Best Operating Grants for Nonprofits in Illinois

T7 Social Impact GrantsThe T.D. Jakes Foundation (TDJF), in partnership with Wells Fargo, is proud to launch the Social Impact Grant Challenge, a transformative funding opportunity designed to identify, support, and amplify nonprofit organizations creating meaningful change in communities across the United States.

Designed around the T.D. Jakes Foundation's pillars of service (Educational Access & Workforce Readiness, financial inclusion, and community transformation and well-being), the Challenge seeks innovative nonprofit organizations that are addressing critical social issues through impactful, scalable, and sustainable solutions.

Finalists selected through this process will have the opportunity to showcase their organization through a live presentation at the inaugural Thriving Seven (T7) Summit, taking place November 12 –14 in Atlanta, Georgia. In addition to competing for grant funding, finalists will gain national visibility for their work and connect with nonprofit leaders, funders, and changemakers from across the country.Grant Funding: A total of $1,500,000 in grant funding is anticipated to be awarded: 

• One (1) - $500,000 grant
• One (1) - $250,000 grant
• Two (2) - $100,000 grant
• Eleven (11) - $50,000 grant

The Intervention Research to Improve Native American Health (IRINAH), led by the National Institute on Drug Abuse, focuses on enhancing health outcomes in Native populations. It supports research to identify causes of health issues, develop and test effective interventions, and implement strategies that promote sustainability. Emphasizing community strengths, the initiative aims to rigorously evaluate solutions to reduce health disparities, ensuring interventions can be adapted and shared across diverse communities.

The U.S. Army Corps of Engineers (USACE) Engineer Research and Development Center (ERDC) is issuing this announcement for various research and development topic areas. The ERDC consists of the Coastal and Hydraulics Laboratory (CHL), the Geotechnical and Structures Laboratory (GSL), the Environmental Laboratory (EL) and the Information Technology Laboratory (ITL) in Vicksburg, Mississippi, the Cold Regions Research and Engineering Laboratory (CRREL) in Hanover, New Hampshire, the Construction Engineering Research Laboratory (CERL) in Champaign, Illinois, and the Geospatial Research Laboratory (GRL) in Alexandria, Virginia.

The ERDC is responsible for conducting research in the broad fields of hydraulics, dredging, coastal engineering, instrumentation, oceanography, remote sensing, geotechnical engineering, earthquake engineering, soil effects, vehicle mobility, self-contained munitions, military engineering, geophysics, pavements, protective structures, aquatic plants, water quality, dredged material, treatment of hazardous waste, wetlands, physical/mechanical/ chemical properties of snow and other frozen precipitation, infrastructure and environmental issues for installations, computer science, telecommunications management, energy, facilities maintenance, materials and structures, engineering processes, environmental processes, land and heritage conservation, and ecological processes.

The Foundation for Sustainability and Innovation Grant aims to support projects that promote environmental restoration, preservation, and education, with a focus on sustainable resource use and community development. This grant encourages innovative approaches that connect urban and rural settings, enhance biodiversity, and foster creativity in addressing societal challenges. Eligible applicants include IRS-designated non-profits that align with the foundation's vision. The foundation also supports small presses and periodicals that creatively address sustainability issues.

The Goodyear Community Support Grant aims to empower nonprofit organizations that align with Goodyear's community engagement focus areas. With a strong commitment to safe, smart, and sustainable initiatives, Goodyear supports programs fostering safe mobility, inspiring students through education, and addressing environmental and societal needs. This grant serves as a catalyst for positive change, helping communities thrive by focusing on volunteerism and impactful partnerships.

About Us

Who We Are

The National Federation of the Blind is the oldest and largest nationwide organization of blind Americans. Founded in 1940 and currently headquartered in Baltimore, the NFB consists of affiliates, chapters, and divisions in all fifty states, Washington, DC, and Puerto Rico.

What We Do

Through our network of blind members, we coordinate many programs, services, and resources to defend the rights of blind Americans, provide information and support to blind children and adults, and build a community that creates a future full of opportunities.

What We Believe

We are the only organization that believes in the full capacity of blind people and has the power to transform our dreams into reality. We believe in blind people because we are blind people—from our democratically elected leaders to our diverse nationwide membership.

