Best Large Grants for Nonprofit Organizations in Kentucky

This grant opportunity aims to advance research on how work impacts health disparities among U.S. populations. It invites innovative proposals that explore the interplay between occupation and health outcomes, particularly in communities experiencing health and healthcare inequalities. Deadlines for applications span from February 2025 to October 2027, encouraging timely submissions for various categories including standard and AIDS-related grants.

The Collegiate Community Hub Grant, offered by the United States Tennis Association (USTA) in collaboration with the ITA, provides up to $10,000 to collegiate organizations operating a tennis facility as a new 'Collegiate Community Hub.' This initiative aims to enhance community engagement by offering accessible tennis instruction and playing opportunities for all ages. Eligible facilities must meet specific operational criteria and demonstrate their commitment to serving the local community.

The James McKeen Cattell Sabbatical Grant, provided by the James McKeen Cattell Fund, offers supplementary financial support for psychologists' sabbaticals. This grant is designed for faculty members at U.S. and Canadian institutions who meet specific eligibility criteria, including tenure status and recent leave history. The maximum award is capped at $40,000 or half the recipient's salary, ensuring that recipients can extend their research time effectively.

The NIAID aims to enhance infectious disease research by supporting human microphysiologic systems (MPS) development. These in vitro platforms mimic human tissue functions, promoting drug and biological product development while reducing animal use. This initiative aligns with NIH’s commitment to innovative research practices and regulatory acceptance. By focusing on MPS in infectious disease contexts, NIAID seeks to streamline therapeutic advancements and establish robust human tissue models, addressing critical challenges in understanding and treating infections.

Stark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.

The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties. In 2025, more than $1,000,000 was awarded to local students to help them achieve their educational dreams.

The Clark H. and Louise A. Criss Charitable Fund

The Clark H. and Louise A. Criss Charitable Fund was established to assist Stark County, OH high school graduates attending a two or four year university, college, or technical school. 

Amount:

• Varies. Minimum $500.

Renewable:

• Yes

The Elsa U. Pardee Foundation has been a pioneer in cancer research funding since 1944, providing over $110 million to more than 300 institutions across the U.S. It supports innovative approaches by both new and established researchers, ensuring diverse ideas receive necessary funding. Additionally, the Foundation addresses immediate financial needs for cancer patients, allocating about one-third of its grants to assist those in need. This dual focus on research and patient support distinguishes the Foundation in the fight against cancer.

The Filomena C. Peloro Scholarship, offered by the National Italian American Foundation (NIAF), aims to support outstanding Italian American students pursuing undergraduate or graduate studies. Applicants must maintain a GPA of 3.5 or higher and demonstrate financial need, alongside an active NIAF membership. This scholarship emphasizes cultural heritage and the contributions of Italians to American society, fostering academic excellence and community engagement among students.

This funding opportunity aims to enhance the global response to rabies through innovative, cost-effective tools. The initiative focuses on reducing human rabies cases and advancing canine rabies elimination, particularly in high-burden regions. Research areas include tracking vaccination efforts, managing rabies exposure investigations, improving laboratory systems, and assessing the economic impact of interventions. Ultimately, it seeks to develop strategies that protect public health and ensure the sustainability of rabies-free status in the U.S.

The National Glaucoma Research Program, funded by BrightFocus Foundation, aims to support groundbreaking research in glaucoma. Established in 1978, the program has awarded over $35 million to 32 projects focusing on understanding and treating this disease. The Standard Awards provide $150,000 over two years for researchers with preliminary data to further their work. Eligible institutions must be non-profit and demonstrate their tax-exempt status to receive funding, fostering innovative solutions for glaucoma treatment.

The BRAIN Initiative seeks to develop innovative tools and approaches for neuroscience research, focusing on cell-specific and circuit-specific processes within the central nervous system. This initiative encourages projects that enhance our understanding of brain architecture and function through novel technologies for characterizing neural components and advancing methods for recording and modulating neural activity. Applications are invited to address significant challenges and promote transformative breakthroughs in neuroscience.

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

GFT Infrastructure, Inc. Scholarship Fund

The GFT Infrastructure, Inc. Scholarship Fund was created at The Pittsburgh Foundation to provide scholarships to the children and grandchildren of GFT Infrastructure, Inc. employees who show exceptional leadership and character.

Award Type: Single-Year Award. Previous recipients of this scholarship may not re-apply.

