Best Large Grants for Nonprofit Organizations in Kentucky

The L&L Nippert Charitable Foundation Grant supports organizations that enhance the lives of residents in the Tri-State Area through cultural arts, education, environment, or health initiatives. Established in 1981, the foundation is committed to continuing the philanthropic legacy of Louis and Louise Nippert. Eligible organizations must be 501(c)(3) public charities and demonstrate a clear benefit to the community. This grant aims to foster opportunities that align with the foundation's mission.

The ISF Policy Scholarship Program offers financial assistance ranging from $3,000 to $5,000 for scholars dedicated to improving Muslim representation in media and government. Since 2009, ISF has awarded 747 scholarships to students in fields that influence public policy and opinion, such as political science and international relations. With a commitment to mentorship and real-world experience, ISF aims to foster positive narratives about American Muslims and encourage their involvement in the policymaking process.

The Foist Family Perseverance Scholarship Fund, established by the Berkshire Taconic Community Foundation, aims to support adult learners and graduating high school seniors from Berkshire County pursuing careers in healthcare and sciences. With a focus on clinical and research fields such as nursing and occupational therapy, this fund seeks to empower individuals in their educational and professional journeys, promoting economic mobility and high quality of life in the community.

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

June M. and John C. Vandervelde Scholarship

This scholarship has been made possible by the generosity of June M. and John C. Vandervelde, who established the June M. and John C. Vandervelde Scholarship of the Community Foundation for Muskegon County. The Vandervelde's are both long-time Muskegon residents. Many Muskegonites will recognize the name "Vandervelde Furniture" which was located on Broadway in Muskegon Heights for many years. Generations of people bought their furniture from Vandervelde's. June is a long active volunteer for many community organizations, and both have a strong belief in and recognize the importance of a college education. This scholarship fund will assist Muskegon County students as they pursue that education.

The In These Mountains: Infrastructure Grants, offered by South Arts, aim to preserve and promote the folk arts and traditional culture of Central Appalachia. This initiative supports non-profit organizations in Kentucky, North Carolina, and Tennessee, focusing on enhancing the resources necessary for sustaining and advancing traditional arts. Grants of up to $30,000 are available to address non-programming expenses, ensuring the continuity of cultural practices while prioritizing inclusivity and accessibility.

The Michigan Health Endowment Fund offers Scholarships for Conferences and Professional Development to support health-related events. These scholarships, up to $2,500 per person and $5,000 per organization, are available for current or past grantees and partners. Applications are accepted on a rolling basis, with a requirement to submit at least four weeks before the event. Priority is given to organizations that haven't received funding in the previous year, ensuring equitable access to professional development opportunities.

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Ken and Clara Kolberg Family Scholarship

This scholarship has been made possible by the generosity of Ken Kolberg and family, who established the Ken and Clara Kolberg Family Scholarship of the Community Foundation for Muskegon County. Teaching is the family business of the Kolberg Family. Ken started teaching in Muskegon Public Schools after WWII and did so for thirty-seven years. Ken and Clara raised five children, of whom four became teachers - two working in Muskegon. Through the establishment of this Fund, the family is assured of having an impact on students far into the future. This Fund will support Muskegon students pursuing careers in education, especially minority students so greatly needed as teachers in our school systems.

The ISF Narrative Film Grant, established by the Islamic Scholarship Fund, supports emerging Muslim filmmakers by providing funding for narrative films in production or post-production stages. With a focus on compelling storytelling and positive portrayals of the Muslim community, the grant offers mentorship and networking opportunities to enhance the filmmakers' projects. Since its inception in 2014, it has awarded $625,000 to over 111 filmmakers, promoting diverse narratives that resonate with audiences.

The Ford Philanthropy Scholarship, offered by the LULAC National Educational Service Centers (LNESC), supports students pursuing STEM careers in the automotive and mobility sectors. It covers tuition, fees, and essential resources, enabling students to thrive academically. Applicants must major in relevant fields such as Computer Science or Engineering and maintain a GPA of 3.5 or higher. This initiative enhances educational access and fosters leadership, preparing students for future success.

The Domtar Community Investment Grant supports nonprofits and charities in areas where the company operates, focusing on education, environmental sustainability, and community humanitarian needs. Eligible organizations include charitable groups, while ineligible entities encompass individuals, discriminatory organizations, and political causes. Applications are accepted online from January 1 to November 30, with reviews conducted bi-monthly. This initiative aims to create meaningful connections between charitable efforts and the social benefits derived from Domtar's business operations.

