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Best Large Grants for Nonprofit Organizations in Massachusetts

Find the perfect Large Grants for Nonprofit Organizations in Massachusetts on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in Massachusetts in the United States.

10,000+

Available grants

$2.65B

Total funding

$5K

Median grant

10,000+ grants
$2.65B total
$5K median

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9,710 Results based on applied filters

Stazer Sisters’ Scholarship

Erie Community Foundation
Private
United States
Unspecified amount
The Stazer Sisters’ Scholarship, provided by the Erie Community Foundation, supports U.S. citizens graduating from the Northwest Pennsylvania Collegiate Academy who are entering a four-year college. In 2023, over $800,000 was awarded to more than 500 students, based on their academic achievements, financial need, and extracurricular involvement. This scholarship aims to empower deserving students to achieve their educational goals and contribute positively to their communities.
Career / College Preparation Academic Scholarship Programs

Lou & Carol Calcagno Memorial Scholarship

Agri-Culture
Private
United States
US $1,000
The Lou & Carol Calcagno Memorial Scholarship offers a $1,000 award for students pursuing degrees in agriculture, Political Science, History, Marine Biology, Wildlife Management, or Culinary Arts. To be eligible, applicants must maintain a minimum GPA of 2.5 and reside in Santa Cruz or Monterey County, or be members of the Santa Cruz County Farm Bureau. The scholarship is awarded upon proof of college enrollment.
Career / College Preparation Academic Scholarship Programs

Teague-Gaudin OTA/SOMOS Active-Duty Military Traveling Fellowship

Orthopaedic Trauma Association
Association/Society
United States
Unspecified amount
The Teague-Gaudin OTA/SOMOS Active-Duty Military Traveling Fellowship supports early-career military orthopaedic trauma surgeons by providing immersive experiences in leading trauma centers. With a focus on education and mentorship, this fellowship enhances skills in advanced trauma care and fosters military-civilian collaboration. Funded by a generous $150,000 donation, it aims to empower surgeons through exposure to high-volume trauma systems, ultimately improving patient care in the orthopaedic trauma community.
Surgery Orthopedics Military & Veterans Services

Valley Hospital Auxiliary Scholarships

The Valley Hospital Inc
Private
United States
Unspecified amount
The Valley Hospital Auxiliary has been supporting future healthcare professionals since 1961 by providing scholarships to high school seniors and undergraduate students. In 2025, they awarded $30,000 to 21 exceptional students who have shown academic excellence and a commitment to healthcare. This initiative not only benefits the recipients but also contributes to the community by nurturing the next generation of medical leaders. Eligible high school students can reapply throughout their college years, ensuring continuous support for their educational journeys.
Academic Scholarship Programs College Success / Persistence

The Truman Scholarship

HARRY S TRUMAN SCHOLARSHIP FOUNDATION DEVELOPMENT FUND
Private
United States
Up to US $30,000
The Truman Scholarship, established by the Truman Foundation, supports college juniors committed to public service. It offers up to $30,000 for graduate studies, alongside mentoring and career development opportunities. Ideal candidates demonstrate leadership, a strong commitment to public service, and the potential for success in graduate school. This prestigious award aims to cultivate future leaders dedicated to making a positive impact in their communities and beyond.
Education - Higher Education Civic Leadership Development Academic Scholarship Programs

PCORI Call for Proposals for HSII Implementation Projects

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $2,500,000
The PCORI Call for Proposals for HSII Implementation Projects invites innovative approaches to address barriers in healthcare settings. These projects should enhance practice change through active, multi-component strategies and include rigorous evaluations to measure implementation effectiveness. While developing tools to support these strategies is permitted, it should not be the main focus. Successful proposals will demonstrate their potential impact on healthcare outcomes and patient experiences.
Medical Education & Professional Training Cardiovascular Diseases & Systems

NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens (360006)

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
American Samoa, Guam +4 more
Up to US $200,000
The NARMS Cooperative Agreement Program aims to enhance antibiotic resistance surveillance in retail food specimens. Funded by the FDA, this initiative strengthens the National Antimicrobial Resistance Monitoring System established in 1996. By improving detection methods and expanding sampling sites, the program seeks to protect public health and align with NARMS objectives, ultimately combating the growing threat of antibiotic resistance in food commodities.
Drug-Resistant Bacteria Epidemiology & Public Health

