Best Large Grants for Nonprofit Organizations in Indiana

The Cystic Fibrosis Foundation offers a Travel Award Supplement aimed at supporting Ph.D. students, postdoctoral fellows, and junior faculty. This funding of up to $3,000 enables trainees to participate in off-site workshops or training programs to enhance their research skills. Eligible applicants must be active researchers in CF projects, with a minimum of one year of experience. The program excludes conference attendance and for-profit entities, ensuring focused support for advancing cystic fibrosis research.

The Harry Shwachman Clinical Investigator Award, offered by the Cystic Fibrosis Foundation, supports clinically trained physicians transitioning to independent researchers in cystic fibrosis. It provides up to $133,000 per year for three years to facilitate research tailored to individual interests. The funding covers personnel costs and supplies, promoting a strong mentorship during this critical stage of their academic careers.

The Path to a Cure (PTAC) - Postdoc-to-Faculty Transition Award by the Cystic Fibrosis Foundation supports postdoctoral fellows in advancing their research careers in cystic fibrosis. This program offers up to five years of funding, including 3 years for research training and 2 years for transitioning to an independent faculty position, with a maximum support of $110,000 per year. It aims to foster innovative research that develops new therapies for cystic fibrosis.

The Cystic Fibrosis Foundation offers the Path to a Cure (PTAC) Postdoctoral Research Fellowship Award to support innovative research training in cystic fibrosis (CF). Aimed at enhancing scientific knowledge and facilitating the transition to independent careers, this program funds projects targeting the development of new therapies for CFTR variants. Awards can reach up to $75,000 in the first year and $76,000 in the second year, fostering foundational research that could lead to breakthroughs in CF treatment.

The Maternal and Child Health Encounters Networks (MCHEK) program, funded by the US HHS: Health Resources & Services Administration, aims to enhance maternal and infant health by preventing exposure to harmful substances throughout pregnancy. Through a national expert call center, it provides evidence-based guidance on medications, nutrition, and environmental factors. By translating complex scientific data into accessible information, MCHEK empowers families and healthcare providers to make informed choices that improve health outcomes.

The Pizza Hut Foundation is offering scholarships for students demonstrating financial need and community leadership. Eligible applicants must be U.S. residents aged 17-26, enrolled in accredited post-secondary education for Spring 2026, and maintain a minimum GPA of 2.5. Scholarship amounts range from $500 to $5,000, with distribution to be made in Spring 2026. The application period runs from July 8 to September 5, 2025, with notifications for recipients by November 17, 2025.

The Talati Family Scholarship Fund, administered by the Community Foundation of Western Massachusetts, aims to support students of color pursuing higher education. Students can apply through a single online application, which connects them to various scholarships based on eligibility. Awards can reach up to $3,000 and may impact financial aid offers. This scholarship is available to undergraduate and graduate students attending accredited institutions in the U.S., particularly those from Franklin, Hampshire, and Hampden Counties.

The William H. Scheide Research Grants, established by the American Bach Society in 1990, support research on Johann Sebastian Bach and his contemporaries. With stipends ranging from $500 to $4,000, these grants are awarded annually and may cover travel and primary source reproduction costs. Preference is given to Ph.D. candidates and junior faculty, but senior faculty are also encouraged to apply. Each recipient receives a one-year membership in the Society, fostering further engagement with Bach's music.

This initiative aims to support research interventions targeting disparities in liver diseases and liver cancer among underserved populations in the U.S. It encourages innovative approaches to reduce health inequities and improve health outcomes. The funding opportunity is available through various deadlines for both standard and renewal applications, promoting multi-level strategies to address these critical health issues effectively.

The NIMH Career Transition Award (K22) supports tenure-track intramural investigators at NIMH in their transition to independent research faculty positions. This program aims to foster innovative research in mental health, encouraging applicants with a strong record of research excellence. Key deadlines for applications vary, including those for standard and renewal submissions, emphasizing the importance of timely applications to secure funding and advance mental health research initiatives.

