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Best Large Grants for Nonprofit Organizations in Massachusetts

Find the perfect Large Grants for Nonprofit Organizations in Massachusetts on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in Massachusetts in the United States.

10,000+

Available grants

$2.65B

Total funding

$5K

Median grant

10,000+ grants
$2.65B total
$5K median

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Filters

9,887 Results based on applied filters

Layton Family Foundation Scholarship

The Community Foundation of Shelby County
Private
United States
US $1,200

The Community Foundation of Shelby County

Our Mission

To inspire donor generosity and transform it into meaningful, lasting impact through charitable gifts.

Our Vision

To be the primary partner for donors who want to advance the community’s quality of life and capacity for excellence.

Layton Family Foundation Scholarship

Selection based upon (in order of priority):

  • Academic ability and an additional essay on a designated topic, and recommendations.

Awards

  • One $1,200 scholarship
Education - Higher Education Career / College Preparation Vocational & Trade Education

Fostering Education Scholarship Fund

Cobb Community Foundation Inc
Private
United States
US $2,000 - US $3,000
The Fostering Education Scholarship Fund, established by Village Connection and Innovative Fitness, provides scholarships of $2,000-$3,000 to eligible students who have aged out of Georgia's foster care system. Applicants must be U.S. citizens or legal residents, high school seniors or recent graduates, and have a minimum GPA of 2.5. This initiative aims to empower these students with the financial support they need to pursue higher education, fostering a brighter future for the community.
Education - Higher Education Education - High School Academic Scholarship Programs

H20 For Life: Mini-Grant

H20 For Life
Private
United States
Up to US $500

Kickstart Your Project with a Mini-Grant

At H2O for Life, we never want finances to be a barrier to participating in a service project. The H2O for Life Mini-Grants are meant to be a supportive resource for teachers and students who want to kick-start their projects with us. Mini-grants of up to $500 will be awarded to support teachers and students with the necessary funds for their service-learning programs.

Our Mission

H2O for Life offers a service-learning opportunity designed to engage, educate and inspire youth to take action to solve the global water crisis by raising awareness and funds to support implementation of water, sanitation and hygiene education projects for global partner schools.

Since 2007, nearly 1 million students from H2O for Life schools have supported water, sanitation, and hygiene education projects for partner schools in the developing world.

What is H2O for Life doing to address the global water crisis?

H2O for Life’s service-learning opportunities are designed to engage, educate, and inspire youth to become global citizens. Our innovative school-to-school approach helps young people develop a concern for others by taking a major global crisis and scaling it down to a manageable size — one water project in the developing world.

Through the service-learning opportunity we provide, students learn that they can make a tangible difference for the students in their partner school.

Sanitation & Clean Drinking Water Education - Middle School

Professional Nurses of Southwestern PA Scholarship Fund

Pittsburgh Foundation
Private
United States
Unspecified amount
The Professional Nurses of Southwestern PA Scholarship Fund, established by The Pittsburgh Foundation, supports nursing education for students in nine counties of southwestern Pennsylvania. This scholarship aims to assist those pursuing a Pre-Licensure RN, BSN, Master's, PhD, or DNP programs. Eligible applicants must have completed one semester in a nursing program and maintain a minimum GPA of 3.0. The fund continues the legacy of the Pennsylvania State Nurses Association, promoting leadership and service in nursing.
Education - Higher Education Academic Scholarship Programs Nursing

Pocket Nurse Scholarship Fund

Pittsburgh Foundation
Private
United States
Approximately US $5,000
The Pocket Nurse Scholarship Fund, established by Pocket Nurse at The Pittsburgh Foundation, provides financial assistance to students pursuing education in Allied Health, Nursing, and Nursing Faculty. This initiative highlights the Foundation's commitment to supporting local students, especially those from marginalized backgrounds, as they strive to achieve their academic and career goals. With a minimum GPA requirement of 3.5, the program aims to empower the next generation of healthcare professionals.
Education - Higher Education Nursing Academic Scholarship Programs

MrBallen Foundation: Rapid Response Grants

Mrballen Foundation Inc
Private
United States
Unspecified amount

Rapid Response Grants 

Emergency funding after mass tragedies.

In the wake of tragic mass events, such as shooting, speed matters. Our Rapid Response Grants provide expedited funding to victims and their families when time is of the essence. These grants ensure that families aren’t left waiting for critical support when they need it most.

