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Best Operating Grants for Nonprofits in Illinois

Find the perfect Operating grants for nonprofits in Illinois on Instrumentl. 10,000+ Operating grants for nonprofits in Illinois in the United States.

10,000+

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$2.95B

Total funding

$5K

Median grant

10,000+ grants
$2.95B total
$5K median

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9,915 Results based on applied filters

NCCF: Survivor Scholarship Program

National Collegiate Cancer Foundation
Private
United States
Unspecified amount

National Collegiate Cancer Foundation

The National Collegiate Cancer Foundation (NCCF) is a national 501(c)(3) nonprofit organization dedicated to supporting young adults diagnosed with or impacted by cancer. Its mission is to provide services, resources, and need-based financial assistance that empower survivors and their families to adopt a resilient “Will Win” mindset throughout treatment and beyond. NCCF is one of the few national organizations that provides direct financial support to young adult cancer survivors, primarily through its Survivor and Legacy Scholarships, which assist students pursuing higher education during or after treatment. The Foundation also promotes cancer awareness and prevention within the young adult community. Recognizing that adolescents and young adults (ages 15–39) face unique challenges—including delayed diagnoses, limited access to insurance and clinical trials, fertility concerns, employment disruption, and social isolation—NCCF prioritizes addressing the significant service gaps affecting this underserved population. Operated entirely by volunteers, NCCF remains committed to advancing educational access, financial relief, and hope for young adult cancer survivors nationwide.

NCCF: Survivor Scholarship Program

The National Collegiate Cancer Foundation (NCCF) Survivor Scholarship Program provides a competitive scholarships to young adults who are cancer survivors or current patients and are pursuing higher education during or after treatment. The program supports students who have demonstrated resilience and continued their educational journey despite the challenges of cancer. Applications are evaluated based on six criteria: demonstration of a strong “Will Win” attitude, quality of essays, financial need, overall cancer survivorship story, commitment to education, and the quality of recommendations. The scholarship recognizes perseverance, hope, and dedication to academic and personal growth.

Education - Higher Education Adult Education Career / College Preparation +1 more

DoW Toxic Exposures Investigator Initiated Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $800,000
The DoW Toxic Exposures Investigator Initiated Research Award aims to fund critical studies addressing diseases linked to military-related toxic exposures. This award supports a wide range of research phases, from basic laboratory investigations to translational research involving both animal models and human subjects. Projects may also explore New Approach Methodologies, enhancing our understanding and treatment options for affected individuals. By facilitating innovative research, this initiative seeks to improve patient care and outcomes.
Environmental Chemistry & Toxicology Environmental Health

Robert Graves Art Scholarship

Community Foundation of North Central Washington
Private
United States
Unspecified amount
The Robert Graves Art Scholarship honors a dedicated educator and artist, Robert Graves, who passionately supported young artists. Open to students from Chelan, Douglas, and Okanogan counties pursuing higher education in visual arts, this scholarship encourages creativity and artistic growth. Applicants must maintain a minimum GPA of 3.0 and submit original artwork. This initiative not only fosters individual talent but also contributes to the cultural enrichment of the community.
Academic Scholarship Programs Arts / Culture Access & Participation Visual Arts +2 more

DoW Toxic Exposures Clinical Trial Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $4,500,000
The FY26 Toxic Exposures Research Program (TERP) Clinical Trial Award supports clinical trials aimed at addressing health issues from military-related toxic exposures. This initiative encourages collaboration through a Partnering Principal Investigator Option, enhancing interdisciplinary research efforts. Projects range from early-phase trials to large-scale studies, focusing on innovative treatments and management strategies for affected populations. The goal is to expedite the translation of research findings into effective clinical applications.
Environmental Chemistry & Toxicology Environmental Health

JFO Music & Cultural Arts Programs

Jewish Federation of Omaha
Private
United States
Unspecified amount

JFO Music & Cultural Arts Programs

This scholarship opportunity is available year-round.

