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Best Large Grants for Nonprofit Organizations in Indiana

Find the perfect Large Grants for Nonprofit Organizations in Indiana on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in Indiana in the United States.

10,000+

Available grants

$2.62B

Total funding

$5K

Median grant

10,000+ grants
$2.62B total
$5K median

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Gamma Mu Foundation Grant

Gamma Mu Foundation
Private
United States
Up to US $15,000
The Gamma Mu Foundation, established in 1988, aims to support the LGBT community in rural and underserved areas through various grants. Initially focused on HIV/AIDS projects, it now funds scholarships and services for diverse LGBT subpopulations. With over $2 million awarded, the Foundation prioritizes initiatives that enhance community support, public education, and health programs. It emphasizes projects that build organizational capacity and provide essential services where resources are limited, ensuring ongoing support for vital health and social services.
LGBTQIA+ Services HIV / AIDS Sexuality & LGBTQIA+ Rights

Cancer-Related Behavioral Health Fund

Healthwell Foundation
Private
United States
Up to US $2,000
The Cancer-Related Behavioral Health Fund, established by the HealthWell Foundation, provides financial assistance to individuals diagnosed with cancer for behavioral health treatments. This fund covers costs associated with prescription drugs, counseling services, and transportation. Aiming to alleviate financial burdens, it ensures that underinsured patients can access necessary care without delay. In 2024, the foundation awarded over $1.2 billion, emphasizing its commitment to improving health outcomes for cancer patients across the United States.
Cancer / Oncology Crisis Intervention Health Care Access & Delivery +2 more

National Girls and Women in Sports (NAGWS) Legacy Award

Society Of Health And Physical Educators
Private
United States
US $1,000
The National Girls and Women in Sports (NAGWS) Legacy Award, established by SHAPE America, honors exemplary contributions to increasing opportunities for women in sports. This annual award recognizes current SHAPE America members who submit impactful proposals related to women's sports, with a monetary prize of $1000. The award will be presented at the National Convention & Exposition, with a special deadline of November 1st. Nominations can include various initiatives aimed at empowering women in sports.
After School / Summer Educational Programs Women & Girl Services Sports & Athletics +5 more

BFOA Monthly Grant

Broadcasters Foundation of America
Association/Society
United States
Unspecified amount
The Broadcasters Foundation of America Monthly Grant provides essential financial assistance to broadcasters facing acute hardships due to serious illnesses or accidents. This initiative aims to support those who have dedicated significant years to the broadcasting profession, ensuring they receive medical aid and relief from financial burdens. Eligible applicants can apply for monthly grants if they meet specific employment and hardship criteria, helping them navigate difficult times with dignity and support.
Children’s Health & Pediatrics Crisis Intervention Health Care Access & Delivery +4 more

Barney Family Foundation Grant

Barney Family Foundation
Private
United States
US $5,000 - US $50,000
The Barney Family Foundation Grant focuses on improving early education and advancing medical research, particularly in cancer and Alzheimer’s. It supports organizations that demonstrate a clear plan to enhance children's life experiences and educational opportunities for those in grades K-8. Grants typically range from $5,000 to $50,000, prioritizing established entities while welcoming startups. Eligible applicants must have 501(c)(3) status, and the Foundation does not fund individual requests or political activities.
Education - Preschool / Early Learning Education - Middle School Education - Elementary School +2 more

Center for Family Engagement Healthy Minds Fellowship

National Congress of Parents & Teachers
Corporate
United States
US $1,000
The Center for Family Engagement Healthy Minds Fellowship, organized by the National PTA, invites active PTA leaders to enhance their mental health expertise over a 12-month cohort starting January 2026. Participants will receive a $1,500 stipend and engage in developing actionable plans to improve mental health initiatives in schools. This fellowship aims to empower leaders through workshops and collaborative efforts, fostering a supportive environment for mental wellness in educational settings.
Child Welfare Services Children’s Mental Health Parenting Counseling & Education +2 more