  • Awarded swiftly after mass casualty events
  • Designed to provide urgent, compassionate support in crisis situations
Disaster Relief / Humanitarian Aid Family Services Gun Violence Prevention

Lipsky-Whittaker LGBTQ Scholarship

Southcoast Community Foundation
Private
United States
Unspecified amount
The Lipsky-Whittaker LGBTQ Scholarship, established by the SouthCoast Community Foundation, provides financial support to graduates from New Bedford area high schools who identify as LGBTQ+. Applicants must be under 24 years old and enrolled in or accepted to an accredited college. This scholarship aims to empower students committed to addressing LGBTQ+ issues in their communities, contributing to a more inclusive society.
Academic Scholarship Programs College Success / Persistence LGBTQIA+ Services

Gene Robb Journalism Scholarship

The Community Foundation for the Greater Capital Region
Private
United States
Unspecified amount
The Gene Robb Journalism Scholarship, offered by The Community Foundation for the Greater Capital Region, recognizes the significant contributions of former Times Union publisher Gene Robb to journalism. It is designed for students with a demonstrated interest in journalism, requiring them to submit samples of their work. This scholarship supports both high school and college students aiming to excel in the field, empowering them to pursue their educational goals.
Education - Higher Education Journalism Academic Scholarship Programs

DoW Bone Marrow Failure, Resource Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,250,000
The FY26 Bone Marrow Failure Research Program's Resource Development Award aims to create a multiomic atlas from human bone marrow failure samples. This resource will be open-access, providing essential data for researchers and clinicians to enhance their understanding of bone marrow failure diseases. A comprehensive Data Resource Sharing Plan is required to ensure timely availability of the developed resource, fostering collaboration within the scientific community.
Skeletal Diseases Myeloma

Weiss Writing Prize

American College Health Foundation
Corporate
United States
US $1,500
The Weiss Writing Prize, established by the American College Health Foundation in 2010, aims to enhance mental health care quality for college students. It honors the lead author of a significant publication addressing student retention programs for those with mental health challenges. By fostering innovative and effective solutions, this prize encourages the dissemination of impactful research among American College Health Association members, ultimately contributing to the well-being and success of students across campuses.
Wellness & Healthy Living Education - Higher Education Mental Health & Psychiatric Diseases

Kids' Chance of Massachusetts Scholarship- Initial Application

Kids' Chance of Massachusetts
Association/Society
United States
Up to US $5,000
Kids' Chance of Massachusetts offers scholarships to children of workers who have been severely injured or killed in workplace accidents. This 501(c)(3) non-profit organization awards funds based on financial need, with applications accepted annually. Eligible students must be dependents aged 17-22, enrolled full-time in post-secondary education, and demonstrate financial need. Renewal applications are available for previous recipients who maintain satisfactory academic progress.
Academic Scholarship Programs Occupational Health & Safety Education - Higher Education +1 more

In God We Trust, Mitchelle T. Savage Memorial Scholarship Fund

Battle Creek Community Foundation
Private
United States
Unspecified amount

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

In God We Trust, Mitchelle T. Savage Memorial Scholarship Fund

The In God We Trust, Mitchelle T. Savage Memorial Scholarship was established to provide educational opportunities beyond high school for Battle Creek area graduates or graduating seniors. Eligible recipients will be graduating seniors from Battle Creek area public and private schools who will be attending a college that is a member of the Council for Christian Colleges and Universities.

Education - Higher Education Christianity Career / College Preparation

R.K. Mellon Family Scholarship/Ligonier Valley Endowment Fund

Pittsburgh Foundation
Private
United States
US $5,000

The Pittsburgh Foundation provides scholarship opportunities for students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four–year universities, graduate schools, and career/technical schools.

R.K. Mellon Family Scholarship/Ligonier Valley Endowment Fund

The R.K. Mellon Family Scholarship/Ligonier Valley Endowment Fund was established at The Pittsburgh Foundation to provide scholarships to students in the Ligonier Valley School District. 

