Best Addiction and Substance Abuse Grants in Maine

Maine addiction and substance use researchers can access funding through the National Institutes of Health to study screening, brief intervention, and referral to treatment or prevention (SBIRT/P) for alcohol, tobacco, and other drug use in adults facing health disparities. Projects must prospectively test SBIRT/P approaches and collaborate with healthcare and community partners; multiple application cycles run through 2027.

Grants from the National Institutes of Health help U.S. research institutions test screening, brief intervention, and referral to treatment or prevention (SBIRT/P) approaches for alcohol, tobacco, and other drug use in adults experiencing health disparities. Maine addiction and substance use researchers collaborating with healthcare or community partners may be eligible to conduct prospective clinical trials under this R01 opportunity.

Nonprofit 501(c)(3) organizations in Maine working to improve economic opportunity, education, health, or community well-being for underserved communities can access multi-year general operating support through the River Rock Shared Future Fund. Focused on racial equity, this Maine Community Foundation program can support addiction and substance use disorder initiatives that address health disparities and community healing.

Nonprofit and local government organizations offering addiction and substance use disorder services, education, health, housing, arts, or related programs can apply for funding, including those in Maine serving Native American communities. Focused on charitable purposes, the Confederated Tribes of Siletz Indians invites Native American organizations across the U.S. to support prevention, treatment, and community well-being.

Nonprofits and local governments in Maine can access funding for operating costs, equipment, and program materials that serve low- and moderate-income people through the CDBG Public Service Grant Program. Maine Department of Economic and Community Development supports addiction and substance use disorder services, including counseling and treatment, alongside related health, housing, and community programs; awards up to US $50,000.

The Rural Communities Opioid Response Program focuses on enhancing behavioral health care services for children and adolescents in rural areas. By providing essential funding, this initiative aims to tackle mental health and substance use disorders, ensuring that young individuals receive the support they need. The program, administered by the Health Resources and Services Administration, is crucial in addressing the unique challenges faced by rural communities, promoting healthier outcomes for future generations.

Just One More Grant aims to transform lives by providing financial support to individuals and nonprofit organizations in the U.S. who are overcoming challenges like mental health issues, drug misuse, and educational barriers. The foundation encourages applications from those committed to personal growth and community support. Though current grants are paused for nonprofits, interested individuals with actionable plans are invited to apply. More information and past winners can be found on their website.

This funding opportunity invites Small Business Technology Transfer (STTR) grant applications aimed at developing FDA-regulated medical products for patients with opioid and stimulant use disorders. Projects may focus on pharmacotherapeutics or diagnostic devices, including software. The initiative seeks to address the ongoing opioid crisis by supporting innovations that enhance treatment options for individuals and communities affected by these disorders.

The HEAL initiative aims to translate addiction research into practice to combat the opioid crisis and overdose events. It focuses on identifying barriers to reducing substance use and developing scalable, evidence-based interventions. Emphasizing recovery, prevention, and the integration of mental health, the initiative encourages collaboration among experts in various fields. Although applications are not currently solicited, potential applicants are urged to prepare for future opportunities to apply innovative solutions to enhance addiction treatment and prevention efforts.

The Opioid Crisis Response Program Fellowship, offered by Equal Justice Works, addresses the opioid epidemic by mobilizing public interest lawyers to provide vital civil legal aid to underserved communities affected by Opioid Use Disorder. This two-year fellowship enables attorney fellows to advocate for clients' rights, reduce barriers to treatment, and enhance community education about legal impacts. Through collaboration with various stakeholders, the program aims to improve health outcomes and foster systemic change in the fight against this public health crisis.

Organizations providing research education experiences in substance use and addiction can apply for NIH funding of up to US $1,250,000, open to applicants in Maine and other eligible U.S. jurisdictions. Focused on skills-development courses and hands-on research experiences, the National Institutes of Health invites programs that broaden and diversify the addiction science workforce.

Institutions supporting clinician scientists in addiction and substance use disorder research can seek up to US $750,000 to run mentored career development (K12) programs, including in Maine. Grants from the National Institutes of Health help build intensive, supervised research training that prepares Scholars for independent substance use and substance use disorder research careers across eligible U.S. locations.

Research institutions and teams conducting HIV and substance use studies can apply for NIH funding of up to US $1,500,000, including work impacting Maine. Focused on high-priority HIV and substance use research, the U.S. Department of Health and Human Services’ National Institutes of Health supports projects from basic science to clinical and implementation research.

