Best Large Grants for Nonprofit Organizations in Indiana

The Lymphoma Research Foundation's Postdoctoral Fellowship Grants support early career researchers dedicated to lymphoma research. Awarding a total of $195,000 over three years, the grant focuses on hypothesis-driven studies relevant to Hodgkin and non-Hodgkin lymphoma. Eligible projects include laboratory and clinical research, with a strong emphasis on significant contributions to understanding lymphoma's etiology, immunology, and treatment. Grantees are expected to dedicate 80% of their time to research, ensuring impactful advancements in the field.

The Christina Sue Lilja Resource Grants support agricultural literacy by providing funds for educators to purchase resources from the Ag Foundation store. In 2025, 100 educators will receive $100 in store credits, selected randomly if applications exceed this number. This initiative, backed by the CSL Foundation, honors Christy Lilja's legacy of advocating for agricultural education. The grants aim to enhance classroom resources and improve students' understanding of agriculture, ensuring access to accurate information.

The Hillman Emergent Innovation Grant offers $50,000 for 12-18 months to support innovative nursing-driven interventions for underserved populations facing health care access barriers, including racial minorities and low-income individuals. It encourages fresh, early-stage ideas targeting serious illness and end-of-life care challenges. By fostering community engagement and interdisciplinary collaboration, the program aims to transform care delivery in diverse settings, ensuring equitable health services for all.

The Anna B. Glauser Trust Grants provide financial support to organizations aiding physically handicapped individuals, particularly blind residents in Delaware County, PA. Established in memory of Willis K. Glauser, the trust awards 1-2 grants annually, ranging from $2,500 to $5,000. Eligible organizations must be 501(c)(3) certified, while funding for salaries is typically excluded. This initiative reflects Anna Glauser's lifelong commitment to assisting the visually impaired community.

The CFF/NIH R01-Unfunded Award, offered by the Cystic Fibrosis Foundation, supports exceptional CF-related research projects that have been submitted to NIH but lack funding. This program aims to bridge the gap for meritorious projects, providing up to $125,000 per year for two years. By facilitating research in cystic fibrosis, the foundation helps ensure that innovative ideas can continue to progress toward improving care and outcomes for individuals affected by this disease.

The APA Congressional Fellowship offers psychologists a unique opportunity to engage in public policy, enhancing the application of psychological knowledge in government. Over a year, fellows work alongside Congress members, drafting legislation and participating in oversight activities. The fellowship is available for APA members, with stipends ranging from $75,000 to $90,000, in addition to health insurance reimbursement and professional development funds. This initiative aims to support psychologists interested in societal challenges and policy issues.

The Society of Family Planning is offering the Bridging Investments in Abortion and Contraception Research Grant to support the completion of NIH grants focused on abortion and contraception. This funding aims to mitigate the impact of recent funding terminations by ensuring that vital research continues, promoting equitable access to reproductive health. Proposals can request up to $100,000 and must detail their alignment with the Society's mission, planned activities, and budget within a 24-month timeline.

The CF Foundation/NIH K-Unfunded Award aims to support exceptional research projects in cystic fibrosis (CF) that have been approved by the NIH but lack funding. This award provides temporary financial assistance of up to $80,000 per year for two years to ensure that promising CF research continues without interruption. The initiative focuses on fostering a new generation of researchers dedicated to advancing CF studies while encouraging the NIH to provide long-term support.

The Emily Hall Tremaine Exhibition Research Grant supports innovative projects that explore contemporary art in new frameworks. With a focus on education in the United States, the foundation emphasizes the importance of research that challenges conventional thought. Grants of $10,000 are awarded to curators collaborating with established non-profits, promoting impactful exhibitions. The foundation aims to foster family unity and respect while addressing enduring societal issues through art, environment, and learning differences.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is announcing a Notice of Funding Opportunity (NOFO) for Diabetes Research Centers (DRCs). These centers aim to foster collaboration among diabetes researchers, enhance preclinical and clinical research, and provide access to specialized resources. Emphasis is on innovative scientific themes and collaborative projects in areas such as Immunology and Artificial Intelligence. Although applications are not currently solicited, potential applicants are encouraged to prepare for future submissions.

The Friends of Reservoirs: Small Grant program offers annual grants of $2,000 to member organizations of Friends of Reservoirs, with additional product donations bringing the total value over $3,500. This initiative, supported by generous sponsors, aims to enhance reservoir fisheries habitats. Applicants should note a $25 application fee, which contributes directly to the grant fund. This program focuses on fostering community engagement and improving aquatic ecosystems.

The Foellinger Foundation offers Community-Based Grants aimed at enhancing early childhood, youth, and family development in Allen County. The foundation focuses on nonprofit organizations that provide essential services to families in need. Grants are awarded based on specific program outcomes and prioritize those with a proven track record. Organizations must be at least three years old and exempt from federal taxes. This initiative aims to promote self-reliance and community building through targeted support.

The Klingenstein Third Generation Foundation's 'Transformation of Mental Health Care Program' seeks innovative research into improving mental health care access for children and adolescents, particularly from under-resourced backgrounds. Applications are invited for studies that build on promising pilot work, focusing on scalable delivery models and technology use. Eligible applicants are academic researchers based in the U.S. who can demonstrate rigorous research capabilities. The foundation plans to award up to two grants of $100,000 each year for two years.

The Hilda M. Hill Memorial Scholarship is offered by the Four County Community Foundation to support high school seniors and recent graduates from Capac, Almont, and Imlay City. Eligible students planning to pursue vocational or technical programs may apply, with financial need considered. Recipients will be recognized at the Foundation Scholarship Celebration in May, as well as during high school awards ceremonies. Students can receive up to two awards, promoting continued educational advancement in skilled trades.