The ARL Distinguished Postdoctoral Fellowships offer early career researchers a chance to engage in independent research aligned with the Army Research Laboratory's mission. Candidates should demonstrate exceptional scientific abilities and a potential for leadership, having addressed significant scientific or engineering challenges during their doctoral studies. Fellowships provide a stipend of $115,000 per year, along with health insurance and other benefits. Applicants must have completed their Ph.D. by October 1, 2025, and are required to undergo a Department of Defense clearance.

The Rev. Robert L. Browning Memorial Scholarship, managed by the Decatur County Community Foundation, supports students from Decatur County pursuing careers in ministry or social services, as well as those planning to attend Anderson University. This scholarship is renewable for up to three years and is aimed at graduating high school seniors residing in Decatur County, IN. Preference is given to applicants who attend the Church of God.

The Small Business Transition Grant for New Entrepreneurs, funded by the NIH, supports new investigators in entrepreneurship. This grant aims to enhance the entrepreneurial skills of researchers while facilitating their research and development efforts in small businesses. It encourages the employment of Program Directors/Principal Investigators (PDs/PIs) who possess strong scientific expertise but limited entrepreneurial experience, fostering innovation aligned with NIH's mission to improve health and save lives.

Deb & John Quirk Memorial Scholarship

The Hastings Community Foundation is excited to announce the creation of the Deb and John Quirk Memorial Scholarship. The scholarship will provide a $10,000 annual scholarship and is renewable for a total award of up to $40,000. One scholarship will be awarded each year. This scholarship is only available to graduating seniors from Hastings High, Adams Central, or Hastings Catholic Schools. Applicants must be focused on impacting social justice through their education and future employment, as illustrated through an essay submitted to the scholarship committee.

The Japanese American Community Foundation Grants support programs for the Japanese American and broader Asian American communities. Funding ranges from $2,500 to $50,000 for projects focusing on senior health, history, arts, culture, and youth. Eligible applicants must be registered 501c3 public benefit nonprofit organizations. Note that organizations with open grants cannot apply until their current grant is closed. Submit a Letter of Inquiry (LOI) before the full proposal.

The JAMS Foundation / NAFCM Mini-Grant Program offers funding to support innovative community mediation programs that foster sustainability and growth. This initiative emphasizes conflict resolution training for local leaders, enabling them to effectively address community issues. Through structured peer interactions, grantees share best practices and insights. Resources generated by the program are freely accessible to enhance the wider community mediation field, ensuring shared knowledge and enhanced practices across the nation.

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Grants & Fellowships

Early Career Mini-Grant

The Mensa Foundation empowers emerging researchers through its Early Career Mini-Grant program.

Designed to support post-doctoral researchers and early career faculty, this grant funds innovative studies that advance our understanding of intelligence, creativity, gifted education, and related fields.

Details

The Early Career Mini-Grant provides $2,500 to support post-doctoral researchers and faculty within five years of completing their doctoral degree. This grant is intended to promote groundbreaking studies that advance our understanding of intelligence and its applications in education and beyond.

Grant Components

The Blueprint MedTech Translator program aims to support the advancement of therapeutic and diagnostic devices for nervous and neuromuscular disorders. This initiative encourages clinical feasibility studies and the implementation of clinical prototype devices, along with safety and efficacy testing. Participants will receive funding to conduct research in their own labs, collaborate with NIH consultants, and access contract research organizations for specialized testing, ensuring a comprehensive approach to device development.

About Boeing

A leading global aerospace company and top U.S. exporter, Boeing develops, manufactures and services commercial airplanes, defense products and space systems for customers in more than 150 countries. Our U.S. and global workforce and supplier base drive innovation, economic opportunity, sustainability and community impact. Boeing is committed to fostering a culture based on our core values of safety, quality and integrity.

The Employees Community Fund (ECF) of The Boeing Company

One of the largest employee-managed funds of its kind in the world, the Employees Community Fund (ECF) of The Boeing Company has empowered employees to make a greater impact by pooling their tax-deductible donations for more than 60 years. Employee-led grantmaking committees at 20 Boeing sites provide combined employee donations to nonprofits in their communities through ECF grants.

Charitable or educational organizations can apply for grants from the Employees Community Fund (ECF) of The Boeing Company.

Puget Sound Chapter

The Employees Community Fund (ECF) of Boeing Puget Sound is a pooled fund consisting of recurring payroll contributions from generous Boeing employees. It funds local nonprofits that help thousands of families and individuals in the Puget Sound region where Boeing employees live and work.

