Best Large Grants for Nonprofit Organizations in Massachusetts

The Collins Medical Trust Grant, established in 1956, supports health-related research and professional education for tax-exempt organizations. Eligible applicants include institutions with approved tax status and a commitment to equal opportunity. Early career investigators are encouraged to apply, but funds cannot be used for individual benefits or political activities. The Trust prioritizes projects in Oregon and does not support product development for industry. Applications are accepted thrice yearly, with specific deadlines for timely consideration.

The Rehabilitation Engineering Research Center on Recreational, Sport, and Exercise Technologies for People with Disabilities aims to enhance rehabilitation services through innovative technological solutions. This initiative focuses on promoting health and exercise among individuals with disabilities by addressing unique rehabilitation challenges. Funded by the US HHS Administration for Community Living, the project spans 60 months, involving advanced research and development to create effective support mechanisms and overcome environmental barriers.

SeedMoney Challenge is a global crowdfunding initiative designed to support public food garden projects. Through a competitive 30-day challenge, participants can win grants ranging from $100 to $1000 based on the funds they raise. This program, operated by the non-profit SeedMoney, aims to empower communities by providing essential resources for food gardening efforts, thereby enhancing local food security and sustainability.

The Wilbur Awards, presented annually since 1949 by the Religion Communicators Council, celebrate excellence in communicating religious values and themes in secular media. Open to individuals and organizations, entries must have been published or broadcast in 2024. Categories include audio, audio-visual, images, and written works, allowing for both English and non-English submissions. The awards emphasize professionalism and respect in highlighting uplifting religious narratives within diverse media platforms.

About

Paul Newman was born and raised in Ohio by parents who owned a successful sporting goods store. He enlisted in the Navy and completed his military service as a radioman/gunner in the Pacific during World War II. Seeing his father’s business ethic during the Great Depression and experiencing the war fueled his desire to help others in need.

In 1958, Paul made his acting debut on Broadway in “Picnic,” where he also met his future wife, Joanne Woodward. Paul started a successful race car driving career inspired by training for the film Winning. He went on to win second place in the 24 Hours of Le Mans, the world’s oldest endurance race event. After years of acting and being recognized for his achievements on screen and stage, he received many accolades including an Oscar for Best Actor in The Color of Money.

Paul used his fame for good. He was dedicated to civil rights–attending the March on Washington in August 1963–women’s rights, and gay rights. He used his platform to advocate for equal pay for his female co-stars. He was a vocal political advocate committed to ending the nuclear arms race and determined to elect opponents of war and militarism. President Jimmy Carter appointed him to a United Nations General Assembly session on nuclear disarmament.

In 1982, Paul Newman and his friend Hotch founded a food company on a bit of a lark. They turned a profit selling salad dressing that first year, and did something truly radical when they decided to “give it all away” to good causes.

Paul established Newman’s Own Foundation to ensure the continuation of his philanthropic legacy after his passing. 40+ years since its founding, his first of its kind food company and its innovative business model are still going strong.

Garden Grants

Through Whole Foods Market’s Garden Grant program, schools turn outdoor spaces into powerful hands-on learning gardens that connect kids with food, spark their curiosity and support classroom curriculum.

The Creation & Development Fund, administered by the National Performance Network, supports the creation and mobility of artistic works that promote racial and cultural justice. It fosters collaboration between artists and communities through financial support, enabling artists to develop meaningful relationships and present their work. The fund emphasizes equity, access, and the importance of public engagement, ensuring that diverse voices are represented while addressing systemic injustices in the arts.

The DOJ FY 2026 ANGEL Grant Program aims to enhance public safety by funding state, local, and tribal government initiatives to combat violent crime committed by criminal illegal aliens. This program supports hiring law enforcement personnel, retaining critical staff, and acquiring advanced technology. The objective is to prevent harm to American citizens and support Homeland Security Task Force operations. Applications must be submitted by October 27, 2026, to qualify for funding.

The NIJ FY 2026 Research and Evaluation on School Safety funding opportunity aims to support essential research and evaluations focused on enhancing K-12 safety. Key areas of interest include anonymous reporting systems for threats of school violence and the establishment of threat assessment teams. Applicants are encouraged to collaborate with educators and communities to develop effective solutions and assess the impact of various safety initiatives, thereby contributing valuable insights to school safety practices.