The PSN Labs Scholarship

Erie Community Foundation
Private
United States
Unspecified amount
The PSN Labs Scholarship, awarded by the Erie Community Foundation, supports seniors from Erie County schools who have a minimum GPA of 3.0 and are accepted into accredited four-year colleges. In 2023, the foundation allocated over $800,000 in scholarships to more than 500 students, helping them pursue their educational goals. This need-based scholarship aims to alleviate financial burdens and promote higher education among deserving students.
Career / College Preparation Academic Scholarship Programs

Tom Roberts Memorial Scholarship

Erie Community Foundation
Private
United States
Unspecified amount
The Tom Roberts Memorial Scholarship, offered by the Erie Community Foundation, supports high school seniors actively participating in baseball or softball with two annual scholarships. Honoring Tom Roberts' 40-year commitment to youth sports, applicants must maintain a minimum GPA of 3.25 and plan to pursue post-secondary education or training. In 2023, over $800,000 in scholarships were awarded to deserving students, highlighting the foundation's dedication to fostering educational opportunities.
Career / College Preparation Academic Scholarship Programs

AJO Forever Scholarship

Erie Community Foundation
Private
United States
Unspecified amount
The AJO Forever Scholarship, awarded by the Erie Community Foundation, supports well-rounded high school students who engage in various activities, including community service and part-time work. Applicants must plan to pursue a nursing degree and submit an essay detailing their motivations, along with a letter of recommendation. In 2023, the foundation allocated over $800,000 in scholarships to help more than 500 deserving students achieve their educational goals.
Career / College Preparation Academic Scholarship Programs

Kris Campbell “Any Dream Will Do” Scholarship Fund

Noble County Community Foundation
Private
United States
US $500
The Kris Campbell “Any Dream Will Do” Scholarship Fund offers a one-time $500 award to a Prairie Heights High School senior. Eligible students should have participated in the school drama club for at least two years or excelled in English, pursuing a related major in college. The scholarship supports students aiming for a Bachelor’s degree at any accredited institution, awarded upon proof of enrollment.
Career / College Preparation Academic Scholarship Programs

Yip Harburg Foundation Grant

The Yip Harburg Foundation Inc
Corporate
United States
US $500 - US $5,000
The Yip Harburg Foundation Grant supports projects that promote economic and social justice through grants and scholarships. This foundation honors the legacy of E.Y. "Yip" Harburg by funding theater programs that convey socially responsible messages. Grants range from $500 to $5,000 and are available to registered 501c3 organizations. Applications are reviewed quarterly, so interested parties should ensure their projects align with the foundation's mission.
Art for Social Change Music

John G. Blakesley Mathematical Excellence Scholarship for 8th Graders

Community Foundation of Elkhart County
Private
United States
Up to US $7,000
The John G. Blakesley Mathematical Excellence Scholarship is awarded annually to an exceptional eighth-grade student in Elkhart County. This four-year scholarship, totaling $5,000, supports higher education expenses and is funded by local businessman John Blakesley, who aims to empower future generations. Candidates are nominated by their schools and must demonstrate outstanding character, leadership, and a commitment to learning, reflecting the values cherished by Mr. Blakesley.
Career / College Preparation Academic Scholarship Programs

Paul & Barbara Bond College Scholarship

Erie Community Foundation
Private
United States
Unspecified amount
The Paul & Barbara Bond College Scholarship, offered by the Erie Community Foundation, supports graduating seniors from Erie City’s Public schools. Eligible students must have a GPA of 3.0 or higher and plan to pursue a bachelor’s degree in any field. In 2023, the foundation awarded over $800,000 in scholarships to more than 500 deserving students, reinforcing its commitment to enhancing educational opportunities in the community.
Career / College Preparation Academic Scholarship Programs

AAUW Community Action Grants

American Association of University Women (AAUW)
Association/Society
American Samoa, Guam +4 more
Up to US $50,000
The AAUW Community Action Grants provide up to $75,000 to support nonprofits and educational institutions that empower girls in grades K–12 to succeed in STEM fields. By fostering hands-on learning, mentorship, and family involvement, these grants aim to build confidence and skills among girls, especially those from underrepresented communities. AAUW believes that immersive STEM environments and relatable role models can inspire lasting interest and help close the gender gap in leadership and careers.
STEM / STEAM Education Education - K through 12 Women & Girl Services