ECF focus areas

ECF makes grants to 501(c)(3) Health & Human Service nonprofits such as food banks, job-training programs, shelters, transitional housing, mental health services, and low-income medical clinics. ECF seeks the direct client benefit of each grant to ensure that our employees’ contributions directly help those in need.

ECF funding criteria

ECF has two distinct grant categories – Supporting Grants and Capital Campaign Grants.

ECF of Boeing Company: Puget Sound Chapter Supporting Grants

Consideration is given to nonprofits/agencies that are performing well and are seeking to upgrade, replace or modify elements of their infrastructure.

• Supporting grants cannot exceed $50,000. The requested amount cannot be more than 10% of an agency’s gross annual revenue.
• Supporting grants will be considered only for agencies benefiting residents in the Puget Sound Region.
• Supporting grants help agencies continue to effectively provide services through enhanced direct client benefit by aiding them in procuring and/or paying for items such as:
  • Equipment (ex. office, kitchen, industrial, furniture, etc.)
  • Vehicles used to support clients and/or transport food and/or goods (cost of vehicle and accommodations, tax, and licensing only; operating expenses, such as insurance, fuel, etc. is not allowed)
  • Phone systems
  • Cell phones for direct client use
  • Remodels and/or renovations (must hold at least a 10-year lease or own the building)
  • Purchase or construction of new buildings
  • Computers or tablets for direct client benefit and/or use
  • Software for direct client benefit and/or use (ex. Augmentative and alternative communication (AAC) device)
  • Information Technology expenses, without which procured tools would not work
  • External improvements for client safety (i.e. security system, exterior lighting, improved ADA accessibility, new or refinished pavement or concrete)
• Supporting grants which are accepted must be spent as approved within nine (9) months.

Alliance for Cancer Gene Therapy

Unlike surgery, chemotherapy and radiation, cell and gene therapies harness the power of your immune system to destroy cancer cells without harming healthy tissue. We fund the research that will make this vision a reality.

Collaborating with partners and funding research fellows, we are transforming cancer treatments today while bringing the world closer to a cure for all cancers tomorrow.

ACGT Investigator Award in Cell and Gene Therapy for SOLID TUMOR CANCERS 

Purpose

Alliance for Cancer Gene Therapy, Inc. (ACGT) funds breakthrough research that is transforming cancer treatment through cell and gene therapy. This ACGT grant award is for those conducting translational cell and gene therapy research specifically in solid tumor cancers.

Research Objectives

Cell and gene therapy for solid tumors poses major challenges driven by antigen heterogeneity, physical exclusion, immunosuppressive microenvironments, genomic instability, and safety limitations. This RFA seeks innovative, translational cell and gene therapy strategies that directly address these barriers.

Proposed approaches should demonstrate the capacity to: (1) overcome antigen escape through multi-targeted designs that broaden patient populations and account for heterogeneity and resistance due to antigen loss; (2) enhance trafficking, infiltration, and persistence within solid tumor sites; (3) resist or reprogram the immunosuppressive tumor microenvironment; and (4) incorporate built-in safety and controllability mechanisms suitable for clinical translation. Successful proposals will integrate these elements to enable durable, precise, and scalable therapeutic impact in solid tumors.

Building on the priorities outlined above, this RFP encourages proposals spanning a broad range of cell and gene therapy (CGT) platforms and rational combinations, including but not limited to:

• Engineered T Cell Approaches
• Innate and Alternative Immune Cell Platforms
• Gene Editing & Synthetic Biology Strategies
• Microenvironment-Modulating Strategies
• Combinatorial Approaches

Proposals that integrate multiple strategies to overcome trafficking, suppression, antigen escape, and safety barriers in a coordinated manner are strongly encouraged. Preference will be given to approaches with clear mechanistic rationale and a credible path toward clinical translation in solid tumors.

Mission

The Social Science Research Council (SSRC) is an independent, international, nonprofit organization founded in 1923. The Council fosters innovative research, nurtures new generations of social scientists, deepens how inquiry is practiced within and across disciplines, and mobilizes necessary knowledge on important public issues.

SSRC-JF Next Gen Japan Study Tour Grants

The SSRC-JF Next Generation Japan Studies Development Program invites faculty at US colleges and universities to apply for funding of up to $32,500 maximum for institutional study tour grants. These grants are designed to provide travel funds to bring undergraduate and master’s degree students to Japan for immersive learning experiences. This program is supported by the Japan Foundation.

