Best Operating Grants for Nonprofits in Maine

Tee It Up for the Troops Grant supports 501(c)3 organizations that aid military personnel and their families. Prioritizing employment, family support, housing, PTSD treatment, sports rehabilitation, and suicide prevention, the grant aims to enhance the lives of veterans. Organizations that do not engage in fundraising events are eligible for funding. This initiative seeks to create a positive impact within the military community through various support pillars.

The AWWA Abel Wolman Fellowship, established in 1984, supports highly qualified students conducting meaningful research in water supply through doctoral programs. Named after Dr. Abel Wolman, this prestigious award recognizes excellence and creativity in the water sector. The fellowship provides up to two years of financial support, with an initial award of $30,000 for the first year, aimed at fostering the next generation of water professionals in the U.S., Canada, and Mexico.

Offshore Wind Science and Research RFP

Massachusetts remains committed to offshore wind as a key energy source to provide critically needed energy, spur economic development, and create good-paying jobs. MassCEC recognizes that offshore wind development occurs in a dynamic ocean environment that supports existing marine industries of economic and cultural importance, is inhabited by critically endangered wildlife, and is itself undergoing climate-induced changes. These variables, among others, present a wide range of technical, logistical, and analytical research opportunities related to the offshore wind industry, particularly now that several projects have or soon will reach commercial operation. Focused science and research activities, and the organizational capacity to conduct that science and research, are needed in the near- and long-term to inform, optimize, and catalyze industry growth.   

The 2026 RFP will fund up to $2.5 million for projects aligned with priority research areas identified by MassCEC. While a broad array of research projects will be eligible to apply, this round of funding has also specified topic areas of interest within each of the following categories:

• Fisheries: Understanding Effects in Southern New England Lease Areas
• Wildlife and Habitat
• Regional Transmission Planning
• Gulf of Maine Regional Monitoring
• Communicating Existing Science and Research

MassCEC has allocated up to $2.5 Million Dollars ($2,500,000) in funding for awards and commitments under the Solicitation. We expect that awards will range from approximately $50,000 to $500,000. An application proposing higher amounts of MassCEC funding must present a compelling case for the funding need and potential outcomes toward achieving the Objectives.

Tree Research and Education Endowment Fund (TREE Fund)

TREE Fund is a 501(c)3 nonprofit whose mission is to support scientific discovery and dissemination of new knowledge and best practices in the fields of arboriculture and urban forestry.

TREE Fund’s research and education programs shape industry best practices, improve workforce safety and contribute to the long-term sustainability of our communities in the following crucial ways:

• Improving the quality of nursery grown trees and overall tree survival through the development of hardier, drought- and disease-resistant species.
• Stopping diseases and pests while reducing pesticide use with the evolution of integrated pest management programs.
• Enhancing public and workforce safety with advanced tree risk assessment techniques and greater knowledge about why and how trees fail.
• Quantifying the benefits of trees which makes it easier for governments and businesses to project their return on tree care investment.
• Revolutionizing global best practices for growing strong, healthy landscape trees.
• Connecting youth with nature to promote environmental stewardship in the next generation and inspire them to consider careers in green industries.

Lucas Tree Experts Integrated Vegetation Management Endowed Research Fund

Since 1926, John Lucas Tree Expert Co. has worked with investor-owned utilities, electric cooperatives, municipalities, railroads, and pipeline customers throughout the United States and Canada. Innovation has always been a core value, and Lucas remains committed to innovation that makes the industry safer, greener, and more efficient. The Lucas Tree Experts Integrated Vegetation Management Endowed Research Fund is a new endowment fund of Tree Research and Education Endowment (TREE) Fund created to support research in Integrated Vegetation Management in the United States and Canada.

This fund program was created in 2026 to help celebrate Lucas Tree’s 100th anniversary. Lucas Tree’s anniversary marks a century of innovation, safety, and stewardship in utility vegetation management.

Projects are expected to be completed within one to three years. No project may receive more than one award from this program.

Application Requirements can be found here.

