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Best Large Grants for Nonprofit Organizations in Kentucky

Find the perfect Large Grants for Nonprofit Organizations in Kentucky on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in Kentucky in the United States.

9,000+

Available grants

$2.61B

Total funding

$5K

Median grant

9,000+ grants
$2.61B total
$5K median

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9,423 Results based on applied filters

Herold and Retta Reuss Public Safety Scholarship

Marshall Community Foundation
Private
United States
Unspecified amount

Herold and Retta Reuss Public Safety Scholarship

Applicants must demonstrate the drive and ability to be successful in pursuing a college education and/or a certification process in the fields aforementioned. Financial information is requested, but not necessarily a determining factor. Students who receive this scholarship may apply for further support in subsequent years.

Education - Higher Education Crime & Justice Career / College Preparation +2 more

Providers Clinical Support System – Universities

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Providers Clinical Support System – Universities program aims to equip graduate-level health professional students with the necessary skills to understand, identify, intervene, and treat patients with substance use disorders. By focusing on practical training and comprehensive education, this initiative prepares future practitioners to effectively address the challenges associated with substance misuse, ensuring they are well-prepared upon obtaining their licenses.
Education - Higher Education Workforce Preparation & Job Readiness Addiction & Substance Use Disorders +1 more

Judith Heavenrich Memorial Scholarship

Saginaw Community Foundation
Private
United States
US $500 - US $4,000
The Judith Heavenrich Memorial Scholarship, established in memory of Judith Heavenrich, aims to support single, low-income mothers in Saginaw County as they pursue higher education or vocational training. Judith, a lifelong advocate for education and environmental issues, faced numerous challenges in her life but remained dedicated to her community. This scholarship reflects her spirit and commitment to empowering women to achieve their educational goals, with awards typically ranging from $500 to $4,000.
Education - Higher Education Education - High School Academic Scholarship Programs +3 more

Fish Family Foundation of Maine Grants

Fish Family Foundation of Maine
Private
United States
Unspecified amount

Mission

The Fish Family Foundation of Maine is a faith based charitable organization located in Bangor, Maine. Founded in 2007, our mission is to provide resources for many initiatives including, but not limited to, missions, education scholarships, ministries, medical research, and employment creation. The Fish Family Foundation of Maine is primarily funded by the family. However, contributions from like minded individuals and organizations is appreciated. The Fish Family Foundation of Maine has a balanced strategy of making funds available for immediate needs, while also investing to build a perpetual earning endowment ensuring the Foundation's successful future.

Missions:

We support needs of missionary organizations including sponsorships for young people who wish to attend youth group sponsored mission trips. We ordinarily make one time contributions but on occasion have made up to a three year commitment. 

Education/Scholarships:

The Foundation makes scholarships available to Colleges, Universities, and other Schools for student enrollment and expenses. We also consider new construction, existing renovation, equipment, and support material contributions.

Independent Churches and Ministries:

We accept a wide variety of requests, including, but not limited to: materials, equipment, new construction, renovations, programs, and services. 

Medical Research:

We support medical research opportunities close to our hearts and organizations that our family and friends have experienced. 

Job Creation:

We Support organizations that fund entrepreneurs in impoverished areas to start small businesses providing services and employment to the community.

Requests are considered by the trustees the first week of each month. Foundation payments are made by paper check in US dollars and are reported to the appropriate tax agencies. While we certainly wish that we could contribute to all the applications that meet our funding criteria, there are times when when available funding is limited and we are not able to contribute to some very worthy causes. If we are not in a position to help in the timeline requested, we will keep the information on file for possible consideration in the future. 

Volunteerism & Philanthropy Academic Scholarship Programs Education +3 more

NPS Cooperative Ecosystems Studies Units (CESU) Master Cooperative Agreements

US Department of the Interior: National Park Service (NPS)
Federal Government
United States
Unspecified amount
The National Park Service (NPS) invites applications for Master Cooperative Agreements from participants in the Cooperative Ecosystem Studies Units (CESU) network across various regions. This initiative fosters collaboration among federal agencies, tribes, academic institutions, and conservation organizations to enhance resource stewardship. With 390 non-federal partners and 15 federal agencies, the CESU network supports interdisciplinary projects addressing diverse environmental and cultural heritage issues. Applications are continually accepted until the announcement's closing date.
Environmental Conservation Natural Resources Ecology

Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional) (357667)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $3,250,000
The Limited Competition: Clinical and Translational Science Award (CTSA) Program's Collaborative and Innovative Acceleration Award aims to enhance translational research by fostering collaboration in developing and implementing innovative solutions. This funding opportunity invites applications focused on new approaches and technologies that will improve research impact across various diseases and expedite treatment availability. Eligible applicants include organizations with active CTSA hub prime or partnering awards.
Health & Medicine Pharmacology Biomedical informatics +4 more

Emerging Leaders Program Alumni Award

Soil and Water Conservation Society (SWCS)
Association/Society
United States
US $500

About Us

The Soil and Water Conservation Society (SWCS) is the premier international organization for professionals who practice and advance the science and art of natural resource conservation.

