Best Grants for 501(c)(3) in Iowa

The Big Ten Academic Alliance Smithsonian Fellowship offers unique research opportunities for graduate students from member universities. Eligible candidates can conduct research at the Smithsonian in diverse fields such as anthropology, ecology, and history of science. The fellowship provides a stipend of $45,000 per year, with additional research allowances, and supports both U.S. and international students. This initiative fosters collaboration among leading academic institutions to advance knowledge and innovation.

The ALDI Community Gift Card Program provides financial support ranging from $100 to $1,000 to eligible nonprofits and schools that focus on after-school and out-of-school youth programs, as well as food banks. This initiative aims to empower organizations dedicated to child development and combating food insecurity. By applying, you can gain access to essential resources to further your mission and make a positive impact in your community.

The Norman E. Borlaug International Agricultural Science and Technology Fellowship Program FY2026, funded by the USDA's Foreign Agricultural Service, aims to enhance agricultural research and education collaborations between U.S. institutions and researchers from emerging markets. This initiative not only strengthens trade relations but also fosters global partnerships in agricultural science, ultimately benefiting U.S. prosperity through expanded markets and innovative research solutions.

The Regional Conservation Partnership Program (RCPP) Alternative Funding Arrangements for FY 2026 aims to enhance NRCS conservation efforts through strategic partnerships. This initiative encourages collaboration among stakeholders to address critical natural resource issues across farms and watersheds. By co-investing in impactful projects, NRCS strives to improve resource management in designated Critical Conservation Areas, supporting both partners and producers in achieving sustainable outcomes.

Iowa Economic Development Authority

Mission

Strengthen economic and community vitality by building partnerships and leveraging resources to make Iowa the choice for people and business. Through two main divisions – business development and community development – IEDA administers several state and federal programs to meet its goals of assisting individuals, communities and businesses. IEDA works to achieve its mission and goals to benefit Iowans while maintaining a high level of transparency. 

CDBG Planning Grants

Approximately $60,522 in federal Community Development Block Grant (CDBG) funds are available to cities and counties through the state of Iowa’s Planning Grants Program. All incorporated cities and all counties in the State, except those designated as HUD entitlement areas, are eligible to apply for and receive funds under this program.

The Planning Grants Program allows communities to seek funding for three types of planning tools: Capital Improvement Plans, Asset Management Plans, and Historic District Surveys. Each plan can help communities understand their needs and create long-term strategies for protecting public health, strengthening economies, and sustaining critical infrastructure. These plans allow communities to best steward public, cultural, and historical resources and become more resilient and fiscally stable for generations to come.

Applicants must demonstrate at the time of application that they have, at minimum, a dollar-for-dollar match to the requested award amount.

The Planning Grant Program will not have a HUD National Objective; however, plans developed with CDBG funds must state how they will develop future CDBG projects.  

CFR 200 Audit Requirements

CDBG contracts may be subject to audit. Federal Code (2 CFR 200) requires that recipients that expend $750,000 or more in federal funds within a fiscal year must have a single or program specific audit. When budgeting for CDBG funds, applicants should be aware of these audit requirements:

• For recipients of $750,000 or more in federal funds received from more than one source of federal funding, an organization-wide audit must be conducted in accordance with federal requirements outlined in 2 CFR 200.514
• For recipients of $750,000 or more in federal funds received from a single source, a project audit, targeting only transactions dealing specifically with the project, may be performed in lieu of an organization-wide audit.

Communities should consult with their accountants regarding the applicability of an audit and audit requirements.

Audit costs are a CDBG-eligible expense. Organization-wide audits can be paid with CDBG funds proportional to the amount of all other funds included in the audit. The total cost of a project audit can be paid with CDBG funds.

The Impact100 Global Veterans Awards empower women to make a significant difference by awarding grants up to $100,000 to nonprofits that serve veterans. Focus areas include art and culture, education, health and wellness, environment, and family initiatives, promoting the well-being and support of veterans across the United States. Eligible organizations must meet specific criteria, including tax-exempt status, and are encouraged to submit proposals that utilize funds effectively within two years.

The L.B. Research and Education Foundation Grant Program supports U.S.-based nonprofits focusing on innovative education and health solutions for underserved populations. Eligible organizations can apply by submitting a 400-word concept paper, and selected applicants may receive funding ranging from $10,000 to $75,000. The Foundation prioritizes projects that foster critical thinking and creativity, address health disparities, and encourage collaboration. There are no application deadlines, promoting year-round engagement.

