Best Large Grants for Nonprofit Organizations in Massachusetts

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Drs. Ruth & John Carney & Irene Carney Kendrick Memorial Scholarship

This scholarship has been made possible by the generosity of Dr. John Carney, who established the Drs. Ruth & John Carney & Irene Carney Kendrick Memorial Scholarship of the Community Foundation for Mason County.

The Carney’s love of Ludington ran deep, and they served the Ludington community through their family medical practice for over 42 years. Dr. Carney valued education and wanted to help others achieve their dreams. John’s encouraging spirit lives on through this scholarship, established in memory of his first wife and their late daughter, to create opportunities for adult students, students pursuing postgraduate degrees, or those facing barriers to getting a college degree.

About Pfizer Grants

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

There remains a scientific gap in understanding of the role of anti-TFPImediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Project Types and Area of Interest

Potential applicants are encouraged to identify and address preclinical/basic science data generation for TFPI modulation/rebalancing in their local setting. This may include:

• Rare bleeding disorders which arise from deficiencies in different clotting factors or pathway components but converge on a common functional endpoint which is an impaired thrombin generation (e.g., Factor II, Factor V, Factor VII, Factor X and Factor XI deficiencies, as well as von Willebrand disease).
• Other diseases such as Glanzmann's thrombasthenia (GT) that have a distinct pathophysiological mechanism.
• Other rare bleeding disorders whose mechanisms are not well understood (e.g., Bleeding Disorder of Unknown Cause, BDUC).

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Emily & Frank Smiddy Scholarship

This scholarship has been made possible by the generosity of Emily & Frank Smiddy who established the Emily & Frank Smiddy Scholarship Fund of the Community Foundation for Mason County.

Frank Smiddy, former owner of ProAct Environmental Services located in Ludington, has always had a passion for STEM-related learning and wants to give back to the community where he owns his business. He and his wife, Emily, wanted to leave a legacy of students going into this field the best chance possible to get their college education with as little debt as possible, so they established the Emily & Frank Smiddy Scholarship Fund. It is their hope that students receiving this scholarship will be motivated, when they are financially able, to give back to the community to help others see success.

The Hudson Physicians Scholarship, offered by the St. Croix Valley Foundation, supports graduating seniors from high schools in St. Croix or Pierce Counties who are pursuing a career in healthcare. Applicants must have a GPA of 3.0 or higher, and financial need will be considered. This scholarship reflects the Foundation's commitment to fostering local talent and enhancing community well-being by investing in future healthcare professionals.

The Small Business Transition Grant for New Entrepreneurs aims to support early-career scientists transitioning into entrepreneurship. Funded by the NIH and CDC, this initiative encourages small business concerns to apply for SBIR Phase I and Fast-Track grants. Key components include research funding, entrepreneurial training, and mentorship. Potential applicants are urged to prepare their projects and identify mentors, ensuring the inclusion of experienced personnel committed to the project. This opportunity is tailored for first-time Principal Investigators.

The AE Foundation Community Grants aim to support US and Canadian non-profit organizations focused on enhancing the mental health and well-being of young people. By funding local programs, the AE Foundation empowers teens and young adults to embrace authenticity and build a brighter future. Eligible organizations must be certified 501(c)3 non-profits or registered charities, and grant funding should be utilized within 365 days of receipt. This initiative reinforces the importance of mental health in today's society.

The Frank Chaney Memorial Scholarship, offered by the St. Croix Valley Foundation, supports graduating seniors from Hudson or Stillwater area high schools pursuing any field within the arts. This scholarship aims to empower young artists and facilitate their educational journeys at any college of their choice, reflecting the Foundation's commitment to enhancing community impact through local generosity and support for the arts.

The Christina Sue Lilja Resource Grants support agricultural literacy by providing funds for educators to purchase resources from the Ag Foundation store. In 2025, 100 educators will receive $100 in store credits, selected randomly if applications exceed this number. This initiative, backed by the CSL Foundation, honors Christy Lilja's legacy of advocating for agricultural education. The grants aim to enhance classroom resources and improve students' understanding of agriculture, ensuring access to accurate information.

The Headache Medicine Fellowship aims to enhance training in headache medicine by supporting programs focused on diversity, equity, and inclusion. Targeting regions with workforce challenges, the fellowship encourages clinical practice, research, and education to address healthcare disparities. Preference is given to institutions that serve underserved populations and demonstrate a commitment to mentorship and expert guidance for fellows. This initiative seeks to improve understanding and treatment of headache conditions.

