Best Marion County Grants for Nonprofits in Indiana

The Hagerstown Garden Club Scholarship, administered by the Community Foundation of Washington County, supports Washington County residents pursuing education in horticulture. Eligible applicants include graduating high school seniors and current college students with a minimum GPA of 3.0. This scholarship honors the legacy of the Hagerstown Garden Club and is part of a broader initiative to enhance community life through educational opportunities, fostering both personal and professional growth in the horticultural field.

Indiana Department of Health

The Indiana State Department of Health became the Indiana Department of Health (IDOH) in July 2021 after the Governor signed legislation updating the agency's statute. That same year the Department was also awarded accreditation by the Public Health Accreditation Board, joining the ranks of 36 other states and territories.

Mission: To promote, protect, and improve the health and safety of all Hoosiers.

Tactical Urbanism Demonstration Projects Supporting Active Transportation

The Indiana Department of Health (IDOH) is providing funding for Indiana communities to assist in the design and implementation of low-cost pop-up, tactical urbanism demonstration projects that support active living in Indiana. This funding will assist grantees in the planning, preparation, and implementation of one or more tactical urbanism demonstration projects in their communities. Eligible applicants include cities, towns, counties, regional planning agencies (such as MPOs), school corporations, and not-for-profit groups. This grant is managed by the Division of Nutrition and Physical Activity.

INDOT Mission

Together, we plan, deliver, and maintain a safe, efficient, and innovative transportation system that:

• Enhances the daily lives of Hoosiers.
• Strengthens Indiana’s economy
• Embraces evolving transportation needs.

Rural Transit Programs

Purpose

The Federal Section 5311 Program was created to provide public transportation in non-urbanized areas (population of 50,000 or less). The purpose of the program is to provide transportation to people living in rural areas. The Federal Section 5311 Program supports rural public transportation through operating, capital, and intercity transit funding.

Operating Project Grants

Operating Grants provide assistance for the operations of the transit service. Section 5311 may fund up to 50 percent of the net operating costs.

INDOT will make Section 5311 funds available for operating expenses, which generally include salaries and wages, fringe benefits, purchase of transit service contracts, fuel, oil, lubricants, replacement parts, tires, vehicle insurance, licenses, and other expenses.

INDOT Mission

Together, we plan, deliver, and maintain a safe, efficient, and innovative transportation system that:

• Enhances the daily lives of Hoosiers.
• Strengthens Indiana’s economy
• Embraces evolving transportation needs.

Rural Transit Programs

Purpose

The Federal Section 5311 Program was created to provide public transportation in non-urbanized areas (population of 50,000 or less). The purpose of the program is to provide transportation to people living in rural areas. The Federal Section 5311 Program supports rural public transportation through operating, capital, and intercity transit funding.

Capital Project Grants

Capital projects generally include expenses for purchasing vehicles, communication equipment, fare boxes, passenger shelters, and construction of and rehabilitation of transit facilities. Section 5311 capital assistance may fund up to 80 percent of the total capital costs.

INDOT Mission

Together, we plan, deliver, and maintain a safe, efficient, and innovative transportation system that:

• Enhances the daily lives of Hoosiers.
• Strengthens Indiana’s economy
• Embraces evolving transportation needs.

Rural Transit Programs

Purpose

The Federal Section 5311 Program was created to provide public transportation in non-urbanized areas (population of 50,000 or less). The purpose of the program is to provide transportation to people living in rural areas. The Federal Section 5311 Program supports rural public transportation through operating, capital, and intercity transit funding.

Intercity Projects

Section 5311(f) also funds capital, operating, planning and marketing projects for intercity transportation projects. An intercity project is defined as public transit service with limited stops over fixed routes connecting two or more urban areas. Projects may also include the transportation of residents of non-urbanized areas to and from urbanized areas.

Intercity capital projects funded under Section 5311(f) are also funded at the eighty percent level.

Indiana Criminal Justice Institute

The Indiana Criminal Justice Institute (ICJI) is the state planning agency for criminal justice, juvenile justice, traffic safety and victim services. The institute develops long-range strategies for the effective administration of Indiana's criminal and juvenile justice systems and administers state and federal funds to carry out these strategies.

Through the use of evidence-based decision-making, ICJI works to improve the efficiency of the criminal justice system, from calls for service through post-conviction. The agency accomplishes this by bringing together key leaders from the criminal justice system at the state, local, and national levels to identify critical issues facing Indiana. The agency evaluates policies, programs, and legislation designed to address these issues. ICJI is designated as the State Administering Agency for distribution of federal funds, and as the State Statistical Analysis Center for research.