The Stephan D. Weiss Student Mental Health Award, established by the American College Health Foundation, aims to enhance mental health support for college students. Offering $5,000 annually, it encourages innovative initiatives that can improve mental health service delivery and student retention. Eligible applicants are members of the American College Health Association, focusing on identifying mental health needs and developing effective campus-wide strategies. This award addresses growing concerns regarding mental health issues in higher education, fostering a supportive learning environment.

The We Are Moving The Needle Scholarship supports women, trans, and non-binary creators in the music industry by offering two full scholarships for a masterclass with GRAMMY-nominated producer Alissia in Paris. This initiative aims to empower underrepresented voices through education and mentorship, fostering a more inclusive music industry. Participants will engage in hands-on workshops designed to enhance their production skills and gain insights from a leading industry professional, contributing to lasting cultural change.

The Inspired to Serve Scholarship Fund honors Seigo and Hisaye Kagawa, providing support for Kauai residents pursuing graduate studies in social justice, public service, education, or health. Established in 2016, it aims to assist students who demonstrate financial need, maintain a GPA of 3.0, and commit to full-time studies at colleges in Hawaii or the mainland. This initiative encourages future leaders to engage with their communities and contribute to meaningful change.

The Biocodex Microbiota Foundation invites early career researchers in the microbiome field from U.S. institutions to apply for the 2024 grant. This initiative focuses on groundbreaking research into gut microbiota's role in human health and disease, particularly in areas like circadian rhythms and metabolic disorders. The grant supports operational costs, allowing for innovative projects aimed at fostering independent research careers in microbiota studies.

The Houston Marathon Foundation Grant supports running-related programs and initiatives, especially those that promote health and fitness in the greater Houston area. Organizations can submit unsolicited Letters of Inquiry, which must be pre-approved before submission. The Foundation prioritizes funding for programs that demonstrate fiscal responsibility and operational integrity, and applications are reviewed quarterly. Additionally, programs aiding elite athlete development outside Houston may also be considered.

The AGA-R. Robert & Sally Funderburg Research Award in Gastric Cancer aims to support established investigators in gastric cancer research. This award focuses on enhancing the understanding of gastric cancer pathobiology and developing strategies for prevention, treatment, and cure. Eligibility includes holding an MD or PhD, with specific experience requirements. The American Gastroenterological Association encourages applications, particularly from underrepresented groups in biomedical research, to foster diversity in the field.

The Pizza Hut Foundation is offering scholarships for students demonstrating financial need and community leadership. Eligible applicants must be U.S. residents aged 17-26, enrolled in accredited post-secondary education for Spring 2026, and maintain a minimum GPA of 2.5. Scholarship amounts range from $500 to $5,000, with distribution to be made in Spring 2026. The application period runs from July 8 to September 5, 2025, with notifications for recipients by November 17, 2025.

The Russell Sage Foundation's Race, Ethnicity, and Immigration Grant Program funds innovative research on the intersections of race, ethnicity, and immigration. It aims to explore how these factors influence social, economic, and political outcomes for various populations, including immigrants and U.S.-born minorities. Projects should focus on original data collection, rigorous research designs, and address critical questions regarding diversity, policy impacts, and intergroup relations. Funding caps are set at $200,000, promoting multifaceted approaches in social science research.

The Spotlight Fund Grants aim to enhance racial equity in K-12 education by providing flexible funding to BIPOC educators. With grants ranging from $500 to $1,000 per educator, these funds are essential for sourcing tools and materials that support diverse student needs. As schools face budget cuts exacerbated by COVID-19, this initiative focuses on proven strategies that foster an inclusive learning environment for students of color, ensuring they have equal opportunities to thrive.

The Autism Speaks Predoctoral Fellowship aims to support early career autistic scientists in their research endeavors. By providing a two-year fellowship that includes a $40,000 annual award, the program seeks to enhance research training opportunities for promising candidates. Fellows will collaborate with leading mentors in autism research, ensuring that individuals with both academic expertise and lived experience can significantly contribute to advancements in the field. This initiative underscores Autism Speaks' commitment to fostering inclusivity and innovation in autism research.

The Tri-M Foundation's Performing Arts Grant Program aims to support innovative and high-quality performing arts projects by regional non-profit organizations. The program prioritizes projects that align with the organization's mission, engage audiences, and provoke important discussions. Grants range from $3,000 to $10,000, intended for diverse artistic expressions, including theatre and dance. Applications are encouraged from eligible organizations that demonstrate detailed project planning, inclusivity, and a commitment to addressing sensitive topics.

The 2026 Innovation Grant by Alex’s Lemonade Stand Foundation aims to foster groundbreaking research in pediatric oncology. This grant provides crucial seed funding of up to $250,000 over two years to established researchers proposing innovative ideas that have the potential to significantly impact childhood cancer treatment. The program emphasizes clinical translation and encourages novel approaches that diverge from previous research directions, ensuring a focus on impactful solutions for children battling cancer.

The Sherry Wagner-Henry Board Fellowship, initiated by the United States Institute for Theatre Technology (USITT), offers a unique opportunity for emerging leaders in the theatre and entertainment industry. This 12-18 month program connects Fellows with experienced board members to enhance their professional skills. Participants gain access to board resources, attend meetings, and receive support for conferences, all valued at approximately $3,000 to $3,500. Ideal for individuals with 2-5 years of experience, this Fellowship fosters growth and leadership in nonprofit governance.