Best Large Grants for Nonprofit Organizations in Kentucky

The NIH Countermeasures Against Chemical Threats (CounterACT) initiative invites applications for basic research on chemical agents affecting the nervous system. This program aims to explore the toxicity mechanisms of chemical warfare agents, industrial chemicals, and pesticides. Researchers are encouraged to generate data that could reveal new therapeutic targets and manifestations of toxic exposures, contributing to public health safety against potential chemical threats.

The AACR June L. Biedler Prize for Cancer Journalism

Prize Summary

The AACR June L. Biedler Prize for Cancer Journalism was established by the AACR in 2015 to raise awareness of the critical role that the media play in educating the public about cancer and cancer research.

Funded by a major bequest to the AACR from cancer research pioneer Dr. June L. Biedler, a scientist, mentor, and former member of the AACR Board of Directors, this prize showcases outstanding examples of cancer journalism and recognizes individual professional journalists who have produced accurate, informative, and compelling stories that enhance the public’s understanding of cancer, cancer research, cancer advocacy, or cancer policy.

The prize provides an unrestricted cash award of $5,000 and a commemorative award.

Categories

Each submission may be considered for only one category, as selected by the candidate on the application form.

Applicants may submit in any of the following categories:

Prize Acceptance

Awardees will be able to accept the prize during the AACR Annual Meeting 2027 in Orlando, April 2-7, 2027.

The California Specialty Crop Multi-State Program, established by the California Department of Food and Agriculture, aims to enhance the competitiveness of specialty crops through funding collaborative projects addressing key issues like food safety and marketing. Grants range from $250,000 to $1 million, supporting initiatives that span up to three years. This program emphasizes the importance of specialty crops, including fruits, vegetables, and horticulture, in California's agricultural landscape.

The BioMarin Grant aims to support events, activities, and projects that enhance public health and benefit patients with rare diseases. This corporate funder focuses on scientific innovation and provides resources for organizations such as hospitals, universities, and patient advocacy groups. With an emphasis on education and community support, BioMarin encourages applications for funding throughout the year, ensuring timely assistance for eligible projects.

The Perry L. McCarty AEESP Founders' Award, presented by the AEESP Foundation, honors outstanding contributions to environmental engineering education and research. It recognizes a professor's excellence in these fields, offering a plaque, a $1500 cash prize, and a $750 travel allotment for the awards ceremony. Nominations are accepted annually, with past submissions considered for three years. Careful adherence to nomination guidelines is essential for eligibility.

The Steven K. Dentel AEESP Award for Global Outreach recognizes faculty excellence in environmental engineering outreach. This annual award honors individuals who significantly contribute to global community health through education, research, and mentorship. Recipients receive a $500 cash award and a plaque. Nominations from students are welcomed, and past nominations can be modified within three years. This award aims to highlight sustained leadership and service in the environmental engineering field.

The Woman's National Farm and Garden Association (WNF&GA) Scholarship supports graduate students pursuing careers in conservation and natural resource management. This annual scholarship aims to continue the legacy of conservationists dedicated to protecting our planet's resources. Eligible candidates must demonstrate a strong commitment to environmental stewardship through their academic and community involvement. However, WNF&GA members and their immediate families are excluded from eligibility. The scholarship is a vital resource for future leaders in conservation.

Conserving Black Modernism Grant Program

The African American Cultural Heritage Action Fund (AACHAF), a program of the National Trust for Historic Preservation, has launched the Conserving Black Modernism grant program through funding from and a partnership with the Getty Foundation’s Keeping it Modern initiative. The Conserving Black Modernism grant program is designed to empower and equip preservationists and stewards with funding and technical support to preserve the material heritage, innovation, and legacy of modern architectural sites designed by Black architects.