Sexual Assault Victim Assistance Fund Grant

Funded by the Indiana General Assembly, the Sexual Assault Victim Assistance Fund (SAVAF) program aims to provide a comprehensive statewide response for victims of sexual assault.

The Sexual Assault Victim Assistance Fund (SAVAF) was created to:

• Establish and maintain Rape Crisis Centers (RCC);
• Enhance services provided by existing Rape Crisis Centers; and
• Develop, implement, and expand trauma-informed sexual assault services.

SAVAF is a reimbursement-based grant.

About the Indiana State Department of Agriculture

The Indiana State Department of Agriculture (ISDA) was established as a state agency by the Legislature in 2005. ISDA reports to the Lt. Governor, who also serves as Indiana’s Secretary of Agriculture and Rural Development. Major responsibilities include advocacy for Indiana agriculture at the local, state and federal level, managing soil conservation programs, promoting economic development and agricultural innovation, serving as a regulatory ombudsman for agricultural businesses, and licensing grain firms throughout the state.

Resilient Food Systems Infrastructure (RFSI) Grant Program

The Indiana State Department of Agriculture (“ISDA”), Division of Economic Development is seeking applications for the Indiana Resilient Food Systems Infrastructure Grant Program (RFSI) to carry out projects that enhance the resilience of middle-of-the-food-supply-chain.  Applicants/Grantees applying for infrastructure program funding are permitted to claim indirect costs under the RFSI Program, not to exceed the 10% de minimis cap. Applicants/Grantees applying for special equipment-only funding are not eligible to claim indirect costs. ISDA encourages applications from woman or veteran owned businesses, socially disadvantaged businesses and historically underserved farmers, ranchers, and underserved communities.

Grant funding may not be used on meat, poultry, wild caught seafood, food for animal consumption or dietary supplements. If these items are included in your project, your project must clearly define what percentage of your project will include these items and you must be able to demonstrate that no grant or matching funds are used for those portions of the project.

Projects must choose ONE of two project options: Option 1- Special Equipment Only; Option 2- Infrastructure Projects. You may not do both project options.

Option 1- Special Equipment Only

For this project pathway, grant funding requests must be between $10,000 and $100,000. The only eligible expense in the budget for this project is the special equipment to be purchased. The equipment does not have to be American made and can be a used piece of equipment as long as the equipment is in good, working order. You may not include training for the piece of equipment in the budget. You may include installation of equipment if it is included in the quote and does not require construction of the space the equipment will be placed in. Matching funds are not required for Special Equipment Only projects. 

The WaterSMART Cooperative Watershed Management Program offers funding to eligible entities for developing local solutions to water management issues. This initiative supports watershed group development, restoration planning, and project design, promoting stakeholder cooperation and improving water reliability. It aligns with key priorities from the Trump administration, addressing complex water challenges and enhancing federal grant oversight. By facilitating these efforts, the program aims to stretch limited water resources and foster collaborative solutions among diverse stakeholders.

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is inviting applications for the Clinical Trial Cooperative Agreement Program. This funding opportunity supports investigator-initiated, interventional clinical trials at various phases. Initial funding will facilitate the preparation needed to start trials, with successful milestones leading to further support. NIAMS emphasizes hypothesis-driven trials that promise significant clinical impact within its research mission.

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a funding opportunity for Exploratory Clinical Trials Grants. This program aims to support innovative clinical trials that enhance the understanding and treatment of arthritis and other musculoskeletal and skin conditions. Research proposals should focus on early-stage trials, including first-in-human studies, dose-finding, and biomarker evaluation. The initiative encourages the translation of promising laboratory findings into effective clinical practices, ultimately improving patient outcomes.

About the Indiana State Department of Agriculture

The Indiana State Department of Agriculture (ISDA) was established as a state agency by the Legislature in 2005. ISDA reports to the Lt. Governor, who also serves as Indiana’s Secretary of Agriculture and Rural Development. Major responsibilities include advocacy for Indiana agriculture at the local, state and federal level, managing soil conservation programs, promoting economic development and agricultural innovation, serving as a regulatory ombudsman for agricultural businesses, and licensing grain firms throughout the state.