The National Cooperative Drug/Device Discovery/Development Groups (NCDDG) program invites applications to foster innovative research in treating mental disorders and substance use issues. This initiative promotes collaboration between academia and industry, supporting diverse, multidisciplinary projects aimed at developing rational therapies and neurostimulation techniques. Applicants are encouraged to submit Letters of Intent 30 days before the proposal deadline to enhance project alignment with funding goals.

The NCDDG program supports innovative research aiming to discover and develop new treatments for mental disorders, including substance use and alcohol use disorders. This initiative encourages collaborations between academic and industry partners to advance neurostimulation techniques and drug/device development. Applicants are invited to submit proposals that focus on specific projects utilizing the U01 mechanism, with a clear emphasis on rationally designed candidate agents and cutting-edge technologies. Letters of Intent are encouraged 30 days prior to the submission deadline.

Doctoral candidates conducting substance use or substance use disorder research in Maine can apply for up to US $100,000 to support completion of their dissertation projects. Grants from the National Institutes of Health help researchers whose work aligns with NIDA priorities, including those who contribute to diversifying the addiction research workforce.

Maine research institutions and clinical organizations working on addiction medicine, anesthesia, and pain management can access funding through the FDA to conduct U.S.-based clinical trials and related studies. Grants support developing, implementing, and evaluating evidence on analgesics, anesthetics, and substance use disorder treatments, with awards around US $2,000,000 for comprehensive, evidence-based research plans.

Maine addiction and substance use researchers can access funding through the National Institutes of Health to study the harmful effects of acute exposure to ultra-potent synthetic opioids and combinations like fentanyl and xylazine. Eligible U.S. and territorial institutions may receive up to US $1,500,000 for basic research on acute and longer-term pathophysiological impacts.

Clinically focused education programs on substance use and substance use disorders in Maine and other U.S. locations can apply for up to US $350,000 to enhance clinician and clinical researcher training. Grants from National Institutes of Health help medical education initiatives deepen knowledge of addiction, drug use disorders, and related behavioral and clinical research.

Research institutions and similar organizations studying tobacco, alcohol, or cannabis policy and health equity can seek up to US $2,500,000 for U.S.-based projects. US Dept. of Health & Human Services: National Institutes of Health (NIH) supports addiction and substance use disorders research that engages community partners and advances cancer prevention and reduced exposure among disproportionately affected populations, including those in Maine.

Researchers and research institutions studying addiction and substance use disorders in Maine and other U.S. jurisdictions can seek up to US $275,000 for time-sensitive pilot or exploratory projects. US Dept. of Health & Human Services: National Institutes of Health supports rapid studies on emerging drug issues, shifting marijuana policies, prescription drug abuse, healthcare system changes, and justice-related drug concerns.

Grants supporting research organizations studying tobacco, alcohol, or cannabis policy and health equity can access funding through the National Institutes of Health in Maine and other U.S. jurisdictions. Awards up to US $275,000 back projects on substance use, secondhand exposure, and cancer prevention that authentically engage community partners and address addiction-related disparities.

The Rural Communities Opioid Response Program - Overdose Response aims to enhance healthcare access in rural areas by addressing urgent needs related to substance use disorder services. This initiative focuses on reducing overdose risks through targeted interventions and support, ensuring that rural communities receive necessary assistance. Funded by the Health Resources and Services Administration, this program is crucial for mitigating the opioid crisis in underserved regions, improving health outcomes, and promoting overall community well-being.

The BJA FY 2026 Second Chance Act Family-Based Substance Use Disorder Treatment Program aims to provide essential treatment and recovery support services for parents with substance use disorders (SUD) who have minor children or are pregnant. Eligible applicants include state, local, tribal governments, and nonprofit organizations, which can apply for funding to implement family-based programs in various settings. This initiative seeks to reduce recidivism and enhance reentry outcomes for both parents and their children.

The BJA FY 2026 Comprehensive Opioid, Stimulant, and Substance Use Site-Based Program aims to combat the rising crisis of substance use and overdose deaths. This funding opportunity supports state, local, territorial, and tribal governments in implementing comprehensive responses, including law enforcement initiatives, prevention programs, and recovery services. Applications are due by October 1, 2026, providing a crucial chance to enhance community safety and health through targeted interventions.

The BJA FY 2026 Public Safety and Mental Health Initiative aims to enhance public safety by addressing untreated mental illness and substance use. This program supports coordinated intervention efforts across various agencies, improving access to treatment and reducing recidivism. By fostering comprehensive service networks, it seeks to restore order in communities affected by homelessness and mental health challenges, ultimately enhancing community well-being and trust in public spaces.