Integrated into the Action Fund’s existing National Grant Program, the Conserving Black Modernism grant program will support non-profits and municipalities to steward 16 historic assets of modern architecture through funding, technical assistance, public awareness, and education. The program will support eligible project planning activities and seeks to develop future-looking plans that model and strengthen stewardship, interpretation, and asset management. This program aims to increase recognition of Black architects and their artistic expressions as well as diversify the meaning of American modern architecture and design. The Action Fund invites proposals from a broad pool of applicants who steward these places for public benefit and access.

Grants made from Conserving Black Modernism will total $150,000 each. Funding will be flexible and can support planning activities, limited capital improvements, and indirect costs. Funding ratios will be balanced to support and prioritize comprehensive project planning needs. For example, a $150,000 project planning grant with 10% indirect can be allocated to advance a full-scale building evaluation and preservation plan. The grant period for this type of project will be 12 months.

Conserving Black Modernism grants can also support projects consisting of a mix of project planning and limited capital improvements. Funding ratios will be balanced to prioritize project planning. For example, an applicant may propose a project which allocates $90,000 for planning activities, $45,000 for capital expenses, and $15,000 for indirect expenses. The grant period for this type of project will be 18 months.

Grantees can address the building’s priority needs and experience the full cycle of planning, design, and construction. Additional grantee support will include technical assistance, promotion, and conservation management training.

Historic Asset Example Archetypes

While this is not an exhaustive list, we are particularly interested in the following 20th-century property archetypes:

• Buildings Located on HBCU Campuses
• Community and Cultural Centers
• Schools
• Libraries
• Houses and Residences
• Spaces Associated with Sports & Recreation
• Green Book Sites
• Sites associated with Women’s History
• Sites associated with LGBTQ+ History

Agnes McCarthy Caregiver Foundation

The Agnes McCarthy Caregiver Foundation is a 501(c)(3) not-for-profit charity that provides hope and relief to caregivers who care for a loved one with mental health conditions.

Caregiver Grant

Family caregiving has become a public health issue that receives inadequate recognition in our country. While it can be rewarding to care for our loved ones, it often comes with significant physical, emotional and financial costs to the caregiver. On average, caregivers spend over 25% of their own income to support their loved one and provide 32 hours a week in unpaid care.

AMCF currently offers a $500 financial relief grant to assist family members with unexpected expenses due to their caregiving role. If you are a family caregiver to someone living with a mood or psychiatric condition like depression, anxiety, PTSD, bipolar, schizophrenia, or other mental health/co-occurring conditions, you are not alone, and we welcome you to apply for a caregiver grant today.

Additional Information

• To ensure our limited funds reach families with the greatest need, grants may require documentation confirming a diagnosed serious mental illness (SMI).  

• The $500 grant is limited to one award per household within a 12-month period.

• Applications are generally reviewed by our Board of Directors, with decisions made within 30 days of receipt.

Angel Post Deployment Test Program

Through a collaborative partnership with UNCF, XYZ Corporation has established a scholarship program to help STEM students get on the fast track to a rewarding career. In addition to direct financial support, Intel-sponsored scholarships offer the benefits of exposure to potential job opportunities, networking with fellow scholars, insight to other Intel scholarships, research, training opportunities, and access to Intel mentors offering support on technical, non-technical, cultural, and dissertation-related needs.

The NINDS Alzheimer’s Disease-Related Dementias (ADRD) K99/R00 program promotes diversity by supporting new independent investigators from underrepresented backgrounds in AD/ADRD research. This award facilitates a transition from mentored postdoctoral positions to independent faculty roles, providing essential NIH research support. Applicants must propose research that does not involve leading a clinical trial but may include participation in trials led by mentors. Key deadlines for applications span from October 2024 to June 2027.

The NTSS Toshio Narahashi Neurotoxicology SS Trainee Conference Endowment Award offers a stipend of at least $250 to support deserving trainees in Neurotoxicology attending the SOT Annual Meeting. Selection is based on scientific merit and mentor support. This initiative, funded by the Toshio Narahashi Neurotoxicology Fellowship Award Fund, aims to enhance the professional development of trainees in toxicology.