Tribal Colleges Extension Program Special Emphasis

USDA: National Institute of Food and Agriculture (NIFA)
Federal Government
United States
US $50,000 - US $200,000
The Tribal Colleges Extension Program Special Emphasis (TCEP-SE) aims to enhance community engagement through pilot projects at 1994 Institutions, targeting issues like agricultural productivity, food systems, and public health. This program is open to a wide range of Tribal colleges and universities, promoting workforce development and youth involvement in agriculture. By addressing local needs, TCEP-SE fosters community vitality and prepares the next generation of Tribal agriculture leaders.
Agriculture Workforce Preparation & Job Readiness Youth Development & Leadership +2 more

Impact100 Cincinnati

Impact 100 Inc
Private
Adams County, Ohio, Boone County, Kentucky +8 more
US $100,000
Impact100 Cincinnati empowers women to enhance lives in Greater Cincinnati by funding transformative grants focused on culture, education, environment, family, and health. They aim to address community needs with measurable goals, ensuring grants are utilized effectively over 1-3 years. Eligible organizations must be 501(c)(3) charities and align projects with the mission of Impact100. The initiative fosters collaboration while prohibiting funding for operating costs, travel, and faith-based advancements.
Community Culture & Heritage Education Recreation +6 more

Systemic Sclerosis with Interstitial Lung Disease Fund

Healthwell Foundation
Private
United States
Up to US $9,000
The Systemic Sclerosis with Interstitial Lung Disease Fund, managed by the HealthWell Foundation, aims to reduce financial barriers for underinsured patients suffering from systemic sclerosis. This rare autoimmune disease leads to excessive collagen production, causing serious health issues. The fund assists with prescription copays and insurance premiums to ensure patients receive necessary treatments. In 2024, HealthWell awarded over $1.2 billion in grants, supporting more than 1.1 million patients in accessing vital healthcare services.
Cardiovascular Diseases & Systems Neurological Diseases & Disorders Multiple Sclerosis +3 more

Quest for Healthy Communities Champions Grant

Quest Diagnostics Foundation Inc
Private
United States
US $10,000

Quest Diagnostics Foundation

Established as a 501(c)(3) nonprofit organization, the Quest Diagnostics Foundation is committed to addressing the systemic root causes of health disparities. By combining corporate resources with trusted community leadership, we fund and scale evidence-based initiatives that promote wellness, prevent chronic disease, and empower individuals.

We focus our resources on three critical, interconnected clinical and social interventions to build sustainable health improvement:

  • Strengthening the community health workforce
  • Addressing social drivers of health (SDoH)
  • Promoting the prevention, early detection, monitoring, and treatment of disease through diagnostic testing

About Quest for Healthy Communities Champions

The Quest for Healthy Communities Champion award was created to honor, uplift, and support outstanding organizations across the United States that are actively living our core purpose:

Working together to create a healthier world, one life at a time.

Whether you are expanding access to life-saving screenings, supporting maternal and family wellness, or addressing critical social drivers of health, your dedication is moving us closer to an equitable healthcare future. We want to recognize and celebrate your impact.

What we celebrate: Our core impact pillars

The Champions we look to honor are community-first organizations and coalitions tackling critical disparities head-on. We are especially excited to spotlight work that advances health, addresses social drivers of health, fosters community-clinical linkages and develops the community workforce. Examples of this work could include: 

  • Programs actively dismantling clinical barriers to ensure every individual—regardless of zip code, background, or income—has access to high-quality care
  • Innovators providing creative solutions for food security, transportation, health education, and maternal-child support networks
  • Organizations bringing critical care directly to those in need through mobile clinics, community health workers, and localized diagnostic screenings
  • Organizations finding creative ways to engage the communities they serve directly into the solutions they are delivering

The award: Selected organization champions will receive a $10,000 grant.

