Best Grants for 501(c)(3) in Massachusetts

UniBank Community Giving is dedicated to enhancing local communities through charitable contributions. With over $750,000 allocated annually, it supports initiatives in youth development, community development, affordable housing, and environmental concerns. Established in 2018 with a foundation of $2 million, UniBank aims to fortify its commitment to community service. Organizations with proven success and collaboration efforts are encouraged to apply, ensuring timely funding decisions for impactful projects.

Scholarships are available to graduating high school seniors. Applications are accepted from mid-November until mid-March. Scholarship award recipients will be announced at the high school awards ceremony. 

Van Cott Family Memorial Scholarship

Established in memory of Kermit Van Cott and his son Forrest to provide tuition assistance to a graduating Senior from one of the High Schools in Susquehanna County, with priority given to Blue Ridge, who will major in Landscape Architecture, Environmental Science, Environmental Engineering, Horticulture, Botany, Forestry, or Agriculture and who will matriculate at college or a post-secondary degree program.

The Empathy Building Initiative, led by Acton Family Giving, seeks to foster partnerships with organizations aligned with its mission. While currently not expanding its portfolio, it invites inquiries from potential partners. Eligible organizations must hold 501(c)3 status and align with specific giving areas. The initiative focuses on a national or broad reach and evaluates grant applications based on alignment and conversation. For more details, potential partners are encouraged to review the grants list available on their website.

The Yocha Dehe Community Fund, established by the Yocha Dehe Wintun Nation in 2000, supports initiatives that strengthen communities throughout Yolo County and beyond. With nearly $40 million in grants, the Fund prioritizes projects in health, education, Native arts, and environmental protection. The Tribe's commitment involves active participation in the grant process, ensuring impactful partnerships with various organizations. New applicants must register on the grant portal and submit a letter of inquiry to be considered for funding.

The NIH R25 program aims to enhance inclusivity in research education by supporting activities that encourage individuals from diverse backgrounds to pursue careers in substance use and addiction sciences. This initiative focuses on skills development courses and research experiences, particularly targeting underrepresented groups in biomedical and behavioral sciences. Applications are due by 5:00 PM local time of the applicant organization, with optional Letters of Intent encouraged 30 days prior to the full proposal deadline.

The Fehr Graham Scholarship provides financial support for students pursuing careers in engineering, landscape architecture, land surveying, geology, hydrogeology, assessment and remediation, and environmental health and safety. Applicants must reside within fifty miles of a Fehr Graham office and intend to enroll in their first year of post-secondary education. This scholarship is renewable for up to three years, contingent upon maintaining a 2.8 GPA. It aims to enhance educational opportunities in the communities served by Fehr Graham.

The United Company Foundation, established in 1986, provides grants to support charitable organizations in Bristol, VA, Bristol, TN, and Southwest Virginia. This private non-profit focuses on areas such as food, shelter, education, the arts, health, and youth services, emphasizing fiscal responsibility and innovative approaches. By prioritizing accountability and measurable outcomes, the Foundation aims to foster long-term improvements in the community it serves.

Community Development Block Grant – Public Services

This grant opportunity is intended to connect low and moderate-income (LMI) Boston residents to a continuum of education, workforce development, and economic security programs to increase their capacity to obtain career-oriented employment leading to economic stability.

Grant Program Description:

Each year, the City of Boston receives Community Development Block Grant (CDBG) funds from the U.S. Department of Housing and Urban Development (HUD) through the Mayor’s Office of Housing. The funds are primarily used for affordable housing and economic development activities. However, up to 15% of the funds can be used for “public services” related to economic development. As the City’s workforce development agency, the Office of Workforce Development (OWD) manages this portion of the funding on behalf of the Mayor’s Office of Housing. 

The public services component of the CDBG funds provides services for low-income individuals and families with the goal of moving them out of poverty towards economic security. In anticipation of this RFGA, OWD released a set of policy principles. For the Fiscal Year (FY) 2027, OWD will continue to prioritize programs and services that fit within this range of long-term economic stability and growth, including but not limited to: Child Care, Health care, Job Training, Education Programs, Public safety services, Fair Housing Activities, Services for senior citizens, Services for homeless persons, Drug abuse counseling & treatment. 

As a reminder, the policy principles highlight the need to promote economic stability and mobility. These core beliefs shape strong programs:

• Investment in programs that place individuals on a continuum of quality education, training, workforce development, and economic security. This continuum is defined as high school diplomas/HiSET attainment, matriculation into post-secondary education or industry-recognized training programs, placement into jobs with demonstrated career paths, and/or access to income maximization programs that stabilize individuals and families with barriers. 
• A high degree of coordination of wrap-around support services, which address a wide range of individual and family needs. These can include, but are not limited to, financial literacy, ESOL/Adult Basic Education, income and/or benefits maximization, mental health, childcare, transportation, and individual case management. 
• The use of partnerships and collaborations is strongly encouraged to ensure that there are no gaps in a continuum of programs and supportive services to address a wide range of needs.
• The use of work-based training that provides maximum opportunities for participants to gain employment skills that meet employer needs.