The current program requirements include the following:

  • Scholarships are awarded on a financial-need basis.
  • Scholarships are available only to Jewish residents of the Omaha metropolitan area.
Music Performing Arts Jewish Culture +1 more

Richmond African American Scholarship

The Community Foundation for a Greater Richmond
Private
United States
US $2,000
The Richmond African American Scholarship, established by The Community Foundation for a Greater Richmond, aims to support African American students from public high schools in Richmond. This scholarship provides financial assistance for college expenses and is awarded to students based on academic achievement, leadership, and community involvement. Eligible candidates must maintain a GPA of 3.0 or higher and plan to enroll in a full-time Baccalaureate program at an accredited institution after graduation.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

NCCF: Legacy Scholarship Program

National Collegiate Cancer Foundation
Private
United States
US $1,000

National Collegiate Cancer Foundation

The National Collegiate Cancer Foundation (NCCF) is a national 501(c)(3) nonprofit organization dedicated to supporting young adults diagnosed with or impacted by cancer. Its mission is to provide services, resources, and need-based financial assistance that empower survivors and their families to adopt a resilient “Will Win” mindset throughout treatment and beyond. NCCF is one of the few national organizations that provides direct financial support to young adult cancer survivors, primarily through its Survivor and Legacy Scholarships, which assist students pursuing higher education during or after treatment. The Foundation also promotes cancer awareness and prevention within the young adult community. Recognizing that adolescents and young adults (ages 15–39) face unique challenges—including delayed diagnoses, limited access to insurance and clinical trials, fertility concerns, employment disruption, and social isolation—NCCF prioritizes addressing the significant service gaps affecting this underserved population. Operated entirely by volunteers, NCCF remains committed to advancing educational access, financial relief, and hope for young adult cancer survivors nationwide.

NCCF: Legacy Scholarship Program

The National Collegiate Cancer Foundation (NCCF) offers $1,000 competitive scholarships to young adults pursuing higher education who have lost a parent or guardian to cancer. The award is designed to provide financial assistance and encouragement to students continuing their education despite personal loss. Applications are evaluated based on the applicant’s personal journey, sources of encouragement, demonstrated financial need, notable accomplishments, and the quality of recommendations. The scholarship recognizes resilience, perseverance, and academic commitment in the face of cancer-related loss.

Education - Higher Education Cancer / Oncology Adult Education +1 more

John W. Burandt Scholarship

Rochester Area Community Foundation
Private
United States
US $2,000

Mission & Vision

Rochester Area Community Foundation, in partnership with generous philanthropists and community partners, works to improve the quality of life for people who live and work in the eight-county region through its leadership and strategic grantmaking.

Our Mission:

We are cultivating a thriving Greater Rochester region — powered by philanthropy, grounded in community, and sustained across generations.

Our Vision:

We envision a Greater Rochester region transformed by enduring philanthropy, where every person, neighborhood, and future generation can thrive.

John W. Burandt Scholarship

Purpose of Scholarship

To provide support for tuition, fees, books, and other expenses associated with post-secondary education for dependents of firefighters residing in the city of Rochester, NY.

Number and Size of Awards

One award of $2,000; paid in the Fall and and divided equally between the Fall and Spring semesters.

Donor Information

This scholarship was established by Mrs. Lorene (Rene) Burandt in honor of her husband, John W. Burandt, a dedicated firefighter who served the Rochester community for 30 years.

Firefighting & Fire Prevention Vocational & Trade Education Educational Access & Equity +1 more

Diabetes Innovation Challenge Grant

American Diabetes Association Inc
Private
Cook County, Illinois
Unspecified amount
The Diabetes Innovation Challenge Grant, hosted by the American Diabetes Association, invites emerging companies to propose innovative solutions addressing the daily challenges faced by individuals with diabetes. Participants present their ideas to a panel of experts, competing for the opportunity to implement their visions. The top five applicants are selected to showcase their concepts, while the top ten runners-up can display their pitches during the event, fostering collaboration and advancement in diabetes care.
Diabetes Chronic Illnesses

Mary Lou Lukhard Nursing Scholarship

The Community Foundation for a Greater Richmond
Private
United States
US $1,000
The Mary Lou Lukhard Nursing Scholarship, established by the Community Foundation for a Greater Richmond in 2004, honors Mrs. Lukhard's dedication to nursing. It supports aspiring nurses from Central Virginia, including high school seniors and adult learners. Eligible applicants must demonstrate academic excellence, financial need, and a commitment to community service. This scholarship aims to empower individuals pursuing nursing careers, ensuring a brighter future for healthcare in the region.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