Background

At the core of the Next Gen Japan programming is the idea that international experience, research engagement, and collaboration are central to effectively addressing the pressing concerns facing societies today. Japan Study Tour Grants offer students the opportunity to gain a nuanced and balanced understanding of Japan while sparking an enduring interest in the country and a broader, international perspective.

Prioritie

Priority will be given to the following applications:

• Applications from the liberal arts colleges, research universities, and community colleges located in the US South and Midwest.
• Applications with travel itineraries appropriately planned to enhance the course syllabus.
• Applications with travel itineraries highlighting close collaboration with Japanese counterparts.
• Applications that demonstrate the study tour would be open to students from a variety of disciplines ranging from the humanities and social sciences to the natural sciences.

This funding opportunity aims to advance mechanistic research for precision probiotic therapies. It invites R33 applications focused on characterizing individual differences in probiotic responses, identifying responder subgroups, and enhancing clinical outcomes. The goal is to develop strategies addressing barriers to effective probiotic use, accounting for human variability. Proposals should include innovative studies using animal models or human subjects, supported by preliminary data to test biological patterns and their effects on health outcomes.

The Mifflin Memorial Fund Grant supports nonprofit organizations in human services and education, particularly those serving low-income and minority populations. This private fund also contributes to environmental and conservation initiatives, and occasionally cultural organizations for specific projects. Eligible applicants must be tax-exempt nonprofits, ensuring that grants are directed towards impactful community services and educational opportunities.

James Graham Brown Foundation

The James Graham Brown Foundation was established in 1954 by Louisville entrepreneur and philanthropist James Graham Brown. Guided by his enduring vision for Louisville and Kentucky, the Foundation carries forward his legacy of philanthropy that strengthens communities and fosters civic pride.

Louisville Responsive Community Grants

Our Louisville-based Responsive Grantmaking is designed to support projects and initiatives that contribute to Louisville’s progress and reputation. These grants respond to opportunities identified by community organizations and are designed to strengthen the city’s quality of life and overall vitality.

Responsive grants typically focus on locally driven efforts that align with the Foundation’s mission and advance Louisville as a thriving, engaged community. Projects often reflect collaboration, creativity, and a shared commitment to making the city a better place to live, work, and visit.

Outcomes

• Improved well-being of citizens of Kentucky
• Improved perceptions of Kentucky
• Civic engagement
• Opportunities for all

Focus Areas

• Education
• Community and Economic Development
• Civic and Cultural Assets
• Health and Well-being

Additional Considerations

Organizations should demonstrate significant financial support for projects, including contributions from private donors, private and public grants, and other sustainable sources of revenue. Additionally, letters of support or endorsement are appropriate to include in the application. It is also encouraged to mention current partnerships and collaborations.

• The proportion of a project budget requested from JGBF should not typically exceed 30% of the total project budget. The amount of the grant request should be appropriate for the scope of impact.
• Proposals that demonstrate 50%–60% of the total project cost raised are more competitive.
• JGBF will rarely be the sole funder and encourages a broad base of support to reinforce projects and increase the likelihood of lasting impact.
• Requests made via LOI must be approved by the applicant's CEO prior to submission.

The Judith A. Ingram Memorial Scholarship Fund, established by The Foundation for Enhancing Communities, honors the legacy of Judy Ingram, a dedicated educator who inspired many in elementary education. This scholarship supports graduating seniors from local school districts planning to major in elementary education, emphasizing academic achievement and financial need. It aims to foster future educators who will continue Judy's commitment to nurturing young minds and enhancing educational opportunities in the community.

Stark Community Foundation

Since 1963, Stark Community Foundation has been helping individuals, families, businesses and nonprofits like you support the causes you care about.

In addition to personalized donor services, we manage a competitive grantmaking program and award grants to address local needs. Today, the Foundation stewards over 1,000 charitable funds totaling $485 million in assets and has granted more than $300 million to nonprofits in our community and beyond.

Scholarships

Stark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.

The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties.

The Ken Finney Memorial Scholarship Fund

The Ken Finney Memorial Scholarship Fund assists students seeking a bachelor’s in mechanical engineering or music who are residents of Stark, Wayne or Carroll counties (or adjacent counties).

This scholarship is renewable.

Scholarships are available to graduating high school seniors. Applications are accepted from mid-November until mid-March. Scholarship award recipients will be announced at the high school awards ceremony. 

Susquehanna Beekeepers Association College Scholarship

Established by the Susquehanna Beekeepers Association to provide college tuition assistance to students from northeastern Pennsylvania who will major in agriculture or biology.