Best Large Grants for Nonprofit Organizations in Kentucky

Mission: To continually improve the Marion Area community through philanthropy, leadership and civic engagement. Eugene & Cecilia Reszczynski ScholarshipThe Reszczynski Scholarship, created in 2002, is one of the oldest at Marion Community Foundation. It makes awards each year to students who score in the top 50th percentile of the ACT or SAT and have attended a high school in Marion County for two or more years. This scholarship honors the late Eugene and Cecilia Reszczynski and their passion for helping others. 

The Cushing Scholarship was created in 2014. According to Marsha, “We are not as interested in a student’s financial status as we are on how they look at life.”

Mission: To continually improve the Marion Area community through philanthropy, leadership and civic engagement. Rocco Nicolosi Memorial ScholarshipIndividuals selected for the Nicolosi Scholarship must have attended a high school located in Marion County throughout his or her entire high school experience and have ranked in the upper 25th percentile of his or her high school senior class.To preserve Rocco’s memory and discourage future tragedies, applicants must write an essay on the topic of “Why Young People in Marion Need to be Drug, Alcohol, and Substance Free.”

Mission: To continually improve the Marion Area community through philanthropy, leadership and civic engagement. Quintin & Alice Linn ScholarshipThe Linn Fund is a scholarship, created in 2022, to support Marion County students pursing degrees and careers in economics, finance, mathematics, and statistics.

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

Cornell Goodman Scholarship

Adam and Gina Goodman created this scholarship fund in 2011 to honor the memory of Adam’s grandfathers Maurice V. Cornell and Bertram Goodman, longtime residents of the Marion area.

Maurice (1912-2001) was a graduate of Mt. Vernon High School and The Ohio State University. He held membership in Lombda Chi Alpha fraternity, Elks Lodge #32, 32nd degree Mason, Rotary, First Presbyterian Church, the Marion Country Club, and Symposiarchs. He served in the US Navy during World War II in the South Pacific. He was vice president of Marion Power Shovel for eight years and retired as the regional manager of Bucyrus-Erie Co. after 10 years.

Bertram (1921-2003) was an orthodontist in Marion from 1946-1980. He was a US Navy veteran who served in the Korean Conflict. He was a member of the Marion Lions Club and Temple Israel.

The scholarship supports students who have attended a high school in Marion County. The fund gives special consideration to students pursuing a college degree in a business-oriented field, such as accounting, economics, finance, or marketing. Recipients must rank in the upper 25th percentile of their high school graduating class, or, if in college, maintain a GPA of 3.0 or better.

The McClure Family Foundation Grant honors the legacy of Charles and Dorothy McClure by supporting nonprofit organizations that strengthen families and communities. The foundation aims to promote the arts, historic preservation, education, faith-based initiatives, and the well-being of mankind. Eligible applicants include public charities, governmental units, and established churches. The foundation values personal connections with applicants and encourages endeavors that foster community responsibility and individual leadership.

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Acute Myeloid Leukemia (AML) Fund

Help with healthcare costs for acute myeloid leukemia

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses. 

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Chronic Lymphocytic Leukemia (CLL) Fund

Help with healthcare costs for chronic lymphocytic leukemia

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses. 

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See Approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Hemophilia Fund

Help with healthcare costs for hemophilia

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Hemophilia Health Equity Fund

Help with healthcare costs for hemophilia (health equity fund)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code. 

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Mucopolysaccharidosis Type III (MPS III) Fund

Help with healthcare costs for mucopolysaccharidosis type III

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses. 

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Mucopolysaccharidosis Type VII (MPS VII) Fund

Help with healthcare costs for mucopolysaccharidosis type VII

This TotalAssist Health Equity Fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Mucopolysaccharidosis Type VII (MPS VII) Health Equity Fund

Help with healthcare costs for mucopolysaccharidosis type VII (health equity)

This TotalAssist Health Equity Fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code.