In 2025, the Community Foundation of Madison & Jefferson County awarded over $233,000 in scholarships to graduating seniors of the county’s public and private high schools. Nearly 50 different students earned money toward their college costs. Scholarships are available for a variety of applicants. Some are specific to schools, majors, need, or interests.

CFMJC scholarships may be used for tuition and related expenses like fees and required equipment at accredited colleges and universities. Room and board are not covered.

Cam Car Club Scholarship

Criteria evaluated:

• Academic performance and financial need

Required materials

• FAFSA SAI PDF upload

Scholarship amount:

• $1,750 | 1 scholarship

In 2025, the Community Foundation of Madison & Jefferson County awarded over $233,000 in scholarships to graduating seniors of the county’s public and private high schools. Nearly 50 different students earned money toward their college costs. Scholarships are available for a variety of applicants. Some are specific to schools, majors, need, or interests.

CFMJC scholarships may be used for tuition and related expenses like fees and required equipment at accredited colleges and universities. Room and board are not covered.

Dupont Alumni Scholarship

Criteria evaluated:

• Academic record, interview, and financial need

Required materials: 

• 2 letters of recommendation from teachers and/or counselors of the applicant’s high school; and 
• FAFSA SAI PDF upload

Scholarship amount:

• $3,900 | Multiple scholarships may be awarded

The PATH Scholarship, established by the Ellucian Foundation in 2020, aims to support higher education institutions in assisting students facing financial hardships. With over $2.9 million awarded, it has benefited more than 3,100 students. Eligible institutions can receive grants ranging from $10,000 to $25,000, with individual awards up to $1,500. This initiative encourages public two-year colleges, particularly Minority Serving Institutions, to apply and adapt award criteria to meet the needs of their students.

Grand Traverse Regional Community Foundation

The Grand Traverse Regional Community Foundation began in 1992 when a group of community champions came together around a vision to give back to our region then, now, and forever.

This vision lives on within our organization today as we support the people and places of Antrim, Benzie, Grand Traverse, Kalkaska, and Leelanau Counties and the Grand Traverse Band of Ottawa & Chippewa Indians.

Together with our partners, we spark positive change for a variety of local causes, including youth, arts and culture, education, environment, and health and human services, across our region.

Traverse City Area Public Schools (TCAPS) Scholarships

The Community Foundation is home to a variety of scholarships designated to benefit a graduating senior from Traverse City Area Public Schools (TCAPS). 

The Les and Anne Biederman Foundation, Inc. Scholarship Fund (Central, West)

In keeping with the visions and determinations that were held by the late Les Biederman, this scholarship is available to students who endeavor to pursue careers in nursing or business.

One scholarship awarded annually at each Central and West for a student pursuing a career in business and one scholarship awarded annually at each Central and West for a student pursuing a career in nursing.

The Society of Toxicology offers the Supplemental Training for Education Program (STEP), which provides up to $1,000 to support graduate students in toxicology seeking additional training to address skill gaps. Eligible applicants must be PhD students who have completed coursework and passed comprehensive exams. The funding covers workshops or courses not available through their graduate program, enhancing career prospects in toxicology.

The Clinical Investigator Career Development Award offered by the Lymphoma Research Foundation aims to support early-career physician researchers in developing new lymphoma therapies. With a total funding of $375,000 over three years, the program provides salary support and incidental funds for research supplies and professional development. Eligible candidates must have no more than six years of experience post-training, focusing on clinical research design and implementation to enhance their skills and career trajectory.

The American Epilepsy Society offers Research and Training Fellowships for Clinicians, providing up to $75,000 for one year to support clinical fellows or new faculty aiming to advance in epilepsy research. This fellowship encourages proposals across basic, translational, and clinical research. It also includes $1,000 for travel to the AES Annual Meeting, membership benefits, and complimentary registration, fostering collaboration and knowledge sharing in the epilepsy research community.