SWCS Emerging Leaders Program Alumni Award

The Emerging Leader Alumni Award recognizes outstanding alumni of the Emerging Leaders Program (ELP) who have demonstrated a commitment to conservation leadership and active participation in the Soil and Water Conservation Society (SWCS). Three $500 cash awards will be granted to support professional development, Society membership, conference fees, or other career-enhancing opportunities.

Freshwater Conservation Green Infrastructure Civic Leadership Development

Les Paul Foundation Grant

Les Paul Foundation
Private
United States
US $1,500 - US $2,000
The Les Paul Foundation Grant supports innovative music education and medical research related to hearing loss. Eligible organizations must be U.S.-based public charities under 501(c)(3) and avoid religious, political, labor, or business affiliations. The foundation prioritizes projects that enhance music production, performance, and STEM/STEAM initiatives, particularly those benefiting individuals in challenging situations. Proposals must detail how they will share Les Paul's legacy in their work.
Music Education STEM / STEAM Education Hearing Disorders & Audiology

C.V Glassco Memorial Scholarship Fund

Community Foundation of Northeast Alabama
Private
United States
Unspecified amount
The C.V. Glassco Memorial Scholarship Fund honors Mr. Clarence Verbal Glassco, a dedicated community volunteer and veteran. This scholarship supports full-time students pursuing higher education or approved workforce training in Alabama. Funded by the Community Foundation of Northeast Alabama, it covers tuition, housing, and books based on available assets. Applicants are encouraged to seek additional financial resources. This initiative preserves Mr. Glassco's legacy of service and commitment to education.
Civic Leadership Development Academic Scholarship Programs Education - Higher Education +1 more

Erin Marie Masling Memorial Scholarship

Rochester Area Community Foundation
Private
United States
More than US $500

Erin Marie Masling Memorial Scholarship

This scholarship encourages students who have the potential and desire to pursue a post-secondary education despite the effects of an ongoing medical condition or illness.

Number and Size of Awards

Number of recipients and award amounts vary; minimum award $500. Award paid in one lump sum in the Fall and divided equally between the Fall and Spring semesters.

Allowed Use of Award

Awards may be used for tuition, fees, books, and other expenses associated with higher education.

Education - Higher Education Cystic Fibrosis Chronic Illnesses

PERF: CNS Bridge Grant Program

Pediatric Epilepsy Research Foundation
Private
Canada, United States
Up to US $100,000
The PERF: CNS Bridge Grant Program aims to support emerging child neurology researchers by providing essential bridge funding while they seek independent research grants from NIH or CIHR. Established by the Pediatric Epilepsy Research Foundation in collaboration with the Child Neurology Society, this initiative seeks to retain talented investigators in the field of pediatric neurology. Since its inception, the foundation has awarded over $18 million to advance pediatric epilepsy research and related conditions.
Children’s Health & Pediatrics Neuroscience Epilepsy

Rural Communities Opioid Response Program - Evaluation

Health Resources and Services Administration
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The Rural Communities Opioid Response Program - Evaluation aims to assess the effectiveness of behavioral health strategies in rural settings. By developing evaluation tools and resources, this initiative seeks to empower local communities in their health initiatives, ensuring that future programs are informed by comprehensive evaluations. Funded by the Health Resources and Services Administration, the program highlights the importance of tailored approaches to address opioid-related challenges in rural areas.
Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders Rural Development +1 more

GLLCF Nursing Scholarship

Greater Lake City Community Foundation
Corporate
United States
Unspecified amount

About

Created by the community for the good of the community, the GLCCF is here to turn problems into opportunities through strategic grant making and initiatives created to address our region’s most pressing needs. We work with you to identify your charitable goals, and we ensure that they are carried out efficiently.

