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Best Jefferson County Grants for Nonprofits in Wisconsin

Looking for grants for 501(c)(3) nonprofit organizations working in Jefferson County, Wisconsin? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$3.12B

Total funding

$5K

Median grant

9,000+ grants
$3.12B total
$5K median

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9,395 Results based on applied filters

Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCR is inviting applications for the continuation or revision of ongoing clinical trials through the UH3 Clinical Trial Required grant. This opportunity supports extensions for completing trials or longer follow-up periods, as well as revisions that are well justified. Key deadlines for submissions are set from March 2025 to January 2028, with optional Letters of Intent encouraged thirty days prior to application due dates. Ensure compliance with the outlined requirements to enhance your chances of funding.
Dental Health

Wildlife Annual Grants - Established Investigator ( Avian/Fish/Invertebrates)

Morris Animal Foundation
Private
Afghanistan, Algeria +166 more
Approximately US $100,000
Morris Animal Foundation invites Established Investigators to submit pre-proposals for research focused on reptile and amphibian health. This initiative emphasizes the importance of animal health and welfare while facilitating impactful conservation efforts. Proposals must demonstrate clear animal health needs, collaborative strategies, and potential benefits to wildlife populations. Funding for these projects is anticipated to average around $100,000 over a maximum duration of 36 months, fostering innovative solutions for pressing health challenges in these species.
Herpetology Wildlife Health

Brownfields Grant Program (WI)

Wisconsin Economic Development Corporation (WEDC)
State/Local Government
Wisconsin
Up to US $250,000
The Brownfields Grant Program in Wisconsin aims to revitalize contaminated industrial or commercial sites, promoting economic growth and community development. This initiative supports applicants with funds for environmental assessments and remediation efforts, turning neglected properties into viable spaces for redevelopment. Eligible candidates must provide recent environmental reports and demonstrate the inability of the responsible party to pay for cleanup. By facilitating the transformation of these brownfields, the program enhances local economies and community welfare.
Environmental Contamination & Pollution

Wisonsin Opportunity Attraction Fund (WI)

Wisconsin Economic Development Corporation (WEDC)
State/Local Government
Wisconsin
US $100,000 - US $5,000,000
The Wisconsin Opportunity Attraction Fund aims to strategically invest in the state's economy by attracting major events and programs. Managed by the Wisconsin Economic Development Corporation, this fund enhances Wisconsin's visibility as a prime destination for travel and business. The program supports eligible entities in securing opportunities through competitive bidding, ultimately driving economic impact and boosting tourism and out-of-state talent attraction. This initiative reflects Wisconsin's commitment to fostering economic growth and community well-being.
Tourism Economic Services & Development

Wildlife Health (Reptile and Amphibian) - First Award

Morris Animal Foundation
Private
Afghanistan, Algeria +166 more
Up to US $120,000
The Morris Animal Foundation invites research pre-proposals for the Wildlife Health (Reptile and Amphibian) - First Award, aimed at enhancing the health and welfare of amphibians and reptiles. This initiative focuses on impactful research, particularly in chytrid disease. Eligible applicants include early career researchers with appropriate qualifications and a clear understanding of animal health challenges. Projects should demonstrate collaboration with relevant stakeholders and provide direct benefits to wildlife populations, emphasizing conservation through an animal health perspective.
Herpetology Wildlife Health

Wildlife Health (Reptile and Amphibian) - Pilot Study Awards

Morris Animal Foundation
Private
Afghanistan, Algeria +166 more
Up to US $20,000
The Morris Animal Foundation is offering Pilot Study Awards focused on reptile and amphibian health and welfare, particularly for chytrid research. These awards aim to fund innovative, proof-of-concept studies that demonstrate a clear understanding of animal health issues and collaboration with stakeholders. Proposals must have a direct impact on wildlife populations and adhere to strict health study policies. The maximum funding is $20,000 for a duration of 12 months, ensuring significant contributions to wildlife health advancements.
Herpetology Wildlife Health

Vibrant Spaces Grant (WI)

Wisconsin Economic Development Corporation (WEDC)
State/Local Government
Wisconsin
US $25,000 - US $50,000
The Vibrant Spaces Grant in Wisconsin aims to enhance community well-being by funding public space improvements. Local governments can apply for grants ranging from $25,000 to $50,000. Key eligibility criteria include a 1:1 match requirement and community engagement. Projects should create vibrant gathering spaces, increase foot traffic, and support local businesses. The initiative fosters connections and encourages diverse activities, making it a vital resource for revitalizing underutilized areas and promoting economic growth.
Community Development & Revitalization Parks & Public Spaces Public Infrastructure