The Autism Care Today Grant provides vital funding assistance to families affected by Autism Spectrum Disorders across the United States. Since its inception in 2005, it has supported over 1,562 families with more than $1.85 million in grants. The program focuses on enhancing the quality of life for children with autism through various initiatives, including safety measures, assistive technologies, and behavioral therapy funding, while also addressing the unique challenges faced by military families.

The Alvin V. Palmer Scholarship Fund, established by the Community Foundation of Central Georgia, honors the legacy of Alvin V. Palmer, a dedicated veteran and entrepreneur. This fund provides financial support for college and technical school scholarships to current and former residents of Greene County, Georgia. With a commitment to enhancing educational opportunities, this scholarship aims to empower deserving students from Mr. Palmer's hometown to achieve their academic goals.

The Autism Care Today SOS Program is dedicated to providing immediate assistance to families affected by autism across the United States. Established in 2005, this program addresses urgent needs for effective treatments and services for autism spectrum disorders. Unlike typical grant cycles that may take up to 12 weeks, the SOS Program prioritizes those in critical situations, ensuring timely support based on available funding. Eligibility includes a family income below $45,000 and a demonstrated immediate need for treatment.

The Andee Jorgensen Scholarship, managed by the Renton Regional Community Foundation, supports students from King County demonstrating financial need and resilience against personal hardships. With an award of $1,000, this scholarship honors civic leader Andee Jorgensen and is available for high school, undergraduate, and graduate students. Preference is given to those engaged in community service. The foundation aims to foster education and empower local youth to pursue their academic ambitions while overcoming challenges.

The Minnesota STEM and Youth Leadership Grants, offered by the H.B. Fuller Company Foundation, focus on empowering young individuals through STEM education and leadership development. These grants are intended for tax-exempt organizations that serve communities near H.B. Fuller facilities, aiming to address racial inequities in education and employment. The initiative underscores the company's commitment to community support and creating opportunities for youth to thrive in science, technology, engineering, and mathematics fields.

Napa Valley Community Foundation

There are more than 800 Community Foundations in the US, each devoted to a specific region. We operate independently, with a common goal in mind: to be a platform for local people who want to pay it forward. To deliver resources to effective charitable programs. And to make our communities stronger and more successful by doing these two things.

Among our peers, Napa Valley Community Foundation ranks first on several key measures of donor satisfaction and impact, according to a recent donor survey conducted by the Center for Effective Philanthropy. Our donors say that we deeply understand their interests, and deeply understand the needs of Napa Valley. That, in a nutshell, is our job.

Dr. Rick Bachman Memorial Veterinary Medicine Scholarship

The Dr. Bachman Memorial Scholarship Fund celebrates the life of Dr. Richard Wayne Bachman, DVM, a distinguished veterinarian and beloved mentor. Affectionately known as “Dr. B” by colleagues and “Ricky” to friends, his commitment to animal welfare extended beyond his role as Lead Veterinarian at Napa Humane. He was notably involved in their weekend Wellness Clinics, serving the underserved, low-income, Spanish speaking community. Dr. Bachman was also deeply invested in the education of future veterinarians and vet technicians. This fund reflects his dedication to animal health, community service, and the nurturing of upcoming veterinary professionals.

The Dr. Rick Bachman Memorial Veterinary Medicine Scholarship Fund is made possible by Napa Humane and benefits current or former residents of Napa County, Solano County, or Lake County. This scholarship is geared towards veterinary students who are committed to practicing companion animal veterinary medicine and plan to give back to their community after graduation. Recipients must attend an accredited veterinary college or veterinary technology program and will receive funding for up to two years while working to complete their degree.

Marshall High School Scholarship

The Alison Shuemake Scholarship is for a Marshall High School senior and graduates pursing an academic or technical degree or certification.

Applications are open year-round. After we receive all application requirements, we internally review applications and make decisions within two weeks of receipt. An email will be sent to the applicant to complete follow up requirements.

Scholarship payments are sent directly to the school.