Work with us to make the kind of impact you want to see in your community. Let us take on the financial complexities and paperwork, while you focus on the important things like fostering good works throughout our community.

When you give to the Greater Lake City Community Foundation, you are making an investment that will benefit the community, now and in the future.

GLLCF Nursing Scholarship

To award annually a scholarship to a qualified applicant who intends to further his/her education toward a degree in nursing.

Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Ralph W. Shrader Graduate Scholarship in Communications and Electronics

AFCEA
Association/Society
United States
US $3,000
The Ralph W. Shrader Graduate Scholarship offers $3,000 to full-time graduate students in STEM-related fields at accredited U.S. institutions. Applicants must be U.S. citizens, enrolled in their second semester, and maintain a GPA of 3.5 or higher. The scholarship supports tuition and course-related expenses, encouraging students with financial needs to further their education. Notably, the expected graduation date cannot coincide with the award year, ensuring students are committed to their studies.
Geoinformatics & Geospatial Sciences Mathematics Physics +8 more

Multiplex Platforms to Assess Indicators of Micronutrient Status, Inflammation and Infectious Disease Grant (Minimum Scope)

Gates Foundation
Private
Countries
Up to US $200,000

Multiplex Platforms to Assess Indicators of Micronutrient Status, Inflammation and Infectious Disease

The Challenge

Although combined immunological measurement of several micronutrient biomarkers has been demonstrated, current methods still have important limitations. These include heterogeneity in the composition of standards and controls; inconsistent batch-to-batch performance of analyte-binding molecules; variable reactivity for some analytes, especially soluble transferrin receptor (sTfR); and a functional analytical range that is too narrow to cover the physiological values of some analytes, such as CRP. It would also be valuable to add bioindicators for vitamins B1, B2, B9 and B12, which may require binding molecules that recognize metabolites or proteins associated with deficiency, a specific vitamer (plasma methyl-tetrahydrofolate without reacting with folic acid), comparable reactivity across vitamers (several folate forms in red blood cells), or a specific carrier-protein form (holo-transcobalamin rather than apo-transcobalamin or haptocorrin for vitamin B12).

The improved assays must combine high analytical specificity, sensitivity and robustness with a functional analytical range matched to the physiological values expected in the target populations (women of reproductive age, including during pregnancy and lactation, preschool-age children and older adults). Assays must remain low-cost (no more than US$20 for all analytes measured in duplicate) and require very small sample volumes, preferably less than 10 µL of plasma or serum). The tests are intended for population surveillance rather than local clinical (point-of-care) use. They should be designed to run many samples in a single batch in a small number of national or regional reference laboratories. The goal is to reduce dependence on expensive, infrequent population surveys and on export of samples to specialized laboratories in high-income settings.

This challenge is structured around two alternatives, a minimum-scope approach and an optimistic-scope approach. Targets are aligned with the candidate Target Product Profile for this platform, and applicants will be held to the relevant performance, cost and instrument targets.

Epidemiology & Public Health Biochemistry Infectious & Parasitic Diseases +2 more

Tim and Sharon (Hemmeter) Buren Scholarship

Ashland County Community Foundation
Private
United States
Unspecified amount
The Tim and Sharon (Hemmeter) Buren Scholarship, managed by the Ashland County Community Foundation, supports graduating seniors and current students from Mapleton or Northwestern high schools. Eligible applicants must maintain a GPA of 3.0 and gain acceptance to an accredited college or vocational school. This scholarship encourages educational advancement, providing crucial financial assistance to both traditional and non-traditional students, thereby contributing to the community's future prosperity.
Education - Higher Education Career / College Preparation Education - High School +2 more

Dr. Chao-ying & Sue Wu Early Learning Scholarship

Chuckanut Health Foundation
Private
United States
Unspecified amount
The Dr. Chao-ying & Sue Wu Early Learning Scholarship, established by the Chuckanut Health Foundation in 2022, honors the vital contributions of Dr. Chao-ying and Sue Wu to the health and education of Whatcom youth. This scholarship aims to eliminate financial barriers for local students pursuing careers in early learning, reflecting the Foundation's commitment to investing in community potential and fostering opportunities for future generations.
Education - Higher Education Academic Scholarship Programs Youth Services +3 more

Multiplex Platforms to Assess Indicators of Micronutrient Status, Inflammation and Infectious Disease Grant (Optimistic Scope)

Gates Foundation
Private
Countries
Up to US $800,000

Multiplex Platforms to Assess Indicators of Micronutrient Status, Inflammation and Infectious Disease

