Best Large Grants for Nonprofit Organizations in Indiana

The Substance Abuse Prevention, Treatment, and Aftercare program aims to combat substance abuse in American Indian and Alaska Native populations. It focuses on enhancing care coordination, expanding culturally competent behavioral health services, and implementing early intervention strategies for at-risk youth. By supporting Tribal and community-led initiatives, the program fosters collaboration among families, youth, and community partners to create effective prevention, treatment, and recovery solutions.

The Jean T. Grant Scholarship, established by The Columbus Foundation, honors the legacy of Jean Terry Grant, a devoted librarian and arts advocate. Providing $1,000, this scholarship supports graduating seniors from Columbus City Schools pursuing studies in music or the arts. Jean's commitment to education and the arts inspires future generations, ensuring that her passion for creativity and philanthropy continues to impact the community positively.

Scholarships

Grand Haven Area Community Foundation scholarships are awarded competitively based on criteria set by donors. These criteria could include financial need, the school the applicant is attending, academic achievement, as well as personal or career goals. The Community Foundation has a rigorous internal selection process for each scholarship decision, and each applicant is reviewed in depth, and considered thoroughly.

Our scholarship program is simple. You are able to apply once for all foundation scholarships you may be eligible for. Once your application is submitted, you will be eligible for all those for which you meet the requirement.

Allendale Community Foundation Scholarship

This scholarship was established by the Allendale Community Foundation and Allendale Charter Township as a way to support a graduate residing in Allendale Charter Township who wishes to pursue a post-secondary education.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing Type 1 diabetes research by exploring the innate immune system's role in disease onset. This initiative aims to identify genetic and environmental factors contributing to Type 1 diabetes through multidisciplinary teams. By employing innovative methodologies, the program seeks to determine how immune responses affect pancreatic tissues, potentially leading to early detection and prevention strategies for at-risk individuals.

About

Mission, Vision & Values

To enhance our community through philanthropy.

We aspire to co-create diverse, meaningful and innovative charitable giving that yields an exponential positive impact within local communities and beyond.

David Bruce Belcher Fund

About the fund

The David Bruce Belcher Scholarship Fund was established for the training of professionals in nursing, special education, and therapy (physical, speech and occupational) as a legacy of David Bruce Belcher and the caregivers who comforted him. This fund reflects David’s rare spirit and bright love in its support of those who seek to advance their nurturing skills in nursing, therapy, and special education.

The National Cancer Institute (NCI) invites applications for studies on mechanisms by which bariatric surgery influences cancer risk. This funding opportunity encourages exploration beyond short-term outcomes like weight loss and diabetes. The goal is to support innovative proof of concept studies, emphasizing feasibility without prior development in the literature. Unpublished data is not allowed, but references from preprints with a DOI are acceptable. Deadlines for applications span from February 2025 to November 2027.

The National Cancer Institute (NCI) is seeking applications for studies that explore how bariatric surgery influences cancer risk, emphasizing the need for innovative research in this area. This funding opportunity encourages the participation of researchers who focus on the long-term impacts of bariatric surgery beyond weight loss and diabetes, addressing critical gaps in understanding the disease mechanisms involved. Key deadlines for application submissions span from February 2025 to October 2027.

The John H. and Ruby M. Laurie Charitable Scholarship offers a $1,000 scholarship to graduating seniors from Camdenton High School with a minimum GPA of 3.5. This renewable scholarship supports students enrolled in accredited colleges or vocational schools, encouraging academic achievement. Preference is given to those pursuing a Business degree. This initiative aims to enhance community welfare through educational support and resource development, fostering future leaders in the region.

The Daland Fellowships in Clinical Investigation, awarded by the American Philosophical Society, support research in clinical medicine across various fields, including internal medicine and psychiatry. Each fellowship provides $40,000 annually for up to two years, contingent on satisfactory progress. Eligible candidates include those with recent M.D. or Ph.D. degrees, and applicants must conduct research under a scientific advisor in the U.S. Preference is given to those with limited postdoctoral training.