The Columbus Hilltop Lions Community Service Scholarship Fund, established by The Columbus Foundation in 1943, aims to support high school seniors from the Hilltop area of Columbus who demonstrate a strong commitment to community service. The scholarship offers $2,000 over two years to eligible candidates who have completed at least 30 hours of volunteer service. This initiative reflects the foundation's long-standing dedication to enhancing the quality of life in central Ohio.

The Jefferies-Park Scholarship, established in 1988 by Evelyn Jefferies-Park, honors her commitment to education. It supports graduating seniors from Ord High School, Nebraska, who are in the top 15% of their class and plan to pursue a four-year degree. This scholarship reflects the legacy of generosity fostered by the Lincoln Community Foundation, which has provided over $606,000 in scholarships to local students in 2025 alone.

The Ian Van Heyde Memorial Culinary Scholarship Fund, established by Stephen and Nancy Van Heyde, honors their son Ian, a culinary arts student from Whetstone High School. This fund provides scholarships to students pursuing postsecondary education in culinary arts, food management, or restaurant management. Award amounts start at $1,500, aimed at supporting talented individuals from central Ohio's public culinary programs. Previous recipients are encouraged to apply again, fostering continued growth in the culinary field.

The Emily Hall Tremaine Exhibition Research Grant supports innovative projects that explore contemporary art in new frameworks. With a focus on education in the United States, the foundation emphasizes the importance of research that challenges conventional thought. Grants of $10,000 are awarded to curators collaborating with established non-profits, promoting impactful exhibitions. The foundation aims to foster family unity and respect while addressing enduring societal issues through art, environment, and learning differences.

The Society of Family Planning is offering the Bridging Investments in Abortion and Contraception Research Grant to support the completion of NIH grants focused on abortion and contraception. This funding aims to mitigate the impact of recent funding terminations by ensuring that vital research continues, promoting equitable access to reproductive health. Proposals can request up to $100,000 and must detail their alignment with the Society's mission, planned activities, and budget within a 24-month timeline.

The Installed Building Products Building for Tomorrow Scholarship, established by The Columbus Foundation, aims to support employees and their families in pursuing educational goals. Award amounts include $5,000 annually for the duration of a program or degree, with a special $10,000 scholarship for a candidate demonstrating the highest financial need. Open to anyone attending accredited institutions in the U.S., preference is given to those in construction-related fields.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is announcing a Notice of Funding Opportunity (NOFO) for Diabetes Research Centers (DRCs). These centers aim to foster collaboration among diabetes researchers, enhance preclinical and clinical research, and provide access to specialized resources. Emphasis is on innovative scientific themes and collaborative projects in areas such as Immunology and Artificial Intelligence. Although applications are not currently solicited, potential applicants are encouraged to prepare for future submissions.

Medina County Women's Scholarship FundOriginally established by the American Association of University Women of Medina County to award scholarships to nontraditional female students. A nontraditional student is a woman whose undergraduate education has been interrupted or delayed.Amount:

• Varies

Number of awards:

• Varies

Renewal:

• Must reapply annually by submission of a new application; however, any applicant cannot be selected more than twice for this scholarship.

National Federation of the Blind of Maryland

The National Federation of the Blind of West Virginia (NFBWV), an affiliate of the National Federation of the Blind, is an organization that believes in the full capacity of blind people, and has the power, influence, diversity and determination to help transform our dreams into reality. Members work together for a brighter tomorrow by raising expectations so that blind persons can live the life they want.

The National Federation of the Blind of West Virginia is a 501c(3) nonprofit volunteer membership organization comprised of blind and interested sighted persons of all ages, their families and friends. Our committed local chapters, divisions, committees, programs, and well-trained leaders help newly blind people adjust to vision loss, and promote the full participation and integration of blind people in our communities. We bring our collective experiences together to effect change at the state and national level.

Allen-Sprinkle Memorial Gift

Each year the National Federation of the Blind of West Virginia (NFBWV) awards a scholarship to a worthy blind individual who is pursuing or planning to pursue a full-time program of post-secondary study or training and is a resident of West Virginia. This award is known as the Allen-Sprinkle Memorial Gift. Both Sid Allen and Jack Sprinkle were long time leaders in the organized blind movement in West Virginia. The gift is One Thousand Dollars ($1,000.00), and the scholarship will be given at the annual banquet of the NFBWV State Convention.

The AHA Quest for Quality Prize recognizes hospitals and health systems that demonstrate exceptional leadership in improving care quality and advancing health. Applicants should showcase innovative models of care and effective partnerships with community organizations. One winner and two finalists will be honored at the 2026 AHA Leadership Summit in Denver. This award aims to inspire hospitals to commit to patient-centered care and address healthcare disparities, ultimately enhancing community health outcomes.