Scholarship Program

Thanks to our generous partners, there are thirty $10,000 merit-based scholarships currently available. All scholarships are awarded on the basis of academic excellence, community service, and leadership. The finalists are announced every spring. They then attend our national convention in July when the winners of each individual scholarship are selected. 

Handid Braille Scholarship

This scholarship is awarded to an individual studying social science, international relations, or governmental affairs. Handid’s mission is to provide Braille and other forms of accessible media to organizations and individuals. The nonprofit specializes in Braille production in languages other than English, especially languages that do not use the Latin alphabet, and wishes to support a student with unique perspectives.

The Professional Formation of Engineers: Research Initiation in Engineering Formation (PFE: RIEF) program aims to foster research in the Professional Formation of Engineers (PFE) while expanding the community of researchers in this field. It targets early-career Principal Investigators (PIs) with limited experience in social science or education research, enabling them to develop expertise in engineering education research and address critical challenges in engineering formation.

The NIAID aims to support four Clinical Trials Networks (CTNs) by funding Statistical and Data Management Centers (SDMCs) to enhance HIV research. These SDMCs will oversee study designs, data collection, and compliance with regulatory standards while ensuring data quality and integration. This initiative is a crucial step toward ending the HIV epidemic, fostering innovative methods, and adhering to NIH data sharing policies. Applications for the SDMCs are now being solicited.

About Us

The American College of Obstetricians & Gynecologists (ACOG) is the leading professional membership organization for ob-gyns. ACOG champions ob-gyns in providing equitable, evidence-based care for patients today and into the future.

ACOG comprises more than 62,000 members across 12 Districts, representing regions in the United States, Canada, and Central and South America. These members maintain the highest professional standards and are united in their delivery of exceptional, respectful, science-backed care for patients. ACOG members include medical students, residents, practicing and retired physicians, and health professionals in related fields.

For nearly 75 years, ACOG has strengthened members with comprehensive, expert-reviewed practice guidelines; management tools; career development resources; and lifelong learning opportunities.

Pete and Weesie Hollis Community Service Award

The Pete and Weesie Hollis Community Service Award (formerly the President’s Community Service Award) was established by then President Richard “Pete” Hollis. The award was an outgrowth of Dr. Hollis’ presidential theme of caring for patients. Dr. Hollis felt strongly that many of the Fellows of ACOG gave hours of care and support within their community to underserved or poorly served patient populations, often with little or no remuneration or recognition.

The award is not to be given as a recognition of activities related to service to ACOG or activities that are based on support of the specialty in legislative or regulatory decisions. Recipients of the award will receive a $1,000 honorarium plus complimentary registration to the Annual Clinical and Scientific Meeting where the award is presented.

The Petit Family Foundation offers General Project Support Grants ranging from $500 to $10,000 to support local communities. Eligible organizations must have 501(c)(3) status and demonstrate programmatic capacity and leadership. The foundation prioritizes measurable outcomes and sustainability, focusing on projects that have a clear impact. Preference is given to local New England-based non-profits, while ineligible requests include funding for individuals, endowments, and political organizations. This initiative emphasizes collaboration and community alignment.

The Heistand Family Foundation Grant aims to empower children in poverty through impactful programs and partnerships. The foundation prioritizes projects that enhance human health, community well-being, and education, focusing on practical applications. Nonprofit organizations and governmental entities are encouraged to apply, particularly those located in the Omaha/Council Bluffs area or western Iowa. This grant supports initiatives that foster job skills and improve the quality of life for disadvantaged children.

The Marion Maccarrell Scott Scholarship, established by Gertrude F. Straub in memory of her father, supports students from Hawai'i public high schools planning to attend college on the mainland. Eligible applicants must demonstrate financial need, possess good character, and maintain a minimum GPA of 2.8. This scholarship encourages studies in fields related to history, government, and international relations, promoting an understanding of world cooperation and peace.