Health Policy & Advocacy Children’s Health & Pediatrics Maternal And Perinatal Health +3 more

Ethel Strickarz Memorial Scholarship

Community Foundation of Elmira-Corning and the Finger Lakes, Inc.
Private
United States
Unspecified amount
The Ethel Strickarz Memorial Scholarship aims to address community needs through educational support in special education and related fields. Funded by the Community Foundation of Elmira-Corning and the Finger Lakes, it encourages students pursuing careers in human services, nursing, psychology, speech pathology, or therapy. This scholarship reflects a commitment to holistic community development by fostering future professionals dedicated to improving lives and addressing urgent societal challenges.
Psychology Nursing Physical Therapy +3 more

Frank R. Kleffner Lifetime Clinical Career Award

American Speech Language Hearing Foundation
Private
Countries
Unspecified amount

About the ASHFoundation

ASHFoundation supports innovators and sparks innovation in communication sciences. We give early support to promising students, researchers, and clinicians exploring bold ideas to transform the field and improve people's lives.

Frank R. Kleffner Lifetime Clinical Career Award

The Frank R. Kleffner Lifetime Clinical Career Award recognizes an individual’s outstanding contributions to communication sciences and disorders over a period of at least 20 years. The lifetime contribution may have been in clinical service, supervision or administration of clinical service, clinical research, or any other activity that has promoted clinical excellence.

The award is given in honor of Frank R. Kleffner, a former ASHFoundation president and former ASHA president, who worked tirelessly over his lifetime until his passing in 2015 to professionalize and expand the ASHFoundation’s charitable goals.

The awardee receives a commemorative art object with a recognition plaque.

Communication Disorders Hearing Disorders & Audiology Speech-Language Learning & Disorders +1 more

Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed) (357250)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,500,000
The Chemical Countermeasures Research Program (CCRP) Initiative aims to support vital research on the harmful effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids, including fentanyl and its combinations. This funding opportunity encourages studies that enhance understanding and mitigation strategies for these substances, focusing on both immediate and long-term health impacts. Applications are due by 5:00 PM local time, with optional Letters of Intent accepted 30 days prior to the proposal deadline.
Drug Use Disorder Addiction & Substance Use Disorders Drug Safety

WWA Scholarship Program - HDR One Water Institute Scholarship

American Water Works Association (AWWA)
Association/Society
North America
US $10,000
The HDR One Water Institute Scholarship, offered by the American Water Works Association, provides $10,000 in funding to support graduate students pursuing degrees that will lead to careers as consultants in the water industry. This initiative highlights the importance of investing in future water professionals and fostering innovative research to address pressing water challenges.
Sanitation & Clean Drinking Water Water Resource Management Academic Scholarship Programs

AWWA Scholarship Program - Hazen Scholarship

American Water Works Association (AWWA)
Association/Society
North America
US $10,000
The AWWA Hazen Scholarship supports graduate-level candidates dedicated to improving water quality and resources. Awarded by the American Water Works Association, this scholarship aims to empower future leaders in the water industry. Candidates must demonstrate commitment to addressing critical challenges in drinking water, water reuse, and sustainable practices. This initiative reflects AWWA's mission to invest in the next generation of water supply professionals, ensuring a sustainable future for water resources.
Sanitation & Clean Drinking Water Water Resource Management Academic Scholarship Programs

Homeless To Housing Program - Financial Assistance

Disabled Veterans National Foundation
Private
United States
Up to US $2,000

Disabled Veterans National Foundation

The Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability.

Guided by this commitment, DVNF developed its Health & Comfort programs, offering emergency financial assistance, housing transition support, food assistance, comfort kits, and wellness initiatives. These programs are designed to meet veterans where they are and to provide practical solutions that restore hope and stability. Today, DVNF continues to grow as a trusted national nonprofit. Every day, our team works with a clear purpose: to change lives for the men and women who have served our country.

Homeless To Housing Program - Financial Assistance

DVNF is dedicated to assisting disabled and at-risk veterans in their transition from homelessness to permanent housing. Recognizing that securing a home is a significant milestone, DVNF understands that true stability is achieved when a house becomes a home, furnished with essential items that provide comfort and functionality. We help cover essential costs related to securing and creating comfortable housing for at-risk veterans.

The H2H Program offers comprehensive support to veterans by providing: Financial Assistance of up to $2,000 to cover essential costs related to securing permanent housing, such as security deposits and initial rent payments.

For Financial Assistance: Payments are processed through two payment cycles each month, around the 15th and 30th. If your payment is delayed beyond the expected date, a Promissory Note of Payment will be issued to the vendor, confirming our organization's responsibility and requesting that no penalties be applied to the applicant.

