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Best Large Grants for Nonprofit Organizations in Kentucky

Find the perfect Large Grants for Nonprofit Organizations in Kentucky on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in Kentucky in the United States.

9,000+

Available grants

$2.61B

Total funding

$5K

Median grant

9,000+ grants
$2.61B total
$5K median

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9,423 Results based on applied filters

John H. Prescott Marine Mammal Rescue Assistance Grant (363929)

DOC NOAA - ERA Production
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The John H. Prescott Marine Mammal Rescue Assistance Grant supports the recovery and care of sick or injured marine mammals through federal assistance to the U.S. National Marine Mammal Stranding and Entanglement Response Networks. Eligible applicants must provide a Prescott Letter of Eligibility, confirming their participation in the network. This program aims to enhance marine mammal health monitoring and response capabilities across the country, ensuring timely and effective interventions for stranded marine life.
Wildlife Management Marine / Ocean Conservation Environmental Health

Broad Street Children's Foundation Grant

Broad Street Childrens Foundation
Private
United States
Unspecified amount

Who We Are

Broad Street Children's Foundation is committed to providing financial support to privately funded children's homes caring for the orphaned, abandoned and broken children right here in the United States.

Grant Seekers

Broad Street Children's Foundation supports self-sustaining children's homes across the United States that actively foster the development of strong, well-rounded children in their care.

Since the start of the Foundation, over $1,000,000.00 in grants have been donated to children's homes across the country. Additionally, through the Bill and Jackie Hazelgrove Scholarship Program, we have been able to assist a number of young people to continue their education and work towards a college or vocational degree.

Today, the Broad Street Children's Foundation is continuing the dream of it's original founders through the second generation. Equally as dedicated to changing the lives of children in need across America and striving to break the cycle of abuse and neglect for other children and their families.

Child Welfare Services Vocational & Trade Education Child Abuse & Neglect +2 more

Holloway Family Foundation Grant

Graham and Carolyn Holloway Family Foundation
Private
United States
Unspecified amount
The Holloway Family Foundation, established in North Central Texas, aims to enhance community quality of life regardless of race, gender, or religion. Their mission focuses on financial security, creative expression for under-resourced youth, and mentorship for personal development. The foundation supports organizations that provide workforce training, artistic opportunities for children, and guidance for youth in need. By fostering individual growth and economic stability, they empower families and strengthen communities, staying true to the founders' core values and personal experiences.
Tutoring & Mentoring Workforce Preparation & Job Readiness Youth Involvement in the Arts

Richard Beatty Mellon Environmental Stewardship Award

Air & Waste Management Association (A&WMA)
Association/Society
United States
Unspecified amount
The Richard Beatty Mellon Environmental Stewardship Award, established in 1954, honors individuals or organizations for significant contributions to pollution abatement. Eligible candidates demonstrate dedicated efforts in promoting air pollution control and waste management. This prestigious award reflects the legacy of Richard Beatty Mellon, who pioneered research in air quality and environmental protection. The award is open to both members and nonmembers of the Air & Waste Management Association.
Environmental Contamination & Pollution Environmental Stewardship Waste Management

Senator Harold “Potch” Wheeler Memorial Scholarship

Community Foundation of Whitley County
Association/Society
United States
Unspecified amount
The Senator Harold "Potch" Wheeler Memorial Scholarship, managed by the Community Foundation of Whitley County, honors the legacy of a dedicated public servant. This competitive scholarship is available annually to high school seniors from Whitley County who plan to pursue college education in public service or within the Indiana Department of Natural Resources. Recipients are chosen based on their embodiment of the ideals and character traits exemplified by Senator Wheeler.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Milton & Phyllis Berg Family Respite Care Grants