Shawnee Fine Arts Club Scholarship

Provides a scholarship to graduating seniors of Shawnee High School, Liberty Academy, or home-schooled residents of Shawnee, Oklahoma with a minimum cumulative GPA of 2.7. Student must be accepted into the university of their choice, majoring in music, visual arts, dance, or drama.

Herold and Retta Reuss Public Safety Scholarship

Applicants must demonstrate the drive and ability to be successful in pursuing a college education and/or a certification process in the fields aforementioned. Financial information is requested, but not necessarily a determining factor. Students who receive this scholarship may apply for further support in subsequent years.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a student who is matriculating in a performing arts program, has demonstrated commitment to their art, and has demonstrated evidence of community involvement and service to others.

Mission Statement

Beckley Area Foundation exists to inspire and facilitate generous charitable giving that advances our community.

The Beckley Area Foundation is committed to enriching lives and strengthening communities across Southern West Virginia.

Scholarship

Supporting Student Success

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

Surayria T. Hasan Scholarship

Eligibility

Both need and merit will be considered in selecting applicants; Must be a minority student from Raleigh County, West Virginia; Pursuing either a masters in nursing degree, a nurse practitioner degree, or physician’s assistant degree at a West Virginia school, preferably in Raleigh County.

Multiplex Platforms to Assess Indicators of Micronutrient Status, Inflammation and Infectious Disease

The Challenge

Although combined immunological measurement of several micronutrient biomarkers has been demonstrated, current methods still have important limitations. These include heterogeneity in the composition of standards and controls; inconsistent batch-to-batch performance of analyte-binding molecules; variable reactivity for some analytes, especially soluble transferrin receptor (sTfR); and a functional analytical range that is too narrow to cover the physiological values of some analytes, such as CRP. It would also be valuable to add bioindicators for vitamins B1, B2, B9 and B12, which may require binding molecules that recognize metabolites or proteins associated with deficiency, a specific vitamer (plasma methyl-tetrahydrofolate without reacting with folic acid), comparable reactivity across vitamers (several folate forms in red blood cells), or a specific carrier-protein form (holo-transcobalamin rather than apo-transcobalamin or haptocorrin for vitamin B12).

The improved assays must combine high analytical specificity, sensitivity and robustness with a functional analytical range matched to the physiological values expected in the target populations (women of reproductive age, including during pregnancy and lactation, preschool-age children and older adults). Assays must remain low-cost (no more than US$20 for all analytes measured in duplicate) and require very small sample volumes, preferably less than 10 µL of plasma or serum). The tests are intended for population surveillance rather than local clinical (point-of-care) use. They should be designed to run many samples in a single batch in a small number of national or regional reference laboratories. The goal is to reduce dependence on expensive, infrequent population surveys and on export of samples to specialized laboratories in high-income settings.

This challenge is structured around two alternatives, a minimum-scope approach and an optimistic-scope approach. Targets are aligned with the candidate Target Product Profile for this platform, and applicants will be held to the relevant performance, cost and instrument targets.

Our Impact

UNCF was founded in 1944 to help more African American students attend and graduate from college.

Since then, we've helped to more than double the number of minorities attending college.

For Students

UNCF is more than just scholarships. We’re the nation’s leading minority education organization and our goal is to help you get to and through college.

Our support takes many different forms. From merit scholarships to financial assistance, on-campus assistance to professional development, emergency financial aid to community support, UNCF is committed to getting more students like you to and through college.

2026-2027 The RADM (ret.) Jeffrey A. & Linda J. Cook Scholarship

The RADM (ret.) Jeffrey A. & Linda J. Cook Scholarship is a need-based, recurring scholarship for active-duty, retired U.S. military veterans, or their dependents who are enrolled full time and pursuing undergraduate STEM degrees at an accredited HBCU. Recipients will receive a renewable award of up to $4,250 to support them in obtaining their undergraduate degree.

This scholarship is in honor of CPO Arthur A. Cook and Capt. Delbert E. Colwell, the fathers of the Grantors who served honorably during WWII.