Apple Crop Protection Request for Proposals

Washington Tree Fruit Research Commission
State/Local Government
United States
Unspecified amount
The Washington Tree Fruit Research Commission is inviting research proposals aimed at apple crop protection, emphasizing organic practices and pollinator protection. Key areas of focus include the management of pests like Codling Moth and Fire Blight, testing new crop protection products, enhancing soil health, and developing efficient monitoring techniques. Collaboration among institutions is encouraged, and projects should aim for practical industry applications to ensure sustainable and profitable tree fruit production.
Agricultural Crops Agricultural Pest Management Pollinator Conservation

Small Business Development Grant (WI)

Wisconsin Economic Development Corporation (WEDC)
State/Local Government
Wisconsin
US $50,000 - US $250,000
The Small Business Development Grant (SBDG) in Wisconsin aims to enhance local economies by providing financial support to small business development organizations. With awards ranging from $50,000 to $250,000, the program targets local and regional Economic Development Organizations, municipalities, tribal governments, and counties to foster innovative support for small businesses. This initiative addresses the ongoing challenge of accessing capital, encouraging diverse and rural business growth while ensuring community involvement in program development.
Business Development

Idle Sites Redevelopment Program (WI)

Wisconsin Economic Development Corporation (WEDC)
State/Local Government
Wisconsin
Up to US $250,000
The Idle Sites Redevelopment Program by the Wisconsin Economic Development Corporation (WEDC) aims to rejuvenate abandoned or underused sites in Wisconsin. This program offers grants to local governments for redevelopment efforts, enhancing local economies and community quality of life. Eligible projects can utilize funds for demolition, environmental remediation, and infrastructure improvements, with a focus on transforming blighted properties into valuable community assets. Preference is given to projects in high-density urban areas.
Environmental Contamination & Pollution Community Development & Revitalization

Community Development Investment Grant (WI)

Wisconsin Economic Development Corporation (WEDC)
State/Local Government
Wisconsin
Up to US $250,000
The Community Development Investment Grant in Wisconsin aims to enhance economic well-being through strategic investments in urban, small city, and rural redevelopment projects. This program supports initiatives that are shovel-ready and focus on revitalizing commercial corridors. Eligible applicants include municipalities and designated private developers, with funds available for activities like building renovation, historic preservation, and infrastructure improvements, fostering job creation and increased property values.
Community Development & Revitalization Historic Preservation Public Infrastructure +2 more

Intoxicated Driver Program Supplemental Funding (WI)

Wisconsin Department of Health Services
State/Local Government
Wisconsin
Unspecified amount
The Intoxicated Driver Program Supplemental/Emergency Funding in Wisconsin aims to support Tribal nation treatment agencies and counties facing funding shortfalls for services provided to impaired drivers. Eligible applicants must demonstrate financial need, efforts to collect fees, and accurate reporting of expenditures. This funding is critical for ensuring that treatment services can continue effectively amidst growing demands and challenges, ultimately leading to improved outcomes for clients.
Addiction & Substance Use Disorders Health Facilities & Clinics Automotive Safety

Room and Board Residential Substance Use Disorder Opioid Settlement Funds

Wisconsin Department of Health Services
State/Local Government
Wisconsin
Unspecified amount
The Wisconsin Department of Health Services is offering funding to cover room and board costs for Medicaid members with an opioid use disorder or at risk for an overdose in residential treatment programs. This initiative aims to enhance access to essential services for individuals facing barriers due to non-reimbursable room and board expenses. With $2.75 million allocated from the National Prescription Opiate Litigation settlement, eligible Tribal nations and counties can apply to support affected individuals in their recovery journey.
Addiction & Substance Use Disorders Drug Use Disorder

Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH is inviting applications for interventions aimed at enhancing cancer screening and preventive services in underserved populations. This initiative focuses on addressing barriers to healthcare access and promoting timely follow-up on abnormal findings. Collaborations with community partners are encouraged to foster effective outreach. The program particularly seeks to engage patients, clinicians, and healthcare settings in improving health equity and outcomes in cancer prevention.
Health Disparities & Social Determinants of Health Cancer / Oncology Preventative Healthcare