Homelessness Services Equitable & Affordable Housing Supportive Housing & Shelters +1 more

AWWA Scholarship Program - Mueller HBCU Scholarship

American Water Works Association (AWWA)
Association/Society
North America
Unspecified amount
The AWWA Scholarship Program, specifically the Mueller HBCU Scholarship, supports undergraduate students from historically black colleges and universities pursuing careers in the water sector. Offered by the American Water Works Association (AWWA), this scholarship recognizes the vital role of future professionals in addressing water industry challenges. AWWA aims to invest in students who will contribute to sustainable water management and innovation within their communities.
Sanitation & Clean Drinking Water Water Resource Management Academic Scholarship Programs

AWWA Scholarship Program - Carollo Engineers Bryant L. Bench Scholarship

American Water Works Association (AWWA)
Association/Society
North America
US $10,000
The AWWA Scholarship Program, specifically the Carollo Engineers Bryant L. Bench Scholarship, offers a $10,000 award to graduate students dedicated to advancing their careers in the water consulting engineering field. Established in honor of Bryant L. Bench, this scholarship aims to support future leaders who will enhance drinking water quality through innovative engineering solutions. The American Water Works Association emphasizes the importance of investing in students to secure the future of the water industry.
Sanitation & Clean Drinking Water Water Resource Management Academic Scholarship Programs

Harris & Frances Block Foundation Grant

Harris and Frances Block Foundation
Private
United States
Up to US $35,000
The Harris and Frances Block Foundation, established in 2001, supports small grassroots organizations focused on social and environmental justice. They prioritize equitable solutions and sustainable community development, funding initiatives related to environmental education, justice, and food security. Grants are available to non-profit, tax-exempt organizations in specific geographical areas including Vermont, North Carolina, Virginia, and New York City, excluding funding for lobbying, land acquisition, and scholarships.
Food Access & Hunger Environmental Justice & Advocacy Agricultural Education +2 more

NIH Brain Development Cohorts (NBDC) and Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH is offering access to biospecimens from the ABCD, HBCD, and PATH studies to promote research on health and disease across a lifetime. This initiative encourages projects that utilize these samples to deepen understanding of genetic and environmental influences, particularly substance exposure. Researchers can submit proposals to maximize the scientific utility of these resources, in alignment with the goals outlined under federal health regulations.
Addiction & Substance Use Disorders Drug Use Disorder Human Genome & Genetics

Jennie Wade Scholarship Endowment

Community Foundation of Wabash County
Private
United States
Unspecified amount

About Us

Our Mission

We create lasting impact through asset development, nonprofit capacity building, and community leadership. 

Our Vision

To enrich the lives of Wabash County residents by fostering opportunity, inspiring generosity, and building a thriving connected community. 

Our Scholarships

For High School Seniors & Non Traditional Students who are beginning college more than one year after high school.

The Community Foundation of Wabash County offers a wide variety of post-secondary education scholarships to traditional, non-traditional, and graduate students. With nearly 70 different scholarship endowments created through the generosity of our donors, many students are eligible to apply.    

Jennie Wade Scholarship Endowment

More than one hundred years ago, Jennie Wade created a scholarship in her words “to benefit mankind.” This scholarship is made to help young men and women continue their education after high school. Wabash County residents under the age of 21 are selected from among applicants who have done as much as possible in helping themselves obtain an education and whose families are unable to provide an education.

Workforce Preparation & Job Readiness Career / College Preparation Education - Higher Education +3 more

Scholarships for Graduate Students: AWWA Abel Wolman Fellowship

American Water Works Association (AWWA)
Association/Society
Canada, Mexico +1 more
Up to US $30,000
The AWWA Abel Wolman Fellowship, established in 1984, supports highly qualified students conducting meaningful research in water supply through doctoral programs. Named after Dr. Abel Wolman, this prestigious award recognizes excellence and creativity in the water sector. The fellowship provides up to two years of financial support, with an initial award of $30,000 for the first year, aimed at fostering the next generation of water professionals in the U.S., Canada, and Mexico.
Sanitation & Clean Drinking Water Water Resource Management Academic Scholarship Programs