The Dale A. Nordquist Family Scholarship, offered by the St. Croix Valley Foundation, supports students from Clayton, Amery, or Clear Lake High Schools pursuing degrees or training in tech or trade fields. With a commitment to fostering local talent, this scholarship aims to empower future generations by investing in their education and career aspirations. The Foundation has a rich history of connecting local generosity with impactful initiatives that enhance community well-being across the St. Croix Valley.

The Gerald C. Corcoran Education Grant, offered by the North American Native Fishes Association (NANFA), supports educational projects focused on native fish ecology and conservation. With a generous matching grant from the Corcoran family, eligible NANFA members can receive up to $2000 biennially for various environmental education initiatives, including materials production, aquatic surveys, and teacher training workshops. This program honors the legacy of past NANFA President Gerald C. Corcoran, emphasizing the importance of public education in fish conservation.

The Marcia L. Wetherbee Scholarship, established by The Columbus Foundation, supports graduating high school seniors from central Ohio who plan to pursue higher education. With a minimum award of $1,000, this scholarship honors Marcia Wetherbee, a passionate community advocate and social worker. Eligible candidates must have a GPA between 2.5 and 3.8 and demonstrate commitment to their education. This scholarship aims to empower the next generation of leaders in the community.

The Robert L. and Pauline H. Minton Memorial Scholarship Fund, established by the children of Pauline H. Minton, honors their parents' legacy as dedicated Battelle employees and single parents. This scholarship aims to support children of full-time Battelle staff who are pursuing education at public or nonprofit colleges in the U.S. With an award amount of $1,000, it reflects a commitment to enhancing educational opportunities for deserving students in central Ohio.

The Open Ocean Research Grant Program, funded by Global Fishing Watch Inc, aims to enhance ocean governance through data sharing on human activity at sea. It invites researchers to improve technologies for better governance, offering up to $10,000 for individuals and $20,000 for small groups. This initiative strengthens the community of practice and optimizes Global Fishing Watch datasets to maximize their impact on ocean conservation efforts.

The American Journalism Project is dedicated to enhancing local news organizations by investing in their business capacities and providing personalized coaching. They prioritize diversity, equity, and inclusion, encouraging inquiries from organizations serving underrepresented communities. Their approach offers tailored support based on grantees' strategic challenges, fostering sustainable growth in revenue and programming. They seek grantees with strong public-service missions, independent 501(c)(3) status, and a commitment to transparency and accountability in their operations.

CAAM Fellowship

Maker and project development opportunity with a focus on nurturing mentor-fellow relationships within the Asian American documentary community.

The CAAM Fellowship Program aims to support documentary filmmakers developing Asian American stories by pairing selected Fellows with accomplished professionals as Mentors for six months to nurture both a project and the Fellow’s career in documentary filmmaking. 

These Mentors will be working one on one with their Fellows on their documentary projects and engage in virtual and in-person opportunities to nurture the full cohort. 

This year’s CAAM Fellowship is an opportunity to support filmmakers in the Midwest, a region that has been home to Asian Americans since before the U.S. was founded, especially for key sub-communities, such as the Hmong American community in Minneapolis, Michigan’s Muslim American communities, along with many others. This Fellowship continues CAAM’s commitment to uplifting nuanced, community-centered storytelling across the country.

The Fellowship includes one-on-one mentor meetings, monthly cohort gatherings, and participation in programs like the CAAMFest Filmmaker Summit and Ready, Set, Pitch! — building a lasting community of documentary makers.

Mission

The Mission of the Muskingum County Community Foundation is to improve quality of life in the community by nurturing opportunities and serving needs through collaboration and philanthropy.

Vision

The Envisioned Future of the Muskingum County Community Foundation is that Muskingum County’s quality of life attracts organizations and people to pursue their dreams and practice their passions.

A. Porter Spirit of ZHS Fund

A long time teacher at Zanesville High School. As a new teacher ZHS embraced her and she embraced the Blue Devils. Annette Porter is a first generation college graduate from a single parent home. While her parents supported her decision to go to college, it was necessary to incur personal debt which was and is common. This scholarship is available to help those students who may need a little financial help to take the first step toward college, and also make the collegiate experience less burdensome.

Becoming a Blue Devil was a process. Annette had a lot of help along the way, from Principals, Asst Principals, teaching peers, friends and family, so in an effort to pay it forward she has created this scholarship. “ Everyone of my students had potential, the most difficult thing was to convince them to work toward achieving it”. This scholarship will be awarded to a Blue Devil, not necessarily the most “spirited” but the Best Blue Devil who demonstrated all of the qualities that make up a Blue Devil.