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

The Yip Harburg Foundation Grant supports projects that promote economic and social justice through grants and scholarships. This foundation honors the legacy of E.Y. "Yip" Harburg by funding theater programs that convey socially responsible messages. Grants range from $500 to $5,000 and are available to registered 501c3 organizations. Applications are reviewed quarterly, so interested parties should ensure their projects align with the foundation's mission.

The Sociological Initiatives Foundation Grant supports research linking social action to addressing systemic inequalities in the U.S., funding projects that tackle racism, classism, and human rights violations. It prioritizes initiatives that foster partnerships between academia and community organizations, aiming to enhance advocacy and public knowledge. Grants typically range from $15 to $25,000, emphasizing research with tangible community impacts rather than mere reporting. The Foundation seeks projects that can fundamentally change societal structures and improve equity.

The Lisa and Douglas Goldman Fund, established in 1992, focuses on enhancing education and literacy in the San Francisco community. It supports organizations classified as public charities with 501(c)(3) status, prioritizing projects that strengthen public education and promote civic education for grades K-12. Grant requests are by invitation only and are considered quarterly. The fund seeks to make informed, flexible grants that align with its mission to support impactful charitable projects.

The Herb Block Foundation offers the Encouraging Citizen Involvement Grant to promote civic engagement and voter participation in a nonpartisan manner. Grants ranging from $5,000 to $25,000 are available for nonprofit organizations classified as 501(c)(3). This initiative aims to strengthen democracy by fostering responsible citizen involvement without supporting partisan activities or lobbying efforts.

The Herb Block Foundation's Defending Basic Freedoms Grant aims to uphold the essential freedoms outlined in the Bill of Rights. This initiative focuses on combating discrimination and prejudice while enhancing the lives of the underprivileged. It provides funding for charitable and educational programs that align with these values. Open to 501(c)(3) nonprofit organizations nationwide, the grant encourages accountability among government agencies and supports relevant contemporary societal issues.

The Established Clinician Investigator Award to Support Mentoring (KS1) is designed to provide established clinician investigators with dedicated time for mentoring early-career clinician research scientists. This initiative by the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to enhance the quality of mentorship, fostering the development of future leaders in clinical research. It supports a sustained commitment to training and guidance, ensuring a robust pipeline of skilled professionals.

The Mentored Career Transition Award (KT1/R00) offers a biphasic funding opportunity for up to 5 years, supporting the transition of postdoctoral researchers to independent faculty positions. The first phase provides 1-2 years of mentored career development, while the second phase grants up to 3 years of independent research support, contingent upon satisfactory progress and faculty appointment. This grant aims to enhance the capacity of early-career researchers in achieving research-intensive roles.

The Mentored Clinician Research Scientist Career Development Award (KC1) from the NIH supports clinician research scientists for up to five years, providing dedicated time for intensive research career development. This award aims to guide candidates with clinical doctoral degrees towards achieving research independence by pairing them with experienced mentors who can help navigate their career paths.

The Mentored Research Scientist Career Development Award (KR1) offers crucial support for researchers aiming for independence. Funded by the US Dept. of Health & Human Services through the NIH, this award allows candidates to engage in intensive research training under a mentor's guidance for up to five years. It is designed for those with research doctoral degrees, facilitating their transition into independent research roles and enhancing their contributions to the scientific community.

The FY 2027 State and Regional Primary Care Association (PCA) Cooperative Agreements aim to enhance the technical assistance provided to Health Center Program award recipients and look-alikes. This initiative focuses on improving access to preventive and primary health care, managing chronic diseases, and ensuring a capable health center workforce. By implementing value-based care strategies and leveraging data for operational improvements, the program seeks to support the health of vulnerable communities effectively.

The BETA Scholarship Fund, managed by the Brown County Community Foundation, provides financial support to residents of Brown County, Indiana, under the age of 25. This scholarship is designed for individuals pursuing education or certification at vocational, trade, or skills schools. Since its inception, the Foundation has focused on enhancing educational opportunities for local youth, ensuring that financial barriers do not hinder their academic aspirations.