The Pediatric Cancer Research Foundation (PCRF) offers Donor Designated Grant Programs aimed at funding innovative projects addressing childhood cancer. These grants support researchers dedicated to finding cures, enhancing treatment, and improving care. With an annual commitment to extraordinary researchers, PCRF ensures funds are directed towards promising advances in prevention and treatment. Since 1982, PCRF has raised over $51 million, significantly impacting survival rates and striving to eliminate childhood cancer through collaborative efforts and cutting-edge research.

Enterprise Community Partners

Enterprise Community Partners is a national nonprofit that exists to make a good home possible for the millions of families without one. Home is where life happens, where plans are made, and futures begin. It is the foundation for dignity, health, education, wealth, and community. Yet rents keep going up, paychecks don’t keep pace, and good homes in strong neighborhoods are increasingly out of reach.

The system doesn’t work. It must be changed, and it must be changed by us.

Enterprise has the breadth, scale, and expertise to do it. We support community development organizations on the ground. We aggregate and invest billions to improve housing and strengthen communities across the U.S. We advance housing policy at every level of government. We build and manage communities ourselves. Everything we do is informed by the residents we serve.

Together with our partners, we focus on the greatest need — the massive shortage of affordable rental homes — to achieve three goals:

• Increase the supply of affordable homes
• Advance racial equity after decades of systematic racism in housing
• Support residents and strengthen communities to be resilient to the unpredictable, and make upward mobility possible

Since 1982, we have invested $92.0 billion and created 1.1 million homes across all 50 states, the District of Columbia, Puerto Rico, and the U.S. Virgin Islands. We do all this to make home and community places of pride, power, and belonging.

National Housing Innovation Grant Competition

Home is foundational. It’s where we plant roots, raise and care for our families, and build community bonds. Yet in every corner of the country, millions of people of all ages and backgrounds need a home they can afford.

Wells Fargo is meeting this moment with a powerful grant opportunity. Together with Enterprise, Wells Fargo has launched the third iteration of the Housing Affordability Breakthrough Challenge. The 2026 cycle of the housing innovation competition will identify and propel proven, ready-to-scale solutions that transform current practices and increase housing choice and access.

Eligible applicants will compete for five individual grants of $2 million to advance their innovation and drive meaningful, systems-level change in the housing and adjacent industries. Winners will gain access to mentorship and coaching from industry leaders and experts and join a powerful network of Breakthrough Challenge innovators.

Focus Areas

This third cycle of the Housing Affordability Breakthrough Challenge aims to meet the nation’s affordable housing challenges across all types of communities: Native, rural, suburban, tribal, and urban.

Proposals must encompass one or more of three focus areas:

• Design and Construction
• Finance
• Service Delivery and Programs

Applicants will be asked to show how their proof of concept or pilot program has achieved clear outcomes and success, and provide a clear pathway to expanding the innovation’s reach and impact

Round 1: Criteria and Scoring

Your innovation must meet the criteria below to advance to the official scoring stage.

Type of Community

Innovations can serve all types of communities:

• Rural
• Urban
• Suburban
• Tribal

Location

Priority scoring will be given to applications from entities that are based in – or whose innovations are designed for – one or more of these 28 states, plus D.C.:

• Alaska, Arizona, Arkansas, California, Colorado, Florida, Georgia, Idaho, Illinois, Iowa, Maryland, Massachusetts, Minnesota, Montana, Nevada, New Jersey, New Mexico, New York, North Carolina, North Dakota, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, Utah, Virginia, Washington, Washington D.C.

Affordability

Innovations must serve residents at these income levels:

• Rental: 80% AMI or below
• Homeownership: 120% AMI or below
• Workforce housing: 120% AMI or below

The AO Spine NA Young Investigator Research Grant Award supports early-career surgeons and researchers focusing on clinically relevant spinal or spinal cord research. With funding of $20,000, this initiative encourages new investigators by providing essential start-up capital. Successful applicants are required to present their findings at the Annual AO Spine North America Fellows Forum and submit progress and final reports detailing their research outcomes. This grant aims to foster innovation and excellence in spinal care.