The Special Excellence Annual Scholarship, offered by the CIRI Foundation, supports full-time students in 4-year undergraduate or graduate programs who demonstrate exceptional academic achievements and community service. With awards up to $20,000 for one academic year, this merit-based scholarship emphasizes the importance of maintaining a minimum GPA of 3.7 and encourages contributions to the Alaska Native community. This initiative fosters educational success and economic self-sufficiency among Alaska Natives and their descendants.

The TIP Office of the US Department of State invites applications for projects aimed at combating human trafficking, adhering to the Trafficking Victims Protection Act. This initiative prioritizes prosecuting traffickers, protecting victims, and preventing trafficking through strategies outlined in the National Security Strategy, executive orders, and the annual Trafficking in Persons Report, while aligning with America First Foreign Policy priorities.

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

The Congressman Mark Foley Scholarship for Environmental Studies Fund

Must pursue an undergraduate degree in Environmental Studies.

The Patricia L. Hartman and Lois C. Hartman Scholarship Fund, managed by the San Antonio Area Foundation, supports current high school seniors and college students pursuing Associate or Bachelor's degrees in the USA. It aims to enhance educational opportunities, with a preference for applicants from Alamo Heights ISD. This fund reflects a commitment to improving community life through education, making a lasting impact on students' futures.

Napa Valley Community Foundation

We work side-by-side with local donors and nonprofits to tackle the most important challenges our Valley faces.

Our Board and staff are completely dedicated to the people and causes of Napa Valley and represent communities from American Canyon to Calistoga. They share skills, perspectives and the collaborative spirit that define our Napa Valley diversity.

Edward W. Solomon Scholarship

The Edward W. Solomon Scholarship is offered by CalRTA Napa Valley and administered by Napa Valley Community Foundation. It is awarded in memory of Dr. Edward W. Solomon. The Solomon Scholarship is given to support current Napa County teachers/educators who are continuing their education. Previous recipients of the scholarship are eligible to reapply.

In addition, applicants must demonstrate the potential for academic success by having been accepted in an upcoming college or university upper division or graduate level education program or course. Community college courses are acceptable only for current teachers who want/need to supplement their credential authorizations, and if the community college course is acceptable to the CTC Credentialing Office.

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

Westmoreland County Housing Authority Scholarship Fund

The Westmoreland County Housing Authority Scholarship Fund was created at The Community Foundation of Westmoreland County, a component of The Pittsburgh Foundation, to encourage higher education and as a result, promote community responsibility, develop self-sufficiency and increase self-esteem. WCHA Scholarships are to benefit high school seniors and adults entering secondary education who reside in Westmoreland County Housing Authority public housing, Westmoreland Non Profit Housing Corporation housing or participate in the Section 8 Program and wish to continue their education.

Award Type: Single Year Award. 

The ARS New Investigator Research Grant aims to support innovative research in rhinology, including basic, translational, and clinical projects. The funding period is non-renewable and lasts up to 24 months. Eligible candidates include American Rhinologic Society members who have completed residency and lack significant prior funding. The number of grants awarded is contingent upon the merit of applications received, as determined by the ARS Board of Directors. This grant provides a unique opportunity for emerging researchers in the field.

The Hearst Journalism Awards Program, established in 1960, supports undergraduate journalism education with up to $700,000 in annual awards. The program includes multiple competitions in writing, photojournalism, audio, television, and multimedia categories. Each participating university can submit two student entries per competition, fostering excellence in journalism. Open to journalism majors or minors, the program encourages students to engage actively in campus media. The Hearst Foundation, founded by William Randolph Hearst, has contributed significantly to education and the arts nationwide.

About The NRA Foundation

The heart of The NRA Foundation’s mission is preserving the core of our American values and traditions in our steadfast effort to Teach Freedom.

The NRA Foundation Supports Freedom, Family, and the Future of the Shooting Sports

Established in 1990, The NRA Foundation, Inc. (“NRA Foundation”) is a 501(c)(3) tax-exempt organization that raises tax-deductible contributions in support of a wide range of firearm-related public interest activities of the National Rifle Association of America and other organizations that defend and foster the Second Amendment rights of all law-abiding Americans.

The heart of The NRA Foundation’s mission is preserving the core of our American values and traditions in our steadfast effort to Teach Freedom.

