Best Unrestricted Grants for Nonprofits in Indiana

The Fiscal Year 2026 Wildlife Crossings Pilot Program aims to enhance public safety by reducing wildlife-vehicle collisions and improving habitat connectivity for various species. With approximately $80 million available through cost reimbursable grants, this initiative supports eligible projects that address these critical environmental and safety concerns. The program may also distribute leftover funds from previous years, contingent on availability, fostering innovative solutions in wildlife management and transportation safety.

The CHEERS Open Period 1 invites white papers focused on enhancing operational medicine and support for Airmen and Guardians. Managed by the Air Force Research Laboratory and USAFSAM, this opportunity aims to address future demands in Aerospace Medicine, Occupational Health, and Public Health. Proposals should align with the objectives outlined in the Continuing Human Enabling, Enhancing, Restoring and Sustaining announcement. This initiative emphasizes innovative solutions to support the Department of Defense's mission.

The AES Hawaiʻi Foundation Grant supports communities near AES Hawaiʻi’s renewable energy projects, focusing on social justice, education, environmental stewardship, and community health. Preference is given to nonprofit organizations in these areas, but statewide entities may also apply. Successful projects should align with the Foundation’s impact pillars, demonstrate measurable community benefits, and address unmet needs, ensuring long-term positive effects on the local community.

The Turtle Trackers - Linda Zambelli Family Scholarship Fund, established in 2025 by the Turtle Trackers Board, honors Linda Zambelli's legacy through scholarships for students pursuing higher education in Marine Biology and Environmental Sciences. This initiative supports high school seniors from Beaufort and Jasper Counties, ensuring they have opportunities to excel academically while fostering a commitment to marine conservation. The fund is managed by the Community Foundation of the Lowcountry, which has invested over $125 million in local communities.

The Steel Dynamics Foundation Grant focuses on enhancing community quality of life and local economies by supporting 501(c)(3) nonprofit organizations. Priorities include higher education, economic development, and human services, particularly in communities where Steel Dynamics operates. Grants are awarded based on community impact, employee involvement, and organizational integrity. Applicants must demonstrate a strong ethical track record and effective community engagement to qualify for funding opportunities.

The Community Foundation of Muncie and Delaware County offers Community Grants aimed at enhancing the quality of life in Muncie and Delaware County, Indiana. This program supports initiatives in arts, culture, education, and community betterment, encouraging nonprofits to provide compelling cases for funding. Grants are awarded on a rolling basis to 501(c)(3) organizations and other public charities, focusing on projects that yield substantial benefits and foster long-term change for the community.

The Kenneth Rainin Foundation seeks to promote innovative research in Inflammatory Bowel Disease (IBD) by encouraging diverse perspectives from early career investigators and those underrepresented in science. The Innovator Awards do not require preliminary data and are evaluated based on the potential for innovation and scientific merit. Eligible researchers must hold advanced degrees and can apply for funding through their home institutions, fostering groundbreaking ideas that can transform IBD treatment and prevention.

The Thomas P. and Sondra D. Sheehan Charitable Foundation provides essential medical assistance to financially challenged families, focusing on children in need. The foundation prioritizes Hamilton County residents and offers support for durable medical equipment, therapy services, and short-term treatments. Applications for funding must meet specific medical guidelines and are reviewed annually. Families connected to nonprofit organizations or medical facilities have a better chance of receiving assistance, ensuring children can access necessary healthcare and improve their quality of life.

The Herman J. and Helen D. Wyngarden Memorial Scholarship, offered by the Grand Haven Area Community Foundation, supports students from Northern Ottawa County or local high schools. Established in memory of dedicated educators, this scholarship encourages academic advancement beyond high school. Eligible applicants should provide transcripts and relevant documents, with preference given to those pursuing economics or medicine. This competitive scholarship aims to honor the legacy of the Wyngardens while empowering future leaders.

The Good Deeds Grant, offered by the Community Foundation of Wabash County, provides small to mid-sized grants (up to $5,000) to nonprofit organizations addressing basic needs and enrichment for Wabash County citizens. Eligible organizations include those defined as tax-exempt under 501(c)(3) or those with charitable causes. Grants prioritize projects that meet human needs, create opportunities, and enhance organizational capacity for serving limited-resource communities.

The Sparkplug Foundation Grant supports innovative projects from early-stage organizations and established non-profits in education, community organizing, and music. The foundation emphasizes community-led initiatives that address systemic injustices and engage marginalized populations. Grants are available for one year and prioritize projects with small budgets that lack extensive funding sources. The foundation encourages applications from diverse communities, particularly those led by Black, Indigenous, People of Color, and LGBTQ individuals, fostering equitable access to resources.

The Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs) program invites applications to enhance communication and collaboration among researchers in digestive and liver diseases. Funded by the NIDDK, DDRCCs focus on shared resources that foster productivity and innovative research ideas. Each center must revolve around a central theme aligned with the NIDDK's mission, ensuring effective research support while avoiding overlap with other NIH Institutes' funding areas.

The Ray and Sue Barrett Scholarship, offered by the Grand Haven Area Community Foundation, supports high school seniors in the Tri-Cities pursuing higher education in law, criminal justice, mental health, social work, or psychology. Established in honor of Ray and Sue Barrett, who valued education and mental health, this scholarship considers financial need and requires a minimum 2.5 GPA. Applicants must submit transcripts and relevant documents to qualify.

About

Created by the community for the good of the community, the GLCCF is here to turn problems into opportunities through strategic grant making and initiatives created to address our region’s most pressing needs. We work with you to identify your charitable goals, and we ensure that they are carried out efficiently.

Work with us to make the kind of impact you want to see in your community. Let us take on the financial complexities and paperwork, while you focus on the important things like fostering good works throughout our community.

When you give to the Greater Lake City Community Foundation, you are making an investment that will benefit the community, now and in the future.

GLCCF Schreck Family Soccer Scholarship

To award annually a scholarship to a qualified applicant who intends to pursue education toward a 4-year college degree.

The EPSCoR Research Infrastructure Improvement (RII): EPSCoR Research Fellows program, funded by the National Science Foundation (NSF), aims to enhance research capacity and workforce development in STEM. This initiative fosters collaborations between underrepresented researchers and leading institutions, providing essential resources and support. With two tracks available—one focusing on NSF and the other on NASA—this program uniquely positions Fellows to leverage transformative research experiences and contribute to sustainable advancements in their respective fields.

J.B. Hunt Transport Services offers financial support for various community projects through its Company Giving program. Focused on four key areas—Health Care, Veterans' Support, Education, and Crisis Management—this initiative aims to enhance the well-being of local communities. Eligible applicants include 501(c)(3) organizations, schools, and civic groups, while organizations that primarily benefit their members or have high management overhead may be excluded. The program underscores J.B. Hunt's commitment to corporate social responsibility.

This funding opportunity from the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to advance mechanistic research on metal exposure and its effects on human health. Studies should focus on biological processes altered by metals, including their absorption, transport, and immune interactions. Innovative methodologies and human biospecimens are encouraged to explore how metals might impact immune homeostasis and cross biological barriers, providing insights into health risks associated with metal exposure.

The Environmental Grantmaking Program at the Educational Foundation of America (EFA) aims to support projects that facilitate a transition to a net-zero electricity system. Focused on reducing greenhouse gas emissions, the program emphasizes initiatives that enhance access to affordable clean energy, accelerate regional transitions, and strengthen financial investment in electric utilities. Eligible applicants include 501(c)3 public charities, academic institutions, and government entities committed to sustainable energy solutions.

T32 Postdoctoral Training Awards in Translational Research

The Indiana Clinical and Translational Sciences Institute (CTSI) T32 Postdoctoral Training Awards, funded in part by NCATS, are designed to provide promising postdoctoral fellows with the opportunity to be mentored in research-intensive multi-disciplinary settings toward the goal of developing careers across the spectrum of translational research.

The emphasis of the Indiana CTSI postdoctoral training awards in translational research is to move findings from basic laboratory and pre-clinical research (referred to as T1 research) toward the development of new treatment options or interventions or clinical trials (referred to as T2 research) to eventual dissemination or clinical implementation (referred to as T3 research) to studying population health outcomes and health metrics (referred to as T4 research). The phases of translational research may not necessarily be linear and can jump steps depending on the research project and the starting point. The goal of the Indiana CTSI is to make awards at all of these stages.

Funding for all postdoctoral training awards is for up to two years (with the 2nd year of funding contingent upon review and demonstration of satisfactory progress). Benefits include salary support as well as health insurance and research training related expenses.

The Sidney R. Baer, Jr. Foundation focuses on improving the lives of individuals with schizophrenia and bipolar disorder through education grants. By funding programs that enhance educational opportunities, the foundation aims to reduce isolation and promote understanding. Grants are awarded to qualified organizations that prioritize mental health initiatives, ensuring that those affected have access to the resources and support necessary for a better quality of life. The foundation's mission is rooted in the belief that education can be transformative for those facing mental health challenges.

The AAO-HNSF Percy Memorial Research Award offers $25,000 for one year to support innovative research projects in otolaryngology-head and neck surgery. This grant aims to fund projects with clinical significance, encouraging the development of new long-term research initiatives. Applicants must submit a detailed budget and secure letters of support from their Department Chair and key personnel involved in the project. Funds cannot cover salaries or purchase equipment exceeding $500.