  • Average Award: $5,000
  • Award Type: Single-Year Award
Education - Higher Education Volunteerism & Philanthropy Vocational & Trade Education

DoW Parkinson’s, Investigator-Initiated Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The FY26 Parkinson’s Research Program Investigator-Initiated Research Award supports innovative, multidisciplinary research projects aimed at advancing the understanding and treatment of Parkinson’s disease. The award encourages collaboration among multiple principal investigators, requiring preliminary data and allowing clinical trials to enhance research outcomes. This initiative is vital for fostering impactful discoveries within the four specified focus areas of the program, ultimately improving patient care and management.
Parkinson’s Disease

Arthritis Foundation: Clinical Fellowship RFP

Arthritis Foundation
Private
United States
Up to US $300,000
The Arthritis Foundation's Clinical Fellowship RFP aims to address the rheumatology workforce shortage by inviting applications from institutions with clinical training programs. It encourages innovative training approaches to prepare future rheumatologists for the evolving needs of the arthritis community. Funding includes $150,000 for a two-year adult fellowship, $225,000 for a three-year pediatric fellowship, and $300,000 for a four-year Med-Peds fellowship, all designed to enhance access to specialized care.
Arthritis

Craft Artists Emergency Relief Grant

Craft Emergency Relief Fund Inc
Private
American Samoa, Guam +4 more
US $1,000
The Craft Artists Emergency Relief Grant provides $3,000 to U.S.-based individual craft artists aged 18 and older who are facing recent, unforeseen emergencies. Established by the Craft Emergency Relief Fund (CERF+) in 1985, this grant aims to empower artists during critical times, allowing them to use the funds as needed for recovery. Applications are accepted on a rolling basis, ensuring timely support for artists in distress.
Folk Art / Traditional Art Visual Arts Textile & Fiber Arts

CERF: Artist Get Ready Grant

Craft Emergency Relief Fund Inc
Private
American Samoa, Guam +4 more
Up to US $1,000
The CERF: Artist Get Ready Grant offers up to $1,000 to craft artists for safeguarding their studios and preparing for emergencies. Priority is given to underrepresented artists, including BIPOC and folk/traditional artists. Eligible activities encompass studio safety upgrades and disaster readiness. Applicants must be 18 years or older, residing in the U.S. for two years, and not have received this grant in the previous year. Funds must be used within six months, with outcomes documented for CERF+.
Folk Art / Traditional Art Visual Arts Textile & Fiber Arts

Paul J. Baum Fund Scholarship

Pittsburgh Foundation
Private
United States
Unspecified amount
The Paul J. Baum Fund Scholarship, established by The Pittsburgh Foundation, supports college and graduate students pursuing degrees in Music. As one of the oldest community foundations in the U.S., The Pittsburgh Foundation has been dedicated to improving quality of life since 1945. This scholarship opportunity is available to both undergraduate and graduate students who meet eligibility criteria, including a minimum GPA of 2.5 and participation in music programs.
Education - Higher Education Academic Scholarship Programs Music Education

Jack Ford Shelby Scholarship Fund

Communities Foundation of Texas
Private
United States
Up to US $5,000
The Jack Ford Shelby Scholarship Fund, established in 1953, supports graduating seniors from Littlefield High School in Texas with scholarships up to $5,000 for pursuing a baccalaureate degree at accredited colleges or universities. This initiative aims to enhance community health and equity by investing in the education of local students, ensuring they have the necessary resources to succeed academically and contribute positively to society.
Education - Higher Education Education - High School Academic Scholarship Programs

Ben J. Lipps Research Fellowship Program

American Society of Nephrology Foundation
Corporate
Central America, North America
Up to US $100,000
The Ben J. Lipps Research Fellowship Program supports nephrology fellows in conducting original research on kidney biology and disease. Each fellow receives $50,000 annually for up to two years, with a limit of two applications per sponsor per cycle. Candidates must hold an MD, DO, PhD, or equivalent and commit to 75% research time. The program encourages applications from underrepresented minorities in medicine, fostering diversity in nephrology research.
Kidney Diseases

ASN: Pre-Doctoral Fellowship Award Program

American Society of Nephrology Foundation
Corporate
Central America, North America
Up to US $60,000
The ASN Pre-Doctoral Fellowship Award Program aims to support PhD students conducting original research in kidney biology and disease. Each fellowship provides $30,000 annually for two years, contingent upon satisfactory progress reports. Eligible candidates must be graduate students in accredited programs, committed to kidney-focused research, and must engage with ASN as members. The program encourages applications from underrepresented groups in medicine, fostering diversity and innovation in nephrology research.
Kidney Diseases

Clinical Scientist in Nephrology Fellowship

American Kidney Fund
Private
United States
Up to US $180,000
The Clinical Scientist in Nephrology Fellowship, funded by the American Kidney Fund, supports nephrologists pursuing academic careers. This prestigious program enhances training and promotes clinical research aimed at improving patient care and outcomes for those with chronic kidney disease. With a funding maximum of $90,000 per year for two years, it covers salary and training-related expenses, fostering the next generation of leaders in nephrology.
Kidney Diseases