Established in 1990, The NRA Foundation, Inc. (“NRA Foundation”) is a 501(c)(3) tax-exempt organization that raises tax-deductible contributions in support of a wide range of firearm-related public interest activities of the National Rifle Association of America and other organizations that defend and foster the Second Amendment rights of all law-abiding Americans. These activities are designed to promote firearms and hunting safety, to enhance marksmanship skills of those participating in the shooting sports, and to educate the general public about firearms in their historic, technological and artistic context. Funds granted by The NRA Foundation benefit a variety of constituencies throughout the United States including children, youth, women, individuals with physical disabilities, gun collectors, law enforcement officers, hunters and competitive shooters.

Awards

The NRA is proud to recognize the contributions of those who have demonstrated dedication to the promotion of the Second Amendment, significantly impacted the preservation of the shooting sports, advanced the purposes and goals of the NRA and exemplified leadership through public service. Each year, women, youth, clubs, law enforcement officers and NRA Foundation volunteers are awarded for their efforts in pursuit of these principles.

NRA Law Enforcement Instructor Of The Year

The recipient is selected by NRA Law Enforcement Division staff and must be a currently certified NRA Law Enforcement Firearm Instructor. The winner will receive a plaque and a firearm, donated by Smith & Wesson, in recognition for this achievement.

The Kentucky Performing Arts: Spaces For All Fund aims to foster inclusivity in the arts by providing rental assistance to local artists and organizations. This initiative supports projects that reflect the diverse communities of the Greater Louisville area, ensuring that qualifying groups can access KPA venues at reduced rates. In-kind support ranging from $1,500 to $5,000 is available for venue expenses, enhancing the cultural landscape and making the arts more accessible.

The Northern California DX Foundation Grant supports amateur radio projects that promote education and international goodwill. It provides financial assistance for well-designed DXpeditions to rare locations, especially those generating global interest. Grants are typically awarded to expeditions that align with the foundation's mission, ensuring participants have a financial stake in their initiatives. The foundation emphasizes thorough review of operator qualifications, equipment appropriateness, and operational plans before granting support.

The Ernest L. Pellegri Scholarship, offered by the National Italian American Foundation, supports outstanding Italian American students pursuing undergraduate or graduate degrees in Latin or related fields. Applicants must demonstrate financial need and maintain a GPA of 3.5 or higher. This scholarship aims to encourage the preservation of Italian culture and heritage while promoting academic excellence within the community.

The Venturous Capital Grants aim to empower small and medium-sized not-for-profit theaters to produce bold and experimental new plays. Grants range from $5,000 to $35,000, covering extraordinary costs that enable productions to thrive. The program supports text-based, author-driven works that are ambitious, challenging, and innovative, while emphasizing the importance of playwright compensation and adhering to AEA standards. This initiative fosters creativity and helps overcome financial barriers in theater production.

The HEAL Initiative: Pain Research Enhancement Program (PREP) aims to support R15-eligible Principal Investigators in conducting rigorous pain research. This initiative promotes interdisciplinary partnerships and enhances the research environment for health professional trainees. Key deadlines include October 28, 2025, and October 27, 2026, for standard applications, and November 24, 2025, and November 23, 2026, for AIDS-related applications. Letters of Intent are encouraged 30 days prior to the due date.

Clinical Research Training Scholarship in Autoimmune Neurology

This award recognizes the vital importance of rigorous clinical and translational research and aims to inspire and support early-career investigators pursuing clinical studies in autoimmune neurology — specifically immune-mediated diseases of the nervous system other than multiple sclerosis.

The scope of this award encompasses research on autoimmune neurologic disorders, including neural antibody-associated diseases of the nervous system, autoimmune encephalitis, immune-mediated epilepsy, autoimmune movement disorders, inflammatory myelopathies, NMOSD, MOGAD, paraneoplastic neurological syndromes, neurological complications of cancer immunotherapies, and inborn errors of immunity/autoinflammatory syndromes affecting the nervous system.

This award will consist of a commitment of $65,000 per year for two years, plus a $10,000 per year stipend to support education and research-related costs for a total of $150,000. Supplementation of the award with other grants is permissible, but to be eligible to apply for this award, the other grant source(s) cannot exceed $75,000 annually.

The NIOSH Centers of Excellence for Total Worker Health® (U19) aims to enhance worker well-being by funding research and translation activities that address harmful exposures and improve working conditions. Priority areas include high-risk occupations, young workers, and chronic diseases. The initiative emphasizes strong project coordination, scientific rigor, and economic evaluations. Projects must utilize the NIOSH Worker Well-Being Questionnaire and share findings with the HERO Clearinghouse, fostering innovative solutions for employers and workers.