The Challenge

Although combined immunological measurement of several micronutrient biomarkers has been demonstrated, current methods still have important limitations. These include heterogeneity in the composition of standards and controls; inconsistent batch-to-batch performance of analyte-binding molecules; variable reactivity for some analytes, especially soluble transferrin receptor (sTfR); and a functional analytical range that is too narrow to cover the physiological values of some analytes, such as CRP. It would also be valuable to add bioindicators for vitamins B1, B2, B9 and B12, which may require binding molecules that recognize metabolites or proteins associated with deficiency, a specific vitamer (plasma methyl-tetrahydrofolate without reacting with folic acid), comparable reactivity across vitamers (several folate forms in red blood cells), or a specific carrier-protein form (holo-transcobalamin rather than apo-transcobalamin or haptocorrin for vitamin B12).

The improved assays must combine high analytical specificity, sensitivity and robustness with a functional analytical range matched to the physiological values expected in the target populations (women of reproductive age, including during pregnancy and lactation, preschool-age children and older adults). Assays must remain low-cost (no more than US$20 for all analytes measured in duplicate) and require very small sample volumes, preferably less than 10 µL of plasma or serum). The tests are intended for population surveillance rather than local clinical (point-of-care) use. They should be designed to run many samples in a single batch in a small number of national or regional reference laboratories. The goal is to reduce dependence on expensive, infrequent population surveys and on export of samples to specialized laboratories in high-income settings.

This challenge is structured around two alternatives, a minimum-scope approach and an optimistic-scope approach. Targets are aligned with the candidate Target Product Profile for this platform, and applicants will be held to the relevant performance, cost and instrument targets.

Epidemiology & Public Health Biochemistry Infectious & Parasitic Diseases +2 more

BAE Systems: Community investment Grants

BAE Systems
Corporate
Aiken County, South Carolina, Allegheny County, Pennsylvania +78 more
Unspecified amount
BAE Systems offers community investment grants aimed at enhancing the well-being of military families and supporting future workforce development in STEM fields. As a U.S. subsidiary of a global defense and aerospace leader, they require applicants to be recognized 501(c) organizations. The initiative underscores a commitment to charitable partnerships that uplift local communities and contribute positively to society.
Military Operations Military & Veterans Services Education - Preschool / Early Learning +3 more

Parkinson Family Foundation Grant

Parkinson Family Foundation
Private
United States
US $1,000 - US $5,000
The Parkinson Family Foundation Grant supports organizations focusing on Food & Water, Faith & Evangelism, and Health & Humanitarian Efforts. Applications are open year-round, with grants ranging from $1,000 to $5,000; larger requests are typically declined. Eligible applicants include schools, state governments, and 501(c)(3) nonprofits. The Foundation emphasizes selectivity and prioritizes organizations with established relationships and those promoting American ideals like freedom and justice.
Food Access & Hunger Sanitation & Clean Drinking Water Disaster Relief / Humanitarian Aid +2 more

Robert W. and Martha D. Casciani Scholarship

Ashland County Community Foundation
Private
United States
Unspecified amount
The Robert W. and Martha D. Casciani Scholarship, managed by the Ashland County Community Foundation, supports graduating seniors from Ashland County high schools who have a GPA of 3.0 or higher and are pursuing degrees in Chemical or Mechanical Engineering at accredited colleges outside the county. This scholarship honors the legacy of Robert and Martha Casciani, who were committed to their community and education, encouraging future generations to achieve their academic goals.
Education - Higher Education Career / College Preparation Education - High School +3 more

Delta Workforce Grant Program

Delta Regional Authority
Federal Government
Acadia Parish, Louisiana, Adams County, Mississippi +250 more
US $50,000 - US $300,000

Delta Workforce Grant Program

The Delta Workforce Grant Program (DWP) is an initiative designed to build long-term community capacity and increase economic competitiveness by providing grants to support workforce training and education programs throughout the lower Mississippi River Delta and Alabama Black Belt regions.

DWP supports projects and initiatives that create a more vibrant economic future for the Delta region by expanding opportunities to recruit, train, and retain a diverse and local workforce; aligning workforce and economic development strategies; creating sustainable talent pipelines; establishing or enhancing locally/regionally significant sector-based partnerships; and supporting enhanced workforce productivity through investments in innovative programming or services.