The AWWA Arcadis Scholarship offers a $5,000 award to graduate-level students from underrepresented racial and ethnic minority groups pursuing STEM fields. This initiative by the American Water Works Association aims to promote diversity and inclusion in the water service industry, recognizing the critical role of future leaders in ensuring sustainable water supply. Eligible candidates include Black, Latinx, and American Indian or Alaska Native students with the potential for impactful contributions in the sector.

The Carl & Marilynn Thoma Foundation offers Collections-Related Grants for Nonprofits, aimed at enhancing public interest in art through innovative projects. Grants support exhibitions, academic convenings, research, and catalog publication, focusing on art from the Spanish Americas, digital media, and more. The foundation prioritizes proposals from 501(c)(3) organizations in the U.S., particularly from New Mexico, Oklahoma, and Texas, fostering partnerships that advance art scholarship and cultural engagement.

The NIDDK High Risk Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34) aims to support high-risk, multi-center clinical studies by facilitating early peer review and assessment of study designs. This program helps in the development of necessary operational documents and essential elements for conducting hypothesis-driven studies focused on diseases relevant to NIDDK. Applications are due by 5:00 PM local time, and consulting with NIDDK staff is strongly encouraged.

The Chemical Countermeasures Research Program (CCRP) Initiative aims to support vital research on the harmful effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids, including fentanyl and its combinations. This funding opportunity encourages studies that enhance understanding and mitigation strategies for these substances, focusing on both immediate and long-term health impacts. Applications are due by 5:00 PM local time, with optional Letters of Intent accepted 30 days prior to the proposal deadline.

The Michael & Susan Dell Foundation provides grants to organizations focused on improving the lives of children in urban poverty in the U.S., India, and South Africa. They prioritize projects in education, health, and family economic stability. Grants typically do not exceed 25% of a project's budget or 10% of an organization's annual expenses. The foundation seeks to partner with organizations already making an impact, ensuring funding supports impactful social enterprises.

The Ethel Strickarz Memorial Scholarship aims to address community needs through educational support in special education and related fields. Funded by the Community Foundation of Elmira-Corning and the Finger Lakes, it encourages students pursuing careers in human services, nursing, psychology, speech pathology, or therapy. This scholarship reflects a commitment to holistic community development by fostering future professionals dedicated to improving lives and addressing urgent societal challenges.

The Educational Incentive Award Application by the Cooley’s Anemia Foundation aims to support children of individuals with severe thalassemia in pursuing their educational and career aspirations. With a total funding of $10,000 for the 2025-2026 school year, awards range from $500 for two-year programs to $1,000 for higher degree studies. Eligible applicants must be diagnosed with specific thalassemia types and provide necessary documentation, including a 250-word essay detailing their educational goals.

The Nicholas B. Ottaway Foundation offers grants through its Education Committee to support programs enhancing educational opportunities for economically disadvantaged students. These grants focus on initiatives like tutoring, college preparation, and internship programs. To qualify, organizations must be tax-exempt under 501(c)(3). Preference is given to projects that provide ongoing support to students post-graduation, particularly in specific geographic areas such as San Diego County and the New York Metropolitan Area.

St. Mary's Bank Charitable Foundation Community Support Grants aim to enhance community welfare by providing financial support to nonprofit organizations. With a commitment to 'people helping people' since 1908, the foundation focuses on areas like youth programming, homelessness, and civic support. In 2023 alone, they donated over $200,000 to 190 organizations, reflecting their dedication to improving lives in New Hampshire. They prioritize funding for nonprofits within their service areas, ensuring impactful contributions to local communities.

Joseph G Markoly Foundation Inc

When Joseph Markoly originally established the foundation more than thirty years ago, its focus was on Alzheimer’s and heart disease support, funded through a number of the larger national disease-related organizations. Over time the focus has shifted to helping small to mid-size organizations in our local communities which support children and seniors in a variety of effective ways. 

Markoly Foundation was established in honor of Joseph G. Markoly, an entrepreneur and philanthropist who wanted to make a positive impact in people’s lives. Joseph’s family was affected directly by both Alzheimer’s and heart disease having lost a family member to each condition. For that reason, the foundation dedicates a majority of their resources to providing grants to organizations that focus on the treatment of each of these diseases. In addition, Markoly Foundation supports a variety of programs dedicated to helping children and seniors by providing services, supplies, programs and research in areas impacting these demographics.