Multiplex Platforms to Assess Indicators of Micronutrient Status, Inflammation and Infectious Disease

The Challenge

Although combined immunological measurement of several micronutrient biomarkers has been demonstrated, current methods still have important limitations. These include heterogeneity in the composition of standards and controls; inconsistent batch-to-batch performance of analyte-binding molecules; variable reactivity for some analytes, especially soluble transferrin receptor (sTfR); and a functional analytical range that is too narrow to cover the physiological values of some analytes, such as CRP. It would also be valuable to add bioindicators for vitamins B1, B2, B9 and B12, which may require binding molecules that recognize metabolites or proteins associated with deficiency, a specific vitamer (plasma methyl-tetrahydrofolate without reacting with folic acid), comparable reactivity across vitamers (several folate forms in red blood cells), or a specific carrier-protein form (holo-transcobalamin rather than apo-transcobalamin or haptocorrin for vitamin B12).

The improved assays must combine high analytical specificity, sensitivity and robustness with a functional analytical range matched to the physiological values expected in the target populations (women of reproductive age, including during pregnancy and lactation, preschool-age children and older adults). Assays must remain low-cost (no more than US$20 for all analytes measured in duplicate) and require very small sample volumes, preferably less than 10 µL of plasma or serum). The tests are intended for population surveillance rather than local clinical (point-of-care) use. They should be designed to run many samples in a single batch in a small number of national or regional reference laboratories. The goal is to reduce dependence on expensive, infrequent population surveys and on export of samples to specialized laboratories in high-income settings.

This challenge is structured around two alternatives, a minimum-scope approach and an optimistic-scope approach. Targets are aligned with the candidate Target Product Profile for this platform, and applicants will be held to the relevant performance, cost and instrument targets.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5413 - Comparison of PFAS Contributions to Agricultural Systems

Grant Information

• Report per- and polyfluoroalkyl substance (PFAS) concentrations from a variety of agricultural inputs, including animal manures, fertilizers, pesticides, composts, soil amendments, seed coatings, and biosolids-based products.
• Compare the impact of the various agricultural inputs on PFAS concentration in the soil profile over varying timeframes.
• Evaluate the fate and transport of different inputs to PFAS contributions in agricultural systems at field-scale.
• Determine the relative contributions from biosolids-based products and other inputs to help develop and prioritize risk management strategies.

Mission

To empower worthy nonprofits by providing critically needed, unrestricted funding that helps them fulfill their missions with confidence and sustainability.

How We Serve Nonprofits

AmFund partners with nearly 800 organizations annually—supporting causes related to health, education, the arts, human services, animal welfare, and more. We’re known for our:

• Signature silent and live auctions featuring once-in-a-lifetime travel experiences.
• National reach with personalized service at events in all 50 states.
• Comprehensive marketing toolkits, onsite staff support, and beautifully displayed materials
• No-cost platform development for virtual and hybrid fundraising
• In-house travel specialists who provide custom planning, extensions, insurance, and 24/7 emergency support.
• Ongoing educational resources, grants, and consulting support for nonprofit development.

Request Support

Our model is built on relationship, trust, and results. Every trip sold, every service provided, and every donor interaction is designed to maximize your fundraising impact—without adding burden to your team.

The Gabriella Miller Kids First Pediatric Research Program invites applications for whole genome sequencing of pediatric cohorts. This initiative aims to explore the genetic basis of childhood cancers and congenital anomalies, enhancing our understanding of their etiology. Researchers are encouraged to propose sequencing methods, including whole genome and exome sequencing, to investigate genetic contributions and associations with cancer risk. The resulting data will be integrated into the Kids First Data Resource for broader research collaboration.

Generally the Community Foundation's scholarships are awarded to applicants who have high financial need. Applicants with household income exceeding $100,000 are less likely to be awarded, but applying will allow you to be considered for targeted scholarships.

Llewellyn L. Cayvan String Instrument Scholarship

Open to students studying music with concentration in viola, violin, violincello, or bass viol.

U.S. Small Business Administration

SBA works to ignite change and spark action so small businesses can confidently start, grow, expand, or recover. Created in 1953, the U.S. Small Business Administration (SBA) continues to help small business owners and entrepreneurs pursue the American dream. SBA is the only cabinet-level federal agency fully dedicated to small business and provides counseling, capital, and contracting expertise as the nation’s only go-to resource and voice for small businesses.