Total Amount Available for Grant Program: Approximately $2,100,000.

Grant awards are subject to the availability of appropriated funds. Any oral or written representations, commitments, or assurances made by the Department or any other City representatives are not binding. Recipients should verify funding before beginning performance.

Award Amount per Grant per Organization: OWD anticipates grants ranging in size from $50,000 to $95,000.

Avnet Cares Grants support nonprofit organizations in the U.S., Canada, and Mexico that focus on making a positive impact in their communities. Grants are available for initiatives in STEM, environmental sustainability, and assistance for communities in crisis. Eligible nonprofits must have been operational for at least three years. The program prioritizes organizations that serve areas where Avnet has significant operations, fostering community growth and development.

The Quadratec Cares 'Energize The Environment' Grant Program is dedicated to supporting individuals and organizations in the U.S. focused on environmental improvement. With two grants of $3,500 awarded annually, the program encourages initiatives like trail restoration and community educational projects. This grant aims to empower passionate individuals to enhance environmental awareness and stewardship, ensuring a healthier planet for future generations.

The Adams Cheshire Educational Partnership (ACE) Grant aims to enhance educational experiences for students and teachers in the Adams-Cheshire Regional School District. This grant supports projects that promote excellence in education, prioritizing volunteer-driven proposals. Eligible applicants include students, teachers, and community members, while projects may range from independent studies to professional development. Importantly, ACE does not fund salaries or replace public school funding, ensuring that resources are directed towards enriching educational initiatives.

The Philadelphia Chromosome Negative Myeloproliferative Neoplasms (MPN) Grant, offered by the Patient Advocate Foundation, provides crucial financial assistance to patients facing this cancer type. It covers out-of-pocket healthcare costs, including medication copays and insurance premiums, ensuring those affected can access necessary treatments. With a focus on personalized case management, the foundation has supported millions in navigating their healthcare needs, emphasizing the importance of timely and affordable care for patients diagnosed with MPN.

This funding opportunity aims to support urgent research evaluating policies that impact health behaviors related to obesity. It is designed for studies that can only be performed with expedited review due to the time-sensitive nature of the research. Applications must demonstrate a compelling need for immediate funding to explore new policies or programs affecting dietary habits and physical activity, with the expectation that successful proposals will receive funding within four months.

The David Moses Bridges Scholarship honors the legacy of a renowned Passamaquoddy artist and activist, providing essential support for individuals dedicated to the preservation of Wabanaki culture, traditional arts, and environmental stewardship. This scholarship aims to foster connections between master artists and apprentices, promote research on David's impactful life and work, and protect culturally significant natural spaces. It empowers artists and scholars to continue the vital work of preserving indigenous knowledge and practices for future generations.

The Gamma Mu Foundation, established in 1988, aims to support the LGBT community in rural and underserved areas through various grants. Initially focused on HIV/AIDS projects, it now funds scholarships and services for diverse LGBT subpopulations. With over $2 million awarded, the Foundation prioritizes initiatives that enhance community support, public education, and health programs. It emphasizes projects that build organizational capacity and provide essential services where resources are limited, ensuring ongoing support for vital health and social services.

Sun Life’s Health Access Grant Program aims to enhance access to health services, specifically targeting diabetes and oral health in local communities. With funding options ranging from $25,000 to $100,000, this program supports 501(c)(3) charities focused on diabetes prevention, management, and oral health care. By fostering access to essential health services, Sun Life is committed to building healthier communities and addressing health disparities faced by underprivileged populations.

The Educational Incentive Award Application by the Cooley’s Anemia Foundation aims to support children of individuals with severe thalassemia in pursuing their educational and career aspirations. With a total funding of $10,000 for the 2025-2026 school year, awards range from $500 for two-year programs to $1,000 for higher degree studies. Eligible applicants must be diagnosed with specific thalassemia types and provide necessary documentation, including a 250-word essay detailing their educational goals.

Loene Pooler Guthrie Scholarship Fund

The Loene P. Guthrie Scholarship fund benefits music students in Benton, Linn, and Lincoln counties who plan to engage in the teaching of piano, voice, and orchestral music.

This scholarship fund promotes the teaching of piano, voice and orchestral music by aiding music students in Benton, Linn, and Lincoln Counties who plan to engage in the teaching of piano, voice, and orchestral music. Students who will graduate from Linn, Benton, or Lincoln County high schools or graduates of those high schools currently studying music at an institution of higher learning may apply. The Linn-Benton Chapter of the Oregon Music Teachers Association reviews the applications and selects individuals to perform at an audition open to the public.

The RMEF Grant Program lies at the core of advancing our mission.

RMEF established the program in 1986 to provide financial and logistical support to projects that align with our priorities and goals. Grant funds raised by RMEF members, volunteers and generous donors from across the country translate into significantly more conservation accomplishment when matched with partner funds. The RMEF Grant Program also aims to build recognition for RMEF’s work, grow engagement, and boost local fundraising efforts.