Dean John A. Knauss Marine Policy Fellowship

Woods Hole Oceanographic Institution (WHOI)
Private
American Samoa, Guam +4 more
Unspecified amount
The Dean John A. Knauss Marine Policy Fellowship offers a unique opportunity for early career professionals to engage in marine and Great Lakes science and policy within the U.S. government. This one-year, paid fellowship encourages graduate students from accredited programs to explore impactful coastal resource issues. Interested applicants should connect with their local Sea Grant program or the National Sea Grant Office for guidance, especially if they are from Massachusetts, to ensure a competitive application.
Marine Biology Marine / Ocean Conservation Environmental Policy +2 more

Loene Pooler Guthrie Scholarship Fund

Benton Community Foundation
Private
United States
Unspecified amount

Loene Pooler Guthrie Scholarship Fund

The Loene P. Guthrie Scholarship fund benefits music students in Benton, Linn, and Lincoln counties who plan to engage in the teaching of piano, voice, and orchestral music.

This scholarship fund promotes the teaching of piano, voice and orchestral music by aiding music students in Benton, Linn, and Lincoln Counties who plan to engage in the teaching of piano, voice, and orchestral music. Students who will graduate from Linn, Benton, or Lincoln County high schools or graduates of those high schools currently studying music at an institution of higher learning may apply. The Linn-Benton Chapter of the Oregon Music Teachers Association reviews the applications and selects individuals to perform at an audition open to the public.

Performing Arts Music Education Symphony / Orchestra

NIDDK High Risk Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34 Clinical Trial Optional) (351692)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
The NIDDK High Risk Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34) aims to support high-risk, multi-center clinical studies by facilitating early peer review and assessment of study designs. This program helps in the development of necessary operational documents and essential elements for conducting hypothesis-driven studies focused on diseases relevant to NIDDK. Applications are due by 5:00 PM local time, and consulting with NIDDK staff is strongly encouraged.
Diseases & Conditions Digestive System Health & Diseases Kidney Diseases +1 more

Harry C. Anthony, Jr. Scholarship

Delaware Community Foundation
Private
United States
US $2,500

Harry C. Anthony, Jr. Scholarship

Essay:

  • Describe yourself and explain why you are interested in a career in medicine.

Awards:

  • One-time award of $2,500
Musculoskeletal Diseases Skeletal Diseases Arthritis +1 more

Large Grants for Nonprofit Organizations in Indiana Highlights

Looking for large grants for nonprofit organizations in Indiana?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Indiana recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Indiana

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Large Grants for Nonprofit Organizations in Indiana grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

49 Large Grants for Nonprofit Organizations in Indiana over $25K in average grant size

37 Large Grants for Nonprofit Organizations in Indiana over $50K in average grant size

33 Large Grants for Nonprofit Organizations in Indiana supporting general operating expenses

200+ Large Grants for Nonprofit Organizations in Indiana supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

400+ Grants on Instrumentl focused on Disaster Relief / Humanitarian Aid

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Indiana?

Most grants are due in the second quarter.

Q1
24.6%
Q2
28.1%
Q3
23.6%
Q4
23.7%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Indiana?

Grants are most commonly $14,375.

$375 $375 Min.
$14,375 $14.4 K Median
$429,344 $429.3 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Indiana?

Grants are most commonly $158,271.

$158,271

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Indiana year over year?

In 2024, funders in Indiana awarded a total of 42,920 grants.

2022 40,294

2023 39,261

2024 42,920

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Indiana given out in Indiana, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Indiana changing over time?

Funding has increased by 35.58%.

2022 $4,633,293,808

2023 $4,997,384,462
7.86%

2024 $6,775,520,204
35.58%

Indiana Counties That Receive the Most Funding

How does grant funding vary by county?

Marion County, Monroe County, and Tippecanoe County receive the most funding.

County Total Grant Funding in 2024
Marion County $5,951,081,269
Monroe County $587,464,361
Tippecanoe County $370,158,455
St Joseph County $332,109,828
Allen County $235,684,076