DoW Toxic Exposures Translational Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,500,000
The DoW Toxic Exposures Translational Research Award aims to foster translational research that bridges military-related toxic exposure studies and clinical applications. This program encourages innovative collaborations by allowing for a Partnering Principal Investigator Option, enhancing interdisciplinary partnerships. By integrating basic science with clinical insights, the initiative seeks to expedite the development of impactful health care products and interventions to address toxic exposures faced by military personnel.
Environmental Chemistry & Toxicology Environmental Health

Colleen Maher Inspirational Scholarship

Community Foundation of Northern Illinois
Private
United States
Unspecified amount
The Colleen Maher Inspirational Scholarship supports individuals with intellectual disabilities, aged 18-25, who are current students or graduates of Rockford Public Schools. This scholarship empowers them to pursue post-secondary education and develop skills for independent living. Inspired by Colleen Maher, who overcame challenges associated with Down syndrome, this initiative aims to ensure that others like her can access educational opportunities and work towards their dreams, fostering a more inclusive community.
Academic Scholarship Programs Education - Higher Education Intellectual / Developmental Disabilities +1 more

Patient Reported Outcomes (PROs) RFP

Arthritis Foundation
Private
United States
Up to US $235,000
The Arthritis Foundation is seeking research proposals focused on Patient Reported Outcomes (PROs) to enhance shared decision-making in arthritis care. Projects should aim to deepen the understanding of patient treatment goals, monitor disease activity, and improve communication of PRO data. Research can span various arthritis types, including osteoarthritis and rheumatoid arthritis, and should last up to two years. This initiative emphasizes the integration of patient perspectives to elevate care quality.
Musculoskeletal Diseases Arthritis

Mech SS Carl C. Smith Graduate Student Award

Society of Toxicology
Association/Society
United States
Unspecified amount
The Mech SS Carl C. Smith Graduate Student Award, established by the Society of Toxicology, honors Carl C. Smith's commitment to advancing graduate education in toxicology. This prestigious award encourages graduate students to submit outstanding abstracts for the 2026 SOT Annual Meeting. Eligible applicants must be graduate student members of SOT and PhD candidates who have passed their comprehensive exams. The award promotes diversity and inclusiveness in the field while recognizing exceptional contributions to toxicology.
Environmental Chemistry & Toxicology Environmental Health

James Elwyn Memorial Scholarship

Community Foundation of North Central Washington
Private
United States
Unspecified amount
The James Elwyn Memorial Scholarship, established in 2020, honors James Elwyn's legacy in the Wenatchee Valley swimming community. This scholarship supports graduating seniors from Chelan, Douglas, or Grant Counties pursuing further education. Applicants must demonstrate leadership, commitment to swimming, and a minimum of two years in high school swimming or USA swimming. It aims to recognize students who embody the spirit of teamwork and academic excellence inspired by James's dedication as a teacher and coach.
Education - Higher Education Academic Scholarship Programs Swimming +1 more

TTF Advertising for the Environment Grant

Temper of the Times Foundation
Private
United States
US $5,000 - US $15,000
The TTF Advertising for the Environment Grant, established by the Temper of The Times Foundation in 1997, aims to enhance awareness of wildland conservation through marketing initiatives. This grant is exclusively available to 501(c)(3) nonprofit organizations and funds various advertising campaigns to protect native ecosystems. Priority is given to projects that demonstrate measurable impacts on conservation, rather than those focused solely on education.
Environmental Conservation Habitat & Ecosystem Restoration

Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional) (359650)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Up to US $1,750,000
The National Institute of Environmental Health Sciences (NIEHS) invites applications for the Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional). This program supports interdisciplinary research centers focused on biomedical and environmental science. Eligible institutions must be accredited higher education establishments. Applications are due by 5:00 PM local time, and successful submissions will undergo a rigorous peer-review process to ensure quality and relevance in addressing hazardous substance issues.
Environmental Chemistry & Toxicology Environmental Health

Lam Research Core Values Scholarship

East Bay Community Foundation
Private
United States
US $10,000
The Lam Research Core Values Scholarship, offered by the East Bay Community Foundation, supports high school seniors from specific districts in California and Oregon. Recipients are awarded $10,000 over four years, promoting educational success. Eligible students must exemplify Lam's Core Values, maintain a GPA of 2.7 or higher, and plan to attend a college or technical school. This scholarship aims to empower diverse youth in their educational pursuits and foster community development.
Education - Higher Education Academic Success & Enrichment Academic Scholarship Programs +2 more