Joseph G. Markoly Foundation Grant Support for Elder Organizations

The Markoly Foundation takes pride in supporting local organizations that provide services for elders in our community. Seniors face a number of challenges that come with aging, especially when they don’t have loved ones who are able to assist them with their needs. We provide grants for a variety of senior-related programs from Caregiver Education and Support to Emergency Meal Delivery and Transportation Services.

We are dedicated to providing funding for local nonprofit programs that improve the quality of life for all, but particularly for the children and elders in our community.

The RMEF Grant Program lies at the core of advancing our mission.

RMEF established the program in 1986 to provide financial and logistical support to projects that align with our priorities and goals. Grant funds raised by RMEF members, volunteers and generous donors from across the country translate into significantly more conservation accomplishment when matched with partner funds. The RMEF Grant Program also aims to build recognition for RMEF’s work, grow engagement, and boost local fundraising efforts.

Governed by clear guidelines and criteria, the RMEF Grant Program seeks to foster meaningful collaborations and long-term impacts in the conservation of natural resources and outdoor traditions. Grant project partners include federal, state, local, and tribal wildlife and land management agencies, private landowners and local stakeholders, sportsmen and women, and conservation organizations, universities, foundations and the outdoor industry. Eligible projects primarily focus on habitat stewardship, land conservation and access, wildlife management, and hunting heritage.

We support organizations recognized by the Internal Revenue Service (IRS) as a 501(c)3 entity, federal, state, local, or tribal government entities, sportsmen’s organizations, or educational institutions. All applicants must have a Federal Employer Identification Number (EIN) issued by the IRS. RMEF does not offer grants to individuals.

Hunting Heritage

Ensuring our hunting heritage is central to RMEF’s mission. Hunters—America’s first conservationists—remain the driving force behind wildlife conservation. RMEF funds hunting heritage and conservation education to help more people experience the outdoors, learn the skills of hunting, and carry forward the traditions that define big game country, including outdoor skills programs/events, hunter or conservation outreach, mentored hunts, and other similar activities.

The Thalassemia Patient Incentive Award, sponsored by the Cooley’s Anemia Foundation, aims to support thalassemia patients in pursuing their educational and career aspirations. Awards ranging from $250 to $2,000 will be granted to students at various academic levels, with applications due in March 2026. This initiative not only encourages academic growth but also fosters a positive outlook among patients living with thalassemia, underscoring the Foundation's commitment to improving their quality of life.

Funding Innovative Research

Cannonball Kids’ cancer Foundation (CKc) prioritizes funding clinical trials, research that is nearing translation to a clinical trial, and young investigator grants.

Grants funded by CKc must be innovative and provide better quality of life or symptom relief than current treatments. 

When possible, CKc will prioritize funding research:

• with a focus on cancers that are under-funded or under-researched,
• with a focus on patient populations who are traditionally underserved.

When possible, CKc will prioritize funding researchers of diverse backgrounds.

For CKc, “innovation” means the invention or application of novel methods or treatments, specifically treatments that have fewer side-effects than standard care, increase a child’s quality of life, and/or create an option for care where there otherwise were few or none (either on primary diagnosis, relapse, or for recalcitrant cancers).

Research Grants

Grant Program: Clinical Trial

$200,000 over 3 years

• PI must hold an academic appointment at the Assistant Professor level or higher
• Preclinical studies must be complete
• If an FDA Investigational New Drug (IND) application is necessary for the proposed clinical study, the IND application should already have passed FDA initial review and be active
• If the PI has recruited additional patient enrollment sites, local IRB approval must be obtained for each site.

• How many treatment options would this study provide for children?
• How accessible is this study for children and families to access?

Headstream Accelerator 2026

Accelerator Application Cohort VI

The Headstream Accelerator supports entrepreneurs from all backgrounds in scaling digital solutions that improve the mental well-being of teens at risk, with a focus on the education and healthcare sectors. Our four-month, virtual-first program is designed for early-stage innovators, helping them strengthen their business models, refine their value propositions, and build the foundation for sustainable growth and meaningful impact.

Benefits:

• $30,000 non-dilutive stipend 
• Partnership with youth from Headsteam’s Youth Co-Creator Club to gain insights on cultural relevance, age-appropriateness, and user experience, ensuring your solutions resonate deeply and effectively with the next generation 
• Access to a network of expert advisors, connect with a community of founders, and engage with potential investors and capital providers 
• Access to one-on-one and group coaching sessions with our partner, FounderWell

Participant Expectations:

• Attend all activities, including virtual cohort and youth co-creation sessions, advisor calls, and an in-person kickoff event from July 28–30, 2026
• Commit 2–5 hours weekly during the program, including virtual sessions, advisor network office hours, guide calls, and more
• Embed youth voices throughout your product development

The AAAP Foundation: Poultry Scholarship supports students pursuing careers in poultry health and food safety in North America. Offered by the American Association of Avian Pathologists, the scholarship aims to enhance scientific knowledge and promote the well-being of poultry. Eligible candidates must be enrolled in accredited veterinary colleges or universities with relevant programs. Scholarships may reach up to $1,500, with undergraduate awards capped at $500, fostering the next generation of poultry medicine professionals.

The 2026 National Urban and Community Forestry Challenge Cost Share Grant Program aims to tackle economic, health, and environmental issues in communities through innovative tree resource utilization. By transforming wood from various sources into valuable products like lumber and biochar, this initiative promotes local economies and enhances community resilience. Projects should align with community forestry plans, adhere to safety standards, and provide job creation opportunities, ultimately fostering sustainable urban forest management and utilization.

The Harris and Frances Block Foundation, established in 2001, supports small grassroots organizations focused on social and environmental justice. They prioritize equitable solutions and sustainable community development, funding initiatives related to environmental education, justice, and food security. Grants are available to non-profit, tax-exempt organizations in specific geographical areas including Vermont, North Carolina, Virginia, and New York City, excluding funding for lobbying, land acquisition, and scholarships.

Harry C. Anthony, Jr. Scholarship

Essay:

• Describe yourself and explain why you are interested in a career in medicine.

Awards:

• One-time award of $2,500

The OVC FY 2026 Housing Assistance for Victims of Human Trafficking program aims to provide vital housing and support services for victims of human trafficking. This initiative, led by the U.S. Department of Justice, focuses on rapid rehousing, ensuring victims transition quickly into stable, permanent housing. Organizations interested in applying must demonstrate their capacity to deliver comprehensive support aligned with federal guidelines. Applications are due by October 5, 2026, through JustGrants.

Sun Life’s Health Access Grant Program aims to enhance access to health services, specifically targeting diabetes and oral health in local communities. With funding options ranging from $25,000 to $100,000, this program supports 501(c)(3) charities focused on diabetes prevention, management, and oral health care. By fostering access to essential health services, Sun Life is committed to building healthier communities and addressing health disparities faced by underprivileged populations.

The Gamma Mu Foundation, established in 1988, aims to support the LGBT community in rural and underserved areas through various grants. Initially focused on HIV/AIDS projects, it now funds scholarships and services for diverse LGBT subpopulations. With over $2 million awarded, the Foundation prioritizes initiatives that enhance community support, public education, and health programs. It emphasizes projects that build organizational capacity and provide essential services where resources are limited, ensuring ongoing support for vital health and social services.

The NALMS Achievement Awards: Secchi Disk Award recognizes outstanding contributions to lake management by its members. NALMS aims to unite citizens, scientists, and professionals to ensure the protection and management of lakes and reservoirs. This prestigious award is open to NALMS members, with nominations encouraged from any individual or entity. However, current board and committee members are ineligible. The award celebrates those who significantly advance NALMS's goals and objectives in fostering lake ecosystem awareness and management.

The Jim Flynn Outstanding Corporation Award, presented annually by NALMS, honors the corporation that has made significant contributions to advancing lake management goals. This award emphasizes the importance of facilitating information exchange, promoting public awareness of lake ecosystems, and supporting management programs at all levels. Eligible nominations can come from any individual or entity, focusing on achievements in lake and reservoir management. Notably, current NALMS board members and awards committee members are excluded from eligibility.