligible businesses can benefit from substantial equity investments and valuable in-kind services. The initiative seeks to empower diverse leadership teams, particularly those representing women and minorities, to drive impactful change.

The Joyce Foundation's Education & Economic Mobility Grants aim to close income and race disparities in college and career success. The foundation prioritizes equitable access to high-quality education, supporting policies for effective educators, high school graduation, and affordable college credentials. Focused on racial equity and economic mobility, it addresses the needs of historically underserved young people in the Great Lakes region and invests in research, policy development, and advocacy to help them recover from the COVID-19 pandemic.

The Illinois Department of Public Health (IDPH) is launching a funding opportunity aimed at enhancing blood pressure control through community-clinical linkages. This initiative focuses on building partnerships with community organizations to address social service needs, improve health outcomes, and reduce disparities in cardiovascular health. Targeting populations at highest risk of hypertension, the program seeks to foster multidisciplinary collaborations that facilitate access to vital resources and support for better health management.

Student Nursing Respite Pilot Program by ECIAAA

Funding to be used to develop a pilot program between Area Agencies on Aging, aging network providers, and nursing student programs to expand access to respite services for family caregivers of older adults while offering students supervised clinical experience.

Opportunity Funding

• $48,046.00

The Chi-Cal Rivers Fund Grant, administered by the National Fish and Wildlife Foundation, aims to enhance the waterways of the Chicago and Calumet region. This initiative focuses on reducing stormwater runoff through nature-based infrastructure, improving fish and wildlife habitats, and promoting community engagement. The program supports projects under three main categories: habitat quality improvement, stormwater solution expansion, and activation of restored natural areas, encouraging strategic investments for ecological resilience.

The Illinois Children's Healthcare Foundation (ILCHF) aims to ensure every child in Illinois grows up healthy. Committed to improving children's health and wellness, ILCHF supports innovative ideas and partnerships that address emerging needs. While funding is available for novel initiatives, it does not support budget shortfalls, existing program operations, or medical research. ILCHF is dedicated to fostering a healthier future for Illinois children through targeted and impactful funding.