Terry Lee Kaylor Memorial Scholarship

Central Kansas Community Foundation
Private
United States
Unspecified amount
The Terry Lee Kaylor Memorial Scholarship, offered by the Central Kansas Community Foundation, aims to assist graduating high school seniors pursuing higher education or vocational training. Preference is given to students from Douglass High School with a minimum GPA of 2.85 and a demonstrated financial need. The scholarship amount varies based on available funds, and recipients will be notified of their award status in May. This scholarship is not renewable and encourages all eligible students to apply.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

Isabel McIsaac Scholarship

Nurses Educational Funds Inc.
Private
United States
Unspecified amount
The Isabel McIsaac Scholarship, awarded by Nurses Educational Funds Inc., supports master's and doctoral nursing students with a minimum GPA of 3.6. Applicants must hold a current RN license and have completed a baccalaureate degree in nursing. Preference is given to candidates pursuing nursing research or organizational studies. This scholarship aims to promote nursing leadership and is funded solely through donations, reflecting over a century of commitment to advancing nursing education.
Education - Higher Education Nursing Mental Health & Psychiatric Diseases +1 more

Innovation Award

American Lung Association
Private
United States
Up to US $150,000
The Innovation Award by the American Lung Association offers $75,000 annually for up to two years, aimed at supporting promising investigators in lung disease research. With a legacy of over 120 years, the Association seeks to fund innovative projects that can significantly impact lung health. Eligible candidates must demonstrate prior excellence in their careers and have held a K or R type award within the last three to five years. This initiative fosters groundbreaking advancements in lung disease science.
Lung Cancer Respiratory Diseases & Systems

Career Guidance for Trainees Grant

Burroughs Wellcome Fund
Private
Canada, United States
US $15,000 - US $25,000
The Career Guidance for Trainees Grant, offered by the Burroughs Wellcome Fund, aims to enhance the career development of early career administrators focused on PhD scientists. This grant supports a workshop that equips participants with research evaluation skills to create impactful career-focused interventions. Participants will receive a $15,000 grant to implement their projects, develop networks, and share findings at national meetings, fostering a diverse scientific workforce essential for research innovation and public service.
Workforce Preparation & Job Readiness Career / College Preparation

AHS Headache & Migraine Competitive Grant Program - Migraine & Women's Health RFP

American Headache Society (AHS)
Association/Society
United States
Up to US $200,000

American Headache Society

The American Headache Society (AHS) is a professional society of healthcare providers dedicated to the study and treatment of headache and face pain. The Mission of the AHS is to improve the lives of people impacted by migraine and other headache disorders. AHS advocates for those impacted by headache and the headache field, to meet our core objectives. AHS provides educational courses, scientific meetings, a journal, research support, career development opportunities, Special Interest Groups, advocacy training, and a professional community. The AHS strives to meet its objectives while fostering an inclusive sense of belonging and community.

Headache & Migraine Competitive Grant Program

The Headache & Migraine Competitive Grant Program stands at the forefront of advancing headache medicine by funding groundbreaking quality improvement initiatives. This highly competitive grant program, offered through the collaboration between the American Headache Society and Pfizer, supports projects that have the potential to reshape the field by creating widely applicable tools and driving measurable improvements in patient care. 

Migraine & Women's Health

Migraine is a prevalent and debilitating neurological disease that disproportionately affects women, impacting quality of life, productivity, and overall health. Recognizing the need for innovative solutions and enhanced care, Pfizer and the American Headache Society (AHS) are collaborating to offer a new grant opportunity inviting proposals for collaborative quality improvement and research projects focused on migraine and women's health.

Chronic / Acute Pain Neurological Diseases & Disorders Women's Health

SESOT Fall Meeting Abstract Submission Award

Society of Toxicology
Association/Society
United States
Unspecified amount
The SESOT Fall Meeting Abstract Submission Award invites submissions for poster or platform presentations at the October 10, 2025 Fall SESOT Meeting in Clemson. Eligible participants include undergraduate, master's, PhD, and postdoctoral trainees who are SESOT members. Awards will be presented for the best presentations at the SESOT Reception during the SOT Meeting in March. New investigators may present but are not eligible for awards.
Education - Higher Education Environmental Chemistry & Toxicology Biomedical informatics

Spencer Educational Foundation: General Grants

Spencer Educational Foundation Inc
Private
Canada, United States
US $5,000 - US $25,000

Spencer Educational Foundation Inc

The Spencer Educational Foundation was founded by the Rims Atlanta Chapter in 1979. To this day, Spencer remains the premier organization funding the education of tomorrow's risk management and insurance leaders.