Alzheimers Foundation Of America Inc
Private
United States
US $6,000
The Milton & Phyllis Berg Family Respite Care Grants, offered by the Alzheimer’s Foundation of America, support member organizations in providing respite care scholarships to families affected by Alzheimer's. This initiative enhances the quality of life for both individuals and caregivers by promoting social engagement and offering essential breaks for caregivers. Grants are awarded biannually in memory of Barry E. Berg's parents, who faced Alzheimer's and caregiving challenges.
Dementia & Alzheimer’s Disease Caregiver Support / Respite Care

Phased Large Awards for Comparative Effectiveness Research PCORI Funding Announcement -- Cycle 1 2026

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $22,000,000
The Patient-Centered Outcomes Research Institute (PCORI) will announce the Phased Large Awards for Comparative Effectiveness Research on December 2, 2025. This funding aims to support high-quality, patient-centered comparative clinical effectiveness research projects. The initiative encourages applicants to engage with patients and stakeholders to address critical healthcare dilemmas and improve decision-making. Projects should compare established clinical alternatives with evidence of efficacy, targeting vital health issues across diverse populations.
Addiction & Substance Use Disorders Mental Health & Psychiatric Diseases Cardiovascular Diseases & Systems +2 more

NMDP Barbara Buchbinder Nurse Research Program Grant

National Marrow Donor Program
Private
United States
US $25,000
The NMDP Barbara Buchbinder Nurse Research Program Grant supports pediatric BMT nurses conducting research to enhance transplant experiences and outcomes for children. With only 4% of federal funding allocated to childhood cancer, this program, honoring a dedicated nurse, aims to attract new talent to the field. Each selected Buchbinder Scholar receives a $25,000 award to pursue relevant investigations, emphasizing the importance of supportive care in pediatric allogeneic hematopoietic cell transplants.
Children’s Health & Pediatrics Hematological Systems Cell Biology +1 more

Virginia Valk Fehsenfeld Scholarship

Grand Rapids Community Foundation
Private
United States
Unspecified amount

Generally the Community Foundation's scholarships are awarded to applicants who have high financial need. Applicants with household income exceeding $100,000 are less likely to be awarded, but applying will allow you to be considered for targeted scholarships.

Virginia Valk Fehsenfeld Scholarship

Open to full time undergraduate students who are Kent County residents studying education, dietetics, nutrition, or human services and have a minimum 3.4 GPA.

Education Teacher Development & Training Education - High School +2 more

Ryan White HIV/AIDS Program Part B States/Territories Supplemental Grant Program (363163)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $9,000,000
The Ryan White HIV/AIDS Program Part B Supplemental Grant aims to provide essential funding to support HIV care and treatment services across states and territories. This program supplements existing formula-based funding from the RWHAP Part B and ADAP, improving access to necessary resources for those affected by HIV/AIDS. By enhancing support structures, it addresses critical healthcare needs, ensuring better health outcomes for vulnerable populations.
HIV / AIDS

HIV Care Grant Program - Part B States/Territories Formula and AIDS Drug Assistance Program Formula and AIDS Drug Assistance Program Supplemental Awards

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The HIV Care Grant Program, funded by the US HHS: Health Resources & Services Administration (HRSA), aims to enhance access to high-quality HIV care and treatment for low-income individuals. This initiative supports states and territories in developing comprehensive systems to address the needs of those living with HIV. By providing essential resources, the program seeks to improve health outcomes and ensure that vulnerable populations receive the necessary support and services.
HIV / AIDS

Harry Kramer Memorial Fund Grant

Harry Kramer Memorial Fund
Private
Israel, United States
US $10,000 - US $25,000
The Harry Kramer Memorial Fund Grant supports U.S. charitable organizations that assist individuals and institutions in Israel, focusing on welfare, healthcare for the sick and aged, and education in South Florida. Founded by Harry A. Kramer, a successful entrepreneur and veteran, the fund reflects his deep commitment to charitable causes. Organizations must qualify under Section 501(c)(3) and meet specific eligibility criteria to apply for funding, ensuring that aid reaches those in need.
Jewish Culture Senior Services Religion & Spirituality +4 more