The Mary E. Kwiatkowski Social Services Scholarship Fund, offered by the Erie Community Foundation, supports female and LGBTQIA+ students pursuing social sciences and public service careers. In 2023, over $800,000 was awarded to more than 500 students for post-secondary education. This scholarship aims to eliminate financial barriers for diverse talents in Erie County's social services sector, requiring applicants to submit an essay on their public service aspirations and challenges in the Erie region.

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Grants & Fellowships

Dissertation Mini-Grant

The Mensa Foundation empowers the next generation of researchers through its Dissertation Mini-Grant program.

Designed to support advanced doctoral students, this grant funds innovative studies that broaden our understanding of intelligence, creativity, gifted education, and related fields.

Details

The Mensa Foundation Dissertation Mini-Grant provides $2,500 to advanced doctoral students conducting research on intelligence and gifted education. By funding innovative studies, the grant promotes research that addresses the complexities of intelligence, creativity, and related fields.

Grant Components

The Stark County Dairy Promoters Scholarship Fund, established by the Stark Community Foundation, provides financial assistance to students from Stark County, Ohio. Eligible applicants must be pursuing college-level studies in dairy science, large animal veterinary medicine, human nutrition, or food science, and maintain a minimum GPA of 2.5. This scholarship aims to support the next generation of leaders in these essential fields, fostering educational growth and community development.

Levine Impact Lab

The Levine Impact Lab powers equitable transformation by investing in nonprofit leadership, building community organizations’ capacities, and building their capacity to accelerate positive social and environmental change.

We combine venture-capital expertise and inspired philanthropic thinking to radically amplify the value of giving.

Levine Impact Lab Operational Support Program

The Levine Impact Lab’s Operational Support Program is an 18-month, high-engagement operational partnership designed to help environmental organizations move strategic and financial priorities forward.

At the core of the program is hands-on operational support: our team works side-by-side with your leaders to drive progress on a critical project, whether it’s strengthening your financial infrastructure, increasing earned revenue, or planning for growth.

This is a working partnership. The grant funding and peer-learning community are designed to support and accelerate your momentum.

We are the best fit for organizations that:

• Operate at the intersection of environmental impact and social enterprise
• Are past the startup phase but still in a critical growth stage
• See LIL as a thought partner in unlocking strategy, scale, and sustainability
• Show up with clear goals and a commitment to moving the work forward

More information about participation commitments here.

What is Operational Support?

To get the most out of this program, organizations must come prepared with a specific project, workstream, or organizational challenge they want to tackle over the 18 months with operational support. 

Potential Area(s) of Support: 

• Financial strategy and planning
• Fundraising, development and donor engagement strategy
• Cost structure analysis
• Program development or expansion
• Corporate partnership strategy 
• New location or geographic expansion
• RFP support/capital planning
• Strategic planning
• Board engagement

Find examples of what past cohorts have worked on here.

People

The success of this program relies on having the right organizational leaders at the table. Each organization must commit two senior staff members who are equipped to make key decisions, drive implementation, and stay closely involved throughout the 18-month engagement. These leaders must:

• Have clear decision-making authority and/or strong backing from the Executive Director or CEO
• Be directly involved in the project or challenge the organization is addressing
• Be able to commit time, energy, and focus to move the work forward

There will also be opportunities to include additional staff members in operational projects, as needed, to ensure the right voices and expertise are present. 

Who this might include: Executive Director and Finance Director, Business Development Manager and Operations Lead, or Marketing Manager and Development Director, depending on the nature of your project.

What We Offer

• Tailored 1:1 operational support and strategic advising
• A national cohort of up to 10 organizations
• Peer network of strategic thought partners
• Virtual and in-person workshops and events
• Private Slack channel
• Exclusive alumni programming
• Grant funds over two years
• Supportive peer-learning community
• Accelerated organizational growth and momentum through strategic partnership with LIL

View Program Flyer here.

The Rosenstiel Scholarship, part of the New Mexico Press Women Scholarship Fund, aims to support graduate students in journalism, communications, or law. Established in 2023, it encourages recipients to engage in investigative journalism and uphold First Amendment rights. Eligible candidates must maintain a minimum 3.0 GPA and submit relevant publications, letters of recommendation, and transcripts. This scholarship not only fosters academic excellence but also promotes ethical standards among future media professionals.