The Community Heart & Soul Seed Grant Program offers $10,000 in startup funding for community-driven groups in small towns to adopt the Community Heart & Soul model. Applications are accepted until 11:59 p.m. EST on the last business day of each month, with funding decisions made the following month. This initiative aims to empower residents to engage in local development and foster community connections.

The NABG Scholarships support full-time undergraduate and graduate students in Geoscience programs at accredited institutions, with over $300,000 in funding raised through donations and events. Candidates must exhibit academic excellence, aiming to equip them for future careers in the geosciences. This initiative, backed by the National Association of Black Geoscientists, fosters diversity and prepares the next generation of professionals in the field.

The Sarah Bradley Tyson Memorial Fellowship, established in 1928, honors Sarah Tyson's commitment to women's agricultural education. It offers an annual scholarship to a full-time graduate student in agriculture or horticulture at an accredited U.S. institution. Eligible candidates must have relevant experience in these fields. This fellowship not only supports academic advancement but also aims to empower women pursuing careers in agriculture, reflecting Tyson's legacy of fostering education and community involvement.

The Presbyterian Committee on the Self-Development of People Grant supports partnerships with economically disadvantaged groups in the U.S. It aims to empower these communities to take control of their lives and address systemic issues of poverty and oppression. This initiative encourages sustainable change through community-led programs that advocate for justice, human dignity, and economic equity, fostering a transformative impact on their local environments.

The OpenAI A People-First AI Fund supports U.S.-based nonprofits with 501(c)(3) status, focusing on AI literacy, community innovation, and economic opportunity. It aims to enhance public understanding of AI, promote participatory design in AI applications by communities, and expand access to meaningful work through inclusive practices. Organizations at all stages of AI adoption are encouraged to apply, especially those addressing the needs of traditionally marginalized populations. This initiative emphasizes equitable distribution of AI benefits.

AmeriCorps Vista

AmeriCorps is the federal agency that improves lives, strengthens communities, and fosters civic engagement through service and volunteering. AmeriCorps brings people together to tackle the country’s most pressing challenges through national service and volunteerism. AmeriCorps members and AmeriCorps Seniors volunteers serve with organizations dedicated to the improvement of communities and those serving. AmeriCorps helps make service a cornerstone of our national culture.

Founded in 1965, AmeriCorps VISTA is a federal anti-poverty national service program designed to provide resources to nonprofit organizations and public agencies to strengthen efforts to address poverty and poverty-related problems in the United States. In 1993, VISTA was incorporated into the AmeriCorps network of national service programs administered by the Corporation for National and Community Service, now known as AmeriCorps.

AmeriCorps VISTA Request for Concept Paper

Projects must be developed in accordance with AmeriCorps VISTA core principles:

• an anti-poverty focus
• community empowerment
• sustainable solutions
• capacity building

Project applications must address one of the following areas:

• Economic Opportunity
• Healthy Futures
• Education
• Veteran and Military Families

Canon U.S.A Donations focuses on supporting local communities and environmental initiatives. Eligible organizations must have 501(c)(3) status and adhere to guidelines that prioritize youth support and environmental sustainability. Canon emphasizes good standing with charity watchdogs and will not consider requests for individual needs or certain types of fundraising activities. This initiative reflects Canon's commitment to corporate social responsibility and community engagement.

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

Bud & Katherine Rae Aviation Scholarship

The Bud and Katherine Rae Aviation Scholarship was organized by friends of the late Bernard “Bud” Rae in 1983 to honor his many years of service to the aviation community. Among the principal organizers and donors of the scholarship fund are the Aviation Division of the Saginaw County Sheriff’s Department, the Saginaw Valley Air Museum and Mrs. Katherine Rae.

The purposes of the scholarship are to assist in preparation for an aviation career, to promote safety in aviation through education, training and research, to promote scientific study of aviation-related phenomenon, to develop aviation-oriented community leaders and to perpetuate the spirit of community service personified by Bud Rae.

The Lyons & Snyder Legal Excellence Scholarship, offered by the San Antonio Area Foundation, supports students pursuing legal studies. Applicants must demonstrate teaching or counseling experience and maintain a minimum GPA of 2.5. This scholarship is available to those enrolled or planning to enroll in accredited community colleges or universities across the USA. Since 1964, the foundation has played a vital role in enhancing community welfare through educational grants and scholarships.

