Best Large Grants for Nonprofit Organizations in Indiana

The 'Repurposing Research for Chicago - Track 1 – Health Equity' grant, offered by Cures Within Reach, aims to fund clinical repurposing trials addressing health disparities among underrepresented populations. With a budget of up to $100,000, it encourages trials led by underrepresented researchers or focusing on women's health. The initiative seeks to enhance the quality of life in the Chicagoland area through effective and innovative medical solutions, fostering collaboration across diverse stakeholder groups.

The IUSE: Innovation in Two-Year College STEM Education (ITYC) program, funded by the National Science Foundation (NSF), aims to enhance STEM education at two-year colleges. This initiative encourages innovative projects that promote student success in foundational STEM courses. Eligible institutions can request up to $500,000 for three years, with an extra $100,000 for those without NSF funding in the last five years, facilitating a total budget of $600,000 for impactful educational projects.

English Language Learning Foundation Incorporated

The English Learning Foundation, Inc. is a non-profit 501(c)(3) organization incorporated in 2006 to assist English language learners. The mission of the ELL Foundation is to help English learners to become successful in their academic lives while honoring their cultural identities.

Our vision is to assist English learners in the Greater Cincinnati area so that students:

• Appreciate and are proud of their cultural identities;
• Receive the needed support service for their education;
• Graduate from high school and succeed in college;
• And serve their communities as role models.

ELL Foundation’s College Emergency Grant

The College Emergency Grant Program provides emergency assistance of up to $500 for Greater Cincinnati college/ university EL students who are experiencing temporary financial emergencies. The focus areas for the grants include: 

• Student food insecurity (meal plans are eligible)
• Student housing insecurity (student housing is eligible)
• Student transportation barriers (bus passes are eligible)
  • Note that all assistance will be disbursed to the University, and not the student.

Due to funding availability, grantees can only receive one emergency grant per academic year. The ELL Foundation will accept emergency grant applications at any time, but applications will be reviewed on a quarterly basis. 

The CFSI Education Fund Scholarship, offered by the Community Foundation of Southern Indiana, awards multiple $2,000 non-renewable scholarships to students over 25 who have some college experience but no degree. This program aims to support those returning to complete their post-secondary education, including vocational training. By empowering individuals from Clark and Floyd counties, the scholarship fosters educational advancement and community growth, reflecting the foundation's commitment to enriching lives through learning.

Building a global community of creative problem solvers, effective collaborators, and empathetic individuals through theatre

Our Mission and Goals

The Educational Theatre Foundation (ETF) is the philanthropic arm of the Educational Theatre Association (EdTA).

ETF advances the field of educational theatre by broadening representation and increasing access for all. ETF’s programs aim to support students, educators and the field at large by realizing three strategic goals:

• Subsidizing new, emerging, and underserved student theatre programs;
• Creating paths for theatre educators to develop new skills; and
• Commissioning research to showcase the value of a theatre education.

Grants for Educators & Theatre Programs

A core piece of the Educational Theatre Foundation’s work is supporting theatre educators and theatre programs directly. We do this through a series of production and educator grants available to both members of EdTA as well as non-members.

For EdTA Members

Production Grants are offered in collaboration with the rights holders for specific plays and musicals or for initiative-based productions that build community.

Production Grants

Show-specific financial assistance for educational theatre programs

Music Theatre International: Heart of Rock and Roll "The Power of Love" Grant

Heart of Rock and Roll features a book by Jonathan Abrams and music and lyrics by Huey Lewis and his pop-rock band, Huey Lewis and the News, with new orchestrations of their music by Brian Usifer.

Selected schools will host intergenerational community events or outreach programs of their own design — because just as Huey Lewis’s music has always brought people together, school theatre has the power to do the same.

The Marlene and Spencer Hays Foundation Grants support tax-exempt organizations working to enhance lives through arts, healthcare, education, and youth programs. The foundation requires a Letter of Intent (LOI) from all applicants, emphasizing its mission to select grant recipients who align with its values. Grants are not available for political purposes, endowment campaigns, or organizations that discriminate based on race, gender, or religion. This framework ensures a focused impact on community betterment.

The ASTRO-AstraZeneca SCLC Therapy Challenge RFP aims to enhance research on limited-stage small cell lung cancer (LS-SCLC) through innovative combination therapies, particularly integrating immunotherapy with advanced radiation techniques. Proposals are encouraged to explore various aspects, including care patterns, treatment workflows, prognostic biomarkers, and toxicity management. The target budget for projects ranges from $175,000 to $375,000, with consideration given to higher requests based on scientific merit, fostering significant advancements in radiation oncology.

The Puffin Foundation's Annual Artist Grant Program focuses on supporting artists and organizations that are often marginalized. In even years, proposals are accepted in fine arts, music, and photography. With a maximum grant size of $3,500, it aims to empower individuals and groups with limited resources to flourish creatively. This initiative reflects the Foundation's commitment to ensuring diverse artistic expressions thrive in society. Applicants must be U.S. citizens or residents, and only one proposal is permitted per year.