The Spencer Educational Foundation: awards merit-based scholarships and grants to university students pursuing careers in risk management, insurance, and/or actuarial science; provides grants that create experiential learning opportunities both on and off campus; funds the development of risk management and insurance curricula in colleges and universities; supports Risk Managers by creating internship opportunities within the risk management function of their companies; and operates across the United States and Canada. 

Spencer Educational Foundation: General Grants

Spencer’s goal to help build a talent pipeline of Risk Management and Insurance professionals is achieved in part by our collaboration with Risk Management and Insurance educators across the United States and Canada. Since 2010, Spencer has awarded over $4.5 million in General Grants to support over 225 student-centered experiential learning initiatives at universities and RMI non-profit orgs.

Spencer's General Grants Program supports student-centered initiatives that (1) provide experiential learning opportunities for Risk Management & Insurance students and (2) attract new talent to risk and insurance careers. 

Education - Higher Education Workforce Preparation & Job Readiness Academic Success & Enrichment

The Goodwine Scholarship

Erie Community Foundation
Private
United States
Unspecified amount
The Goodwine Scholarship, offered by the Erie Community Foundation, supports graduating seniors from public or private high schools in Erie County pursuing a two-year associate degree or certificate. In 2023, the foundation awarded over $800,000 in scholarships to more than 500 students, ensuring they have the opportunity to further their education and skills. Applicants must maintain a minimum GPA of 2.0 to qualify for this valuable support.
Education - Higher Education Career / College Preparation Education - High School +1 more

The James R. Herdzik Memorial Scholarship Award

Erie Community Foundation
Private
United States
Unspecified amount
The James R. Herdzik Memorial Scholarship Award, administered by the Erie Community Foundation, offers financial assistance to Erie School District graduating seniors who plan to attend an accredited four-year college or university. This need-based scholarship aims to support students with a GPA of 3.5 or higher who demonstrate a strong commitment to community service. In 2023, over $800,000 in scholarships was awarded to help deserving students pursue their educational goals.
Education - Higher Education Career / College Preparation Education - High School +1 more

Operating Grants for Nonprofits in Illinois Highlights

Looking for operating grants for nonprofits in Illinois?


Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in Illinois recommended for your specific programs.

Grant Insights : Operating Grants for Nonprofits in Illinois

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ Operating grants for nonprofits in Illinois grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ Operating grants for nonprofits in Illinois over $25K in average grant size

100+ Operating grants for nonprofits in Illinois over $50K in average grant size

41 Operating grants for nonprofits in Illinois supporting general operating expenses

200+ Operating grants for nonprofits in Illinois supporting programs / projects

2,000+ Grants on Instrumentl focused on Human & Social Services

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in Illinois?

Most grants are due in the second quarter.

Q1
23.3%
Q2
30.1%
Q3
25.9%
Q4
20.7%

Typical Funding Amounts

What's the typical grant amount funded for Operating Grants for Nonprofits in Illinois?

Grants are most commonly $110,000.

$500 $500 Min.
$110,000 $110 K Median
$1,267,626 $1.3 M Average
$68,450,000 $68.5 M Max.

Average Grant Size

What's the typical amount funded for Illinois?

Grants are most commonly $104,222.

$104,222

Total Number of Grants

What's the total number of grants in Operating Grants for Nonprofits in Illinois year over year?

In 2024, funders in Illinois awarded a total of 104,158 grants.

2022 97,582

2023 97,805

2024 104,158

Top Grant Focus Areas

Among all the Operating Grants for Nonprofits in Illinois given out in Illinois, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Operating Grants for Nonprofits in Illinois changing over time?

Funding has increased by 16.08%.

2022 $8,503,243,276

2023 $9,316,300,812
9.56%

2024 $10,813,952,832
16.08%

Illinois Counties That Receive the Most Funding

How does grant funding vary by county?

Cook County, Lake County, and Macon County receive the most funding.

County Total Grant Funding in 2024
Cook County $6,893,460,213
Lake County $720,580,526
Macon County $544,478,272
Champaign County $541,704,331
Dupage County $496,099,366