Manufacturing grants

SBA provides grants to help empower small manufacturers.

Empower To Grow (E2G) Manufacturing in America Grant

The goal of this grant is to provide workforce development in key manufacturing industries, such as timber, energy, aluminum, steel, digital, and automotive.

SBA is looking for organizations that will provide technical proficiency and essential skills, including operating machinery, quality control, welding, utilizing industrial software, and workplace safety. 

The Hypercholesterolemia Grant by the Patient Advocate Foundation offers financial assistance to individuals diagnosed with hypercholesterolemia, helping cover out-of-pocket healthcare costs such as medication copays and insurance premiums. This nonprofit aims to improve patient access to necessary care while supporting over 3.8 million patients since its inception. Eligible applicants must have health insurance and meet specific income requirements to receive assistance in managing their healthcare expenses effectively.

Hutsell, Alan Scholarship Fund

For a high school senior from Central Noble, East Noble, Wawasee, West Noble or homeschool (homeschooled student must live in Noble County) who will be pursuing advanced education in emergency services involving fire, police, criminal justice and/or EMS.

Awards Per Year:

• 1 scholarship

Applicant High School:

• Central Noble, East Noble, Homeschooled, Wawasee, West Noble

Colleges:

• Any accredited college or university

Areas of Study:

• Criminal Justice, Emergency Medical Services, Emergency Services, Emergency services involving fire, police, criminal justice and/or EMS.

The Behavioral Health Integration Initiative aims to enhance the health of American Indian and Alaska Native individuals by expanding access to integrated behavioral health care. It supports Tribal and Urban Indian Organization health systems in providing culturally responsive and trauma-informed services. The initiative focuses on improving care coordination, promoting early identification of mental health issues, and integrating various health services to improve overall health outcomes and quality of life for AI/AN communities.

The Les Paul Foundation Grant supports innovative music education and medical research related to hearing loss. Eligible organizations must be U.S.-based public charities under 501(c)(3) and avoid religious, political, labor, or business affiliations. The foundation prioritizes projects that enhance music production, performance, and STEM/STEAM initiatives, particularly those benefiting individuals in challenging situations. Proposals must detail how they will share Les Paul's legacy in their work.

Our Mission

The Sundance Institute is a nonprofit organization dedicated to the discovery and development of independent artists and audiences. Through its programs, the Institute seeks to discover, support, and inspire independent film and media artists from the United States and around the world, and to introduce audiences to their new work.

Sally Menke Editing Fellowship

Description of Fellowship

The Sally Menke Editing Fellowship will include the following elements:

• Two editing mentors; collaboration with Sundance Institute staff to identify the mentors who will be available from July 2026 through May 2027. You will engage in monthly meetings with one or both of the mentors for advice on the editing process and potential opportunities for career development. When appropriate, there might be a key moment to observe mentors at work during an essential part of their process.

• Invitation to join the American Cinema Editors as an associate member. Benefits include receiving the ACE CinemaEditor Magazine, invitations to events, and screeners, with the opportunity to vote for the Feature Film Best Editing categories as part of the ACE Awards.

• Invitations to join periodic informal gatherings of the cohort of Menke fellows.

• Invitation to join the Art of Editing event at the 2027 Sundance Film Festival, where the annual Menke fellow is announced.

• Participation as an editor for two of the directing fellows at the 2026 Sundance Directors Lab (fellow must be available to attend in person at the Stanley Hotel in Estes Park, Colorado, anticipated dates June 10–23, 2026).

The Isabelle Rowe Nursing Scholarship supports non-traditional students aged 21 and older from the Fox Valley and Waupaca areas pursuing nursing degrees. Established in 2007 by Julian Rowe in honor of his wife, Isabelle, this fund provides non-renewable scholarships of $2,000 for 4-year colleges and $1,000 for 2-year institutions. Applicants must maintain a minimum GPA of 2.5, have work experience in healthcare, and demonstrate financial need, with opportunities to reapply annually.