Sociological Initiatives Foundation Grant

Sociological Initiatives Foundation Inc.
Private
United States
US $15,000 - US $30,000
The Sociological Initiatives Foundation Grant supports research linking social action to addressing systemic inequalities in the U.S., funding projects that tackle racism, classism, and human rights violations. It prioritizes initiatives that foster partnerships between academia and community organizations, aiming to enhance advocacy and public knowledge. Grants typically range from $15 to $25,000, emphasizing research with tangible community impacts rather than mere reporting. The Foundation seeks projects that can fundamentally change societal structures and improve equity.
Public Policy Social Justice / Human Rights Literacy +1 more

Corey C. Griffin Scholarship

Yellowstone Club Community Foundation
Private
United States
US $5,000
The Corey C. Griffin Scholarship, offered by the Yellowstone Club Community Foundation, awards two $5,000 scholarships to high school seniors. This initiative honors Corey C. Griffin’s legacy by recognizing students who embody his 'never quit' attitude and commitment to community service. Eligible applicants must attend specific high schools and have applied to a post-secondary institution. Note that children of Yellowstone Club employees at the Director level are not eligible for this merit-based scholarship.
Career / College Preparation Academic Scholarship Programs

Allison Summers Pediatric Pilot Grant

American Academy of Optometry Foundation Inc.
Corporate
United States
US $10,000
The American Academy of Optometry Foundation is inviting applications for the 2025-26 Allison Summers Pediatric Pilot Grant. This $10,000 grant aims to support mid-career optometrists in conducting pilot research that fosters new collaborations and innovative projects in pediatric optometry. Eligible candidates must be Fellows of the Academy and demonstrate a commitment to advancing pediatric research. The deadline for submitting the Letter of Intent is August 4, 2025.
Eye Diseases & Disorders Children’s Health & Pediatrics

Immunology and Immunotherapy SMRT Grant

Pacific Biosciences of California, Inc.
Corporate
United States
Up to US $12,000 in in-kind support
The Immunology and Immunotherapy SMRT Grant by Pacific Biosciences aims to enhance research through advanced sequencing technologies. This grant offers free sequencing to support innovative projects in immunology and immunotherapy, encouraging researchers to apply their findings to better understand the immune system and develop new therapies. With the opportunity to utilize highly accurate long-read sequencing, winners will gain access to state-of-the-art technology that can accommodate multiple libraries, enhancing their research outcomes significantly.
Immune System Diseases Genetics & Genomics

Goldman Fund: Education & Literacy

Lisa & Douglas Goldman Fund
Private
United States
Unspecified amount
The Lisa and Douglas Goldman Fund, established in 1992, focuses on enhancing education and literacy in the San Francisco community. It supports organizations classified as public charities with 501(c)(3) status, prioritizing projects that strengthen public education and promote civic education for grades K-12. Grant requests are by invitation only and are considered quarterly. The fund seeks to make informed, flexible grants that align with its mission to support impactful charitable projects.
Education - K through 12 Civic Engagement & Education Teacher Development & Training

Thomas L. McKenzie Research Award

Society Of Health And Physical Educators
Private
United States
Up to US $2,000
The Thomas L. McKenzie Research Award, offered by SHAPE America, supports emerging researchers in physical education and public health. With a funding pool exceeding $600,000 since 1997, it provides annual awards of up to $2,000 to graduate students and early career professionals (within 4 years of graduation) who are members of SHAPE America. The focus is on behavioral research related to physical activity, particularly in natural environments, contributing to disease prevention and promoting overall health.
Physical Fitness Health Policy & Advocacy

SHAPE America: Research Fellow Program

Society Of Health And Physical Educators
Private
United States
Unspecified amount
The SHAPE America: Research Fellow Program recognizes dedicated members for their significant contributions to health and physical education scholarship. Nominees must demonstrate excellence through impactful research, including a minimum of 10 peer-reviewed articles and participation in SHAPE America conventions. This prestigious designation promotes ongoing scholarship and encourages engagement within the diverse community of health and physical educators, enhancing professional practice and advancing the mission of SHAPE America.
Physical Fitness Health Policy & Advocacy

Lowell Teachers Scholarships

President And Fellows Of Harvard College
Private
United States
Unspecified amount
The Lowell Teachers Scholarships, offered by Harvard University, allow middle and high school teachers to enroll in one Extension School course per term at half the tuition cost. This initiative promotes professional development by making Harvard's rigorous academic programs accessible to educators. Limited scholarships are available, encouraging early application. Note that these scholarships cannot be used for summer courses or combined with other financial aid, ensuring focused support for teachers dedicated to enhancing their skills.
Education - Higher Education Adult Education Teacher Development & Training