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed) (356717)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The National Cancer Institute (NCI) seeks to enhance the validation of biomarkers and assays for cancer detection and treatment through its UH3 funding mechanism. This initiative supports multi-disciplinary collaborations to validate existing assays over three years using clinical trial specimens. Emphasis is placed on harmonizing laboratory tests and validating pharmacodynamic markers. Projects should not focus on early-stage technology development but aim for integration into clinical studies as investigational assays.
Cancer / Oncology Biomedical Imaging

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed) (356718)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
The National Cancer Institute (NCI) invites applications for the validation of molecular, cellular, and imaging markers for cancer detection and treatment. This funding opportunity supports both analytical and clinical validation phases, emphasizing multi-disciplinary collaboration. The UH2 phase focuses on analytical validation, while the UH3 phase extends to clinical validation using well-annotated biospecimens. Proposals should justify the relevance of assays for clinical use and may include harmonization efforts across laboratories.
Cancer / Oncology Biomedical Imaging

Mechanism for Time-Sensitive Substance Use Research (R21 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
The Mechanism for Time-Sensitive Substance Use Research (R21 Clinical Trial Optional) invites applications that address urgent research needs in substance use epidemiology and health services. This funding opportunity encourages pilot studies focusing on emerging drug issues, unexpected prescription drug abuse trends, and timely medical system challenges. Letters of Intent are recommended 30 days before the proposal deadline, emphasizing the necessity for rapid review and funding to address pressing scientific questions.
Addiction & Substance Use Disorders Drug Use Disorder

C Spire Wireless Foundation Grant

C Spire Wireless Foundation
Private
United States
Unspecified amount
The C Spire Wireless Foundation Grant supports STEM education initiatives in Mississippi, Tennessee, and Alabama. Aimed at 501(c)(3) organizations, it focuses on projects that enhance digital literacy, technology skills, and workforce development. With a commitment to community transformation, the foundation prioritizes local projects that improve tech education and broadband access, creating a stronger future for the region. Applications must be submitted 150 days before the event, with a review period of up to four weeks.
STEM / STEAM Education Workforce Preparation & Job Readiness Technology Access & Digital Literacy

C Spire Wireless Foundation Sponsorship

C Spire Wireless Foundation
Private
United States
Unspecified amount
The C Spire Wireless Foundation provides sponsorships primarily focused on STEM education, aiming to enhance digital literacy and workforce development in underserved communities. Organizations eligible for support must be 501(c)(3) tax-exempt entities dedicated to these educational initiatives. Preference is given to projects based in the foundation's service region. Proposals should be submitted at least 90 days prior to events for consideration, with a review process taking two to three weeks.
STEM / STEAM Education Workforce Preparation & Job Readiness Technology Access & Digital Literacy

Ernest F. Hollings Undergraduate Scholarship

National Oceanic and Atmospheric Administration (NOAA)
Federal Government
American Samoa, Guam +4 more
Up to US $40,000
The Ernest F. Hollings Undergraduate Scholarship offers up to $9,500 annually for two years, alongside a paid summer internship at NOAA. This program enhances students' training in oceanic and atmospheric sciences, aiming to increase public understanding and support for environmental stewardship. Eligible students must be U.S. citizens, enrolled full-time in relevant disciplines, and maintain a minimum GPA of 3.0. The experience fosters valuable skills and networks, with 100% of alumni recommending the scholarship.
Humanities & Social Science STEM / STEAM Education Engineering +12 more

NICHD Resource Program Grants in Bioinformatics (P41 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $8,750,000
The NICHD Resource Program Grants in Bioinformatics aim to support the operation and enhancement of vital bioinformatics databases for research on animal models of embryonic development. These grants promote user training, data curation, and interoperability with NIH resources, ensuring wide dissemination of critical tools and resources to the research community. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged 30 days prior to the proposal deadline.
Biomedical informatics Developmental Biology / Embryology

AI for Economic Opportunity Fund

Gitlab Foundation
Private
United States
Up to US $250,000
The AI for Economic Opportunity Fund, established by the GitLab Foundation, aims to catalyze transformative economic opportunities using advanced AI technologies. This funding round invites bold proposals that leverage AI to enhance economic mobility, improve service delivery, and create new educational pathways. Grantees will receive $250,000 in funding, technical support, and access to a network of practitioners. The fund seeks projects that demonstrate ethical awareness and promote fairness in AI deployment.
Economic Rights, Justice, & Mobility Artificial Intelligence (AI) Economic Services & Development

BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BRAIN Initiative's funding opportunity aims to support the establishment of facilities at minority-serving and IDeA-eligible institutions for the production and distribution of brain cell type-specific reagents. These reagents will enhance neuroscience research by enabling precise manipulation and access to brain cell types, facilitating advancements in understanding circuit functions in various species. The initiative encourages collaboration among awardees to optimize the use of these essential resources across the neuroscience community.
Neuroscience

Wallerstein Foundation Grant

Wallerstein Foundation for Geriatric Life Improvement Inc.
Private
United States
Unspecified amount
The Wallerstein Foundation for Geriatric Life Improvement is dedicated to enhancing the lives of elderly individuals through targeted support for non-profit organizations. Grants focus on critical areas such as dementia care, wellness programs, and community engagement initiatives. The foundation prioritizes projects that meet the unique needs of seniors, promoting health and active lifestyles. By funding specific projects rather than general support, the foundation aims to make a meaningful impact on the quality of life for senior citizens.
Senior Services Aging / Gerontology Dementia & Alzheimer’s Disease +3 more

Ruby Bridges Walk to School Day Mini-Grant

Safe Routes to School National Parternship
Private
United States
US $500 - US $1,000
The Ruby Bridges Walk to School Day Mini-Grant supports events that honor civil rights activist Ruby Bridges by encouraging students to walk to school and engage in discussions about activism, anti-racism, and anti-bullying. Grants of $500 or $1000 are available based on the number of students reached. This initiative aims to inspire positive changes within communities and promote meaningful dialogue among young people about social justice issues.
Youth Services Civic Engagement & Education Racial / Ethnic Justice & Rights +2 more

Gilead Medical Education Grants - Independent Medical Education Funding

Gilead Sciences Foundation
Private
American Samoa, Guam +4 more
Unspecified amount
Gilead Medical Education Grants fund innovative, data-driven programs that enhance healthcare infrastructure and support vulnerable communities globally. Focused on core therapeutic areas like HIV, liver diseases, and oncology, these grants aim to deliver impactful continuing medical education for healthcare providers. Eligible applicants include for-profit medical education companies and nonprofit organizations. Gilead prioritizes programs that demonstrate a strong capacity to achieve specific educational outcomes, ensuring that support reaches those who need it most.
Medical Education & Professional Training

Sheldon Danziger Pipeline Grants

Russell Sage Foundation
Private
United States
Up to US $65,000
The Pipeline Grants Competition by the Russell Sage Foundation aims to bolster early-career scholars and enhance diversity in the social sciences. It supports innovative research focusing on economic mobility and systemic inequalities in the U.S. Eligible applicants can receive up to $35,000 individually or $50,000 in teams. The foundation emphasizes methodological diversity and interdisciplinary collaboration, encouraging novel data usage. Projects should align with RSF's mission to improve social conditions, prioritizing underrepresented scholars from under-resourced institutions.
Climate Change Resilience & Equity Economic Rights, Justice, & Mobility Social Justice / Human Rights +8 more

Jefferson County Grants for Nonprofits Highlights

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Read more about each grant below or start your 14-day free trial to see all Jefferson County grants recommended for your specific programs in Wisconsin.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in Wisconsin

Average Grant Size

What's the typical amount funded for Wisconsin?

Grants are most commonly $92,581.

$92,581

Total Number of Grants

What's the total number of grants in Jefferson County Grants for Nonprofits year over year?

In 2024, funders in Wisconsin awarded a total of 49,160 grants.

2022 45,256

2023 45,044

2024 49,160

Top Grant Focus Areas

Among all the Jefferson County Grants for Nonprofits given out in Wisconsin, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Jefferson County Grants for Nonprofits changing over time?

Funding has increased by 8.86%.

2022 $3,758,149,480

2023 $4,172,752,976
11.03%

2024 $4,542,464,251
8.86%

Wisconsin Counties That Receive the Most Funding

How does grant funding vary by county?

Milwaukee County, Dane County, and La Crosse County receive the most funding.

County Total Grant Funding in 2024
Milwaukee County $1,633,180,004
Dane County $1,188,297,084
La Crosse County $284,177,520
Waukesha County $242,610,917
Brown County $192,021,811