Resilient Food Systems Infrastructure (RFSI) Grant Program

The Indiana State Department of Agriculture (“ISDA”), Division of Economic Development is seeking applications for the Indiana Resilient Food Systems Infrastructure Grant Program (RFSI) to carry out projects that enhance the resilience of middle-of-the-food-supply-chain.  Applicants/Grantees applying for infrastructure program funding are permitted to claim indirect costs under the RFSI Program, not to exceed the 10% de minimis cap. Applicants/Grantees applying for special equipment-only funding are not eligible to claim indirect costs. ISDA encourages applications from woman or veteran owned businesses, socially disadvantaged businesses and historically underserved farmers, ranchers, and underserved communities.

Grant funding may not be used on meat, poultry, wild caught seafood, food for animal consumption or dietary supplements. If these items are included in your project, your project must clearly define what percentage of your project will include these items and you must be able to demonstrate that no grant or matching funds are used for those portions of the project.

Projects must choose ONE of two project options: Option 1- Special Equipment Only; Option 2- Infrastructure Projects. You may not do both project options.

Option 2- Infrastructure Projects

For this project pathway, grant funding requests must be between $100,000 and $3 million. Matching funds of 50% of the total project cost are required unless the applicant qualifies as a Historically Underserved Farmer or Rancher by the USDA standards or a Socially Disadvantaged Business, Women Owned or Veteran Owned business by SBA standards (See Section A for definitions), then you qualify for a 25% match of the total project cost. Infrastructure projects may include, but are not limited to: construction, transportation, equipment, training, renovation, or expansion. Please contact ISDA if you have questions regarding eligibility of your infrastructure project.

Mission

The Indiana Office of Community and Rural Affairs works with local, state and national partners to provide resources and technical assistance to aid communities in shaping and achieving their vision for community and economic development.

Recovery Housing Program

Program Description

The Recovery Housing Program (RHP), authorized by the SUPPORT for Patients and Communities Act (SUPPORT Act), assists local government units and their eligible nonprofit partners (if applicable) in providing individuals recovering from substance use disorders with temporary transitional housing (up to two years) as they work toward sober, independent living. Competitive projects must

demonstrate the following:

• The project must directly advance the objectives of the SUPPORT Act.
• The project must fulfill the national objectives outlined in the Housing and Community Development Act of 1974, as amended and modified by FR-6225-N-01.
• The project supports the community’s long-term planning and development goals.
• The funds granted will significantly advance the project’s success.
• The community has demonstrated clear evidence of strong local support and a commitment to the project’s long-term sustainability.
• The project must be prepared to commence upon receipt of the grant.

Indiana DWD – Who We Are

The Indiana Department of Workforce Development (DWD) strengthens Indiana by understanding workforce needs, aligning resources, and providing access to services that empower Hoosiers to thrive in an ever-changing economy. By helping to ensure economic security and better employment outcomes for all Indiana residents, the state government agency prides itself on acting with integrity, accountability, and respectfulness while continuously striving to support employers, as well as guide and upskill job seekers.

Education & Advanced Manufacturing/Logistics Apprenticeship Grant Opportunity (Round 1)

The purpose of this RFA is to solicit applications from qualified non-profit organizations to facilitate the expansion of Registered Apprenticeship Programs (RAPs) and Certified Pre-Apprenticeship in both number of available programs and individual participants in the occupations of Education as well as Advanced Manufacturing and Logistics. The outcome of this expansion will focus on the number of programs created, number of participants assisted, as well as the development of communities of practice through award recipients. 

Funds not distributed in the first round will be available in subsequent rounds of grant opportunities.

Family and Social Services Administration of Indiana

We are steadfast in our mission to break the cycle of poverty by providing Hoosiers with the healthcare, social services, and support necessary to achieve lasting economic independence. Through thoughtfully designed and fiscally sustainable programs, we equip individuals and families with the resources and opportunities they need to build stability, reclaim dignity, and secure long-term success.

School Age Child Care Grant

The Office of Early Childhood and Out of School Learning will support licensed/regulated school-age child care programs in public school corporations, as authorized by IC 12-17-12, or a child care program that is also a not-for-profit organization, exempt from federal income taxation under Section 501(c) (3) of the Internal Revenue Code. Applicants may request a maximum of $40,000 per county. As outlined in IC 12-17-12-16, awarded Grants cannot exceed 90% of the Grantee’s total annual program operating costs. This is a cost reimbursement grant; thus, no funds will be disbursed in advance.

