Best Unrestricted Grants for Nonprofits in Indiana

The DoW Spinal Cord Injury Translational Research Award supports innovative research to transform promising spinal cord injury findings into clinical applications. It features an Early-Career Partnership Option, requiring at least one early-career principal investigator. Collaborations with SCI community partners are essential for providing guidance throughout the project. This funding opportunity aims to enhance the effectiveness of spinal cord injury interventions and improve patient outcomes.

Gray for Glioblastoma Society

A 501 (c) 3 created to raise awareness for and funds to support Glioblastoma Multiforme research by accepting donations and donating to cancer care and research facilities. Our organization has gifted over $275,000 to support GBM research projects at renowned cancer centers including The Ty Miller Lab at Case Western Reserve University, Dana Farber Cancer Institute, Children’s Hospital LA/Saban Research Institute and The Preston Robert Tisch Brain Tumor Center at Duke. We accomplish this while simultaneously creating a hopeful and positive space and providing resources and a space of community through our social media and events.

Gray for Glioblastoma Grant

Gray for Glioblastoma Society (GFG) is dedicated to funding projects that advance glioblastoma (GBM) research and move the needle forward in care and quality of life. We invite proposals that align with our mission and demonstrate meaningful impact in the GBM space.

The FY26 Spinal Cord Injury Research Program Clinical Translation Research Award funds innovative clinical research aimed at bridging the gap to larger clinical trials. It focuses on accelerating the application of new techniques and improving patient outcomes through effective diagnosis and rehabilitation strategies. Key features include an Early-Career Partnership Option for principal investigators and a requirement for community partner involvement, ensuring collaborative research that meets real-world needs.

The FY26 Spinal Cord Injury Research Program Clinical Trial Award supports innovative clinical trials aimed at significantly improving spinal cord injury treatment. This funding opportunity encourages collaboration by allowing two Principal Investigators, including an early-career investigator, to drive the research forward. Applicants must partner with at least two SCI community members, ensuring that the project is informed by lived experiences and community needs throughout its development and implementation.

The Small Instruments and Modern Equipment program invites shared-use biomedical research facilities to apply for funding to purchase small instruments or scientific equipment. These resources, which may include core facilities and biorepositories, aim to enhance operational efficiency and support the use of innovative technologies. Funding is specifically targeted for instruments that produce outputs beyond traditional digital data, excluding highly specialized or building-level infrastructure equipment.

The Regional Excellence for Access to Comprehensive Care for Hemophilia Networks (REACH Networks) aims to enhance access to coordinated, evidence-based care for individuals with hemophilia and related disorders. This initiative will broaden access to comprehensive care, implement quality improvement projects, and provide ongoing training and education for Hemophilia Treatment Center staff. The focus is on improving best practices for comprehensive, collaborative care, including effective lifespan transitions for patients.

The FY26 Spinal Cord Injury Research Program (SCIRP) Investigator-Initiated Research Award (IIRA) supports innovative research aimed at enhancing patient care and quality of life for individuals with spinal cord injuries. This award encourages collaboration, allowing an Early-Career Partnership Option for two Principal Investigators, where one must be an early-career investigator. Focused on impactful research from basic to translational science, this opportunity is crucial for advancing SCI knowledge and interventions.

The Larson-Veneklasen Outdoor Education Scholarship, established by Ken Larson and Diane Veneklasen, supports Tri-Cities residents pursuing outdoor educational experiences. Inspired by the Outward Bound philosophy, it aims to foster character development and self-discovery through adventure. Applicants can access multiple foundation scholarships with a single application. Required documents include transcripts and any additional materials specified for specific scholarships. Notably, financial need is not a priority, and high school seniors are not restricted from applying.

Carol J. Kenagy Nursing Education Scholarship

In memory of Carol J. Kenagy, RN and through the wonderful generosity of our donors, Silverton Health Foundation is able to offer continuing education scholarships for Legacy Silverton staff pursuing nursing degrees.

The Carol J. Kenagy Nursing Education Scholarships will be awarded on an annual basis.

All clinical programs are eligible and encouraged to apply.

Amount of Award:

• up to $5,000 annually 
• Number of Awards: 2-3

The BJA FY 2026 Edward Byrne Memorial Justice Assistance Grant (JAG) Program offers formula funding to support local governments in enhancing public safety. This grant aids in hiring personnel, purchasing essential equipment, and providing training and technical assistance to address crime and safety challenges. Applicants are encouraged to verify their eligibility for direct JAG funding from BJA before submitting their applications. The deadline for full applications is October 16, 2026, at 8:59 p.m. ET.

Dr. Sonny Rush Memorial Scholarship

Dr. Sonny Rush was a pioneering orthopedic surgeon and a kind friend to all his patients. He encouraged all students interested in healthcare to pursue their passion in the medical field. This scholarship was established by his family in his memory and is designed to help jumpstart a career in the healthcare field. 

Amount

• 1500

The Reeves Foundation supports research aimed at understanding and treating macular degeneration, a condition that has personally affected the founder's family. Established in 1997, the foundation allocates 50% of its grants to research and the other half to local charities in Columbus, Indiana. Nonprofit organizations exempt under IRS code 501(c)(3) are eligible to apply, but funds cannot be used for administrative costs. The foundation prioritizes equipment purchases and partnerships with other funding sources.

Dave Dupont Memorial Scholarship

The family remembers Dave as a very kind hearted, loving husband, father, and friend. He and his wife Sandi were married 35 years, and had 2 children Kyle and Danielle DuPont.

Dave loved to give back to his community, and attend as many fundraisers as he could. Dave would be proud to be able to give back to the kids in his community.