The IA AmeriCorps Formula Grant, offered by Volunteer Iowa, aims to enhance community service and volunteering in underserved areas. This grant prioritizes projects that serve communities facing poverty, improve youth mental health access, support veterans, and promote environmental stewardship. Organizations that engage AmeriCorps members in these critical areas can receive funding to foster civic engagement and build resilient communities, ultimately contributing to national service efforts across the state.

The CFGDM Leadership Grants aim to enhance quality of life in Greater Des Moines by supporting projects that align with community needs and promote equity. These grants focus on critical areas such as housing, health, economic development, and community engagement. By fostering collaborative efforts and addressing systemic barriers, the program seeks to create lasting positive change and empower local organizations to make a significant impact on community issues.

The AWG Geoscience Idea Scholarship supports women from under-served communities to pursue careers in Earth Sciences, a field known for its lack of diversity. It offers $2,500 to three upper-division and $500 to one lower-division undergraduate student, along with a one-year AWG membership. Recipients can also be matched with mentors, enhancing their educational journey and career prospects in geoscience disciplines. This initiative aims to promote inclusion and diversity in the geoscience workforce.

Marathon Petroleum Corporation's Community Investment Grants aim to enhance community welfare through strategic partnerships with 501(c)(3) non-profits and government entities. The focus areas include workforce development, sustainability, and thriving communities, reflecting the company's commitment to making a measurable impact in regions where they operate. Eligible organizations must be U.S.-based and recognized as non-profits. The foundation prioritizes initiatives that align with its values and community needs, ensuring support for impactful projects.

The Anonymous Was A Woman Environmental Art Grants offer up to $20,000 for environmental art projects led by women-identifying artists in the U.S. and territories. Focused on themes like regeneration and eco-social engagement, the grants encourage projects that address ecological issues through ethical engagement. For the 2025 cycle, over $520,000 will be distributed, doubling previous funding. Eligible applicants must be 18+, lead artists, and not enrolled in degree programs during the grant term.

Cell Signaling Technology’s Environmental Grants support initiatives aimed at ecosystem protection, wildlife research, and environmental education. Priority is given to action-oriented projects with at least 70% of funding allocated to those directly impacting the environment. Applications are accepted annually until May 1st, with a focus on organizations in Massachusetts, particularly the North Shore of Boston. Non-profit status is required, and discriminatory projects will not be funded.

The Iowa Agricultural Conservation Easement Program (ACEP) supports landowners in protecting and enhancing working agricultural lands through conservation easements. It offers financial assistance and technical support for maintaining agricultural practices while preserving wetlands and grasslands. Enrollment is open to eligible partners, including tribes and local governments, while prioritizing applications that maximize agricultural land protection. ACEP contributes up to 75% of the easement's market value for lands of special environmental significance.

The Iowa Agricultural Conservation Easement Program (WRE) offers financial and technical assistance to restore and protect wetlands. It aims to enhance ecosystems while allowing landowners to retain ownership. Eligible participants include private landowners and Indian tribes, who can enroll in permanent or 30-year easements. This program prioritizes projects that benefit wildlife, particularly migratory birds. Applications are accepted continuously, with funding contingent upon available resources.

The Biophilia Foundation Grants support biodiversity conservation on private lands, focusing on systemic change through community engagement. The foundation encourages organizations to submit letters of inquiry detailing their mission, tax status, funding requests, and intended outcomes. They prioritize private land conservation, ecosystem restoration, and innovative policy initiatives, especially in the arid Southwest and Chesapeake Bay regions. Grants typically range from $5,000 to $25,000, with larger amounts available for established partnerships.

Iowa Department of Health and Human Services

Iowa HHS provides high quality programs and services that protect and improve the health and resiliency of individuals, families, and communities.

Mobile Integrated Health

The Iowa Department of Health and Human Services (the Agency) is providing this notice of intent to release a request for proposal (RFP) on or around July 2026 for approximately seven Mobile Integrated Health (MIH) projects that will expand EMS‑led community care by delivering preventive, chronic disease, prenatal/postpartum, and acute care services directly to Iowans in their homes and communities. These projects will equip EMS agencies with the training, telehealth connectivity, and clinical tools needed to provide coordinated, in‑home care that reduces avoidable emergency department utilization and strengthens local access. A key objective of this initiative is to develop consistent and dependable care‑delivery patterns across rural regions, ensuring patients receive timely follow‑up, navigation support, and integrated care regardless of location. Please visit Healthy Hometowns - Iowa's Rural Health Transformation Plan | Health & Human Services for more information.