Mary Agnes Powers Scholarship Fund

Pittsburgh Foundation
Private
United States
Approximately US $1,000
The Mary Agnes Powers Scholarship Fund, established by the Pittsburgh Foundation, supports nursing students from several Pennsylvania counties. This scholarship honors Mary Agnes Powers and is awarded based on academic merit, financial need, and enrollment in nursing programs. Eligible candidates must reside in designated counties, maintain a GPA of 3.0 or higher, and be entering their final year of nursing education. The scholarship aims to empower local students in their pursuit of nursing careers.
Education - Higher Education Academic Scholarship Programs Nursing

Rheumatoid Arthritis Research Request for Proposals

Arthritis Foundation
Private
United States
Up to US $450,000
The Arthritis Foundation is inviting proposals for research aimed at understanding and predicting the progression of rheumatoid arthritis (RA). This includes identifying risk factors and mechanisms to prevent or slow the onset of RA. The program encourages innovative studies from early and mid-career investigators affiliated with U.S. institutions, with funding options that support both pilot and large research awards. The ultimate goal is to enhance outcomes for RA patients.
Arthritis

Catalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development (R61/R33 - Clinical Trial Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Up to US $4,466,000
The NHLBI Catalyze program aims to transition basic science discoveries into effective treatments for diseases under the NHLBI mission. This initiative supports early-stage product definition, prototype design, and assay development for HLBS disorders. The R61 phase focuses on initial designs and experimental setups, while the R33 phase extends support for prototype testing and user feedback. Successful completion prepares products for in vivo testing, enhancing health and societal outcomes with NIH and other support.
Respiratory Diseases & Systems Sleep Medical Technology, Devices, and Equipment

James S.T. Yao Resident Research Award

Society for Vascular Surgery (SVS) Foundation
Association/Society
Canada, United States
US $5,000
The James S.T. Yao Resident Research Award encourages early-career physicians in the U.S. and Canada to engage in groundbreaking research on vascular diseases and therapies. Awarded by the SVS Basic and Translational Research Committee, it includes a $5,000 prize, a presentation opportunity at the Vascular Annual Meeting, and a subscription to the Journal of Vascular Surgery. This award honors the legacy of Dr. James S.T. Yao, a prominent figure in vascular research.
Human Anatomy Cardiovascular Diseases & Systems

Kellogg Company-Tony McGee Scholarship Fund

Battle Creek Community Foundation
Private
United States
Unspecified amount

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

Kellogg Company-Tony McGee Scholarship Fund

The Kellogg Company - Tony McGee Scholarship was specifically established for the purpose of providing scholarships to minority graduates/graduating seniors from the greater Battle Creek area seeking educational opportunities beyond high school. Scholarship awards will support associate and bachelor’s degree programs, as well as certificate and apprenticeship programs.

Education - Higher Education Career / College Preparation Apprenticeship & Internship Programs

Large Grants for Nonprofit Organizations in Massachusetts Highlights

Looking for large grants for nonprofit organizations in Massachusetts?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Massachusetts recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Massachusetts

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Large Grants for Nonprofit Organizations in Massachusetts grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

95 Large Grants for Nonprofit Organizations in Massachusetts over $25K in average grant size

75 Large Grants for Nonprofit Organizations in Massachusetts over $50K in average grant size

60 Large Grants for Nonprofit Organizations in Massachusetts supporting general operating expenses

200+ Large Grants for Nonprofit Organizations in Massachusetts supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Massachusetts?

Most grants are due in the first quarter.

Q1
32.0%
Q2
24.4%
Q3
18.8%
Q4
24.8%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Massachusetts?

Grants are most commonly $26,875.

$250 $250 Min.
$26,875 $26.9 K Median
$413,560 $413.6 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Massachusetts?

Grants are most commonly $124,010.

$124,010

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Massachusetts year over year?

In 2024, funders in Massachusetts awarded a total of 105,825 grants.

2022 103,608

2023 102,118

2024 105,825

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Massachusetts given out in Massachusetts, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Massachusetts changing over time?

Funding has increased by 9.89%.

2022 $14,522,602,699

2023 $11,906,472,240
-18.01%

2024 $13,083,681,605
9.89%

Massachusetts Counties That Receive the Most Funding

How does grant funding vary by county?

Suffolk County, Middlesex County, and Norfolk County receive the most funding.

County Total Grant Funding in 2024
Suffolk County $7,016,988,269
Middlesex County $2,770,808,615
Norfolk County $554,651,103
Essex County $369,041,706
Worcester County $299,030,165