Workforce Preparation & Job Readiness Economic Services & Development Career / College Preparation

Thompson Charitable Foundation Grants

The Thompson Charitable Foundation
Private
Anderson County, Tennessee, Bell County, Kentucky +8 more
Unspecified amount
The Thompson Charitable Foundation, established in 1987, aims to enhance the quality of life for communities in Kentucky, Tennessee, and Virginia. It focuses on funding nonprofit projects in health services, education, and community development. Grants are available for matching funds and capital projects but do not support endowments or religious activities. Preference is given to applicants previously funded by TCF. Interested organizations must submit a Letter of Inquiry before the application deadline.
Health & Medicine Human & Social Services Education +3 more

Measurement and Evaluation Lifetime Achievement Award

Society Of Health And Physical Educators
Private
United States
Unspecified amount
The Measurement and Evaluation Lifetime Achievement Award recognizes a distinguished SHAPE America professional who has significantly impacted measurement and evaluation in health and physical education. This prestigious award highlights the importance of scholarly achievement and the influence of national standards in enhancing educational practices. It aims to honor those who have dedicated their careers to improving the quality of health and physical education, ultimately promoting healthier lifestyles for students across the nation.
Kinesiology & Sports Medicine Education - K through 12 Dance +2 more

Emergency Citrus Disease Research and Extension Pre-Applications

USDA: National Institute of Food and Agriculture (NIFA)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $15,000,000
The Emergency Citrus Disease Research and Extension Pre-Applications program, funded by the USDA's National Institute of Food and Agriculture, seeks innovative proposals to combat Huanglongbing (HLB) and its associated diseases. This initiative aims to ensure sustainable citrus production in the U.S. through collaborative strategies that leverage existing knowledge. Funded projects will focus on developing actionable solutions for growers to effectively manage and prevent HLB infections, ensuring the health of citrus crops in the near future.
Agriculture Agricultural Crops Sustainable Agriculture & Agroecology +1 more

NAFC Patient Care Fund

National Association of Free and Charitable Clinics Inc
Private
United States
US $20,000

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Patient Care Fund

The NAFC Patient Care Fund supports direct patient services that expand immediate access to care. This funding is designed to help NAFC members meet urgent patient needs by supporting clinical supplies, expanded services, contracted providers, transportation assistance, medication access, and other direct care resources.

Patient Care & Services Health Care Access & Delivery Health Facilities & Clinics +1 more

HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HEAL Initiative aims to address the significant overlap between chronic pain (CP) and opioid use disorder (OUD), with 40-75% of individuals affected by both. The IMPOWR project focuses on testing innovative interventions and implementation strategies to integrate care for CP and OUD across various health systems. The BEACON Center will enhance network coordination, build capacity, and develop resources to address barriers in service delivery, ultimately improving sustainability and scalability of evidence-based practices.
Epidemiology & Public Health Addiction & Substance Use Disorders Health Care Access & Delivery +2 more

Large Grants for Nonprofit Organizations in Kentucky Highlights

Looking for large grants for nonprofit organizations in Kentucky?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Kentucky recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Kentucky

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Large Grants for Nonprofit Organizations in Kentucky grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

30 Large Grants for Nonprofit Organizations in Kentucky over $25K in average grant size

21 Large Grants for Nonprofit Organizations in Kentucky over $50K in average grant size

22 Large Grants for Nonprofit Organizations in Kentucky supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in Kentucky supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

400+ Grants on Instrumentl focused on Disaster Relief / Humanitarian Aid

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Kentucky?

Most grants are due in the first quarter.

Q1
33.9%
Q2
21.2%
Q3
23.7%
Q4
21.2%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Kentucky?

Grants are most commonly $8,000.

$500 $500 Min.
$8,000 $8 K Median
$711,767 $711.8 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Kentucky?

Grants are most commonly $109,567.

$109,567

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Kentucky year over year?

In 2024, funders in Kentucky awarded a total of 22,947 grants.

2022 21,785

2023 21,128

2024 22,947

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Kentucky given out in Kentucky, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Kentucky changing over time?

Funding has increased by -8.86%.

2022 $1,911,078,212

2023 $2,749,886,359
43.89%

2024 $2,506,220,272
-8.86%

Kentucky Counties That Receive the Most Funding

How does grant funding vary by county?

Jefferson County, Kenton County, and Fayette County receive the most funding.

County Total Grant Funding in 2024
Jefferson County $2,891,811,659
Kenton County $622,235,633
Fayette County $177,080,873
Madison County $78,275,790
Whitley County $69,351,226