Mellon Foundation

The Andrew W. Mellon Foundation was established in 1969 to strengthen, promote, and defend the arts and humanities as essential to democratic societies. Throughout our history, Mellon has held true to our founding commitments, secure in our conviction that the arts and humanities are essential to the health of a multivocal and democratic society. From our earliest days, we have aspired to build partnerships with our grantees, offering expertise and counsel in addition to funding

In recent years, Mellon has expanded on these core principles by actively prioritizing social justice across all of our grantmaking. This strategic shift builds on our long history of advocating for and investing in expanded access to higher education, humanities, and the arts, and addressing historical inequities in these fields. Our vision for Mellon’s future includes a focus on justice for all in all that we do—rooted in the Foundation’s long-held historic belief in the impact and power of the arts and humanities. At Mellon, we make grants to actively support communities and ideas that unlock the power in the arts and humanities that helps connect us all.

Humanities in Place Grant Program

The Andrew W. Mellon Foundation actively works with our grantee partners and we are deeply immersed in the fields in which we invest. Our grants are designed to activate the spirit of learning through the creation and sharing of bold new ideas and the inspiration felt in art, expression, spaces, and scholarship. 

From Alaska to Guam and the Borderlands to the Midwest, America is a constellation of unique heritages, traditions, and stories. In communities of all sizes, people are striving to expand the ways we can understand and authentically engage with the history that is all around us. Our Humanities in Place grants fund place keepers, artists, institutions, and storytellers who shine a spotlight on historically overlooked sites, and the communities and stories that surround them. In doing so, they help broaden our shared understanding and open new paths to discover what unites us, what makes us unique, and what we can learn from one another.

The PEMV Community and Impact Grants, provided by the Martha's Vineyard Community Foundation, aim to support local nonprofit organizations through thoughtful grant-making processes. Grants range from $1,000 to $25,000, focusing on enhancing the quality of life in Martha's Vineyard. Eligible applicants include 501(c)(3) organizations and local government agencies. The foundation prioritizes well-planned initiatives with strong community support, ensuring that funding addresses pressing local needs.

About Us

The Arthur L. Carter Journalism Institute at NYU

We want to educate those who agree. Opportunities abound in the media world, but at NYU Journalism, the opportunity to do compelling work that informs, engages, and matters to the societies in which we live drives our faculty, motivates our students, and shapes our approach.

Those who find this their calling will discover encouragement, support, and an endless amount to learn at NYU. Our graduates are able to work anywhere their talents take them, and they do. Students come here not only to gain competence in the journalist’s craft but also the tools to make it better than it is. And those two things are the essence of what we teach.

Matthew Power Literary Reporting Award

Matthew Power was an award-winning journalist who reported empathetically on the human condition. He died in March 2014, while on assignment in Uganda.

About the Award

The Matthew Power Literary Reporting Award is a grant of $15,000 to support the work of a promising early-career nonfiction journalist on a story that uncovers truths about the human condition.

Offered for the first time in 2015, the Award has been endowed by individuals and organizations touched by the life and work of Matthew Power, a wide-roving and award-winning journalist who sought to live and share the experience of the individuals and places on which he was reporting. Power, a longtime friend of the Arthur L. Carter Journalism Institute, died in March 2014, while on assignment in Uganda.

The award proceeds from the recognition that many important stories need to be reported from afar, and that publications do not always have the resources to send a journalist where the story is. The money need not be used exclusively for travel, but we expect that most successful applications will include such expenses. A panel of NYU journalism professors, outside writers, and editors will review the proposals. Finalists will be asked to take part in an interview online.

The judges will be interested in perpetuating Power’s legacy, as his former editor Roger Hodge put it, of “strong, character-driven narratives with detailed scenes and lyrical description.” Power was always open to the absurdity that often attends politics and international affairs; he was always searching, as he put it, for “the human truth beneath the sorry facts.” Power’s ultimate ambition, he added, was literary beauty.

That said, judges will be looking for a journalist as singular in his or her own approach as Power was in his. In addition to longform print projects, we will consider audio projects involving substantial reporting and running over 20 minutes in length. The award will not fund proposals to report on armed conflicts where journalists are already imperiled, nor projects that are mainly investigatory. The winner will normally receive visiting scholar privileges at NYU, including library access.