SHAPE America: Mentor of the Year Award

Society Of Health And Physical Educators
Private
American Samoa, Guam +4 more
Unspecified amount
The SHAPE America: Mentor of the Year Award recognizes an exemplary role model committed to fostering student engagement in professional activities. Candidates must have a minimum of three years of membership in SHAPE America and serve as full-time faculty at a higher education institution. This award emphasizes mentorship through professional behavior, involvement in student projects, and providing academic guidance, ensuring that students are well-prepared for their future careers.
Education - K through 12 Sports & Athletics Academic Success & Enrichment

Garrett Francis Collins and Josephine Goodwin Collins Scholarship Fund

The Berkshire Taconic Community Foundation
Private
United States
Unspecified amount
The Garrett Francis Collins and Josephine Goodwin Collins Scholarship Fund, established by the Berkshire Taconic Community Foundation in 2015, supports high school seniors from Hinsdale, MA, pursuing higher education. This fund is part of a larger initiative that promotes economic mobility and community betterment, reflecting the foundation's commitment to philanthropy and leadership. With a rich history dating back to 1987, the foundation manages numerous funds to enhance the quality of life for residents across multiple regions.
Education - Higher Education Career / College Preparation

Carol Ann and Ralph V. Haile Jr. Scholarship Program

Carol And Ralph Haile Jr Foundation
Private
United States
Approximately US $5,312
The Carol Ann and Ralph V. Haile Jr. Scholarship Program, established by the Carol Ann and Ralph V. Haile Jr. Foundation in partnership with UNCF, supports students attending UNCF member institutions, HBCUs, or other accredited four-year colleges. This renewable merit-based scholarship aims to enhance educational opportunities for residents of specific counties in Kentucky, Ohio, and Indiana, particularly focusing on those majoring in education or STEM fields.
Education - Higher Education Academic Scholarship Programs STEM / STEAM Education

Quailwood Scholarship Fund

The Berkshire Taconic Community Foundation
Private
United States
Unspecified amount
The Quailwood Scholarship Fund, established by Jonathan Schor, aims to enhance public services and the quality of life in Red Rock, New York. Funded by the Berkshire Taconic Community Foundation, it provides grants for conservation, education, and community support. The advisory board, comprising local leaders and organizations, ensures that the fund meets the long-term needs of the community. The initiative fosters a strong sense of community and encourages diverse participation among residents, promoting economic mobility and a high quality of life.
Education - Higher Education Career / College Preparation

Large Grants for Nonprofit Organizations in Massachusetts Highlights

Looking for large grants for nonprofit organizations in Massachusetts?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Massachusetts recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Massachusetts

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Large Grants for Nonprofit Organizations in Massachusetts grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

95 Large Grants for Nonprofit Organizations in Massachusetts over $25K in average grant size

75 Large Grants for Nonprofit Organizations in Massachusetts over $50K in average grant size

60 Large Grants for Nonprofit Organizations in Massachusetts supporting general operating expenses

200+ Large Grants for Nonprofit Organizations in Massachusetts supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Massachusetts?

Most grants are due in the first quarter.

Q1
32.0%
Q2
24.4%
Q3
18.8%
Q4
24.8%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Massachusetts?

Grants are most commonly $26,875.

$250 $250 Min.
$26,875 $26.9 K Median
$413,560 $413.6 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Massachusetts?

Grants are most commonly $124,010.

$124,010

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Massachusetts year over year?

In 2024, funders in Massachusetts awarded a total of 105,825 grants.

2022 103,608

2023 102,118

2024 105,825

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Massachusetts given out in Massachusetts, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Massachusetts changing over time?

Funding has increased by 9.89%.

2022 $14,522,602,699

2023 $11,906,472,240
-18.01%

2024 $13,083,681,605
9.89%

Massachusetts Counties That Receive the Most Funding

How does grant funding vary by county?

Suffolk County, Middlesex County, and Norfolk County receive the most funding.

County Total Grant Funding in 2024
Suffolk County $7,016,988,269
Middlesex County $2,770,808,615
Norfolk County $554,651,103
Essex County $369,041,706
Worcester County $299,030,165