The Marlene and Spencer Hays Foundation Grants support tax-exempt organizations working to enhance lives through arts, healthcare, education, and youth programs. The foundation requires a Letter of Intent (LOI) from all applicants, emphasizing its mission to select grant recipients who align with its values. Grants are not available for political purposes, endowment campaigns, or organizations that discriminate based on race, gender, or religion. This framework ensures a focused impact on community betterment.

The Remsberg-Trout Scholarship Fund supports local students pursuing STEM degrees. One scholarship assists a senior from Williamsport High School, while two additional scholarships are available for graduates from other Washington County public high schools. All applicants must be members of the National Honor Society. This initiative, part of the Community Foundation of Washington County, MD, aims to foster educational opportunities and enhance the community's future.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a graduating senior who has demonstrated the qualities of honesty, care, trustworthiness, and personal integrity, and who is active in sports and shows an interest in working with children or the elderly.

The FY 2026 funding opportunity aims to support Indian Tribes and intertribal consortia in implementing approved Nonpoint Source management programs under the Clean Water Act Section 319. This initiative, funded by the EPA, focuses on addressing NPS pollution through best management practices as outlined in Tribal NPS Management Program Plans, ensuring the protection of water resources and promoting sustainability in Tribal lands.

The Native American Research Centers for Health (NARCH) program supports federally-recognized American Indian and Alaska Native Tribes and organizations in advancing health-related research. It aims to enhance research careers and infrastructure through a competitive application process. Funded by the US Dept. of Health & Human Services, this initiative invites eligible entities to apply, ensuring that only high-quality proposals undergo peer review for potential funding.

The Excellence in Environmental Engineering and Science Education (E4) Award recognizes outstanding contributions by university faculty in environmental engineering education. Administered by AAEES and AEESP, this annual award includes a $1,000 monetary prize and $500 for travel to the E3 ceremony. Nominees should demonstrate significant impacts in curriculum development, student mentorship, and educational outcomes. Past nominations can be reconsidered for three years, encouraging ongoing recognition of excellence in environmental engineering education.

The ASTRO-AstraZeneca SCLC Therapy Challenge RFP aims to enhance research on limited-stage small cell lung cancer (LS-SCLC) through innovative combination therapies, particularly integrating immunotherapy with advanced radiation techniques. Proposals are encouraged to explore various aspects, including care patterns, treatment workflows, prognostic biomarkers, and toxicity management. The target budget for projects ranges from $175,000 to $375,000, with consideration given to higher requests based on scientific merit, fostering significant advancements in radiation oncology.

The Ryan Myers Memorial Scholarship Fund, established by the Community Foundation of Washington County, MD, supports graduating seniors from various educational backgrounds in Washington County. This scholarship honors Ryan Myers' legacy, encouraging students pursuing higher education, trade schools, or apprenticeships. Ideal candidates reflect Ryan's positive spirit and aspirations, aiming to make a meaningful impact in their communities while achieving their academic and career goals.

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a Notice of Funding Opportunity (NOFO) under the NIH HEAL initiative to enhance research on joint health and pain. This initiative aims to refine the understanding of joint tissues and pain mechanisms, expand clinical phenotyping, and support preclinical testing of novel therapies. Collaborations among experts in neurobiology, pain science, and rheumatic diseases are encouraged to foster innovative solutions for joint pain management.

The Lam Research Core Values Scholarship, offered by the East Bay Community Foundation, supports high school seniors from specific districts in California and Oregon. Recipients are awarded $10,000 over four years, promoting educational success. Eligible students must exemplify Lam's Core Values, maintain a GPA of 2.7 or higher, and plan to attend a college or technical school. This scholarship aims to empower diverse youth in their educational pursuits and foster community development.