The Teacher Professional Development Grants (6-8), offered by the National Council of Teachers of Mathematics, aim to enhance the teaching skills of classroom teachers in grades 6-8. This grant supports professional development initiatives that focus on improving mathematics instruction. Eligible applicants must have at least three years of teaching experience and spend a majority of their time teaching in the classroom. The program encourages high-quality mathematics education for all students.

Our Consortium

ROAR (Rare Organic Acidemias Research) is a multi‑center study that brings together patients, families, clinicians, and researchers to better understand rare organic acidemias such as PA, MMA, GA‑1, IVA, and others. Our goal is to improve lifelong care and future treatment options for the rare disease community.

ROAR works in partnership with patient organizations, clinicians, and research networks to ensure that study findings are shared, accessible, and meaningful. Families play a central role in shaping our questions and informing our direction.

Rare Organic Acidemias Research (ROAR) Consortium Pilot and Feasibility Grants

The overall mission of the ROAR pilot & feasibility grant is to support small projects which advance diagnosis, enhance clinical trial readiness, and improve therapies and outcomes for individuals with organic acidemias. Potential pilot projects may include data-mining of existing data, genotype-phenotype correlations, observational studies, patient-reported outcomes assessments, focus groups with patients and advocacy groups, interventional clinical trials (with prior NIH approval), biomarker studies, ancillary studies to ROAR clinical projects, or other similar projects. Upon completion of funding, we expect that the data generated from ROAR pilot projects will be leveraged for larger grant applications and larger projects within and outside the consortium. Moreover, we expect that the data generated will inform the design of future clinical trials and clinical studies in organic acidemias and ultimately, will impact the lives of individuals with organic acidemias by improving the diagnosis, management, and treatment for these disorders. 

Annual funding of up to $40,000 (total cost, including indirect costs) is available to support one pilot project for a one-year period. The ROAR Consortium intends to fund at least 1 award this cycle starting on October 15, 2026.

The Grades 7-12 Preservice Teacher Coursework Scholarship, provided by the National Council of Teachers of Mathematics, offers financial support for students preparing to teach secondary school mathematics. Eligible candidates must be college sophomores or graduate students with a minimum GPA of 3.0. This scholarship aids in funding coursework and graduation within two to three years, ensuring a robust pipeline of qualified mathematics educators.

Larimer County Scholarship

The Larimer County Scholarship is designed to support post-secondary pursuits of students throughout the region and is funded through contributions from many community members and legacy gifts. 

The Larimer County scholarship is available to students who have participated in community or philanthropic activities designed to strengthen our community. Activities could include volunteering or fundraising to provide funding to local nonprofits or school-based initiatives.   

This scholarship is available to high school seniors living in Larimer County. The scholarship is open to students pursuing any kind of secondary education including four-year degrees, two-year degrees, trade schools, etc. 

Scholarship amount:

• $4,000

Number of awards:

• 3

Scholarship awards are one-time awards. The amount awarded to a selected recipient may be used for the cost of attendance. All scholarships will be paid directly to the recipient’s school and must be used for the upcoming academic year. Award disbursement is contingent upon the outside scholarship policies of a recipient’s college or university.

The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Data Coordinating Center aims to enhance understanding of inflammatory bowel disease (IBD) by coordinating extensive genetic research. By leveraging diverse patient cohorts and advanced data science techniques, the center seeks to identify genetic risk factors, develop predictive biomarkers, and improve IBD patient management. This initiative will facilitate collaboration among various research centers and ensure efficient data collection and sharing to foster advancements in precision medicine for IBD.

Golden Garden Scholarship

The Golden Garden Scholarship supports Monticello, Buckingham and Louisa high school seniors who plan to attend a two‑year community college or a four‑year university as full‑time students. Established to support first‑generation college students—particularly students of color—with financial need, the award provides $2,500 per year, renewable for up to four years, and seeks candidates who demonstrate an interest in the Arts & Humanities, have a minimum 2.75 high‑school GPA, and a commitment to healthy lifestyle choices. They must remain enrolled full‑time throughout the scholarship term, and uphold good character and citizenship.

The Opening Gates for Prospective Teachers Grant, established by the National Council of Teachers of Mathematics, aims to honor Dr. James Gates by funding electronic student memberships for prospective mathematics teachers from PreK-12. This initiative supports the council's mission to enhance mathematics education by providing resources for future educators. Eligible applicants include leaders of teacher preparation programs who are NCTM members and actively involved in certifying teacher candidates in mathematics or related fields.