The Best and Brightest Rural Healthcare Workforce Recruitment Grant aims to enhance healthcare access in rural Iowa by recruiting qualified healthcare providers. This initiative, aligned with Iowa's Healthy Hometowns program, seeks to address workforce shortages and improve health outcomes through competitive incentives for providers. By fostering partnerships and investing in technology, the program focuses on creating sustainable care models that ensure quality healthcare delivery in underserved communities, ultimately aiming to elevate the standard of care in rural areas.

Ameriprise Community Grants focus on supporting nonprofits that enhance community vitality and meet basic needs. With over 120 years of commitment to philanthropy, Ameriprise Financial engages employees in volunteerism and grantmaking. Key giving areas include hunger relief, housing stability, and community development. Priority is given to organizations with active volunteer engagement from Ameriprise advisors and employees, creating a meaningful impact on financial independence and community resilience.

The Laird Norton Family Foundation, based in Seattle, prioritizes grants that reflect family values in arts education, climate change, human services, and watershed stewardship. Their approach emphasizes equitable educational opportunities, carbon sequestration, support for youth at risk of homelessness, and long-term ecological health. They focus on organizations that address social justice and community needs, particularly in King County, WA, and the West Coast. Note: No unsolicited applications are accepted.

The GSA Graduate Student Research Grants provide essential funding for master's and doctoral research in geological sciences for students in North America and Central America. In 2024, approximately $800,000 was awarded to 316 students, averaging around $2,500 each. The program aims to enhance the geoscience workforce, promote career development, and support diversity within the field. Applications require an appraisal from a primary advisor, and participation from underrepresented communities is encouraged.

The Doula Technical Assistance Grant aims to support and empower doulas serving pregnant and postpartum women in Iowa. This initiative, led by the Iowa Department of Health and Human Services, seeks applications from qualified applicants who can provide essential support and technical assistance to enhance the quality of care for mothers and their families. The grant is a vital resource to strengthen the doula profession and improve maternal health outcomes.

The Fund For Siouxland Grant, managed by the Siouxland Community Foundation, supports charitable initiatives in the Siouxland area. With a focus on arts, civic affairs, education, health, and human services, the fund aims to enhance community quality of life. Grants typically do not exceed $5,000, prioritizing projects that demonstrate collaboration, innovation, and broad community impact. The foundation is committed to serving diverse populations and addressing emerging needs without duplicating existing services.

The Iowa Women's Foundation Core Grants aim to support organizations that address barriers to women's economic self-sufficiency in Iowa. Since 1997, over $2 million has been awarded to initiatives that offer housing, transportation, education, employment, childcare, and mentorship. Eligible applicants include 501(c)(3) organizations and licensed childcare centers. The foundation encourages innovative solutions that empower women and girls, fostering their independence and leadership within the community.

The PMRTC Community Betterment Grant Program by Prairie Meadows supports small to medium projects aimed at enhancing community well-being. Grants range from $100 to $99,999 and target various sectors including arts, education, health, and economic development. This initiative aims to uplift Iowans by funding essential services, creating educational opportunities, and improving access to arts for underserved populations. The program reflects Prairie Meadows' commitment to fostering positive change in Central Iowa communities.

The Hope Funds for Cancer Research offers a three-year Postdoctoral Fellowship for innovative research in understanding difficult-to-treat cancers. Candidates with MD, PhD, or equivalent degrees can apply, focusing on novel approaches to cancer mechanisms and treatments. The fellowship provides a stipend starting at $56,000, with annual increases, and a travel grant of $1,500 for conferences. This initiative aims to enhance life expectancy through groundbreaking research in cancer treatment and prevention.

The Water and Environment Grant Program by the American Water Charitable Foundation supports innovative community projects aimed at improving watersheds, conserving water, and enhancing access to recreation in underserved areas. Eligible applicants include 501(c)(3) organizations and educational institutions located within American Water's service areas. Projects must be completed within 12 months, and applicants should consider budget feasibility when requesting funds. Certain organizations and projects, such as those not classified as 501(c)(3), are ineligible.