Beckley Area Foundation

Beckley Area Foundation was established in January 1985 by ten community-minded citizens. It began with a gift of $1.1 million from the Dr. Thomas Walker Memorial Health Foundation as “seed” money for this Raleigh County project. BAF assets have grown to over $70 million with over 500 different funds managed by our three trustee banks. Today, Beckley Area Foundation is one of West Virginia’s largest community foundations.

Since its inception, BAF has distributed over $23 million to charities and other worthy projects in the fields of education, public recreation, health & human services, the arts, animal services and beautification.

Scholarships

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

Most of these scholarships must be awarded to students from our geographic area or at least preference given to such students. While the majority of scholarships benefit Raleigh County applicants there are others designated for Fayette, Summers, Webster, and Wyoming students. 

The File Girls Cystic Fibrosis Scholarship

Weighted for educational merit, personal achievement and financial need; West Virginia high school matriculating senior with a confirmed diagnosis of Cystic Fibrosis. Recipient will provide physician’s letter affirming a diagnosis of Cystic Fibrosis as part of the application process; The scholarship is to be awarded for post-secondary education through college, vocational or technical schools.

This scholarship is renewable.

TryMarine Grant

The Reservoir Fish Habitat Partnership (RFHP) is seeking candidate pilot sites for evaluating two water quality treatment technologies—TryMarine and Oase Water Technology—in small urban fishing lakes (1–3 acres).

Urban fishing lakes are important community resources, providing accessible angling opportunities and supporting local outdoor recreation. Many of these lakes experience nutrient‑driven water quality impairments such as algal blooms, low dissolved oxygen, and reduced water clarity. These issues degrade fish habitat and diminish angler satisfaction.

This pilot initiative aims to identify lakes where these technologies can be tested to determine their effectiveness, feasibility, and potential for broader application across the RFHP network.

Objectives

Water Quality & Habitat Objectives

• Reduce nutrient concentrations (total phosphorus, total nitrogen).
• Improve water clarity and reduce turbidity.
• Reduce harmful algal blooms (HABs).
• Increase dissolved oxygen stability to support sportfish populations.
• Improve habitat conditions for stocked and naturally occurring fish species.
• Reduce internal nutrient loading from sediments.

RFHP Program Objectives

• Demonstrate scalable tools for improving fish habitat in small urban lakes.
• Support community‑based fisheries enhancement.
• Provide case studies and data for future RFHP guidance.
• Strengthen partnerships among agencies, municipalities, NGOs, and angling groups.

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 300 funds and approximately $80 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Lake County Fish & Game Scholarship

Use the chart below to see which scholarships are the best fit for you! You must complete the Legacy Universal Application to apply.

Scholarship eligibility requires students to attend an accredited 2 or 4 year public or private institution of higher learning. All scholarships are for full-time students, unless otherwise noted. Renewable awards are for 4 years of undergraduate study and cannot be used for post graduate coursework; all awards are paid directly to the school or may be used for book reimbursement.

The monetary value of each scholarship award varies depending upon the amount available in each individual scholarship fund. Scholarship award amounts range from $1,000 - $5,000 for a single year.

Robert and Judy Dreiling Scholarship

This scholarship offered to northern Nevada residents who are high school graduates or who have earned a high school equivalency certificate and adults seeking education to attain better employment.

The ideal candidates will be enrolled in an Associate's Degree track or certificate program at the school of their choice; the degree track or certificate program should result in a good lead to a good job. 

The scholarship will pay up to $5,000 for an Associate’s Degree or certificate program at private trade schools or community colleges for one or more candidates. You will be asked to write brief essays discussing: your life, your plans for the future, why you chose your certificate program, and how your education will impact your life and your family.

The Bicycle Advocacy Grants Program, supported by New Belgium Brewing Co, aims to foster community engagement through bicycle projects. With over $11.3 million donated since its inception in 1995, the program focuses on breaking down barriers to cycling and promoting accessibility for all. Projects targeting increased ridership and addressing systemic inequities are prioritized. This initiative reflects New Belgium's commitment to sustainability and social equity, enhancing community connections through the joy of cycling.