Programs must have been open and operating their school-age child care program for at least one (1) full year preceding the date of application for the School Age Child Care grant and remain in good standing through the entire grant period, and serve children between the ages of five (5) and fifteen (15) years which includes:

• Before and/or after school care offered during the regular school year or during the summer, if summer school is offered.
• Care provided during periods when school is not in session, excluding summer break
• Before and/or after school care for children who attend kindergarten (enrolled in either a full-day or half-day program).

The DoW Bone Marrow Failure Investigator-Initiated Research Award supports innovative research aimed at advancing the understanding and treatment of bone marrow failure. This funding opportunity encourages applications for translational and clinical studies, requiring preliminary data to strengthen proposals. Unique features include the ability for a partnering Principal Investigator to contribute to the research, thereby fostering collaboration while maintaining a focus on significant advancements in patient care.

The Clinical Data, Safety and Statistical Centers (CDSSC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance clinical research through comprehensive support. This includes statistical analysis, protocol development, and oversight of safety monitoring in studies related to asthma, autoimmune diseases, and transplantation. By coordinating these efforts, the program seeks to facilitate impactful research outcomes and improve public health outcomes through informed data-driven decisions.

The Translational Transplantation Tolerance Cooperative Study Group, supported by the National Institute of Allergy and Infectious Diseases, aims to advance transplant tolerance strategies that promote long-term graft survival without lifelong immunosuppression. This initiative focuses on developing, optimizing, and evaluating methods to induce immune tolerance in allogeneic transplants through collaborative efforts across multiple centers, utilizing translationally relevant models to ensure effective outcomes.

The NIAID aims to enhance our understanding of the interplay between chronic and infectious diseases through innovative precision systems biology research. By utilizing advanced technologies such as multi-omics and artificial intelligence, the initiative focuses on uncovering critical pathways that connect infections to chronic health issues. This multidisciplinary approach leverages longitudinal patient data to inform and improve prevention and treatment strategies, ultimately seeking to provide insights into disease progression and host-pathogen interactions.

The Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance research on asthma and related allergic diseases. This initiative fosters multi-center, multidisciplinary research to explore disease mechanisms and treatment responses. By promoting clinical trials and observational studies, the AADCRC seeks to advance understanding and improve interventions for conditions such as asthma and food allergies, ultimately benefiting public health.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing organ transplantation outcomes through the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. This initiative supports multicenter clinical trials and mechanistic studies related to heart, lung, kidney, liver, and intestinal transplants, as well as non-hematopoietic cellular transplantation. By exploring immune mechanisms and innovative therapies, the program aims to enhance the success and efficacy of organ transplantation.

The NIAID aims to enhance infectious disease research by supporting human microphysiologic systems (MPS) development. These in vitro platforms mimic human tissue functions, promoting drug and biological product development while reducing animal use. This initiative aligns with NIH’s commitment to innovative research practices and regulatory acceptance. By focusing on MPS in infectious disease contexts, NIAID seeks to streamline therapeutic advancements and establish robust human tissue models, addressing critical challenges in understanding and treating infections.

ASPCA Reimagining Racers: Grants for Adopting Out Retired Racehorses Grant

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and organizations actively participating in the warm-up ring (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) are invited to apply for a grant to support an increase in capacity and/or efficiency of programs aimed at adopting out retired Thoroughbred racehorses. 

Funding requests for this grant initiative should focus on:

Activities that increase capacity, decrease length of stay, reduce cost of care or increase efficiencies, and/or improve humane outcomes in other ways. Examples:

• Training programs
• Programs that engage new adopters and grow the market share for adoption
• Medical make-ready or rehabilitation with a focus on innovation and/or sustainability
• Collaborations with other equine industry organizations to increase support for retired racehorses

Proposals will be evaluated on their potential (within the 12-month grant term) to: 

• Increase capacity (the number of horses that can be rehabilitated, trained, and placed)
• Decrease length of stay
• Decrease cost of care
• Reduce risk, harm or suffering for retired racehorses

Requests may be for the creation of new programs or the expansion of existing programs. Programs that test innovative ideas are welcome.

Grant Amounts

Grants will generally range from $10,000-$40,000, with a maximum individual grant amount of $60,000. The total funding amount available for this grant opportunity is $200,000. 

Eligibility

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and active Warm-Up Ring participants (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) whose mission or operations focus significantly on serving retired Thoroughbred racehorses are eligible to apply for this grant opportunity. Adoption organizations must be up to date on reporting data biannually to the Equine Welfare Data Collective (EWDC). If you’re unsure about your eligibility, you may contact therighthorse@aspca.org to confirm before applying.   