About Us

We are a philanthropic organization committed to catalyzing the impact of social entrepreneurs who are expanding access and opportunity in America. 

At New Profit, we partner with social innovators, philanthropists, and other impact leaders who are creating a more inclusive and prosperous America. We invest in and support leaders and organizations that are transforming our education, economic, and democratic systems. And we are guided by the belief that those who are most proximate to the communities we serve are the best positioned to develop effective and sustainable solutions.

We seek and support leaders and organizations with scalable solutions that match the size of the problems we face and expansive visions that match the scale of our ambitions for America.

Connected Futures Cohort Grant

New Profit is launching Connected Futures, a Catalyze cohort for organizations that bridge divides and bring people together to solve problems collectively. Submit a Discovery Form to signal your interest and to be considered to submit an application for this funding cycle. 

New Profit’s Catalyze cohorts support innovative social impact organizations expanding access and opportunity in America. This model brings together cohorts of organizations with similar focus areas and stages, providing each with a one-year $100,000 unrestricted grant, a $10,000 grant for leadership development, and strategic advisory support.

Social Entrepreneurs* participate in a year-long cohort experience designed to build community, facilitate peer learning, and provide capacity-building support, including workshops on topics such as board development, fundraising, scenario planning, and storytelling. 

About Connected Futures

Connected Futures is a new Catalyze cohort for organizations that help people move across active divides to take action toward common goals. We are looking for organizations that build trust, strengthen collaboration, and create ways for people to act together when mistrust, polarization, exclusion, or disconnection would otherwise keep them apart and prevent them from solving problems together.

These organizations may work in the health, economic mobility, democracy, and/or education sectors. What connects them is not a single issue area, but a common approach to bridgebuilding: creating the relationships, skills, and structures people need to work together toward positive change.

Catalyze cohorts are at their best when cohort members are fully engaged. The Social Entrepreneurs that lead selected organizations are expected to participate in the Catalyze support model and peer learning community in the following ways:

• Social Entrepreneurs attend three in-person convenings, each of which are held over 3-4 days in cities across the United States. Convening dates for this cohort will be shared with organizations invited to complete a full application.
• Social Entrepreneurs attend three virtual learning sessions, each lasting 2-3 hours. Webinar dates for this cohort will be shared with organizations invited to complete a full application.
• Social Entrepreneurs engage with the New Profit team via 1:1 strategic advising, including a minimum of six virtual sessions over the yearlong cohort.
• Entrepreneurs receive a $10,000 stipend specifically to support their own leadership development goals.
• Programming requires a commitment of 6-8 hours per month on average. New Profit covers the cost of travel, accommodation, and meal expenses for each in-person convening.

The Tribal Solar Accelerator Fund (TSAF) empowers tribal communities across the U.S. by promoting renewable energy projects and workforce development. Launched by GRID Alternatives, TSAF provides critical funding for solar initiatives, enhancing energy sovereignty and resilience. Since its inception, TSAF has integrated community participation into its projects, ensuring that tribes can access sustainable energy solutions. By prioritizing education and equity, TSAF supports a transition to a clean energy economy, aiming for a sustainable future for generations to come.

The AAO-HNSF/ANS Herbert Silverstein Otology/Neurotology Research Award supports innovative clinical or basic science research focused on auditory and vestibular diseases. Established by Herbert Silverstein, MD, this award aims to assist young academic investigators in launching new projects. Since 2000, it has funded seven grants totaling $175,000, emphasizing projects with clear clinical relevance and potential for future funding. Applicants must demonstrate commitment to research and secure institutional support, with a priority for junior faculty and fellows.

The CAPTRUST Community Foundation provides Crisis Grants to support nonprofit organizations aiding families impacted by natural disasters or emergencies. By dedicating over 10% of its annual budget for crisis assistance, the foundation ensures that funds directly benefit those in need. Grants can be requested up to $5,000 to help rebuild lives during challenging times, reflecting the foundation's commitment to integrity and support for children and families in crisis.

The Hunger to Health Collaboratory (H2HC) 2025 Prizes for Innovation aim to enhance health equity for youth through innovative funding in three categories: Food and Nutrition Policy, Nutrition Education & School Food, and Indigenous Food Justice. Supported by Newman’s Own Foundation, these prizes include $100K grants for policy work and $25K grants for education and justice initiatives. Winners will participate in the H2HC Fall Summit in Boston, fostering collaborative solutions to food challenges.

The VIA Art Fund provides Artistic Production Grants to support innovative artistic commissions for public spaces. These grants, ranging from $25,000 to $100,000, are awarded twice a year to artists and organizations that exemplify artistic excellence and public engagement. Projects must have a confirmed exhibition venue, ensuring artworks reach diverse audiences and foster meaningful community experiences beyond traditional gallery settings.