Corporate Giving - Charitable Contributions

McCormick & Company, Inc
Corporate
United States
Unspecified amount
McCormick & Company, Inc. actively supports charitable contributions through its Charitable Donations Committee (CDC), which prioritizes donations to non-profit organizations that enhance education, health, environment, and culture. The CDC focuses on organizations that benefit communities where McCormick employees live and work, ensuring a positive impact. Eligible groups must be tax-exempt and demonstrate a commitment to non-discrimination. However, donations are not made to individuals, political organizations, or entities that conflict with corporate values.
Environment Art & Culture Health & Medicine +4 more

The Save Mart Companies CARES Foundation Grant

Save Mart Cares
Private
California, Oregon +2 more
US $500 - US $10,000

About

With deep roots in California’s Central Valley, The Save Mart Companies and its family of stores prides itself in being a part of neighborhoods and putting people first. Our dedication to customers is reflected in the connections we’ve made in the communities we’ve served for more than 70 years.

The Save Mart Companies CARES Foundation

In 2000, we established The Save Mart Companies CARES Foundation, our philanthropic, non-profit organization, supporting programs and organizations that provide vital resources for children and families in the communities we serve. The CARES Foundation focuses on building stronger communities through fresh foods, accessibility, and programs that support youth and helping them to thrive. Annually, The CARES Foundation contributes approximately $500,000 in small grants to support community-based, non-profit organizations.

The Save Mart Companies CARES Foundation Grant

The CARES Foundation’s focus is building stronger communities through fresh foods, access to food, and programs that support youth and helping them thrive.

The CARES Foundation will review, on a quarterly basis, among other things, the breadth of the audience served; the likely impact in the community; the importance of the need to be addressed in the community; and the community reputation, service history, and financial stability of the group or program seeking funds. No one of these or other factors will necessarily be weighted more heavily than another. Instead, each group or program will be measured against all groups and 2 programs seeking funding at the time. For example, a program serving a small segment of the community but that addresses an especially important community need, and thus has the potential for a strong and meaningful impact, would be favored over a group serving a wider clientele but that fills a less important community need. Requests for Grants should be a minimum of $500.00 up to $10,000.00. Programs and organizations requesting smaller grants should contact the Store Manager of the nearest Save Mart Companies’ store location for request consideration.

Recipients that receive grants for more than one year must demonstrate meaningful outcomes for the previous investment made by The CARES Foundation.

Food Access & Hunger Youth Services Family Services +1 more

NIAMS Clinical Trial Implementation Cooperative Agreement

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
More than US $250,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is inviting applications for the Clinical Trial Cooperative Agreement Program. This funding opportunity supports investigator-initiated, interventional clinical trials at various phases. Initial funding will facilitate the preparation needed to start trials, with successful milestones leading to further support. NIAMS emphasizes hypothesis-driven trials that promise significant clinical impact within its research mission.
Musculoskeletal Diseases Arthritis Skin Diseases & Dermatology

Guidelines to Develop Best-In-Class Maintenance Strategies for Vertical Assets RFP

Water Research Foundation
Private
Countries
Up to US $250,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5415 - Guidelines to Develop Best-In-Class Maintenance Strategies for Vertical Assets

Grant Information

  • Develop a clear understanding of the background and benefits associated with implementing well-rounded maintenance strategies for vertical assets.
  • Develop a structured approach to identify and implement best-in-class maintenance strategies for vertical assets that improve reliability, increase asset availability, reduce unplanned work and emergency shutdowns, support the transition from reactive to proactive maintenance, and minimize total lifecycle cost.
  • Apply leading practices such as Reliability Centered Maintenance (RCM) and cutting-edge technologies and analytics to vertical assets.
Water Resource Management

Summer Food Service Program (SUN) program 2026

Islamic Relief Usa
Private
United States
Unspecified amount

A funding opportunity designed to support food security, refugee services, licensed free healthcare clinics and community development organizations in the United States.