The CCRP Initiative invites applications for basic research on chemical threats affecting the nervous system, including chemical warfare agents and toxic industrial chemicals. This funding aims to elucidate toxicity mechanisms, explore new toxic exposure manifestations, and identify targets for therapeutic development. Proposals should generate data relevant to understanding these toxic threats, with applications due by 5 PM local time. Optional Letters of Intent are encouraged 30 days prior to the proposal deadline.

The NIHCM Foundation's Local Media Award honors outstanding local journalism that enhances understanding of health care issues in the U.S. It aims to recognize reports that improve health care affordability, accessibility, and quality. A $15,000 prize is awarded to the winner. Eligible entries must be published in 2025 and focus on local markets, offering insights relevant to health plans and policymakers. This award encourages innovative reporting that addresses the complexities of the health care system.

The Juliette P. Doster Scholarship Fund honors the legacy of Mrs. Doster, who dedicated forty years to improving healthcare in Calhoun County. This renewable scholarship supports students pursuing associate's or bachelor's degrees, as well as approved workforce training programs. Awarded yearly for up to four years, recipients must maintain academic standards. Funding varies based on the Community Foundation's annual income, and the award covers tuition, housing, supplies, and other educational expenses.

The Patient-Centered Outcomes Research Institute (PCORI) will announce the Phased Large Awards for Comparative Effectiveness Research on December 2, 2025. This funding aims to support high-quality, patient-centered comparative clinical effectiveness research projects. The initiative encourages applicants to engage with patients and stakeholders to address critical healthcare dilemmas and improve decision-making. Projects should compare established clinical alternatives with evidence of efficacy, targeting vital health issues across diverse populations.

The Helen M. Heitmann Young Scholar Award, presented by SHAPE America, honors young professionals who have made significant contributions to research in curriculum and instruction within health and physical education. Eligible candidates must be current SHAPE America members and have 3 to 6 years of experience post-doctorate. This award emphasizes active involvement and scholarship in the field, encouraging innovative research that enhances educational practices for preK-12 students.

The Little Giraffe Foundation is dedicated to supporting neonatal health through research grants ranging from $5,000 to $10,000. Since 2011, they have provided substantial resources to hospitals and institutions, focusing on both immediate and long-term health challenges faced by premature infants. Eligible applicants include scientists and healthcare professionals from U.S.-based institutions. The foundation aims to advance research in biological processes, genetics, clinical studies, and more, improving outcomes for vulnerable populations.

The Curriculum and Instruction Honor Award, presented by SHAPE America, recognizes outstanding contributions to health and physical education curriculum research. This prestigious award highlights the importance of effective instructional practices that prepare students for active and healthy lives. Award recipients are selected based on their scholarship in health education and physical education, demonstrating commitment to excellence since the organization's founding in 1885. SHAPE America advocates for quality education and promotes the well-being of preK-12 students across the United States.

The CDC's Comprehensive Suicide Prevention Program for States aims to enhance public health approaches to suicide prevention across the U.S. By targeting high-risk groups, such as veterans and rural populations, the program utilizes data to identify prevention areas, assess existing programs, and implement evidence-based strategies. Key outcomes include improved partner engagement and a measurable reduction in suicide rates. This initiative allows potential applicants to prepare by reviewing relevant data and forming strategic partnerships ahead of future opportunities.

The Encompass Health Therapy Grant offers up to $50,000 for research on the effectiveness of therapies in inpatient rehabilitation facilities. This funding aims to enhance understanding of neurological impairments and improve patient outcomes through evidence-based practices. Eligible projects must be conducted in the U.S. or Puerto Rico, require a defined research protocol, and adhere to ethical standards. The grant prioritizes studies on therapy impact, implementation science, and caregiver education, contributing to the advancement of rehabilitation care.

The Little Giraffe Foundation, a national non-profit based in Chicago, provides NICU Support Grants ranging from $100 to $1,000. Since 2011, they have positively impacted countless families by delivering over 32,000 gift bags and funding essential research. These grants aim to enhance the experience for parents and patients in neonatal intensive care units, supporting initiatives like holiday gift bags and resources for bonding with babies. Applications are welcomed from eligible U.S.-based institutions.