31Heroes

On August 6, 2011, a tragedy shook the military community and Americans everywhere. In a single instance, America lost 30 military service members, many of whom were members of the Navy SEAL community—and one military K9– when a CH-47 Chinook helicopter, call sign Extortion 17, was downed in Afghanistan.

Established to honor the 31 Americans killed in action on August 6, 2011, 31Heroes serves to impact the lives of our nation’s heroes and their families, while remembering the fallen, through athletic endeavors and competitive fundraising events.

Our Mission: The mission of 31Heroes is to raise money and awareness through social and athletic events to support the families of Extortion 17 and honor their legacy by funding treatment for Veterans suffering from mental health issues.

Our Focus

Our goal is to create opportunities for the families of Extortion 17 to create healthier lifestyles and to provide financial relief in times of need. We consider it our responsibility to make a positive impact in the lives of each family. Whether through grants we provide, or through partnering with other non-profit organizations that offer programs or services that we do not, we are devoted to the families and creating a legacy the men of Extortion 17 would be proud of.

Guidelines

• Individual limits will not exceed $3750 annually
• Family Grants range from $750 to the maximum range of $1500
• Family members must submit an online application for consideration
• Applications may be submitted at any time during this funding cycle
• Priority and funding will be based on the Primary Next of Kin list

Lifestyle Grants

Lifestyle Grants are aimed at improving health and lifestyle via physical fitness, nutrition, holistic treatment, etc. Limit for this grant is $1500

The F26AS00023 FY2026 Prescott Marine Mammal Rescue and Response Grant Program offers crucial financial support for marine mammal rescue efforts. This initiative aims to assist eligible participants in the recovery and treatment of stranded marine mammals, provide emergency response to stranding events, and enhance scientific research on marine mammal health. The program prioritizes applications that effectively address species-specific needs and bolster the capacity of stranding networks, ensuring the welfare of marine wildlife under the management of the U.S. Fish and Wildlife Service.

The Sonny Greenwood Calzaretta Scholarship, offered by the Pride Foundation, supports LGBTQ+ students from rural communities facing isolation and limited access to resources. Established to honor the legacy of Brian M. Day, this scholarship aims to empower students pursuing post-secondary education while addressing systemic barriers. It prioritizes those demonstrating a commitment to justice and who have experienced challenges such as family rejection or economic hardship. The scholarship is part of a broader initiative to uplift diverse voices within the LGBTQ+ community.

Pledge the Pink Foundation is dedicated to providing essential funding for breast cancer services, including free mammograms, medical assistance, and outreach programs. By bypassing bureaucratic barriers, the foundation ensures that those most in need receive critical care. However, grant funds cannot be allocated for event sponsorships or to cover salaries and overhead expenses, ensuring that donations directly impact patient care and support.

The Developing Talent Grant Program, established by the Don Wood Foundation, aims to empower young individuals in northeast Indiana by enhancing access to high-quality STEAM education and career pathways. By fostering partnerships among schools, nonprofits, and industry, the program promotes experiential learning and essential skills like leadership and adaptability. This initiative not only equips students with the necessary tools for future success but also strengthens the local workforce, ensuring a sustainable impact on the community.

The NIDCD Early Career Research (ECR) Award (R21) supports new scientists establishing independent research careers in areas related to hearing, balance, smell, taste, voice, speech, or language. This grant encourages innovative projects such as secondary data analysis, small research initiatives, and technology development, aiming to generate preliminary data for future R01 applications. All applications must be submitted by 5:00 PM local time of the applicant organization.

Batten Disease Support, Research, and Advocacy (BDSRA) Foundation

BDSRA is dedicated to funding research for treatments and cures, providing family support services, advancing education, raising awareness, and advocating for legislative action. Founded in 1987, by parents seeking to build a network for those diagnosed with Batten disease, BDSRA is now the largest support and research organization dedicated to Batten disease in North America. BDSRA believes that to effectively unravel the mysteries of Batten disease, the worlds of medical science, research, and families must work together toward a common goal: discover treatments and cures while assuring a better quality of life for those living with the disease.

Batten Family Help Grant

The BDSRA Foundation is committed to supporting families of all CLN types in all aspects of their fight against Batten, including the financial challenges they face. BDSRA understands that families in our community caring for people with Batten disease are often faced with financial challenges that further interfere with their well-being.

We offer grants to help cover the costs associated with battling Batten disease, such as emergency travel, loss of employment, hospital bills, and other challenges our families might face.

The Aim High Grant Program, funded by the New York Life Foundation, offers 15 two-year grants of $100,000 each to support out-of-school time programs that assist middle school students in their transition to high school. This initiative addresses chronic absenteeism and promotes educational attainment in low-income communities, enhancing the cognitive, social, and emotional development of youth. By fostering skills necessary for academic success, the program aims to create brighter futures for participants.

The NIH is inviting applications for interventions aimed at enhancing cancer screening and preventive services in underserved populations. This initiative focuses on addressing barriers to healthcare access and promoting timely follow-up on abnormal findings. Collaborations with community partners are encouraged to foster effective outreach. The program particularly seeks to engage patients, clinicians, and healthcare settings in improving health equity and outcomes in cancer prevention.

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Grants & Fellowships

Fellowships

The Mensa Foundation Fellowship program empowers exceptional individuals committed to advancing the application of intelligence in their respective fields.

Details

Our current fellowship, the Gifted Education Fellowship, is designed to empower educators pursuing graduate studies in gifted education or closely related fields, enabling them to make a transformative impact in their classrooms and communities. The fellowship supports both doctoral and non-doctoral students, with awards and renewal terms tailored to each track.

The Mary Kay Ash Foundation Domestic Violence Shelter Grant Program supports shelters across the U.S. that provide essential services to women and children escaping abusive situations. Established in 2000, this grant aims to uphold the mission of eradicating domestic violence through financial assistance to dedicated organizations. Eligibility is limited to shelters recognized by state domestic violence coalitions, while those funded in the previous cycle are ineligible. Join the fight against domestic violence by applying for this vital support.

The Bertin Family Foundation Grants support 501(c)(3) public charities that align with the foundation's mission of community strengthening and compassion. Grant requests are accepted annually from July 1 to August 31, focusing on program or project support rather than general endowment. The foundation values measurable outcomes and responsible stewardship, and gives preference to organizations with Gold or Platinum status on Candid.

The SMART Scholarship-for-Service Program, managed by the Department of War, aims to enhance the U.S. military's technical workforce by offering competitive scholarships for STEM degrees. With a funding cap of $1.3 billion over ten years, the program prepares scholars for critical roles in national defense, ensuring a pipeline of skilled professionals. Since its inception in 2005, over 8,000 scholarships have been awarded, fostering a strong connection between education and service in defense-related fields.

Society of Hospital Medicine (SHM)

The Society of Hospital Medicine (SHM) is dedicated to promoting high-value care and achieving optimal outcomes for acutely ill patients. As part of this mission, SHM seeks to address inequities in acute patient care and contribute to a greater dialogue on this important issue. As the home for hospitalists, SHM activates and engages our community to

• Advocate for our specialty, our members, and the diverse patients we serve.
• Promote high-value care and optimal outcomes for acutely ill patients.
• Meet the evolving educational needs of a dynamic specialty.
• Cultivate an inclusive community for hospitalists and support career growth and wellbeing.
• Advance the research and innovation of healthcare delivery, quality, safety, and experience across the care continuum.

SHM’s Excellence in Teamwork Award

This award is presented in recognition of exemplary quality improvement initiatives in hospital medicine that engage the full patient care team. The award is intended to highlight outstanding team approaches to implementing interventions that improve patient care and safety but is particularly interested in projects related to the core competencies in hospital medicine and SHM’s quality improvement resource rooms. 

Recipients of the Excellence in Teamwork in Quality Improvement Award receive recognition at SHM Converge 2026 and complimentary registration for up to 4 team members.

The Food Access and Retail Expansion (FARE) Fund Grant, part of America’s Healthy Food Financing Initiative, aims to enhance access to nutritious food in underserved regions. With a budget of $60 million over five years, the initiative supports innovative fresh food retail projects, offering grants and loans to address barriers in food access. This funding is crucial for catalyzing sustainable food enterprises and improving local food systems, ultimately fostering healthier communities.

The RMD Music Scholarship, managed by the Northern Piedmont Community Foundation, offers a $12,000 renewable scholarship for graduating seniors from Fauquier or Rappahannock County public schools pursuing a music degree at an accredited institution. Eligible students must demonstrate leadership and motivation, and must audition in their senior year while providing proof of acceptance into a university music program. Renewal depends on maintaining a minimum GPA of 2.7.

The Rodger H. Baker Scholarship, managed by the Northern Piedmont Community Foundation, supports graduating seniors from Fauquier County Public Schools pursuing health careers at 2- or 4-year institutions. Ideal candidates excel academically, demonstrate leadership, have community service experience, and show commitment to their field of study. Financial need is considered, with preference given to nursing students, although all health disciplines are welcome. This scholarship reflects the Foundation's dedication to enhancing local educational opportunities.

CHEJ Small Grants Program

The Small Grants Program has officially relaunched. Applications are now open.The Center for Health, Environment & Justice’s (CHEJ) Small Grants Program is for grassroots groups working on environmental health and justice issues related to the presence of “toxics” (toxic chemicals or hazardous substances) in their immediate communities. CHEJ prioritizes community-based organizations aiming to have local, state and regional impact through their own strategies and actions.

Scott Cornelius Memorial Scholarship (Piedmont)

To honor the memory of Scott Cornelius by supporting students pursuing careers in sales, marketing, insurance or related business fields who demonstrate leadership and integrity.