Summer Food Service Program (SUN) program 2026

The Summer Food Service Program (SUN), created and funded by the United States Department of Agriculture (USDA), currently provides organizations with limited funding opportunities to purchase and provide meals to their local communities in the form of reimbursements. Starting in 2011, IRUSA began to supplement and support the USDA in this effort. SUN recipient, organizations are able to start a USDA-approved site, increase the capacity of their current USDA-approved site(s) or develop their role as the meal-providing sponsor to subgrantees. Grants are provided to further enable and encourage wider participation in this program as well as increase food access and support to food-insecure children throughout the summer months. 

Food Security Food Delivery & Distribution Services

Improved Drug Susceptibility Testing (DST) for Mycobacteria

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.
Infectious & Parasitic Diseases Tuberculosis Drug-Resistant Bacteria

AHRF Discovery Grants

American Hearing Research Foundation
Private
United States
Up to US $50,000
The AHRF Discovery Grants support innovative research on hearing and balance disorders, offering up to $50,000 for one year. Targeting early-career investigators, these grants aim to generate preliminary data for larger funding applications. Special consideration is given to projects exploring Meniere's disease and sudden hearing loss. Grants cover direct research costs, excluding principal investigator salaries and indirect expenses. The initiative strives to fund promising studies that can advance our understanding of auditory and vestibular health.
Hearing Disorders & Audiology Meniere’s Disease

National Trappers Foundation Grants

National Trappers Foundation
Association/Society
United States
Unspecified amount
The National Trappers Foundation (NTF) offers grants to individuals and organizations for projects related to furbearers. Founded in 1988, NTF supports educational and conservation initiatives that promote the management and restoration of furbearers and natural resources. Grants are available for research, habitat development, and educational programs. Contributions to NTF are tax-deductible, reflecting its commitment to conservation and community engagement.
Mammalogy

Incyte: Healthcare-related Charitable Contributions, Sponsorship and Membership Requests

Incyte Corporation
Corporate
United States
Unspecified amount
Incyte Corporation invites organizations to submit membership requests aimed at enhancing healthcare access for patients and advocates. As a biopharmaceutical leader, Incyte supports initiatives that align with its mission to improve patient lives through grants and contributions. Eligible entities include medical schools, associations, non-profits, and advocacy groups. Requests should comply with Incyte's regulatory standards and be submitted at least 60 days prior to the required decision date.
Cancer / Oncology Diseases & Conditions Nursing +2 more

Incyte Healthcare Sponsorships

Incyte Corporation
Corporate
United States
Unspecified amount
Incyte Corporation, a biopharmaceutical leader, offers healthcare sponsorships to support organizations focused on improving patient care and access to healthcare information. Eligible applicants include medical schools, associations, non-profits, advocacy groups, and hospitals. Requests should align with Incyte's commitment to enhancing the lives of patients affected by cancer and other diseases, ensuring compliance with regulatory guidelines. Organizations must enter a written agreement with Incyte to receive funding.
Cancer / Oncology Diseases & Conditions Nursing +2 more

Demonstration Projects for Whole-Person Health Models for Women Living with HIV in the South

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +7 more
Unspecified amount
This project aims to enhance health outcomes for women living with HIV in the South by integrating HIV care with comprehensive women's health services through coordinated Clinic and Community Collaboratives. By funding organizations to implement targeted strategies such as culturally responsive services and learning collaboratives, the initiative seeks to improve access to essential health services, increase the number of women initiating rapid ART, and foster sustainable healthcare models that address the unique needs of this population.
HIV / AIDS

Elizabeth Pastor Ashland University Music Education Scholarship

Ashland County Community Foundation
Private
United States
Unspecified amount
The Elizabeth Pastor Ashland University Music Education Scholarship supports music students at Ashland University, honoring the legacy of Elizabeth Pastor, a renowned pianist and educator. This scholarship aims to assist students pursuing a music-related career, reflecting Pastor's belief in the transformative power of art. Established through her estate plan, it embodies her commitment to fostering musical talent and enriching the community through education and the arts.
Education - Higher Education Academic Scholarship Programs Music Education +2 more

AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional) (362945)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Mental Health is inviting research applications for the AIDS Research Center program, which includes Developmental Centers and full Research Centers. This initiative aims to enhance interdisciplinary HIV/AIDS research through collaboration and innovative approaches across various scientific domains. The program emphasizes alignment with national strategies and encourages applications from teams skilled in fostering partnerships with diverse stakeholders. Although applications are currently not being solicited, this notice allows potential applicants time to prepare strong proposals.
HIV / AIDS

Scaling Pathways to Homeownership

Capital One Foundation
Corporate
American Samoa, Guam +4 more
US $200,000
  • Innovative: An approach that brings fresh thinking, tools, or models to homeownership in ways that challenge the status quo and demonstrate a disruptive, future-oriented vision with potential to inspire or shift broader field practice.
  • Impactful: A solution with meaningful potential to expand homeownership through knowledge and action, featuring clear and measurable progress indicators that demonstrate capacity to shift trajectories for low- and moderate-income households.
  • Bridge-Building: An initiative that effectively connects and unifies a wide range of stakeholders, fostering meaningful collaboration across sectors or perspectives. The strongest submissions will reflect strong community partnerships across the housing ecosystem.
  • Durable: A sustainable pathway that addresses root causes of homeownership barriers rather than just symptoms, with compelling evidence of potential to elicit robust support from broad private, philanthropic, and public funding sources over time.
Homeownership Equitable & Affordable Housing

Scleroderma-Related Lung Disease— The Debra Lurvey Memorial Research Grant

National Scleroderma Foundation
Private
United States
US $200,000
The Scleroderma-Related Lung Disease— The Debra Lurvey Memorial Research Grant, provided by the National Scleroderma Foundation, aims to support research in scleroderma-related lung disease. With a funding amount of $200,000, the grant encourages established investigators to explore innovative solutions and enhance understanding of this condition, ultimately working towards improving the quality of life for affected individuals and advancing medical knowledge in the field.
Rare Diseases Immune System Diseases Interstitial Lung Disease

Large Grants for Nonprofit Organizations in Kentucky Highlights

Looking for large grants for nonprofit organizations in Kentucky?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Kentucky recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Kentucky

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Large Grants for Nonprofit Organizations in Kentucky grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

30 Large Grants for Nonprofit Organizations in Kentucky over $25K in average grant size

21 Large Grants for Nonprofit Organizations in Kentucky over $50K in average grant size

22 Large Grants for Nonprofit Organizations in Kentucky supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in Kentucky supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

400+ Grants on Instrumentl focused on Disaster Relief / Humanitarian Aid

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Kentucky?

Most grants are due in the first quarter.

Q1
33.9%
Q2
21.2%
Q3
23.7%
Q4
21.2%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Kentucky?

Grants are most commonly $8,000.

$500 $500 Min.
$8,000 $8 K Median
$711,767 $711.8 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Kentucky?

Grants are most commonly $109,567.

$109,567

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Kentucky year over year?

In 2024, funders in Kentucky awarded a total of 22,947 grants.

2022 21,785

2023 21,128

2024 22,947

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Kentucky given out in Kentucky, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Kentucky changing over time?

Funding has increased by -8.86%.

2022 $1,911,078,212

2023 $2,749,886,359
43.89%

2024 $2,506,220,272
-8.86%

Kentucky Counties That Receive the Most Funding

How does grant funding vary by county?

Jefferson County, Kenton County, and Fayette County receive the most funding.

County Total Grant Funding in 2024
Jefferson County $2,891,811,659
Kenton County $622,235,633
Fayette County $177,080,873
Madison County $78,275,790
Whitley County $69,351,226