Community Foundation of Central Wisconsin

The Community Foundation of Central Wisconsin gives everyone the opportunity to make significant and lasting gifts to their community. We manage over 320 funds that enhance Portage and Waushara counties. Together with our generous donors, we create a strong culture of philanthropy in Central Wisconsin.

We are a tax-exempt, 501(c)(3) public charity founded in 1982 to provide scholarships and grants to organizations and projects that improve the quality of life in Portage and Waushara counties.

Scholarships

The Community Foundation proudly supports students in Portage and Waushara counties with over $325,000 in scholarships annually, thanks to the generosity of local individuals and families. Award amounts range from $500 to $40,000, opening doors to educational opportunities.

Whether you're a student seeking financial support or a donor looking to grow a scholarship fund, we invite you to explore available opportunities and learn how you can be involved.

Don & Mary Hamerski Memorial Scholarship Fund

Qualifications: Graduating High School seniors from a Central Wisconsin high school.

The FY26 Peer Reviewed Cancer Research Program's Idea Award promotes innovative, high-risk cancer research initiatives. It supports groundbreaking concepts that advance cancer knowledge, patient care, and treatment options within the Military Health System. Projects must demonstrate creativity and innovation, avoiding incremental advancements. Notably, the Early Career Investigator Option is available to foster the growth of promising new investigators early in their careers. This award aims to make significant contributions to cancer research for Service Members and Veterans.

The DoW Peer Reviewed Cancer Clinical Trial Award supports the rapid initiation of clinical trials aimed at significantly improving cancer treatment. Projects may range from small pilot studies to large-scale phase III trials, focusing on innovative products, drugs, or devices. This award mandates the inclusion of patient advocates and prohibits animal studies, ensuring that all preclinical work is completed prior to the award start date. Regulatory applications must be submitted if required for the proposed trials.

The FY26 Neurofibromatosis Research Program's Synergistic Idea Award supports innovative research on neurofibromatosis (NF) through collaborative efforts of two or three Principal Investigators (PIs). By leveraging their unique perspectives, these PIs will tackle significant questions in NF research. Applicants must provide relevant preliminary or published data to support their proposals, ensuring a strong foundation for impactful research outcomes.

The Placement and Coordination Program, administered by the Office of Refugee Resettlement, invites eligible organizations to enhance refugee resettlement services. By diversifying service providers, the program aims to strengthen the national resettlement framework. Key responsibilities include managing the Program of Initial Resettlement and Intensive Case Management for vulnerable refugees, ensuring comprehensive support from arrival through initial resettlement, and addressing barriers to self-sufficiency.

The Presbyterian Committee on the Self-Development of People Grant Program supports projects led by economically disadvantaged communities to combat poverty and injustice. By promoting justice, building stronger communities, and advocating for economic equity, this program empowers individuals and groups to address the root causes of their struggles. The initiative seeks sustainable solutions that respect the environment and reject violence, fostering long-term positive change in society.

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

Roger Testrake Memorial Scholarship

The Roger Testrake Memorial Scholarship benefits students residing in Ripley, NY who plan on continuing their education after high school and have a relative who has served in the military.

Roger Testrake was instrumental in building a monument in Ripley to honor all veterans. This scholarship was renamed to honor him for all his perseverance, dedication and hard work on behalf of the Ripley Veterans Roll of Honor Organization. 

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

Timothy Ryan Memorial Scholarship

The Timothy Ryan Memorial Scholarship Fund provides scholarships to students who exemplify characteristics exhibited by Timothy during his brief life: loving, caring, generous, family-oriented, genuine, sincere, and humorous.

The NIAID aims to enhance infectious disease research by supporting human microphysiologic systems (MPS) development. These in vitro platforms mimic human tissue functions, promoting drug and biological product development while reducing animal use. This initiative aligns with NIH’s commitment to innovative research practices and regulatory acceptance. By focusing on MPS in infectious disease contexts, NIAID seeks to streamline therapeutic advancements and establish robust human tissue models, addressing critical challenges in understanding and treating infections.

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

St. Joseph School Scholarship

The St. Joseph School Scholarship is awarded to a graduating senior who resides in northern Chautauqua County, and intends to pursue a career teaching children with special needs.

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

Rev. Clifford K. Cliver & Lucy Cliver Sumsky Scholarship

The Rev. Clifford K. Cliver & Lucy Cliver Sumsky Scholarship Fund acknowledges and supports Chautauqua County foster children by providing scholarships for continuing education.

The BRAIN Initiative seeks to develop innovative tools and approaches for neuroscience research, focusing on cell-specific and circuit-specific processes within the central nervous system. This initiative encourages projects that enhance our understanding of brain architecture and function through novel technologies for characterizing neural components and advancing methods for recording and modulating neural activity. Applications are invited to address significant challenges and promote transformative breakthroughs in neuroscience.

Mary O' Neill Mini Grant

Dr. Barbara O’Neill, an AFCPE member and Past President of AFCPE, has made a restricted donation to AFCPE in honor of her late mother, Mary O’Neill, a financially capable woman. The donation will support an annual $5,000 mini-grant for development and implementation of an innovative, high-impact financial educational nonprofit project. 

Winner is notified by October 1 and announced at AFCPE Symposium.

The TIP Office of the US Department of State invites applications for projects aimed at combating human trafficking, adhering to the Trafficking Victims Protection Act. This initiative prioritizes prosecuting traffickers, protecting victims, and preventing trafficking through strategies outlined in the National Security Strategy, executive orders, and the annual Trafficking in Persons Report, while aligning with America First Foreign Policy priorities.