Governed by clear guidelines and criteria, the RMEF Grant Program seeks to foster meaningful collaborations and long-term impacts in the conservation of natural resources and outdoor traditions. Grant project partners include federal, state, local, and tribal wildlife and land management agencies, private landowners and local stakeholders, sportsmen and women, and conservation organizations, universities, foundations and the outdoor industry. Eligible projects primarily focus on habitat stewardship, land conservation and access, wildlife management, and hunting heritage.

We support organizations recognized by the Internal Revenue Service (IRS) as a 501(c)3 entity, federal, state, local, or tribal government entities, sportsmen’s organizations, or educational institutions. All applicants must have a Federal Employer Identification Number (EIN) issued by the IRS. RMEF does not offer grants to individuals.

Hunting Heritage

Ensuring our hunting heritage is central to RMEF’s mission. Hunters—America’s first conservationists—remain the driving force behind wildlife conservation. RMEF funds hunting heritage and conservation education to help more people experience the outdoors, learn the skills of hunting, and carry forward the traditions that define big game country, including outdoor skills programs/events, hunter or conservation outreach, mentored hunts, and other similar activities.

The Thalassemia Patient Incentive Award, sponsored by the Cooley’s Anemia Foundation, aims to support thalassemia patients in pursuing their educational and career aspirations. Awards ranging from $250 to $2,000 will be granted to students at various academic levels, with applications due in March 2026. This initiative not only encourages academic growth but also fosters a positive outlook among patients living with thalassemia, underscoring the Foundation's commitment to improving their quality of life.

The Chemical Countermeasures Research Program (CCRP) Initiative aims to support vital research on the harmful effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids, including fentanyl and its combinations. This funding opportunity encourages studies that enhance understanding and mitigation strategies for these substances, focusing on both immediate and long-term health impacts. Applications are due by 5:00 PM local time, with optional Letters of Intent accepted 30 days prior to the proposal deadline.

The Dean John A. Knauss Marine Policy Fellowship offers a unique opportunity for early career professionals to engage in marine and Great Lakes science and policy within the U.S. government. This one-year, paid fellowship encourages graduate students from accredited programs to explore impactful coastal resource issues. Interested applicants should connect with their local Sea Grant program or the National Sea Grant Office for guidance, especially if they are from Massachusetts, to ensure a competitive application.

The Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use initiative aims to enhance prevention services for infectious diseases among people who use drugs (PWUD). It encompasses two components: a biennial survey to assess service gaps and capacity, and increased support for testing and treatment services. The initiative seeks to improve data utilization in service provision, ultimately increasing testing for HBV, HCV, and HIV, and ensuring more PWUD engage in treatment and care.

Headstream Accelerator 2026

Accelerator Application Cohort VI

The Headstream Accelerator supports entrepreneurs from all backgrounds in scaling digital solutions that improve the mental well-being of teens at risk, with a focus on the education and healthcare sectors. Our four-month, virtual-first program is designed for early-stage innovators, helping them strengthen their business models, refine their value propositions, and build the foundation for sustainable growth and meaningful impact.

Benefits:

• $30,000 non-dilutive stipend 
• Partnership with youth from Headsteam’s Youth Co-Creator Club to gain insights on cultural relevance, age-appropriateness, and user experience, ensuring your solutions resonate deeply and effectively with the next generation 
• Access to a network of expert advisors, connect with a community of founders, and engage with potential investors and capital providers 
• Access to one-on-one and group coaching sessions with our partner, FounderWell

Participant Expectations:

• Attend all activities, including virtual cohort and youth co-creation sessions, advisor calls, and an in-person kickoff event from July 28–30, 2026
• Commit 2–5 hours weekly during the program, including virtual sessions, advisor network office hours, guide calls, and more
• Embed youth voices throughout your product development

The Ceres Foundation Grant focuses on supporting nonprofit organizations that enhance education and career pathways for historically underserved communities. With a commitment to measurable outcomes, the foundation prioritizes initiatives in college access, career pathways, and family strengthening. While currently not accepting new partnerships until Summer 2025, existing grantees can submit proposals for continued support. Grants typically average $70K annually, aimed at fostering long-term collaborations and capacity building.

The Rural Opioid Technical Assistance Centers program aims to provide essential training and technical assistance to combat opioid and stimulant misuse in rural areas. With 10 Regional Centers and a National Coordinating Office, the initiative focuses on high-quality prevention, treatment, and recovery support services for substance use disorders. This program anticipates awarding 11 new grants to enhance community health and safety in addressing polysubstance use challenges.

The Michael & Susan Dell Foundation provides grants to organizations focused on improving the lives of children in urban poverty in the U.S., India, and South Africa. They prioritize projects in education, health, and family economic stability. Grants typically do not exceed 25% of a project's budget or 10% of an organization's annual expenses. The foundation seeks to partner with organizations already making an impact, ensuring funding supports impactful social enterprises.