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) was founded on the belief that animals are entitled to kind and respectful treatment by humans. We invite all voices to join us in working together to improve the lives of animals in need.

The ASPCA Right Horse Grants aim to enhance equine adoptions and support community equines by funding programs that boost shelter capacity or assist in keeping owned equines in their homes. Grants between $5,000 and $50,000 are available, with a total funding pool of up to $750,000. Eligible applicants include ASPCA Right Horse Adoption Partners and organizations committed to the welfare of retired Thoroughbred racehorses. Proposals should clearly outline the objectives and expected impacts.

Driving University Impact: Expanding the Public Exchange Network Grant

How the Public Exchange Network Works

No single university – even a large R1 – has enough faculty expertise available to meet the needs of every partner. The Public Exchange Network was designed to help universities work together seamlessly to build robust partnerships and generate more collective impact. Universities joining the network are independent but affiliated members, with full control over their own program and project portfolios. As a national network with local, on-the-ground capacity, Public Exchange Network members can also share approaches that work, scale solutions to common problems, and build cross-regional partnerships together. 

As an institutional partner in the Public Exchange Network, universities will build capacity to develop, test and implement solutions to the most urgent problems in their regions and beyond. Universities joining the Public Exchange Network get:

• The tools, templates and training they need to start right away;
• A shared brand they can plug into on day one;
• A network of faculty, past and potential partners and philanthropic relationships, benefitting everyone in the network. 

Public Exchange Network Expansion grants will cover 75-80% of the minimum estimated annual costs for two years to launch a new Public Exchange. To launch a Public Exchange, universities must have the following in place: (1) a staff executive director with experience launching and leading social impact partnerships, (2) a project seed fund, and (3) a modest operations budget. We also recommend some in-kind project management support from an existing university staff member. The grant includes a two-year Public Exchange Executive Director (ED) compensation subsidy of $300,000 to launch the Public Exchange on campus, and a 2-year license to use the Public Exchange brand. New Public Exchange Network members will also receive ongoing support and guidance from current Public Exchange leadership and staff at USC and WashU, including recruitment support and intensive training for hiring and onboarding an executive director, a sub-site on the Public Exchange website, incubation and project management support from current Public Exchange staff, and a suite of tools for developing and implementing Public Exchange projects.

The NIH Research Evaluation and Commercialization Hubs (REACH) program aims to facilitate the translation of biomedical discoveries into marketable products to enhance patient care. By funding five new academic entrepreneurship hubs, NIH will provide essential resources such as funding, mentorship, and expertise in product development. These hubs will address high-priority technologies and foster public-private partnerships, ultimately supporting the goals of federal research initiatives and addressing local health needs in underserved areas.

About Henry L. Hillman Foundation

Henry L. Hillman Foundation inspires, invests in, and leverages great ideas to improve the quality of life in Pittsburgh and southwestern Pennsylvania.

Backup Power When Your Community Needs It

The Powered & Prepared Initiative seeks proposals from nonprofit and municipal organizations in southwestern Pennsylvania for backup power solutions that allow those organizations to offer essential services during emergencies without disruption.

Southwestern Pennsylvania is increasingly impacted by severe weather events that cause widespread power outages and disruptions. The Powered & Prepared Initiative, supported by Henry L. Hillman Foundation, seeks proposals from nonprofit and municipal organizations for backup power solutions that allow those organizations to offer essential services during emergencies without disruption.

Building the Future Workforce Challenge

Awarding $5 million and the opportunity to test bold, tech‑forward solutions that strengthen the advanced manufacturing and industry technician workforce—today and for the future.

About the Challenge

Caterpillar knows preparing the workforce for the future is urgent. Communities, employers, and industry need new ways to close advancing skill gaps. The Building the Future Workforce Challenge invites fresh perspectives from all sectors to rethink training. Up to five teams will be awarded $1 million each for sustainable, tech‑forward solutions that strengthen today’s—and tomorrow’s—advanced manufacturing and industry technician talent pipelines.

What types of solutions are you looking for?

The Building the Future Workforce Challenge aims to identify, test, and scale innovative, sustainable solutions that will address today’s and tomorrow’s advanced manufacturing and industry technician skill gaps. A core requirement of any solution is that it remains relevant amid evolving technology—ensuring that breakthrough innovation and human potential rise together.

Strong proposals for Building the Future Workforce Challenge will meet four criteria outlined in the scoring rubric, and proposed solutions must focus on one or more of the following solution categories for Building the Future Workforce Challenge: